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| 1 | Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response显示文摘AIM: To investigate the co-incidence of apoptosis, autophagy, and unfolded protein response(UPR) in hepatitis B(HBV) and C(HCV) infected hepatocytes.METHODS: We performed immunofluorescence confocal microscopy on 10 liver biopsies from HBV and HCV patients and tissue microarrays of HBV positive liver samples. We used specific antibodies for LC3β, cleaved caspase-3, BIP(GRP78), and XBP1 to detect autophagy, apoptosis and UPR, respectively. AntiHCV NS3 and anti-HBs antibodies were also used to confirm infection. We performed triple blind counting of events to determine the co-incidence of autophagy(LC3β punctuate), apoptosis(cleaved caspase-3), and unfolded protein response(GRP78) with HBV and HCV infection in hepatocytes. All statistical analyses were performed using SPSS software for Windows(Version 16 SPSS Inc, Chicago, IL, United States). P-values < 0.05 were considered statistically significant. Statistical analyses were performed with Mann-Whitney test to compare incidence rates for autophagy, apoptosis, and UPR in HBV- and HCV-infected cells and adjacent noninfected cells.RESULTS: Our results showed that infection of hepatocytes with either HBV and HCV induces significant increase(P < 0.001) in apoptosis(cleavage of caspase-3), autophagy(LC3β punctate), and UPR(increase in GRP78 expression) in the HCV- and HBVinfected cells, as compared to non-infected cells of the same biopsy sections. Our tissue microarray immunohistochemical expression analysis of LC3β in HBV^(Neg) and HBV^(Pos) revealed that majority of HBVinfected hepatocytes display strong positive stainingfor LC3β. Interestingly, although XBP splicing in HBVinfected cells was significantly higher(P < 0.05), our analyses show a slight increase of XBP splicing was in HCV-infected cells(P > 0.05). Furthermore, our evaluation of patients with HBV and HCV infection based on stage and grade of the liver diseases revealed no correlation between these pathological findings and induction of apoptosis, autophagy, and UPR.CONCLUSION: The results of this study indicate that HCV and HBV infection activates apoptosis, autophagy and UPR, but slightly differently by each virus. Further studies are warranted to elucidate the interconnections between these pathways in relation to pathology of HCV and HBV in the liver tissue. | Behzad Yeganeh Adel Rezaei Moghadam Javad Alizadeh Emilia Wiechec Seyed Moayed Alavian Mohammad Hashemi Bita Geramizadeh Afshin Samali Kamran Bagheri Lankarani Martin Post Payam Peymani Kevin M Coombs Saeid Ghavami | 2015 | World Journal of Gastroenterology2015，21，47： | 13 |
| 2 | Fatal motorcycle accidents in Fars Province, Iran: a com- munity-based survey显示文摘ObjectiveTo 在 Fars 省识别摩托车事故的牺牲品的主要特征, Iran.MethodsThis 代表性的学习在从 2009 年 3 月在伊朗有所有 31 个省的第四张最大的人口到 2010 年 6 月的 Fars 省被进行。我们从所有 542 的 includeddata 由于机动车辆事故记录了死亡的盒子。数据从由人口统计、事故相关的信息组成的法庭的药登记被记录。人口统计的信息由名字,年龄,性别,致命的牺牲品(摩托车驱动程序对旅客) 的地位和 2 345 尸体从法庭的药档案记录的教育 level.ResultsOf 组成了,(23.1%) 542 作为机动车辆事故给了死亡的原因。这些牺牲品的吝啬的年龄是(31.4 ±16.5 ) 年,和男性到女比率是 28。头损害是在这些牺牲品的死亡的最普通的原因,并且总的来说,他们趋于有教育的底层。摩托车事故经常包含了更年轻的年龄组(15-35 年) ,并且与一顶头盔的弃权联系的头损伤是 death.ConclusionsHead 损害的最普通的原因在在我们学习了的省的牺牲品之中是经常的。这种状况可能与 victims’ 有关关于交通法律与他们的弱实施一起导致加速和这些法律的不顾的低社会经济的地位和很少教育。 | Seyed Taghi Heydari Najmeh Maharlouei Aft Foroutan Yaser Sarikhani Fariborz Ghaffarpasand Arya Hedjazi Mohammad Zarenezhad Ghasem Moafian Mohammad Reza Aghabeigi Payam Peymani Seyed Mehdi Ahmadi Maryam Dehghankhalili Hassan Joulaei Kamran B. Lankarani | 2012 | Chinese Journal of Traumatology2012，15，4： | 6 |
