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| 1 | Immunolocalization of aquaporin-9 in rat hepatocytes and Leydig cells 显示文摘 | Nihei K Koyama Y Tani T | 2001 | Arch HistolCytol2001，64，1： | 2 |
| 2 | Effects of cyclic intermittent etidronate therapy on coronary artery calcification in patients receiving long-term hemodialysis显示文摘 | Kosaku Nitta Takashi Akiba Koichi Suzuki Keiko Uchida Ryo-Ichiro Watanabe Kazuhiro Majima Takanao Aoki Hiroshi Nihei | 2004 | American Journal of Kidney Diseases2004，，4： | 2 |
| 3 | Randomized controlled study of gemcitabine plus S-1 combination chemotherapy versus gemcitabine for unresectable pancreatic cancer显示文摘 | Kentaro Sudo Takeshi Ishihara Nobuto Hirata Fumiaki Ozawa Tadashi Ohshima Ryosaku Azemoto Kenji Shimura Takeshi Nihei Takayoshi Nishino Akihiko Nakagawa Kazuyoshi Nakamura Taro Hara Motohisa Tada Rintaro Mikata Katsunobu Tawada Osamu Yokosuka So Nakaji Ta | 2014 | Cancer Chemotherapy and Pharmacology2014，，2： | 2 |
| 4 | Mapping of metastasis suppressor genes for prostate cancer by microcell-mediated chromosome transfer显示文摘Aim: To identify the metastasis suppressor genes for prostate cancer. Methods: A copy of human chromosomes was introduced into the highly metastatic Dunning R-3327 rat prostate cancer cells by the use of microcell-mediated chromosome transfer. Relationships between the size of human chromosomes introduced into microcell hybrid clones and the number of lung metastases produced by the clones were analyzed to determine which part of human chromosomes contained the metastasis suppressor gene (s) for prostate cancer. To determine portions of human chromosomes introduced, G-banding chromosomal analysis, fluorescence in situ hybridization analysis, and polymerase chain reaction analysis were performed. Results: Each of microcell hybrid clones containing human chromosomes 7, 8, 10, 11, 12, or 17 showed decreased ability to metastasize to the lung without any loss of ttmaorigenicity. This demonstrates that these human chromosomes contain metastasis suppressor genes for prostate cancer. Spontaneous deletion of portions of human chromosomes was observed in the human chromosome 7, 10, 11, 12, and 17 studies. In the human chromosome 8 study, irradiated microcell-mediated chromosome transfer was performed to enrich chromosomal ann deletions of human chromosome 8. Molecular and cytogenetic analyses of microcell hybrid clones demonstrated that metastasis suppressor genes on human chromosomes were located on 7q21-22, 7q31.2-32, 8p21-12, 10q11-22, 11p13-11.2, 12p11-q13, 12q24-ter, and 17pter-q23. KAI1 and MKK4/SEKI were identified as metastasis suppressor genes from 11p11.2 and 17p12, respectively. Conclusion: This assay system is useful to identify metastasis suppressor gene (s) for prostate cancer. | Tomohiko ICHIKAWA Shigeru HOSOKI Hiroyoshi SUZUKI Koichiro AKAKURA Tatsuo IGARASHI Yuzo FURUYA Mitsuo OSHIMURA Carrie W.RINKER-SCHAEFFER Naoki NIHEI J.Carl BARRETT John T.ISAACS Haruo ITO | 2000 | Asian Journal of Andrology2000，2，3： | 2 |
| 5 | Long-term toxicity after definitive chemoradiotherapy for squamous cell carcinoma of the thoracic esophagus显示文摘 | Ishikura S Nihei K Ohtsu A | 2003 | J Clin Oncol2003，21，： | 1 |
| 6 | Dose-escalation study of thoracic radiotherapy in combination with pemetrexed plus cisplatin followed by pemetrexed consolidation therapy in japanese patients with locally advanced nonsquamous nonsmall-cell lung cancer显示文摘 | Niho S Kubota K Nihei K | 2013 | Clinical Lung Cancer2013，14，1： | 1 |
| 7 | Endoscopic resection of benign breast tumoys;retromammary space approach显示文摘 | Osanai T Nihei Z Ichikaua W | 2002 | Surg Laparosc Endosc Percutan Tech2002，12，6： | 1 |
| 8 | N-methyl-D-aspartate receptor subunit changes are associated with lead-induced deficits of long-term potentiation and spatial learning显示文摘 | Nihei MK Desmond NL McGlothan JL | 2000 | Neuroscience2000，99，2： | 1 |
| 9 | Endoscopic resection of benign breast tumors: retromammary space approach 显示文摘 | Osanai T Nihei Z Lchikawa W | 2002 | Surg Laparosc Endosc Percutan Tech2002，12，： | 1 |
| 10 | Elective nodal irradiation (ENI) in definitive chemoradiotherapy (CRT) for squamous cell carcinoma of the thoracic esophagus显示文摘 | Onozawa M Nihei K Ishikura S | 2009 | Radiother Oncol2009，92，： | 1 |
| 11 | Long-term toxicity after definitive ehemoradiotherapy for squamous cell carcinoma of the thoracic esophagus显示文摘 | Ishikura S Nihei K Ohtsu A | 2003 | J Clin Oncol2003，21，14： | 1 |
| 12 | Molecular design of antibrowning agents : antioxidative tyrosinase inhibitors 显示文摘 | Kubo I Chen Q X Nihei K | 2003 | Food Chem2003，，81： | 1 |
| 13 | Development of a new high-frequency, high-peak current power source for high constricted arc formation显示文摘 | ONUKI J YOSHIAAY NIHEI M | 2002 | Japanese Journal of Applied Physics2002，41，9： | 1 |
| 14 | Identification of oxidation product of arbutin in rnushroomtyrosinase assay system 显示文摘 | NIHEI K KUBO I | 2003 | Bioorganic & Medicinal Chemi- stry Letters2003，13，： | 1 |
| 15 | Bulk periodically poled MgO-LiNbO3 by corona discharge method显示文摘 | Nihei Y | 1996 | Applied Physics Letters1996，69，： | 1 |
| 16 | Fixed-point observation of Oncomelania nosophora in Kofu Basin-establishment of monitor- ing system of schistosomiasis japonica in Japan 显示文摘 | Nihei N Kajihare N Kirinoki M | 2003 | Parasitol Int2003，52，4： | 1 |
| 17 | Advantages of Inductively Cou- pled Plasma-Assisted Sputtering for Preparation of Stoichiomctric VO2 Films with Metal-Insulator Transition 显示文摘 | Nihei Y Sasakawa Y Okimura K | 2008 | Thin Solid Films2008，516，11： | 1 |
| 18 | Two-dimensional Contact Pressure Distribution of a Radial Tire显示文摘 | Akasaka T Katok M Nihei S | 1990 | Tire Science and Technology1990，18，2： | 1 |
| 19 | Renal angiomyolipoma in Japanese tuberous sclerosis patients显示文摘 | Kitano Y Honna T Nihei K | 2004 | J Pediatr Surg2004，39，12： | 1 |
| 20 | KOsseointegration of a hydroxyapatite coated multilayered mesh stem显示文摘 | Kusakabe H SakamakiT Nihei | | 0，，： | 1 |
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