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| 1 | Do inhaled corticosteroids increase the risk of Pneumocystis pneumonia in people with lung cancer?显示文摘Pneumocystis pneumonia(PCP) is a life-threatening infection in immunocompromised patients. It is relatively uncommon in patients with lung cancer. We report a case of PCP in a 59-year-old man with a past medical history of chronic obstructive pulmonary disease treated with formoterol and a moderate daily dose of inhaled budesonide. He had also advanced stage non-small lung cancer treated with concurrent chemo-radiation with a cisplatin-etoposide containing regimen. The diagnosis of PCP was suspected based on the context of rapidly increasing dyspnea, lymphopenia and the imaging findings. Polymerase chain reaction testing on an induced sputum specimen was positive for Pneumocystis jirovecii. The patient was treated with oral trimethoprim-sulfamethoxazole and systemic corticotherapy and had showed clinical and radiological improvement. Six months after the PCP diagnosis, he developed a malignant pleural effusion and expired on hospice care. Through this case, we remind the importance of screening for PCP in lung cancer patients under chemotherapeutic regimens and with increasing dyspnea. In addition, we alert to the fact that long-term inhaled corticosteroids may be a risk factor for PCP in patients with lung cancer. Despite intensive treatment, the mortality of PCP remains high, hence the importance of chemoprophylaxis should be considered. | Sameh Msaad Ilhem Yangui Najla Bahloul Narjes Abid Makram Koubaa Yosr Hentati Mounir Ben Jemaa Samy Kammoun | 2015 | World Journal of Clinical Cases2015，3，9： | 5 |
| 2 | Significance of platelet count in children admitted with bronchiolitis显示文摘AIM To determine the true prevalence of thrombocytosis in children less than 2 years of age with bronchiolitis,its association with risk factors,disease severity and thromboembolic complications.METHODS A retrospective observational medical chart review of 305 infants aged two years or less hospitalized for bronchiolitis.Clinical outcomes included disease severity,duration of hospital stay,admission to pediatric intensive care unit,or death.They also included complications of thrombocytosis,including thromboembolic complications such as cerebrovascular accident,acute coronary syndrome,deep venous thrombosis,pulmonary embolus,mesenteric thrombosis and arterial thrombosis and also hemorrhagic complications such as bleeding(spontaneous hemorrhage in the skin,mucous membranes,gastrointestinal,respiratory,or genitourinary tracts).RESULTS The median age was 4.7 mo and 179 were males(59%).Respiratory syncytial virus was isolated in 268(84%),adenovirus in 23(7%) and influenza virus A or B in 13(4%).Thrombocytosis(platelet count > 500 × 109/L) occurred in 88(29%;95%CI:24%-34%),more commonly in younger infants with the platelet count declining with age.There was no significant association with the duration of illness,temperature on admission,white blood cell count,serum C-reactive protein concentration,length of hospital stay or admission to the intensive care unit.No death,thrombotic or hemorrhagic events occurred.CONCLUSION Thrombocytosis is common in children under two years of age admitted with bronchiolitis.It is not associated with disease severity or thromboembolic complications. | Amar Al Shibli Najla Alkuwaiti May Hamie Dima Abukhater Muhammad B Noureddin Abdulla Amri Salwa Al Kaabi Aysha Al Kaabi Mariam Harbi Hassib Narchi | 2017 | World Journal of Clinical Pediatrics2017，6，2： | 3 |
| 3 | Superselective embolisation of bilateral superior vesical arteries for management of intractable hematuria in context of metastatic bladder cancer显示文摘Hematuria due to locally advanced or metastatic bladder cancer is a common condition and is often a management problem.Percutaneous embolisation is a mini-invasive option to handle this situation.We report a case of a patient with a metastatic bladder cancer and who presented with an abundant hematuria and severe anemia.After failure of endoscopic resections and“flush”of radiotherapy haemostatic and refusal of cystectomy by the patient,he was treated by superselective embolisation of bilateral superior bladder arteries with excellent immediate results.The technique is safe and effective in the short term.The longterm effectiveness requires further investigation. | Ahmed Saadi Abderrazak Bouzouita Mohamed Hedi Rebai Mohamed Cherif Walid Kerkeni Haroun Ayed Amine Derouiche Hatem Rajhi Riadh Ben Slama Najla Mnif Mohamed Chebil | 2017 | Asian Journal of Urology2017，4，2： | 2 |
