|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 一种形态类似于黏液性平滑肌肉瘤的新型高级别子宫内膜间质肉瘤显示文摘子宫内膜间质肉瘤占子宫恶性肿瘤的1%,占子宫恶性间叶肿瘤的15%。WHO(2014)生殖肿瘤分类将子宫内膜间质肉瘤分为低级别子宫内膜间质肉瘤、高级别子宫内膜间质肉瘤及未分化子宫肉瘤。子宫内膜间质肉瘤常因频发染色体易位,致使发生参与表观遗传调控相关的基因融合。迄今为止,仅发现YWHAE-NUTM2重排与明确的高级别形态学及侵袭性临床行为密切相关。 | Hoang L N Aneja A Niamh C 黄爱清 余英豪 | 2017 | 临床与实验病理学杂志2017，33，7： | 9 |
| 2 | Carboxypeptidase E (NF-α1):a new trophic factor in neuroprotection显示文摘Carboxypeptidase E(CPE) is a prohormone-processing enzyme and sorting receptor that functions intracellularly.However, recent studies have demonstrated that CPE acts as a trophic factor extracellularly to up-regulate the expression of a pro-survival gene.This mini-review summarizes the roles of CPE in neuroprotection and the implications for neurodegenerative diseases. | Yong Cheng Niamh X.Cawley Y.Peng Loh | 2014 | Neuroscience Bulletin2014，30，4： | 3 |
| 3 | Total hepatectomy and liver transplantation as a two-stage procedure for fulminant hepatic failure: A safe procedure in exceptional circumstances显示文摘AIM: To evaluate the outcomes of two-stage liver transplant at a single institution, between 1993 and March 2015.METHODS: We reviewed our institutional experience with emergency hepatectomy followed by transplantation for fulminant liver failure over a twenty-year period. A retrospective review of a prospectively maintained liver transplant database was undertaken at a national liver transplant centre. Demographic data, clinical presentation, preoperative investigations, cardiocirculatory parameters, operative and postoperative data were recorded.RESULTS: In the study period, six two-stage liver transplants were undertaken. Indications for transplantation included acute paracetamol poisoning(n = 3), fulminant hepatitis A(n = 1), trauma(n = 1) and exertional heat stroke(n = 1). Anhepatic time ranged from 330 to 2640 min. All patients demonstrated systemic inflammatory response syndrome in the first post-operative week and the incidence of sepsis was high at 50%. There was one mortality, secondary to cardiac arrest 12 h following re-perfusion. Two patients required re-transplantation secondary to arterial thrombosis. At a median follow-up of 112 mo, 5 of 6 patients are alive and without evidence of graft dysfunciton.CONCLUSION: Two-stage liver transplantation represents a safe and potentially life-saving treatment for carefully selected exceptional cases of fulminant hepatic failure. | Rebeca Sanabria Mateos Niamh M Hogan Dimitri Dorcaratto Helen Heneghan Venkatesh Udupa Donal Maguire Justin Geoghegan Emir Hoti | 2016 | World Journal of Hepatology2016，8，4： | 3 |
| 4 | Current knowledge and future directions of TLR and NOD signaling in sepsis显示文摘The incidence of sepsis is increasing over time, along with an increased risk of dying from the condition. Sepsis care costs billions annually in the United States. Death from sepsis is understood to be a complex process, driven by a lack of normal immune homeostatic functions and excessive production of proinflammatory cytokines, which leads to multi-organ failure. The Toll-like receptor(TLR) family, one of whose members was initially discovered in Drosophila, performs an important role in the recognition of microbial pathogens. These pattern recognition receptors(PRRs), upon sensing invading microorganisms, activate intracellular signal transduction pathways. NOD signaling is also involved in the recognition of bacteria and acts synergistically with the TLR family in initiating an efficient immune response for the eradication of invading microbial pathogens. TLRs and NOD1/NOD2 respond to different pathogenassociated molecular patterns(PAMPs). Modulation of both TLR and NOD signaling is an area of research that has prompted much excitement and debate as a therapeutic strategy in the management of sepsis. Molecules targeting TLR and NOD signaling pathways exist but regrettably thus far none have proven efficacy from clinical trials. | Niamh M Foley Jian Wang H Paul Redmond Jiang-Huai Wang | 2014 | Journal of Medical Colleges of PLA(China)2014，29，4： | 2 |
| 5 | Heart-Type Fatty Acid-Binding Protein Predicts Long-Term Mortality and Re-Infarction in Consecutive Patients With Suspected Acute Coronary Syndrome Who Are Troponin-Negative显示文摘 | Karthik Viswanathan Niamh Kilcullen Christine Morrell Sue J. Thistlethwaite Mohan U. Sivananthan Tajek B. Hassan Julian H. Barth Alistair S. Hall | 2010 | Journal of the American College of Cardiology2010，，23： | 2 |
| 6 | Clinical efficacy and cost per quality adjusted life years of pararenal endovascular aortic aneurysm repair compared with open surgical repair显示文摘 | Sherif Sultan Niamh | 2011 | Journal of endovascular therapy:an official journal of the International Society of Endovascular Specialists2011，18，2： | 1 |
