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| 1 | The development of Terminalia chebula Retz.(Combretaceae) in clinical research显示文摘Medicinal plants are part and parcel of human society to combat diseases from the dawn of civilization.Terminalia chebula Retz.(Fam.Combretaceae),is called the‘King of Medicine??in Tibet and is always listed at the lop of the list of‘Ayurvedic Materia Medica??because of its extraordinary power of healing.The whole plant possesses high medicinal value and traditionally used for the treatment of various ailments for human beings.Some of the folklore people used this plant in the treatment of asthma,sore throat,vomiting,hiccough,diarrhea,dysentery,bleeding piles,ulcers,gout,heart and bladder diseases.The plant has been demonstrated to possess multiple pharmacological and medicinal activities,such as antioxidant,antimicrobial,antidiabetic,hepatoprotective,anti-inflammatory,antimutagenic,antiproliferative,radioprotective,cardioprotective,antiarthritic,anticaries,gastrointestinal motility and wound healing activity.But no systematic updated information on the therapeutic effectiveness of Terminalia chebula,a popular herbal remedy in India and South-East Asia has so far been reported.This review highlights an updated information particularly on the phytochemistry and various pharmacological and medicinal properties of Terminalia chebula Retz.and some of its isolated compounds,along with their safety evaluation.This may provide incentive for proper evaluation of the plant as medicinal agent against the human diseases and also to bridge the lacunae in the existing literature and future scope which may offer immense opportunity for researchers engaged in validation of the traditional claims and development of safe and effective botanical medicine. | Anwesa Bag Subir Kumar Bhattacharyya Rabi Ranjan Chattopadhyay | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，3： | 17 |
| 2 | All-optical active THz metasurfaces for ultrafast polarization switching and dynamic beam splitting显示文摘Miniaturized ultrafast switchable optical components with an extremely compact size and a high-speed response will be the core of next-generation all-optical devices instead of traditional integrated circuits,which are approaching the bottleneck of Moore’s Law.Metasurfaces have emerged as fascinating subwavelength flat optical components and devices for light focusing and holography applications.However,these devices exhibit a severe limitation due to their natural passive response.Here we introduce an active hybrid metasurface integrated with patterned semiconductor inclusions for all-optical active control of terahertz waves.Ultrafast modulation of polarization states and the beam splitting ratio are experimentally demonstrated on a time scale of 667 ps.This scheme of hybrid metasurfaces could also be extended to the design of various free-space all-optical active devices,such as varifocal planar lenses,switchable vector beam generators,and components for holography in ultrafast imaging,display,and high-fidelity terahertz wireless communication systems. | Longqing Cong Yogesh Kumar Srivastava Huifang Zhang Xueqian Zhang Jiaguang Han Ranjan Singh | 2018 | Light(Science & Applications)2018，7，1： | 15 |
| 3 | Determination of blast-induced ground vibration equations for rocks using mechanical and geological properties显示文摘In the recent decades,effects of blast loads on natural and man-made structures have gained considerable attention due to increase in threat from various man-made activities.Site-specific empirical relationships for calculation of blast-induced vibration parameters like peak particle velocity(PPV) and peak particle displacement(PPD) are commonly used for estimation of blast loads in design.However,these relationships are not able to consider the variation in rock parameters and uncertainty of in situ conditions.In this paper,a total of 1089 published blast data of various researchers in different rock sites have been collected and used to propose generalized