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| 1 | Nuclear Aurora kinase A switches m^(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4显示文摘Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression,yet how this process is regulated by oncogenic signal remains largely unknown.Here,we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m^(6)A reader YTHDC1 in lung cancer.Nuclear translocation of AURKA is a prerequisite for RNA aberrant splicing,specifically triggering RBM4 splicing from the full isoform(RBM4-FL)to the short isoform(RBM4-S)in a kinase-independent manner. | SiSi Li YangFan Qi JiaChuan Yu YuChao Hao Bin He MengJuan Zhang ZhenWei Dai TongHui Jiang SuYi Li Fang Huang Ning Chen Jing Wang MengYing Yang DaPeng Liang Fan An JinYao Zhao WenJun Fan YuJia Pan ZiQian Deng YuanYuan Luo Tao Guo Fei Peng ZhiJie Hou ChunLi Wang FeiMeng Zheng LingZhi Xu Jie Xu QingPing Wen BiLian Jin Yang Wang Quentin Liu | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 4 |
| 2 | Reduction-induced interface reconstruction to fabricate MoNi_(4) - based hollow nanorods for hydrazine oxidation assisted energysaving hydrogen production in seawater显示文摘Seawater electrolysis could address the water scarcity issue and realize the grid-scale production of carbon-neutral hydrogen,while facing the challenge of high energy consumption and chloride corrosion.Thermodynamically more favorable hydrazine oxidation reaction(HzOR)assisted water electrolysis is efficiency for energy-saving and chlorine-free hydrogen production.Herein,the MoNi alloys supported on MoO_(2) nanorods with enlarged hollow diameter on Ni foam(MoNi@NF)are synthesized,which is constructed by limiting the outward diffusion of Ni via annealing and thermal reduction of NiMoO_(4) nanorods.When coupling HzOR and hydrogen evolution reaction(HER)by employing MoNi@NF as both anode and cathode in two-electrode seawater system,a low cell voltage of 0.54 V is required to achieve 1,000 mA·cm^(−2) and with long-term durability for 100 h to keep above 100 mA·cm^(−2) and nearly 100%Faradaic efficiency.It can save 2.94 W·h to generate per liter H_(2) relative to alkaline seawater electrolysis with 37%lower energy equivalent input. | Lili Guo Qingping Yu Xuejun Zhai Jingqi Chi Tong Cui Yu Zhang Jianping Lai Lei Wang | 2022 | Nano Research2022，15，10： | 2 |
| 3 | Analysis and Research of Web Chinese Retrieval system Based Lunece显示文摘 | Liu chun Guo Qingping | 2009 | Computer society2009，，12： | 1 |
| 4 | Immortalized mouse dental papilla mesenchymal cells preserve odontoblastic phenotype and respond to bone morphogenetic protein 2显示文摘 | Feng Wang Li-An Wu Wentong Li Yuan Yang Feng Guo Qingping Gao Hui-Hsiu Chuang Lisa Shoff Wei Wang Shuo Chen | 2013 | In Vitro Cellular & Developmental Biology - Animal2013，，： | 1 |
| 5 | Concurrent communication and granularity assessment for a transputer-based multiprocessor system显示文摘 | Guo Qingping Yakup Paker | 1990 | Journal of Computer Systems Science & Engineering1990，5，1： | 1 |
| 6 | Computer Methods in Applied Mechanics and Engineering显示文摘 | Ping Lin Qingping Guo Xianqiao Chen | 2003 | 5 (192): 2555~25642003，5，192： | 1 |
| 7 | Rapid dissociation and on-site saturation evaluation of methane hydrate sediment samples for natural gas hydrate exploitation显示文摘Natural gas hydrate is a kind of clean energy with huge reserves,and the saturation(volume percentage of hydrate in pore space of sediments)is the key parameter for determining whether the reservoir is worthy of exploitation.In this work,rapid hydrate dissociation by the combination of heat injection and NaCl inhibitor addition was studied,and an on-site evaluation method for hydrate saturation in sediment samples was proposed by using a core sampler to transfer hydrate samples under pressure.The results showed that the average gas production rate per unit volume was increased significantly to reach 7.22 L/Lr$min-1 by the injection of NaCl aqueous solution with 50.9C,which was attributed to the increase of the chemical potential to further accelerate the rate of hydrate dissociation in the presence of NaCl.Furthermore,for the measurement of methane hydrate samples saturation with a volume of 673 cm3(which contained 1.4 mol hydrates with the saturation of 58%),hydrate saturation could be accurately achieved within 30 min with a relative error lower than 11.7%This work may provide new thoughts for on-site saturation evaluation and rapid dissociation of hydrate samples during natural gas hydrate exploitation. | Shuanshi Fan Kai Guo Yanhong Wang Xuemei Lang Na Wei Qingping Li | 2021 | Petroleum2021，7，4： | 1 |
