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| 1 | Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD. | Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele | 2009 | World Journal of Gastroenterology2009，15，10： | 20 |
| 2 | 创伤患者的呼吸道管理显示文摘 | Peter D.Danne Michael Hunter Allan D.F.MackKillp 高建川 丁一妹 孙永华 经世弟 | 2008 | 中华损伤与修复杂志(电子版)2008，3，3： | 3 |
| 3 | Religion and attitudes toward the environment: a comparison of Mormons and the general U.S. population显示文摘 | Lori M. Hunter Michael B. Toney | 2004 | The Social Science Journal2004，，1： | 2 |
| 4 | Endostatin improves radioresponse and blocks tumor revascularization after radiation therapy for A431 xenografts in mice显示文摘 | Satoshi Itasaka Ritsuko Komaki Roy S. Herbst Keiko Shibuya Tomoaki Shintani Nancy R. Hunter Amir Onn Corazon D. Bucana Luka Milas K. Kian Ang Michael S. O’Reilly | 2007 | International Journal of Radiation Oncology, Biology, Physics2007，，： | 1 |
| 5 | Predictive value of noninvasivelydetermined endothelial dysfunction for long-term cardiovascular events inpatients with peripheral vascular disease显示文摘 | Noyan Gokce John F Keaney Liza M Hunter Michael T Watkins Zoran S Nedeljkovic James O Menzoian Joseph A Vita | 2003 | Journal of the American College of Cardiology2003，，： | 1 |
| 6 | Interpretation of FNA processed by the Thinprep technique Cytologic artifacts and diagnostic pitfalls显示文摘 | Michael CW Hunter B | | 0，，： | 1 |
| 7 | Chalcone synthase as a reporter in virus-induced gene silencing studies of flower senescence显示文摘 | Jen-Chih Chen Cai-Zhong Jiang Timothy Gookin Donald Hunter David Clark Michael Reid | 2004 | Plant Molecular Biology2004，，4： | 1 |
| 8 | John Evelyn and His Milieu 显示文摘 | Harris France Michael Hunter | 2003 | London:The British Library2003，，7： | 1 |
| 9 | Interpretation of FNA processed by the Thinprep technique Cytologic artifacts and diag- nostc pitfalla显示文摘 | Michael CW Hunter B | 2000 | Diagn Cytopathol2000，23，1： | 1 |
| 10 | Confocal Endomicroscopy in Ulcerative Colitis: Differentiating Dysplasia-Associated Lesional Mass and Adenoma-Like Mass显示文摘 | David P. Hurlstone Mike Thomson S. Brown Nick Tiffin Simon S. Cross Michael D. Hunter | 2007 | Clinical Gastroenterology and Hepatology2007，，10： | 1 |
| 11 | Physical properties of sediment from the Mount Elbert Gas Hydrate Stratigraphic Test Well, Alaska North Slope显示文摘 | William Winters Michael Walker Robert Hunter Timothy Collett Ray Boswell Kelly Rose William Waite Marta Torres Shirish Patil Abhijit Dandekar | 2010 | Marine and Petroleum Geology2010，，2： | 1 |
| 12 | Measuring Control Delay Components Using Second-by-Second GPS Speed Data显示文摘 | Joonho Ko Michael Hunter | 2007 | Journal of Transportation Engineering2007，134，： | 1 |
| 13 | Genes controlling seed dormancy and pre-harvest sprouting in a rice-wheat-barley comparison显示文摘 | Chengdao Li Peixiang Ni Michael Francki Adam Hunter Yong Zhang David Schibeci Heng Li Allen Tarr Jun Wang Mehmet Cakir Jun Yu Matthew Bellgard Reg Lance Rudi Appels | 2004 | Functional & Integrative Genomics2004，，2： | 1 |
| 14 | Functional Development of the Mammary Gland: Use of Expression Profiling and Trajectory Clustering to Reveal Changes in Gene Expression During Pregnancy, Lactation, and Involution显示文摘 | Michael C. Rudolph James L. McManaman Larry Hunter Tzulip Phang Margaret C. Neville | 2003 | Journal of Mammary Gland Biology and Neoplasia2003，，3： | 1 |
| 15 | Training for minimally invasive surgery显示文摘 | Bruce M. Wolfe Zoltan Szabo Michael E. Moran Paul Chan John G. Hunter | 1993 | Surgical Endoscopy1993，，2： | 1 |
| 16 | A Probe-Vehicle-Based Evaluation of Adaptive TrafficSignal Control显示文摘 | Hunter Michael P Wu Seung Kook Kim Hoe Kyoung etal | 2012 | IEEE Transactions on Intelligent Transpor-tation Systems2012，6，2： | 1 |
| 17 | Elimination of equivalence point errors in the potentiometric titration of chloride, bromide and iodide mixtures with silver nitrate 显示文摘 | Michael J Ellwood Keith A Hunter Robert G | 2003 | Microchemical Journal2003，74，： | 1 |
| 18 | Functional Development of the Mammary Gland: Use of Expression Profiling and Trajectory Clustering to Reveal Changes in Gene Expression During Pregnancy, Lactation, and Involution显示文摘 | Michael C. Rudolph James L. McManaman Larry Hunter Tzulip Phang Margaret C. Neville | 2003 | Journal of Mammary Gland Biology and Neoplasia2003，，3： | 1 |
| 19 | Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice显示文摘 | Michael Dellinger Robert Hunter Michael Bernas | 2008 | Dev boil2008，15，2： | 1 |
| 20 | Mesh complications after prosthetic reinforcement of hiatal closure: a 28-case series显示文摘 | Rudolf J. Stadlhuber Amr El Sherif Sumeet K. Mittal Robert J. Fitzgibbons L. Michael Brunt John G. Hunter Tom R. DeMeester Lee L. Swanstrom C. Daniel Smith Charles J. Filipi | 2009 | Surgical Endoscopy2009，，6： | 1 |
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