| 7 | Expressional alter- ations in functional ultra-conserved non-coding mas in re- sponse to all-trans retinoic acid-induced differentiation in neuroblastoma cells 显示文摘 | Karen M Kenneth B Niamh H | 2013 | BMC Cancer2013，13，： | 1 |
| 8 | Association Between Acute Statin Therapy, Survival, and Improved Functional Outcome After Ischemic Stroke: The North Dublin Population Stroke Study显示文摘 | Danielle Ní Chróinín Elizabeth L. Callaly Joseph Duggan áine Merwick Niamh Hannon órla Sheehan Michael Marnane Gillian Horgan Emma B. Williams Dawn Harris Lorraine Kyne Patricia M.E. McCormack Joan Moroney Tim Grant David Williams Leslie Daly Peter J. Kel | 2011 | Stroke2011，，： | 1 |
| 9 | Reporting intellectual capital in annual reports:evidence from Ireland 显示文摘 | BRENNAN NIAMH | 2001 | Accounting Auditing & Accountability Journal2001，14，4： | 1 |
| 10 | Heart-Type Fatty Acid-Binding Protein Predicts Long-Term Mortality After Acute Coronary Syndrome and Identifies High-Risk Patients Across the Range of Troponin Values显示文摘 | Niamh Kilcullen Karthik Viswanathan Rajiv Das Christine Morrell Amanda Farrin Julian H. Barth Alistair S. Hall | 2007 | Journal of the American College of Cardiology2007，，21： | 1 |
| 11 | Boards of directors and firm performance:is there an expectation gap显示文摘 | NIAMH B | 2006 | Corporate Governance2006，14，6： | 1 |
| 12 | Clinical efficacy and cost per quality - adjusted life years of pararenal endovascular aortic aneurysm re- pair compared with open surgical repair 显示文摘 | Sherif Sultan Niamh Hynes | 2011 | Journal of endovascu- lar therapy:an official journal of the International Society of Endo- vascular Specialists2011，18，2： | 1 |
| 13 | Development of gas chromatography-mass spectrometry (GC-MS) and other rapid screening methods for the analysis of 16 'legal high' cathinone derivatives显示文摘 | Niamh Nic Daeid Kathleen A S Donna Ramsay | 2014 | Sci Justice2014，54，1： | 1 |
| 14 | Intellectual Capital:Current Issues and Policy Implications显示文摘 | Brenda Connell Niamh Brennan | 2000 | Journal of Intellectual Capital2000，1，3： | 1 |
| 15 | miR-107: a Toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes显示文摘 | Niamh H. Foley Luke A. O’Neill | 2012 | Journal of Leukocyte Biology2012，，： | 1 |
| 16 | Endoplasmic Reticulum Stress and Apoptosis Signaling in Human Temporal Lobe Epilepsy显示文摘 | Akitaka Yamamoto Niamh Murphy Clara K | 2006 | J Neuropathol Exp Neurol2006，65，3： | 1 |
| 17 | Characterization of the Drosophila Atlastin Interactome Reveals VCP as a Functionally Related Interactor显示文摘At least 25 genes,many involved in trafficking,localisation or shaping of membrane organelles,have been identified as causative genes for the neurodegenerative disorder hereditary spastic paraplegia(HSP).One of the most commonly mutated HSP genes,atlastin-1, encodes a dynamin-like GTPase that mediates homotypic fusion of endoplasmic reticulum(ER) membranes.However,the molecular mechanisms of atlastin-1-related membrane fusion and axonopathy remain unclear.To better understand its mode of action,we used affinity purification coupled with mass spectrometry to identify protein interactors of atlastin in Drosophila.Analysis of 72 identified proteins revealed that the atlastin interactome contains many proteins involved in protein processing and transport,in addition to proteins with roles in mRNA binding,metabolism and mitochondrial proteins.The highest confidence interactor from mass spectrometry analysis, the ubiquitin-selective AAA-ATPase valosin-containing protein(VCP),was validated as an atlastin-interacting protein,and VCP and atlastin showed overlapping subcellular distributions.Furthermore,VCP acted as a genetic modifier of atlastin:loss of VCP partially suppressed an eye phenotype caused by atlastin overexpression,whereas overexpression of VCP enhanced this phenotype.These interactions between atlastin and VCP suggest a functional relationship between these two proteins,and point to potential shared mechanisms between HSP and other forms of neurodegeneration. | Niamh C.O'Sullivan Nina Drger Cahir J.O'Kane | 2013 | Journal of Genetics and Genomics2013，40，6： | 1 |
| 18 | Mod- eling the effect of glycerol on the moisture sorption behavior of whey protein edible films 显示文摘 | John N Coupland Niamh B Shaw Frank J Monahan | 2000 | Journal of Food Engineering2000，43，1： | 1 |
| 19 | Statin Therapy and Outcome After Ischemic Stroke: Systematic Review and Meta-Analysis of Observational Studies and Randomized Trials显示文摘 | Danielle Ní Chróinín Kjell Asplund Signild ?sberg Elizabeth Callaly Elisa Cuadrado-Godia Exuperio Díez-Tejedor Mario Di Napoli Stefan T. Engelter Karen L. Furie Sotirios Giannopoulos Antonio M. Gotto Niamh Hannon Fredrik Jonsson Moira K. Kapral Joan Martí | 2013 | Stroke2013，，2： | 1 |
| 20 | Successful treatment of massive pulmonary embolism with prolonged catheter-directed thrombolysis显示文摘 | Peter K Niamh C Cliona G | 2006 | Heart Vessels2006，21，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员