| 8 | Abnormal expression of matrix metalloproteinase-9 (MMP9)correlates with clinical course in Chinese patients with endometrialcancer显示文摘 | Fang Yu Qingping Jiang Ying Zhou Zhen Yang Xiaoli Yu Hao Wang Zhen Liu Lijing Wang Weiyi Fang Suiqun Guo | 2012 | Disease Markers2012，，5： | 1 |
| 9 | Adaptive Dynamic Parallel Delaunay Mesh Generation with Minimal Communication Load显示文摘 | YUAN Youwei GUO Qingping PENG Zhaoyi | 2006 | Chinese Journal of Electronics2006，15，3： | 0 |
| 10 | Entanglement Protection of Two-Qubit System in Non-Markovian Reservoir via Weak Measurement and Weak Measurement Reversal显示文摘The protection schemes of the entanglement in the system of two entangled atoms from nonMarkovian reservoirs via previous Weak measurement(pre-WM) and posterior Weak measurement reversal(post-WMR) are investigated. We firstly compare the effects of combination applying of pre-WM and post-WMR(scheme 1) and twice Weak measurements(WMs)(scheme2) in the condition of different initial entangled states.The analysis indicates that the protection performance of scheme 1 is much better than that of scheme 2. The scheme1 was utilized when the system of two entangled atoms suffers from the independent reservoirs. The numerical results show that the combination of pre-WM and postWMR can effectively enhance entanglement and shorten the time of Entanglement sudden death(ESD) in nonMakovain environment. We have found the optimum of WM strengthens is drastically related to the initial entangled state. | GUO Xiuli ZHANG Yanliang KANG Guodong ZHOU Qingping | 2019 | Chinese Journal of Electronics2019，28，3： | 0 |
| 11 | High-performance supercapacitors based on Ni_(2)P@CNT nanocomposites prepared using an ultrafast microwave approach显示文摘We present a one-step route for the preparation of nickel phosphide/carbon nanotube(Ni_(2)P@CNT)nanocomposites for supercapacitor applications using a facile,ultrafast(90 s)microwave-based approach.Ni2P nanoparticles could grow uniformly on the surface of CNTs under the optimized reaction conditions,namely,a feeding ratio of 30:50:25 for CNT,Ni(NO_(3))_(2)-6H_(2)O,and red phosphorus and a microwave power of 1000 W for 90 s.Our study demonstrated that the single-step microwave synthesis process for creating metal phosphide nanoparticles was faster and simpler than all the other existing methods.Electrochemical results showed that the specific capacitance of the optimal Ni2P@CNT-nanocomposite electrode displayed a high specific capacitance of 854 F•g^(-1) at 1 A•g^(-1) and a superior capacitance retention of 84% after 5000 cycles at 10 Ag^(-1).Finally,an asymmetric supercapacitor was assembled using the nanocomposite with activated carbon as one electrode(Ni_(2)P@CNT//AC),which showed a remarkable energy density of 33.5 W•h•kg^(-1) and a power density of 387.5 W·kg^(-1).This work will pave the way for the microwave synthesis of other transition metal phosphide materials for use in energy storage systems. | Yunrui Tian Haishun Du Shatila Sarwar Wenjie Dong Yayun Zheng Shumin Wang Qingping Guo Jujie Luo Xinyu Zhang | 2021 | Frontiers of Chemical Science and Engineering2021，15，4： | 0 |
| 12 | 4D printing of core-shell hydrogel capsules for smart controlled drug release显示文摘Personalized drugs,as well as disease-specific and condition-dependent drug release,have been highly desired in drug delivery systems for effective and safe therapies.Four-dimensional(4 D)printing,as a newly emerging technique to develop drug capsules,displays unique advantages that can autonomously control drug release according to the actual physiological circumstances.Herein,core-shell structured hydrogel capsules were developed using a multimaterial extrusion-based 4 D printing method,which consists of a model drug as the core and UV cross-linked poly(N-isopropylacrylamide)(PNIPAM)hydrogel as the shell.Owing to the lower critical solution temperature(LCST)-induced shrinking/swelling properties,the prepared PNIPAM hydrogel capsules showed temperature-responsive drug release along with the topography changes in the cross-linked PNIPAM