empirical model for PPV by considering the effects of rock parameters like unit weight,rock quality designation(RQD),geological strength index(GSI),and uniaxial compressive strength(UCS).The proposed PPV model has a good correlation coefficient and hence it can be directly used in prediction of blast-induced vibrations in rocks.Standard errors and coefficient of correlations of the predicted blast-induced vibration parameters are obtained with respect to the observed field data.The proposed empirical model for PPV has also been compared with the empirical models available for blast vibrations predictions given by other researchers and found to be in good agreement with specific cases. | Ranjan Kumar Deepankar Choudhury Kapilesh Bhargava | 2016 | Journal of Rock Mechanics and Geotechnical Engineering2016，8，3： | 11 |
| 4 | Rock fragmentation control in opencast blasting显示文摘The blasting operation plays a pivotal role in the overall economics of opencast mines.The blasting subsystem affects all the other associated sub-systems,i.e.loading,transport,crushing and milling operations.Fragmentation control through effective blast design and its effect on productivity are the challenging tasks for practicing blasting engineer due to inadequate knowledge of actual explosive energy released in the borehole,varying initiation practice in blast design and its effect on explosive energy release characteristic.This paper describes the result of a systematic study on the impact of blast design parameters on rock fragmentation at three mines in India.The mines use draglines and shoveledumper combination for removal of overburden.Despite its pivotal role in controlling the overall economics of a mining operation,the expected blasting performance is often judged almost exclusively on the basis of poorly defined parameters such as powder factor and is often qualitative which results in very subjective assessment of blasting performance.Such an approach is very poor substitutes for accurate assessment of explosive and blasting performance.Ninety one blasts were conducted with varying blast designs and charging patterns,and their impacts on the rock fragmentation were documented.A high-speed camera was deployed to record the detonation sequences of the blasts.The efficiency of the loading machines was also correlated with the mean fragment size obtained from the fragmentation analyses. | P.K.Singh M.P.Roy R.K.Paswan Md.Sarim Suraj Kumar Rakesh Ranjan Jha | 2016 | Journal of Rock Mechanics and Geotechnical Engineering2016，8，2： | 5 |
| 5 | A review on dump slope stabilization by revegetation with reference to indigenous plant显示文摘The waste,subgrade ROM and fine dumps of iron ore mines are characterized by high rock fragment contents,low moisture retention capacity,higher bulk density,low nutrients,lower pH and elevated metal concentrations.Use of suitable revegetation programme,that require the selection of right type of plants to be used vis-à-vis the site condition and characteristics,can enhance the long-term stability,both mechanical and ecological,of dumps(waste,subgrade ROM and fines)through providing vegetative cover to control soil erosion and gully formation,consolidation of dump top and side surfaces,binding the loose particles through intricate roof system,etc.This paper overviews the roles of revegetation programme that can be used where vegetation is considered to be the long-term answer to slope protection and erosion control.Various revegetation processes like Coir matting,lemon grass,vetiver grass and indigenous plant may find a wide range of usage in iron ore mines for dump stabilization.The Miyawaki method of plantation is more effective than the conventional method of plantation.This will lead to co-existence of plants,and as a matter of fact each plant draws from the other vital nutrients and they grow to become strong and healthy.The Miyawaki plantation technique aims at“survival of the fittest”,and the area which undergone such plantation has an ecology of their own.The indigenous plant has good binding capacity and helps to control soil erosion as well as improve the dump stability.These indigenous plant species include Shorea robusta(Sal),Dalbergia sisoo(Shisham),Karanj and Azadirachta(Neem).The growth of indigenous plants is dependent upon the soil quality as well as the organic matter of the dump material.The leaf debris plays an important role for improving the organic matter of the dump material to successfully implement the revegetation programme. | Vibhash Ranjan Phalguni Sen Dheeraj Kumar Arjun Sarsawat | 2015 | Ecological Processes2015，4，1： | 5 |
