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| 1 | Unusual disposition of lateral circumflex femoral artery: Anatomical description and clinical implications显示文摘The anatomical knowledge of arterial variations of lower limb is of utmost significance for the present day surgeons and interventional radiologists for minimizing complications during vascular reconstructive procedures, catheterization procedures and surgical intervention for embolism. Lateral Circumflex Femoral Artery(LCFA) isan important branch of Profunda Femoris artery and precise knowledge of its variations can be of great relevance during surgical and radiological procedures in femoral region. The present study reports a unique case of anomalous route taken by LCFA posterior to femoral nerve associated with a prominent muscular branch from Femoral artery mimicking the course of LCFA. Documentation of such variations is highly significant. It may serve as guideline for surgeons in reducing the incidence of postoperative complications where LCFA is used as a long vascular pedicle in anterolateral perforator thigh flap and in breast reconstruction after mastectomy. Ignorance of such variations can lead to fatal intraoperative haemorrhage and incapacitating sensory and motor deficit due to injury to femoral nerve branches which are closely related to these vessels. | Shivi Goel Jyoti Arora Vandana Mehta Mona Sharma Rajesh Kumar Suri Gayatri Rath | 2015 | World Journal of Clinical Cases2015，3，1： | 11 |
| 2 | Oxidative Stressand Antioxidant Responses in Young Leaves of Mulberry Plants Grown Under Nitrogen, Phosphorus or Potassium Deficiency显示文摘 | Rajesh Kumar Tewari Praveen Kumar Parma Nand Sharma | 2007 | Journal of Integrative Plant Biology2007，49，3： | 10 |
| 3 | Management of hypersplenism in non-cirrhotic portal hypertension:a surgical series显示文摘BACKGROUND:Hypersplenism is commonly seen in patients with non-cirrhotic portal hypertension(NCPH).While a splenectomy alone can effectively relieve the hypersplenism,it does not address the underlying portal hypertension.The present study was undertaken to analyze the impact of shunt and non-shunt operations on the resolution of hypersplenism in patients with NCPH.The relationship of symptomatic hypersplenism,severe hypersplenism and number of peripheral cell line defects to the severity of portal hypertension and outcome was also assessed.METHODS:A retrospective analysis of NCPH patients with hypersplenism managed surgically between 1999 and 2009 at our center was done.Of 252 patients with NCPH,64(45 with extrahepatic portal vein obstruction and 19 with non-cirrhotic portal fibrosis) had hypersplenism and constituted the study group.Statistical analysis was done using GraphPad InStat.Categorical and continuous variables were compared using the chi-square test,ANOVA,and Student's t test.The MannWhitney U test and Kruskal-Wallis test were used to compare non-parametric variables.RESULTS:The mean age of patients in the study group was 21.81±6.1 years.Hypersplenism was symptomatic in 70.3% with an incidence of spontaneous bleeding at 26.5%,recurrent anemia at 34.4%,and recurrent infection at 29.7%.The mean duration of surgery was 4.16±1.9 hours,intraoperative blood loss was 457±126(50-2000) mL,and postoperative hospital stay 5.5±1.9 days.Following surgery,normalization of hypersplenism occurred in all patients.On long-term followup,none of the patients developed hepatic encephalopathy and 4 had a variceal re-bleeding(2 after a splenectomy alone,1 each after an esophago-gastric devascularization and proximal splenorenal shunt).Patients with severe hypersplenism and those with defects in all three peripheral blood cell lineages were older,had a longer duration of symptoms,and a higher incidence of variceal bleeding and postoperative morbidity.In addition,patients with triple cell line defects had elevated portal pressure(P=0.001),portal biliopathy(P=0.02),portal gastropathy(P=0.005) and intraoperative blood loss(P=0.001).CONCLUSIONS:Hypersplenism is effectively relieved by both shunt and non-shunt operations.A proximal splenorenal shunt not only relieves hypersplenism but also effectively addresses the potential complications of underlying portal hypertension and can be safely performed with good long-term outcome.Patients with hypersplenism who have defects in all three blood cell lineages have significantly elevated portal pressures and are at increased risk of complications of variceal bleeding,portal biliopathy and gastropathy. | Rajesh Rajalingam Amit Javed Dharmanjay Sharma Puja Sakhuja Shivendra Singh Hirdaya H Nag Anil K Agarwal | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，2： | 7 |