| 3 | Epidemiological characteristics of fatal pedestrian ac- cidents in Fars Province of Iran: a community-based survey显示文摘ObjectiveTo 决定在 Iran.MethodsThis 代表性的学习的 Fars 省的致命的步行事故的流行病学的特征从 2009 年 3 月在一个 29 月的时期期间在伊朗的 Fars 省被进行到 2011 年 7 月。数据从 Fars 法庭的药登记。在 4 923 记录道路交通事故死亡, 971 死亡由于步行事故。人口统计、事故相关的信息被社会科学统计套装软体版本 11.5 分析。不到 0.05 被认为死者的 significant.ResultsThe 平均数年龄的 P 价值是(47.2 ±26.2 ) 年,从 6 个月到 103 岁。男性们说明了 69.8% 所有死亡。致命的事故在 9 月是很普通的;56.1% 致命的损害发生在 intracity 道路上并且 33.1% 在 extracity 道路上。致命的头损害在 60.54% 盒子中是在场的。损害地点的评估和死亡的原因发现他们显著地与年龄被联系,在损害和死亡之间的间隔。而且,道路的类型在 mortality.ConclusionAlthough 起了一个重要作用损伤病人的临床的管理在最近的十年在我们的国家被改进了,减少损害的负担在损伤系统组织之中需要协作。 | Payam Peymani Seyed Taghi Heydari Amin Hoseinzadeh Yaser Safikhani Arya Hedjazi Mohammad Zarenezhad Ghasem Moafian Mohammad Reza Aghabeigi Najmeh Maharlouei All Foroutan Seyed Mehdi Ahmadi FariborzGhaffarpasand Hassan Joulaei Kamran B Lankarani | 2012 | Chinese Journal of Traumatology2012，15，5： | 5 |
| 4 | An accurate empirical correlation for predicting natural gas viscosity显示文摘Natural gas viscosity is an important parameter in many gas and petroleum engineering calculations.This study presents a new empirical model for quickly calculating the natural gas viscosity.The model was derived from 4089 experimental viscosity data with varieties ranging from 0.01 to 21,and 1 to 3 of pseudo reduced pressure and temperature,respectively.The accuracy of this new empirical correlation has been compared with commonly used empirical models,including Lee et al.,Heidaryan et al.,Carr et al.,and Adel Elsharkawy correlations.The comparison indicates that this new empirical model can predict viscosity of natural gas with average absolute relative deviation percentage AARD (%) of 2.173. | Ehsan Sanjari Ebrahim Nemati Lay Mohammad Peymani | 2011 | Journal of Natural Gas Chemistry2011，20，6： | 4 |
| 5 | The influence of peroxisome proliferator-activated receptor γ 1 during differentiation of mouse embryonic stem cells to neural cells显示文摘 | Ali Ghoochani Khadijeh Shabani Maryam Peymani Kamran Ghaedi Fereshteh Karamali Khadijeh Karbalaei Somayeh Tanhaie Ahmad Salamian Abolghasem Esmaeili Sadegh Valian-Borujeni Mehrdad Hashemi Mohammad Hossein Nasr-Esfahani Hossein Baharvand | 2011 | Differentiation2011，，1： | 2 |
| 6 | The influence of peroxisome proliferator-activated receptor γ1 during differentiation of mouse embryonic stem cells to neural cells 显示文摘 | Ghoochani A Shabani K Peymani M | 2012 | Differentiation2012，83，1： | 1 |
| 7 | High prevalence of metallo- beta-lactamase-producing Acinetobacter baumannii in a teaching hospi- tal in Tabriz,Iran显示文摘 | Peymani A Nahaei MR Farajnia S | 2011 | Jpn J Infect Dis2011，64，1： | 1 |
| 8 | Quantum dot:magic nanoparticle for imaging,detection and targeting显示文摘 | Ghasemi Y Peymani P Afifi S | | 0，，02： | 1 |
| 9 | Characterisation and clonal dissemination of OXA-23-producing Acinetobacter baumannii in Tabriz,northwest Iran显示文摘 | Peymani A Higgins PG Nahaei M | 2012 | International Journal of Antimicrobial Agents2012，39，6： | 1 |