| 6 | 有机微量元素对家畜免疫、健康、生产和繁殖的影响显示文摘<正>矿物质在动物一生中起着多种非常重要的作用。与其他营养素相比,其需要量很低,日粮缺乏微量元素会导致动物生产性能下降20%~30%。因此在生产实践中通常添加微量元素,以确保动物快速生长,提高繁殖性能并增强免疫应答能力。目前在动物饲料中通常添加无机盐形式的微量元素,如硫酸盐和氯化物,但无机来源的微量元素生物利用率与饲料和草料来源的矿物质并不完全等同。最新研究进展表明,如果以有机形式补充,微量元素的吸收和利用率会更高。矿物质在动物一生中起着多种非常重要的作用。与其他营养素相比,其需要量很低,日粮缺乏微量元素会导致动物生产性能下降20%~30%。因此在生产实践中通常添加微量元素,以确保动物快速生长,提高繁殖性能并增强免疫应答能力。 | 张江 Ranjan Kumar Mohanta Anil Kumar Garg | 2015 | 国外畜牧学(猪与禽)2015，0，2： | 5 |
| 7 | All ileo-cecal ulcers are not Crohn's:Changing perspectives of symptomatic ileocecal ulcers显示文摘AIM To investigated clinical,endoscopic and histopathological parameters of the patients presenting with ileocecal ulcers on colonoscopy.METHODS Consecutive symptomatic patients undergoing colonoscopy,and diagnosed to have ulcerations in the ileocecal(I/C) region,were enrolled.Biopsy was obtained and theirclinical presentation and outcome were recorded.RESULTS Out of 1632 colonoscopies,104 patients had ulcerations in the I/C region and were included in the study.Their median age was 44.5 years and 59% were males.The predominant presentation was lower GI bleed(55,53%),pain abdomen ± diarrhea(36,35%),fever(32,31%),and diarrhea alone(9,9%).On colonoscopy,terminal ileum was entered in 96(92%) cases.The distribution of ulcers was as follows:Ileum alone 40%(38/96),cecum alone 33%(32/96),and both ileum plus cecum 27%(26/96).The ulcers were multiple in 98% and in 34% there were additional ulcers elsewhere in colon.Based on clinical presentation and investigations,the etiology of ulcers was classified into infective causes(43%) and noninfective causes(57%).Fourteen patients(13%) were diagnosed to have Crohn's disease(CD).CONCLUSION Non-specific ileocecal ulcers are most common ulcers seen in ileo-cecal region.And if all infections are clubbed together then infection is the most common(> 40%) cause of ulcerations of the I/C region.Cecal involvement and fever are important clues to infective cause.On the contrary CD account for only 13% cases as a cause of ileo-cecalulcers.So all symptomatic patients with I/C ulcers on colonoscopy are not Crohn's. | Jay Toshniwal Romesh Chawlani Amit Thawrani Rajesh Sharma Anil Arora Hardik L Kotecha Mohan Goyal Vijendra Kirnake Pankaj Jain Pankaj Tyagi Naresh Bansal Munish Sachdeva Piyush Ranjan Mandhir Kumar Praveen Sharma Vikas Singla Rinkesh Bansal Vineet Shah Sunita Bhalla Ashish Kumar | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，7： | 5 |
| 8 | Geochemical characteristics and mode of occurrence of trace elements in coal at West Bokaro coalfield显示文摘 | Sk. Md. Equeenuddin Subhasish Tripathy Prafuila Kumar Sahoo Amit Ranjan | 2016 | International Journal of Coal Science & Technology2016，3，4： | 4 |
| 9 | Graphene-induced Pd nanodendrites: A high performance hybrid nanoelectrocatalyst显示文摘一条灵巧、绿的途径被开发了为在里面基于塑造树突的 Pd, nanostructures 在 graphene (RG ) 上支持了的混合 nanomaterials 的 situ 合成。同样综合的混合 nanomaterials (RG-PdnDs ) 被高分辨率传播电子显微镜学, X 光检查光电子光谱学,原子力量显微镜学,拉曼光谱学和电气化学的技术彻底地描绘了。graphene 支持上的如此的塑造树突的 Pd nanostructures 的形成的机制用 TEM 大小被阐明了。RG 导致形成,并且在塑造起一个明确的作用,它的表面上的 Pd nanostructures 的树突形态学。周期的 voltammetry 和 chronoamperometry 技术被采用了向甲醇的氧化评估 RG-PdnDs 的电气化学的表演。电气化学(EC ) RG-PdnDs 的活动与支持 graphene 的球形形状的 Pd nanostructures,独自一个的 Pd nanodendrites 和商业可得到的 Pd/C 相比对应物。graphene 支持的联合效果和 RG-PdnDs 的树突形态学触发高 electrocatalytic 活动并且导致柔韧的忍耐到毒害的公司。 | Subash Chandra Sahu Aneeya K. Samantarat Ajit Dash R. R. Juluri Ranjan K. Sahu B. K. Mishra Bikash Kumar Jena (1~3) | 2013 | Nano Research2013，6，9： | 4 |
