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52篇 您的检索式:作者名="Monville"
    题名 作者 年代 出处 被引量
1ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome显示文摘Christophe Ginestier Min Hee Hur Emmanuelle Charafe-Jauffret Florence Monville Julie Dutcher Marty Brown Jocelyne Jacquemier Patrice Viens Celina G. Kleer Suling Liu Anne Schott Dan Hayes Daniel Birnbaum Max S. Wicha Gabriela Dontu 2007Cell Stem Cell2007,,5:5
2Use of human pluripotent stem cells to study and treat retinopathies显示文摘Human cell types affected by retinal diseases(such as age-related macular degeneration or retinitis pimentosa) are limited in cell number and of reduced accessibility. As a consequence, their isolation for in vitro studies of disease mechanisms or for drug screening efforts is fastidious. Human pluripotent stem cells(h PSCs), either of embryonic origin or through reprogramming of adult somatic cells,represent a new promising way to generate models of human retinopathies, explore the physiopathological mechanisms and develop novel therapeutic strategies. Disease-specific human embryonic stem cells were the first source of material to be used to study certain disease states. The recent demonstration that human somatic cells, such as fibroblasts or blood cells, can be genetically converted to induce pluripotent stem cells together with the continuous improvement of methods to differentiate these cells into disease-affected cellular subtypes opens new perspectives to model and understand a large number of human pathologies, including retinopathies. This review focuses on the added value of h PSCs for the disease modeling of human retinopathies and the study of their molecular pathological mechanisms. We also discuss the recent use of these cells for establishing the validation studies for therapeutic intervention and for the screening of large compound libraries to identify candidate drugs.Karim Ben M'Barek Florian Regent Christelle Monville 2015World Journal of Stem Cells2015,7,3:2
3Gene expression profiling of breast cell lines identifies potential new basal markers显示文摘Charafe-Jauffret E Ginestier C Monville F 2006Oncogene2006,25,15:1
4Lentiveetor-mediated delietof GDNF protects complex motor funclions relevant to human Parkinsonism in a rat lesion model显示文摘Dowd E Monville C Torres EM 2005Eur J Neurosci2005,,:1
5Cancer Stem Cells in Breast: Current Opinion and Future Challenges显示文摘Charafe-jauffret Emmanuelle Monville Florence Ginestier Christophe Dontu Gabriela Birnbaum Daniel Wicha Max S 2008Pathobiology2008,,2:1
6Nectin-4 is a new histological and serological tumor associated marker for breast cancer显示文摘Fabre-Lafay S Monville F Garrido-Urbani S 2007BMC Cancer2007,7,73:1
7Gene expression profiling of breast cell lines identifies potential new basal markers显示文摘Charafe-Jauffret E Ginestier C Monville F 2006Oncogene2006,25,:1
8Lentivector-mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model显示文摘Dowd E Monville C Torres EM 2005Eur J Neurosci2005,22,:1
9Retinoid signaling regulates breast cancer stem cell differentiation显示文摘Christophe Ginestier Julien Wicinski Nathalie Cervera Florence Monville Pascal Finetti Fran?ois Bertucci Max S. Wicha Daniel Birnbaum Emmanuelle Charafe-Jauffret 2009Cell Cycle2009,,20:1
10Cancer stem cells in breast:current opinion and future challenges 显示文摘Charafe - Jauffret E Monville F Ginestier C 2008Pathobiology2008,75,2:1
11Cancer stem ceils in breast: current opinion and future challenges 显示文摘CHARAFE-JAUFFRET E MONVILLE F GINESTIER C 2008Pathobiology2008,75,2:1
12Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration显示文摘Mittoux V Ouary S Monville C Lisovoski F Poyot T Conde F 2002J Neurosci2002,22,11:1
13Cancer stem cells in breast:current opinion and future challenges 显示文摘Charafe-Jauffret E Monville F Ginestier C 2008Pathobiology2008,75,2:1
14Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer 显示文摘Jacquemier J Charafe-Jauffret E Monville F 2009Breast Cancer Res2009,11,2:1
15Nectin-4 is a new histological and serological tumor associated marker for breast caneer显示文摘Fabre-Lafay S Monville F Garrido-Urbani S 2007BMC Cancer2007,7,2:1
16Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration显示文摘Mittoux V Ouary S Monville C Lisovoski F Poyot T Conde F 2002J Nenrosci2002,22,11:1
17Delivery of sonic hedgehog or glial derived neurotrophic factor to dopamine-rich grafts in a rat model of Parkinson's disease using adenoviral vectors Increased yield of dopamine cells is dependent on embryonic donor age显示文摘Torres EM Monville C Lowenstein PR 2005Brain Res Bull2005,68,12:1
18Moesin expression is a marker of basal breast carcinomas显示文摘Charafe-Jauffret E Monville F Bertucci F 0,,08:1
19Gene ex- pression profiling of breast cell lines identifies potential new basal markers显示文摘Charafe-Jauffret E Ginestier C Monville F 2006Oncogene2006,25,15:1
20Nectin -4 is a new histological and serological tumor associated marker for breast cancer 显示文摘Fabre- Lafay S Monville F Garrido - Urbani S 2007BMC Cancer2007,7,:1
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