| 10 | Quantum Dot:Magic Nanoparticle for Imaging,Detection and Targeting显示文摘 | CHASEMI Y PEYMANI P AFWI S | 2009 | Acta Biomed2009，80，2： | 1 |
| 11 | RNA sequencing role and application in clinical diagnostic显示文摘Although whole-exome sequencing and whole-genome sequencing has tremendously improved our understanding of the genetic etiology of human disorders,about half of the patients still do not receive a molecular diagnosis.The high fraction of variants with uncertain significance and the challenges of interpretation of noncoding variants have urged scientists to implement RNA sequencing(RNA-seq)in the diagnostic approach as a high throughput assay to complement genomic data with functional evidence.RNA-seq data can be used to identify aberrantly spliced genes,detect allele-specific expression,and identify gene expression outliers.Amongst eight studies utilizing RNA-seq,a mean diagnostic uplift of 15%has been reported.Here,we provide an overview of how RNA-seq has been implemented to aid in identifying the causal variants of Mendelian disorders. | Fatemeh Peymani Aiman Farzeen Holger Prokisch | 2022 | Pediatric Investigation2022，6，1： | 1 |
| 12 | High prevalence of metallo-be-ta-lactamase-producing acinetobacter baumannii in a teaching hospitalin Tabriz显示文摘 | Peymani A Nahaei M Farajnia S | 2011 | Jpn J Infect Dis2011，64，1： | 1 |
| 13 | Characterisation and clonal dissemination of OXA --23 -- producing Acinetobacter baumannii in Tabriz, northwest Iran显示文摘 | PEYMANI A HIGGINS P G NAHAEI M R | 2012 | Int J Antimicrob Agents2012，39，6： | 1 |
| 14 | Quantum dot:magic nanoparticle for imaging,detection and targeting显示文摘 | Ghasemi Y Peymani P Afifi S | | 0，，2： | 1 |
| 15 | Path following of underwater robots using Lagrange multipliers 显示文摘 | PEYMANI E FOSSEN T I | 2015 | Robotics and Autonomous Systems2015，67，： | 1 |
| 16 | High prevalence of metallo-I~-lactamase-producing Acinetobacter baumannii in a teaching hospital in Tahriz, Iran 显示文摘 | Peymani A Nahaei MR Farajnia S | 2011 | Jpn J Infect Dis2011，64，1： | 1 |
| 17 | High prevalence of metallo-beta-lactamase-producing Acinetobacter baumannii in a teaching hospital in Tabriz,Iran显示文摘 | Peymani A Nahaei MR Farajnia S | 2011 | Jpn J Infect Dis2011，64，： | 1 |
| 18 | Path following of underwater robots using Lagrange multipliers显示文摘 | PEYMANI E FOSSEN T | 2015 | Robotics and Autonomous Systems2015，67，： | 1 |
| 19 | Burden of traffic accidents among pedestrians of Fars province, southern Iran; estimate of years of life lost in a sample of Iranian population from 2009 to 2013显示文摘PurposeTraffic 损害在死亡和世界范围的病态的领先的原因之中。行人在道路用户之中被看作了一个高风险的组,特别在中间收入或低收入的社区。这研究试图在 Fars 决定行人死亡的负担,用 approach.MethodsThe 数据在这研究使用了的丧生的(YLL ) 的年的伊朗的南部的省在步行交通事故上从 Fars 法庭的药组织数据库被检索。从 2009 ~ 2013 的 YLL 用世界健康组织介绍的方法被估计。行人死亡的一些流行病学的特征被 SPSS.ResultsAlthough YLL 在 1000 个男行人之中分析在 2013 在 2009 ~ 1.5 从 2.5 减少了,它在一样的时期期间在 1000 女性之中从 0.9 ~ 2.1 增加了。死亡的更高的比例在女性,文盲,和结婚行人被发现(p ? | Yaser Sarikhani Seyed Taghi Heydari Saeed Gholamzadeh Maryam Mazloom Payam Peymani Kamran Bagheri Lankarani Ahmad Kalateh Sadati Reza Tabrizi Maryam Akbari | 2017 | Chinese Journal of Traumatology2017，20，5： | 1 |
| 20 | High prevalence of metallo-beta-Iactamase-producing Acinetobacter baumannii in a teaching hospital in Tabriz , Iran 显示文摘 | Peymani A Nahaei MR Farajnia Sv er al | 2011 | Ipn J Infect Dis2011，64，1： | 1 |
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