| 10 | Genetic Relationship and Structure Analysis of Root Growth Angle for Improvement of Drought Avoidance in Early and Mid-Early Maturing Rice Genotypes显示文摘Deeper rooting 1(Dro1)and Deeper rooting 2(Dro2)are the QTLs that contribute considerably to root growth angle assisting in deeper rooting of rice plant.In the present study,a set of 348 genotypes were shortlisted from rice germplasm based on root angle study.Screening results of the germplasm lines under drought stress identified 25 drought tolerant donor lines based on leaf rolling,leaf drying,spikelet fertility and single plant yield.A panel containing 101 genotypes was constituted based on screening results and genotyped using Dro1 and Dro2 markers.Structure software categorized the genotypes into four sub-populations with different fixation index values for root growth angle.The clustering analysis and principal coordinate analysis could differentiate the genotypes with or without deeper rooting trait.The dendrogram constructed based on the molecular screening for deep rooting QTLs showed clear distinction between the rainfed upland cultivars and irrigated genotypes.Eleven genotypes,namely Dular,Tepiboro,Surjamukhi,Bamawpyan,N22,Dinorado,Karni,Kusuma,Bowdel,Lalsankari and Laxmikajal,possessed both the QTLs,whereas 67 genotypes possessed only Dro1.The average angle of Dro positive genotypes ranged from 82.7°to 89.7°.These genotypes possessing the deeper rooting QTLs can be taken as donor lines to be used in marker-assisted breeding programs. | Elssa PANDIT Rajendra Kumar PANDA Auromeera SAHOO Dipti Ranjan PANI Sharat Kumar PRADHAN | 2020 | Rice science2020，27，2： | 4 |
| 11 | Leukemic stromal hematopoietic microenvironment negatively regulates the normal hematopoiesis in mouse model of leukemia显示文摘Background and Objective: Leukemic microenvironment has a major role in the progression of leukemia. Leukemic cells can induce reversible changes in microenvironmental components, especially the stromal function which results in improved growth conditions for maintaining the malignant leukemic cells. This study aimed to investigate the survival advantage of leukemic cells over normal hematopoietic cells in stromal microenvironment in long term. Methods: The mice were injected intraperitoneally with N-N’ ethylnitrosourea (ENU) to induce leukemia; the mice received injection of normal saline were used as control. At 180 days after ENU induction, the mice were killed and the bone marrows were cultured for 19 days. Colony-forming assays were used to analyze the formation of various cell colonies. The expression of Sca-1, CD146, VEGFR2, CD95, pStat3, pStat5, and Bcl-xL in marrow cells were detected by flow cytometry. Results: Long-term leukemic bone marrow culture showed abnormal elongated stromal fibroblasts with almost absence of normal hematopoietic cells. Adherent cell colonies were increased, but CFU-F and other hematopoietic cell colonies were significantly decreased in leukemia group (P< 0.001). Primitive progenitor-specific Sca-1 receptor expression was decreased with subsequent increased expression of CD146 and VEGFR-2 in leukemic bone marrow cells. Decreased Fas antigen expression with increased intracellular pStat3, pStat5 and Bcl-xL proteins were observed in leukemic bone marrow cells. Conclusions: Stromal microenvironment shows altered morphology and decreased maturation in leukemia. Effective progenitor cells are decreased in leukemia with increased leukemia-specific cell population. Leukemic microenvironment plays a role in promoting and maintaining the leukemic cell proliferation and survivability in long term. | Pratima Basak Sumanta Chatterjee Prosun Das Madhurima Das Jacintha Archana Pereira Ranjan Kumar Dutta Malay Chaklader Samaresh Chaudhuri Sujata Law | 2010 | Chinese Journal of Cancer2010，29，12： | 3 |
