|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Insulin glargine versus NPH insulin therapy in Asian Type 2 diabetes patients显示文摘 | Pan, CY Sinnassamy, P Chung, KD Kim, KW | 2007 | 中国生物学文摘2007，21，11： | 17 |
| 2 | Celecoxib-related gastroduodenal ulcer and cardiovascular events in a randomized trial for gastric cancer prevention显示文摘AIM: To evaluate the long-term risk of gastroduodenal ulcer and cardiovascular events induced by celecoxib in a population-based, randomized, double-blind, placebo-controlled study.METHODS: From 2004 to 2006, a total of 1024 Chinese patients (aged 35 to 64 years) with severe chronic atrophic gastritis, intestinal metaplasia or dysplasia were randomly assigned to receive 200 mg of celecoxib twice daily or placebo in Linqu County (Shandong Province, China), a high-risk area of gastric cancer. All gastroduodenal ulcer and cardiovascular events occurred were recorded and the patients were followed up for 1.5 years after treatment. At the end of the trial, a systematic interview survey about other adverse events was conducted. RESULTS: Gastroduodenal ulcer was detected in 19 of 463 (3.72%) patients who received celecoxib and 17 of 473 (3.31%) patients who received placebo, respectively (odds ratio = 1.13, 95% CI = 0.58-2.19). Cardiovascular (CV) events occurred in 4 patients who received celecoxib and in 5 patients who received placebo, respectively. Compared with those who received placebo, patients who received celecoxib had no signif icant increase in occurrence of CV events (hazard ratio = 0.84, 95% CI = 0.23-3.15). Among the adverse events acquired by interview survey, only the frequency of bloating was signif icantly higher in patients treated with celecoxib than in those treated with placebo. CONCLUSION: Treatment of gastric cancer with celecoxib is not associated with increased risk of gastroduodenal ulcer and cardiovascular events. | Guo-Shuang Feng Jun-Ling Ma Benjamin CY Wong Lian Zhang Wei-Dong Liu Kai-Feng Pan Lin Shen Xiao-Dong Zhang Jie Li Harry HX Xia Ji-You Li Shiu Kum Lam Wei-Cheng You | 2008 | World Journal of Gastroenterology2008，14，28： | 4 |
| 3 | Thymidine kinase gene mutation leads to reduced virulence of pseudorabies virus显示文摘To explore correlation between the tk gene structure of pseudorabies virus (PRV) and its virulence, to study the effect of the gene mutation on PRV biological properties, and to investigate mechinism of reduced virulence, thymidine kinase (TK)-deficient mutant of pseudorabies virus strain Hubei (PRV HB) was isolated by selection for resistance to 5-bromodeoxyuridine. The tk genes of PRV HB and its TK mutant were cloned and sequenced. 1587 base pairs of the tk gene and flanking regions of wild-type (wt) virus were sequenced, which included an open reading frame (ORF) of 1098 bp encoding a protein of 366 amino acids. The ORF contained two 137-bp repeated sequences, which were connected by an adenosine. 1458 bp of the tk and flanking regions of TK- mutant were sequenced. Analysis of the tk gene sequence of TK mutant indicated that one of 137 bp repeated sequence and the connecting adenosine in the tk gene of the wt virus was deleted and a repeated sequence of 8 nucleotides (GCGCGCC) was inserted. All | Pan, ZS Zhang, CY Ding, JH Min, P | 2001 | Chinese Science Bulletin2001，46，23： | 2 |
| 4 | Biomechanical ana- lysis of alveolar bone stress around implants with different thread designs and pitches in the mandi- bular molar area显示文摘 | Lan TH Du JK Pan CY | 2012 | Clin Oral Investig2012，16，2： | 1 |
| 5 | Cigarette smoking and the risk of colorectal cancer: a meta-analysis of prospective cohort studies 显示文摘 | Tsoi KK Pan CY Wu WK | 2009 | Clin Gastroenterol Hepatol2009，7，6： | 1 |
| 6 | Efficacy of acarbose in Chiness subjects with impaired glucose tolerance 显示文摘 | Pan CY Gao Y Chen JW | 2003 | Diabets Resclin Pract2003，61，3： | 1 |
| 7 | Differential expression of carotenoid-related genes determines diversified carotenoid coloration in floral tissues of Oncidium cultivars 显示文摘 | CHIOU CY PAN HA CHUANG YN | 2010 | Planta2010，232，： | 1 |
| 8 | Opening of the blood-brain barrier by low-frequency(28-kHz)ultrasound:a novel pinhole-assisted mechanical scanning device显示文摘 | Liu HL Pan CH Ting CY | | 0，，： | 1 |
| 9 | The relationship between coronary artery disease and abnormal glucose regulation in China:The China Heart Survey显示文摘 | Hu DY Pan CY Yu JM | 2006 | Eur Heart J2006，27，： | 1 |
| 10 | Biomechanical analysis of alveolar bone stress around implants with different thread designs and pitches in the mandibular molar area显示文摘 | Lan TH Du JK Pan CY | | 0，，02： | 1 |
| 11 | Stable and high energy generation by a strain of Bacillus subtilis in a microbial fuel cell 显示文摘 | Nimje VR Chen CY Chert CC Jean JS Reddy AS Fan CW Pan KY Liu HT Chen JL | 2009 | JPower Sourc2009，190，2： | 1 |
| 12 | Study of the prevalence of diabetes mellitus in adults in the Shougang corporation in Beijing显示文摘 | Pan CY Lu JM Tian H | 1996 | Diabet Med1996，13，： | 1 |
| 13 | Expression ofβ-catenin in rheumatoid arthritis Fibroblastlike synoviocytes显示文摘 | Xiao CY Pan YF Guo XH | 2011 | Scand J Rheumatol2011，40，1： | 1 |
| 14 | Evaluation of potential antidepres-sant-like activity of chalcone-1203 in various murine experimental de-pressant models显示文摘 | Guan LP Tang LM Pan CY | 2014 | Neurochem Res2014，39，2： | 1 |
| 15 | The teaching - learning aproaeh and critical thinking development: a qualitative exploration of taiwanese nursing students显示文摘 | Lin CC Han CY Pan IJ | 2015 | Journal of Professional Nursing2015，31，2： | 1 |
| 16 | Expression of beta-catenin in rheumatoid arthritis fibroblast-like synoviocytes显示文摘 | Xiao CY Pan YF Guo XH | 2011 | Stand JRheumatol2011，40，1： | 1 |
| 17 | Effect of mefformin on patients with impaired glucose tolerance显示文摘 | Li CL Pan CY Lu JM | 1999 | Diabet Med1999，16，6： | 1 |
| 18 | YC-1 inhibits neointima formation in balloon- injured rat carotid through suppression of expressions and activities of matrix metalloproteinases 2 and 9 显示文摘 | Liu YN Pan SL Peng CY | 2006 | Pharmacol Exp Ther2006，316，1： | 1 |
| 19 | Efficacy and safety of saxagliptin indrug-nave Asian patients with type 2 diabetes mellitus:a random-ized controlled trial显示文摘 | Pan CY Yang W Tou C | 2012 | Diabetes Metab Res Rev2012，28，3： | 1 |
| 20 | Management of Chinese patients with type 2 diabetes, 1998 -2006: the Diabcare- China Surveys 显示文摘 | Pan CY Yang WY Jia WP | 2009 | Curt Med Res Opin2009，25，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员