| 4 | Patients direct costs to undergo TB diagnosis显示文摘Background:A major impediment to the treatment of TB is a diagnostic process that requires multiple visits.Descriptions of patient costs associated with diagnosis use different protocols and are not comparable.Methods:We aimed to describe the direct costs incurred by adults attending TB diagnostic centres in four countries and factors associated with expenditure for diagnosis.Surveys of 2225 adults attending smear-microscopy centres in Nigeria,Nepal,Ethiopia and Yemen.Adults>18 years with cough>2 weeks were enrolled prospectively.Direct costs were quantified using structured questionnaires.Patients with costs>75^(th) quartile were considered to have high expenditure(cases)and compared with patients with costs<75^(th) quartile to identify factors associated with high expenditure.Results:The most significant expenses were due to clinic fees and transport.Most participants attended the centres with companions.High expenditure was associated with attending with company,residing in rural areas/other towns and illiteracy.Conclusions:The costs incurred by patients are substantial and share common patterns across countries.Removing user fees,transparent charging policies and reimbursing clinic expenses would reduce the poverty-inducing effects of direct diagnostic costs.In locations with limited resources,support could be prioritised for those most at risk of high expenditure;those who are illiterate,attend the service with company and rural residents. | Rachel M.Anderson de Cuevas Lovett Lawson Najla Al-Sonboli Nasher Al-Aghbari Isabel Arbide Jeevan B.Sherchand Emenyonu E.Nnamdi Abraham Aseffa Mohammed A.Yassin Saddiq T.Abdurrahman Joshua Obasanya Oladimeji Olanrewaju Daniel Datiko Sally J.Theobald Andrew Ramsay S.Bertel Squire Luis E.Cuevas | 2016 | Infectious Diseases of Poverty2016，5，1： | 1 |
| 5 | Effect of gammaray on activity and stability of alcohol-dehydrogenase from Sac charomyces cerevisiae 显示文摘 | NAJLA B A AMEL Z SONIA M | 2008 | Biochemical Engineering Journal2008，40，1： | 1 |
| 6 | Thermogravimetric analysis and kinetics modeling of isothermal carbonization of olive wood in inert atmosphere 显示文摘 | Najla Grioui Kamel Halouani Andre Zoulalian | 2006 | Thermochimica Acta2006，440，1： | 1 |
| 7 | Correlation of SMN 2, NAIP , p44 , H4F5 and Occludin genes copy number with spinal muscular atrophy phenotype in Tunisian patients显示文摘 | Abdelbasset Amara Labiba Adala Ilhem Ben Charfeddine Ons Mama? Amira Mili Taheni Ben Lazreg Dorra H’mida Fathi Amri Najla Salem Lamia Boughammura Ali Saad Moez Gribaa | 2011 | European Journal of Paediatric Neurology2011，，2： | 1 |
| 8 | A comparative study between parabolic trough collector and linear Fresnel reflector technologies显示文摘 | Najla E1 Gharbi Halima Derbal Sofiane Bouaichaoui Noureddine Said | 2011 | Ener gy Procedia2011，，6： | 1 |
| 9 | The multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasis显示文摘 | Najla Arshad Sandhya S. Visweswariah | 2012 | FEBS Letters2012，，18： | 1 |
| 10 | Solvent effects on phenolic contents and biological activities of the halophyte Limoniastrum monopetalum leaves 显示文摘 | Najla Trabelsi Wided Megdiche Riadh Ksouri | 2010 | LWT- Food Science and Technology2010，，43： | 1 |
| 11 | Effect ofvacuum packaging and low-dose irradiation on the microbial,chemical and sensory characteristics of chub mackerel (Scomber japonicus)显示文摘 | Raouf Mbarki Najla Ben Miloud Salah Selmi | | 0，，： | 1 |
| 12 | Artemisia campestris phenolic compounds have antioxidant and antimicrobial activity显示文摘 | Wided Megdiche-Ksouri Najla Trabelsi Khaoula Mkadmini Soumaya Bourgou Amira Noumi Mejdi Snoussi Rahma Barbria Olfa Tebourbi Riadh Ksouri | 2015 | Industrial Crops & Products2015，，： | 1 |
| 13 | Receptor guanylyl cyclase C (GC-C): regulation and signal transduction显示文摘 | Nirmalya Basu Najla Arshad Sandhya S. Visweswariah | 2010 | Molecular and Cellular Biochemistry . 2010 (1-2)2010，，1： | 1 |
| 14 | Evaluation of antioxidant activities of the edible and medicinal Suaeda species and related phenolic compounds显示文摘 | Samia Oueslati Najla Trabelsi Mondher Boulaaba | 2012 | Industrial Crops and Products2012，36，： | 1 |
| 15 | Supplier selection and order lot sizing modeling: A review 显示文摘 | Najla Aissaoui Mohamed Haouari Elkafi Hassini | 2007 | Computers & Operations Research2007，34，12： | 1 |
| 16 | Protective effects of garlic ( Allium sativum ) extract upon lindane-induced oxidative stress and related damages in testes and brain of male rats显示文摘 | Najla Hfaiedh Jean-Claude Murat Abdelfettah Elfeki | 2011 | Pesticide Biochemistry and Physiology2011，，2： | 1 |
| 17 | Prevalence of Bordetella pertussis and Bordetella parapertussis infections in Tunisian hospitalized infants: results of a 4-year prospective study显示文摘 | Asma Zouari Hanen Smaoui Delphine Brun Elisabeth Njamkepo Soufien Sghaier Emna Zouari Renaud Félix Khaled Menif Najla Ben Jaballah Nicole Guiso Amel Kechrid | 2012 | Diagnostic Microbiology & Infectious Disease2012，，4： | 1 |
| 18 | A comparison of 3D interest point descriptors with application to airport baggage object detection in complex CT imagery显示文摘 | Greg Flitton Toby P. Breckon Najla Megherbi | 2013 | Pattern Recognition2013，，9： | 1 |
| 19 | Receptor guanylyl cyclase C (GC-C): regulation and signal transduction显示文摘 | Nirmalya Basu Najla Arshad Sandhya S. Visweswariah | 2010 | Molecular and Cellular Biochemistry2010，，1： | 1 |
| 20 | An architecture and a method for Web services design:Towards the realisation of service-oriented computing显示文摘 | Youcef Baghdadi Najla Nasser Al-Rawahi | 2006 | International Journal of Web and Grid Services2006，2，2： | 1 |
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