| 12 | Translational products of adipose tissue-derived mesenchymal stem cells:Bench to bedside applications显示文摘With developments in the field of tissue engineering and regenerative medicine,the use of biological products for the treatment of various disorders has come into the limelight among researchers and clinicians.Among all the available biological tissues,research and exploration of adipose tissue have become more robust.Adipose tissue engineering aims to develop by-products and their substitutes for their regenerative and immunomodulatory potential.The use of biodegradable scaffolds along with adipose tissue products has a major role in cellular growth,proliferation,and differentiation.Adipose tissue,apart from being the powerhouse of energy storage,also functions as the largest endocrine organ,with the release of various adipokines.The progenitor cells among the heterogeneous population in the adipose tissue are of paramount importance as they determine the capacity of regeneration of these tissues.The results of adipose-derived stemcell assisted fat grafting to provide numerous growth factors and adipokines that improve vasculogenesis,fat graft integration,and survival within the recipient tissue and promote the regeneration of tissue are promising.Adipose tissue gives rise to various by-products upon processing.This article highlights the significance and the usage of various adipose tissue by-products,their individual characteristics,and their clinical applications. | Shilpa Sharma Sathish Muthu Madhan Jeyaraman Rajni Ranjan Saurabh Kumar Jha | 2021 | World Journal of Stem Cells2021，13，10： | 3 |
| 13 | Magnetic separation studies for a low grade siliceous iron ore sample显示文摘Investigations were carried out, on a low grade siliceous iron ore sample by magnetic separation, to establish its amenability for physical beneficiation. Mineralogical studies revealed that the sample consists of magnetite, hematite and goethite as major opaque oxide minerals where as silicates as well as carbonates form the gangue minerals in the sample. Processes involving combination of classification, dry magnetic separation and wet magnetic separation were carried out to upgrade the low grade siliceous iron ore sample to make it suitable as a marketable product. The sample was first ground and each closed size sieve fractions were subjected to dry magnetic separation and it was observed that limited upgradation is possible. The ground sample was subjected to different finer sizes and separated by wet low intensity magnetic separator. It was possible to obtain a magnetic concentrate of 67% Fe by recovering 90% of iron values at below 200 lm size. | Dwari Ranjan Kumar Rao Danda Srinivas Reddy Palli Sita Ram | 2013 | International Journal of Mining Science and Technology2013，23，1： | 3 |
| 14 | Characterization of dolochar wastes generated by the sponge iron industry显示文摘Solid wastes generated by the metallurgical industry contribute significantly towards the enhancement of environmental pollution. The handling, utilization, and safe disposal of these solid wastes are major concerns for the world. Dolochar is such a solid waste generated by the sponge iron industry. Investigations were carried out on the physical, mineralogical, and chemical characteristics for the efficient utilization of dolochar. The detailed studies on physico-chemical properties and petrography were carried out by optical microscopy, X-ray diffraction (XRD), and scanning electron microscopy (SEM). Characterization studies revealed that the dolochar consists of quartz (free as well as locked), free lime, Fe particles, and Ca or Mg and/or Ca+Mg+Fe oxide phases. The washability data of-300 μm dolochar samples indicated that clean coal with 41wt% ash at 18% yield can be produced from dolochar with 78wt% ash. The studies further suggested that the liberation of the dolochar is hard to achieve for clear separation. The dolochar is observed to have high ash fusion temperature and the unburned carbon can be best utilized for power generation. | Ranjan Kumar Dwari Danda Srinivas Rao Akhila Kumar Swar Palli Sita Ram Reddy Barada Kanta Mishra | 2012 | International Journal of Minerals,Metallurgy and Materials2012，19，11： | 2 |
