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| 1 | Telomeres,telomerase and colorectal cancer显示文摘Colorectal cancer(CRC)is the third most common cancer worldwide and,despite improved treatments,is still an important cause of cancer-related deaths.CRC encompasses a complex of diseases arising from a multistep process of genetic and epigenetic events.Besides heterogeneity in the molecular and biological features of CRC,chromosomal instability is a hallmark of cancer and cancer cells may also circumvent replicative senescence and acquire the ability to sustain unlimited proliferation.Telomere/telomerase interplay is an important mechanism involved in both genomic stability and cellular replicative potential,and its dysfunction plays a key role in the oncogenetic process.The erosion of telomeres,mainly because of cell proliferation,may be accelerated by specific alterations in the genes involved in CRC,such as APC and MSH2.Although there is general agreement that the shortening of telomeres plays a role in the early steps of CRC carcinogenesis by promoting chromosomal instability,the prognostic role of telomere length in CRC is still under debate.The activation of telomerase reverse transcriptase(TERT),the catalytic component of the telomerase complex,allows cancer cells to grow indefinitely by maintaining the length of the telomeres,thus favouring tumour formation/progression.Several studies indicate that TERT increases with disease progression,and most studies suggest that telomerase is a useful prognostic factor.Plasma TERT mRNA may also be a promising marker for the minimally invasive monitoring of disease progression and response to therapy. | Roberta Bertorelle Enrica Rampazzo Salvatore Pucciarelli Donato Nitti Anita De Rossi | 2014 | World Journal of Gastroenterology2014，20，8： | 5 |
| 2 | Compound and Digenic Heterozygosity Contributes to Arrhythmogenic Right Ventricular Cardiomyopathy显示文摘 | Tianhong Xu Zhao Yang Matteo Vatta Alessandra Rampazzo Giorgia Beffagna Kalliopi Pillichou Steven E. Scherer Jeffrey Saffitz Joshua Kravitz Wojciech Zareba Gian Antonio Danieli Alessandra Lorenzon Andrea Nava Barbara Bauce Gaetano Thiene Cristina Basso Hu | 2010 | Journal of the American College of Cardiology2010，，6： | 2 |
| 3 | Telomere-Specific Reverse Transcriptase (hTERT) and Cell-free RNA in Plasma as Predictors of Pathologic Tumor Response in Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy显示文摘 | Salvatore Pucciarelli Enrica Rampazzo Marta Briarava Isacco Maretto Marco Agostini Maura Digito Sonia Keppel Maria Friso Sara Lonardi Antonino Paoli Claudia Mescoli Donato Nitti Anita Rossi | 2012 | Annals of Surgical Oncology2012，，9： | 2 |
| 4 | Temporal variability and effect of environmental variables on airborne bacterial communities in an urban area of Northern Italy显示文摘 | Valentina Bertolini Isabella Gandolfi Roberto Ambrosini Giuseppina Bestetti Elena Innocente Giancarlo Rampazzo Andrea Franzetti | 2013 | Applied Microbiology and Biotechnology2013，，14： | 2 |
| 5 | Response of Brazilian maize hybrids from different eras to changes in plant density显示文摘 | Sangoi L Gracietti M A Rampazzo C | 2002 | Field Crops Research2002，79，1： | 1 |
| 6 | Changes in chemistry and mineralogy of forest soils by acid rain显示文摘 | Rampazzo N Blum W E H | 1992 | Water Air and Soil Pollution1992，61，34： | 1 |
| 7 | Mutation in human desmoplakin domain binding to plakoglobin causes a dominant form of arrhythmogenic right ventricular cardiomyopathy 显示文摘 | Rampazzo A Nava A Malacrida S | 2002 | Am J Hum Genet2002，71，5： | 1 |
| 8 | Current collapse and high-electric-field reliability of unpassivated GaN/AlGaN/GaN HEMTs显示文摘 | MENEGHESSO G RAMPAZZO F KORDOS P | 2006 | IEEE Trans Electron Devices2006，53，12： | 1 |
| 9 | Clinical profile of four families with arrhythmogenic right ventricular cardiomyopathy caused by dominant desmoplakin mutations显示文摘 | Bauce B Basso C Rampazzo A | 2005 | Eur Heart J2005，26，16： | 1 |
| 10 | Intratumoral hypoxie gradient drives stem cells distribution and MGMT expression in glioblastoma显示文摘 | Pistollato F Abbadi S Rampazzo E | 2010 | Stem cells2010，28，5： | 1 |
| 11 | Contribution of Saharan dust to the central Mediterranean basin 显示文摘 | Molinaroli E Guerzoni S Rampazzo G | 1993 | Geological Society of America (special paper )1993，284，： | 1 |
| 12 | 5'-Nucleotidases:specific assays for five different enzymes in cell extracts显示文摘 | RAMPAZZO C MAZZON C REICHARD P | 2002 | Biochem Biophys Res Commun2002，293，1： | 1 |
| 13 | Screening for ryanodine receptor type 2 mutations in families with effort-induced polymorphic ventricular arrhythmias and sudden death : early diagnosis of asymptomatic carriers显示文摘 | Bauce B Rampazzo A Basso C | 2002 | J Am Coll Cardiol2002，40，： | 1 |
| 14 | Cur- rent collapse and high-electric-field reliability of unpas- sivated GaN/A1GaN/GaN HEMTs显示文摘 | Meneghesso G Rampazzo F Kord6s P | 2006 | IEEE Electron Devices2006，53，12： | 1 |
| 15 | BMP2 sensitizes glio- blastoma stem-like cells to Temozolomide by affecting HIF-loL sta- bility and MGMT expression显示文摘 | Persano L Pistollato F Rampazzo E | 2012 | Cell Death Dis2012，3，10： | 1 |
| 16 | Compound and Digenic Heterozygosity Predicts Lifetime Arrhythmic Outcome and Sudden Cardiac Death in Desmosomal Gene–Related Arrhythmogenic Right Ventricular Cardiomyopathy显示文摘 | Ilaria Rigato Barbara Bauce Alessandra Rampazzo Alessandro Zorzi Kalliopi Pilichou Elisa Mazzotti Federico Migliore Martina Perazzolo Marra Alessandra Lorenzon Marzia De Bortoli Martina Calore Andrea Nava Luciano Daliento Dario Gregori Sabino Iliceto Gaet | 2013 | Circulation: Cardiovascular Genetics2013，，6： | 1 |
| 17 | Simultaneous restoration of voice function and digestive tract continuity in patients with synchronous primaries of hypopharynx and thoracic esophagus with pedicled ileoc,Clon flap显示文摘 | Chen HC Gharb BB Rampazzo A | 2011 | Surgery2011，149，5： | 1 |
| 18 | Hypoxia and succinate antagonize 2-deoxyglucose effects on glioblastoma显示文摘 | Pistollato F Abbadi S Rampazzo E | | 0，，10： | 1 |
| 19 | Relationship between tumor and plasma levels of hTERT mRNA in patients with colorectal cancer: implications for monitoring of neoplastic disease显示文摘 | Terrin L Rampazzo E Pucciarelli S | 2008 | Clin Cancer Res2008，14，22： | 1 |
| 20 | J Am Chem Soc显示文摘 | Zanarini S Rampazzo E Ciana L D Marcaccio M Marzocchi E Montalti M Paolucci F Prodi L | 2009 | 131:22602009，131，： | 1 |
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