network.The in vitro drug release test confirmed that the PNIPAM hydrogel capsules can autonomously control their drug release behaviors according to changes in ambient temperature.Moreover,the increased shell thickness of these capsules causes an obvious reduction in drug release rate,distinctly indicating that the drug release behavior can be well adjusted by setting the shell thickness of the capsules.The proposed 4 D printing strategy pioneers the paradigm of smart drug release by showing great potential in the smart controlled release of drugs and macromolecular active agents. | Shuo Zu Zhihui Zhang Qingping Liu Zhenguo Wang Zhengyi Song Yunting Guo Yuanzhu Xin Shuang Zhang | 2022 | Bio-Design and Manufacturing2022，5，2： | 0 |
| 13 | Conceptualizing and Measuring Global Justice:Theories,Concepts,Principles and Indicators显示文摘The paper focuses on the conceptualization and measurement of global justice and discusses theories,concepts,evaluative principles,and methodologies related to the study of global justice.In this paper,we seek to clarify how to conceptualize global justice,how conceptual indicators can be selected and justified by theories,and how those indicators can be conceptually consistent with the concept of global justice.Global justice is a broad concept that is composed of multi-level and multidimensional aspects belonging to both normative and empirical realities.A coherent and integrated theoretical framework that covers the normative basis and various empirical dimensions is therefore much needed in order to address some of the basic and important questions under study.The paper seeks to synthesize the multiple theories and conceptions of global justice that exist in the academic discourse and literature into three main theoretical approaches to global justice-rights based,good based,and virtue based.These three approaches are a good sample of and reflect well the strengths of the different theoretical,intellectual and cultural traditions at play in the study of global justice.From this perspective,the synthesis of the three approaches is meant to provide us with a coherent theoretical framework that serves as the normative basis and justifies the selection of indicators for measurement. | Sujian Guo Xi Lin Jean-Marc Coicaud Su Gu Yanfeng Gu Qingping Liu Xuan Qin Guodong Sun Zhongyuan Wang Chunman Zhang | 2019 | Fudan Journal of the Humanities and Social Sciences2019，12，4： | 0 |
| 14 | Physical characteristics of high concentrated gas hydrate reservoir in the Shenhu production test area,South China Sea显示文摘High concentrated and heterogeneous distribution of gas hydrates have been identified in the gas hydrate production test region in the Shenhu area,South China Sea.The gas hydrate-bearing sediments with high saturation locate at two ridges of submarine canyon with different thickness and saturations just above the bottom simulating reflection.The crossplots of gamma ray,acoustic impedance(P-impedance)and porosity at four sites show that the sediments can be divided into the upper and lower layers at different depths,indicating different geotechnical reservoir properties.Therefore,the depositional environments and physical properties at two ridges are analyzed and compared to show the different characteristics of hydrate reservoir.High porosity,high P-wave velocity,and coarse grain size indicate better reservoir quality and higher energy depositional environment for gas hydrate at Sites W18 and W19 than those at Sites W11 and W17.Our interpretation is that the base of canyon deposits at Sites W18 and W19 characterized by upward-coarsening units may be turbidity sand layers,thus significantly improving the reservoir quality with increasing gas hydrate saturation.The shelf and slope sliding deposits compose of the fine-grained sediments at Sites W11 and W17.The gas hydrate production test sites were conducted at the ridge of W11 and W17,mainly because of the thicker and larger area of gas hydrate-bearing reservoirs than those at Sites W18 and W19.All the results provide useful insights for assessing reservoir quality in the Shenhu area. | Jiapeng JIN Xiujuan WANG Zhenyu ZHU Pibo SU Lixia LI Qingping LI Yiqun GUO Jin QIAN Zhendong LUAN Jilin ZHOU | 2023 | Journal of Oceanology and Limnology2023，41，2： | 0 |
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