| 15 | EMD-Att-LSTM: A Data-driven Strategy Combined with Deep Learning for Short-term Load Forecasting显示文摘Electric load forecasting is an efficient tool for system planning, and consequently, building sustainable power systems. However, achieving desirable performance is difficult owing to the irregular, nonstationary, nonlinear, and noisy nature of the observed data. Therefore, a new attention-based encoderdecoder model is proposed, called empirical mode decomposition-attention-long short-term memory(EMD-Att-LSTM).EMD is a data-driven technique used for the decomposition of complex series into subsequent simpler series. It explores the inherent properties of data to obtain the components such as trend and seasonality. Neural network architecture driven by deep learning uses the idea of a fine-grained attention mechanism, that is, considering the hidden state instead of the hidden state vectors, which can help reflect the significance and contributions of each hidden state dimension. In addition, it is useful for locating and concentrating the relevant temporary data,leading to a distinctly interpretable network. To evaluate the proposed model, we use the repository dataset of Australian energy market operator(AEMO). The proposed architecture provides superior empirical results compared with other advanced models. It is explored using the indices of root mean square error(RMSE) and mean absolute percentage error(MAPE). | Neeraj Jimson Mathew Ranjan Kumar Behera | 2022 | Journal of Modern Power Systems and Clean Energy2022，10，5： | 2 |
| 16 | The Development of Efficient Plant Promoters for Transgene Expression Employing Plant Virus Promoters显示文摘Dear Editor, The structure of eukaryotic promoter is modular,consisting of different sub-domains(Benfey et al.,1990).Cross-talk among these sub-domains and effective combinatorial interactions between the specific cis-elementJs with respective transfactor/s usually control the strength and tissue specificity of the promoter.Further,specificity/inducibility of promoter can be modified by altering its genetic architecture through ‘cis-rearrangement'(Rushton et al.,2002)and ‘swapping of sub-domains'(Bhullar et al.,2003). | Sunita Patro Deepak Kumar Rajiv Ranjan Indu B.Maiti Nrisingha Dey | 2012 | Molecular Plant2012，5，4： | 2 |
| 17 | Effect of potassium on soil conservation and productivity of maize/cowpea based crop rotations in the north-west Indian Himalayas显示文摘Plots under conservation tillage may require higher amount of potassium(K) application for augmenting productivity due to its stratification in upper soil layers, thereby reducing K supplying capacity in a medium or long-term period. To test this hypothesis, a field experiment was performed in 2002-2003 and 2006-2007 to study the effect of K and several crop rotations on yield, water productivity, carbon sequestration, grain quality, soil K status and economic benefits derived in maize(Zea mays L)/cowpea(Vigna sinensis L.) based cropping system under minimum tillage(MT). All crops recorded higher grain yield with a higher dose of K(120 kg K2 O ha-1) than recommended K(40 kg K2 O ha-1). The five years' average yield data showed that higher K application(120 kg K2 O ha-1) produced 16.4%(P<0.05)more maize equivalent yield. Cowpea based rotation yielded 14.2%(P<0.05) higher production than maize based rotation. The maximum enhancement was found in cowpea-mustard rotation. Relationship between yield and sustainable indices revealed that only agronomic efficiency of fertilizer input was significantly correlated with yield. Similarly, higherdoses of K application not only increased the water use efficiency(WUE) of all crops, but also reduced runoff and soil loss by 16.5% and 15.8% under maize and 23.3% and 19.7% under cowpea cover, respectively. This study also revealed that on an average 16.5% of left over carbon input contributed to soil organic carbon(SOC). Here, cowpea based rotation with the higher K application increased carbon sequestration in soil. Potassium fertilization also significantly improved the nutritional value of harvested grain by increasing the protein content for maize(by 9.5%) and cowpea(by 10.6%). The oil content in mustard increased by 5.0% and 6.0% after maize and cowpea, respectively. Net return also increased with the application of the higher K than recommended K and the trend was similar to yield. Hence, the present study demonstrated the potential yield and profit gains along with resource conservation in the Indian Himalayas due to annual additions of higher amount of K than the recommended dose. The impact of high K application was maximum in the cowpea-mustard rotation. | Birendra Nath GHOSH Om Pal Singh KHOLA Ranjan BHATTACHARYYA Kuldeep Singh DADHWAL Prasant Kumar MISHRA | 2016 | Journal of Mountain Science2016，13，4： | 2 |
| 18 | Diagnostic assays developed for the control of foot-andmouth disease in India显示文摘Foot-and-mouth disease(FMD) is a highly contagious and economically devastating disease of livestock, primarily affecting cattle, buffalo and pigs. FMD virus serotypes O, A and Asia1 are prevalent in India and systematic efforts are on to control and eventually eradicate the disease from the country. FMD epidemiology is complex due to factors like co-circulation, extinction, emergence and re-emergence of genotypes/lineages within the three serotypes, animal movement, diverse farm practices and large number of susceptible livestock in the country. Systematic vaccination, prompt diagnosis, strict biosecurity measures, and regular monitoring of vaccinal immunity and surveillance of virus circulation are indispensible features for the effective implementation of the control measures. Availability of suitable companion diagnostic tests is very important in this endeavour. In this review, the diagnostic assays developed and validated in India and their contribution in FMD control programme is presented. | Gaurav Kumar Sharma Sonalika Mahajan Rakesh Matura Saravanan Subramaniam Rajeev Ranjan Jitendra Biswal Manoranjan Rout Jajati Keshari Mohapatra Bana Bihari Dash Aniket Sanyal Bramhadev Pattnaik | 2015 | World Journal of Virology2015，4，3： | 2 |
| 19 | Assessment of plant nitrogen stress in wheat (Triticum aestivum L.) through hyperspectral indices显示文摘 | Rajeev Ranjan Usha Kiran Chopra RabiN. Sahoo Anil Kumar Singh Sanatan Pradhan | 2012 | International Journal of Remote Sensing2012，，20： | 2 |
| 20 | Nanofat: A therapeutic paradigm in regenerative medicine显示文摘Adipose tissue is a compact and well-organized tissue containing a heterogeneous cellular population of progenitor cells,including mesenchymal stromal cells.Due to its availability and accessibility,adipose tissue is considered a“stem cell depot.”Adipose tissue products possess anti-inflammatory,anti-fibrotic,antiapoptotic,and immunomodulatory effects.Nanofat,being a compact bundle of stem cells with regenerative and tissue remodeling potential,has potential in translational and regenerative medicine.Considering the wide range of applicability of its reconstructive and regenerative potential,the applications of nanofat can be used in various disciplines.Nanofat behaves on the line of adipose tissuederived mesenchymal stromal cells.At the site of injury,these stromal cells initiate a site-specific reparative response comprised of remodeling of the extracellular matrix,enhanced and sustained angiogenesis,and immune system modulation.These properties of stromal cells provide a platform for the usage of regenerative medicine principles in curbing various diseases.Details about nanofat,including various preparation methods,characterization,delivery methods,evidence on practical applications,and ethical concerns are included in this review.However,appropriate guidelines and preparation protocols for its optimal use in a wide range of clinical applications have yet to be standardized. | Madhan Jeyaraman Sathish Muthu Shilpa Sharma Charan Ganta Rajni Ranjan Saurabh Kumar Jha | 2021 | World Journal of Stem Cells2021，13，11： | 2 |
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