| 4 | All ileo-cecal ulcers are not Crohn's:Changing perspectives of symptomatic ileocecal ulcers显示文摘AIM To investigated clinical,endoscopic and histopathological parameters of the patients presenting with ileocecal ulcers on colonoscopy.METHODS Consecutive symptomatic patients undergoing colonoscopy,and diagnosed to have ulcerations in the ileocecal(I/C) region,were enrolled.Biopsy was obtained and theirclinical presentation and outcome were recorded.RESULTS Out of 1632 colonoscopies,104 patients had ulcerations in the I/C region and were included in the study.Their median age was 44.5 years and 59% were males.The predominant presentation was lower GI bleed(55,53%),pain abdomen ± diarrhea(36,35%),fever(32,31%),and diarrhea alone(9,9%).On colonoscopy,terminal ileum was entered in 96(92%) cases.The distribution of ulcers was as follows:Ileum alone 40%(38/96),cecum alone 33%(32/96),and both ileum plus cecum 27%(26/96).The ulcers were multiple in 98% and in 34% there were additional ulcers elsewhere in colon.Based on clinical presentation and investigations,the etiology of ulcers was classified into infective causes(43%) and noninfective causes(57%).Fourteen patients(13%) were diagnosed to have Crohn's disease(CD).CONCLUSION Non-specific ileocecal ulcers are most common ulcers seen in ileo-cecal region.And if all infections are clubbed together then infection is the most common(> 40%) cause of ulcerations of the I/C region.Cecal involvement and fever are important clues to infective cause.On the contrary CD account for only 13% cases as a cause of ileo-cecalulcers.So all symptomatic patients with I/C ulcers on colonoscopy are not Crohn's. | Jay Toshniwal Romesh Chawlani Amit Thawrani Rajesh Sharma Anil Arora Hardik L Kotecha Mohan Goyal Vijendra Kirnake Pankaj Jain Pankaj Tyagi Naresh Bansal Munish Sachdeva Piyush Ranjan Mandhir Kumar Praveen Sharma Vikas Singla Rinkesh Bansal Vineet Shah Sunita Bhalla Ashish Kumar | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，7： | 5 |
| 5 | Effect of stacking sequence on physical, mechanical and tribological properties of glass-carbon hybrid composites显示文摘A study was done to determine the effect of best stacking sequence(position and orientation)on the mechanical properties,friction and wear response of hybrid composites.The main purpose of the study was to determine the best available stacking sequence for which the physical,mechanical and three body abrasive wear rate is optimum.Test for mechanical properties(tensile strength,flexural strength,inter laminar shear strength,impact strength and hardness)was done on glass-carbon hybrid composites.The composites were then subjected to test for three body abrasive wear on a designed experimental setup.Five different factors(sliding velocity,fabric weight percentage,normal load,sliding distance and abrasive particle size)varied in steps to evaluate the friction and three body abrasive wear response of the composites.The design of experiment using Taguchi’s orthogonal array and analysis of variance(ANOVA)was applied to find out minimum specific wear rate.The results revealed the significance in arrangement of two different layers of fabric(glass and carbon)and the difference in properties obtained by them.Using Taguchi experimental analysis it has been observed that three body abrasive wear rate is minimum at 72 cm/s sliding velocity,30 wt.%fabric content,80 N normal load,90 m sliding distance and 125μm abrasive particle size.The scanning electron microscope(SEM)studies revealed the dynamics of three‐body abrasive wear and underlying micro‐mechanisms that result in the analysis of three body abrasive wear. | Gaurav AGARWAL Amar PATNAIK Rajesh kumar SHARMA Jyoti AGARWAL | 2014 | Friction2014，2，4： | 4 |
| 6 | Anti-mycobacterial screening of five Indian medicinal plants and partial purification of active extracts of Cassia sophera and Urtica dioica显示文摘Objective:To find out the anti-mycobacterial potential of Cassia sophera(C.sophera),Urtica dioica(U.dioica),Momordica dioica,Tribulus terrains and Coccinia indica plants against multidrug resistant(MDR) strain of Mycobacterium tuberculosis(M.tuberculosis).Methods:Plant materials were extracted successively with solvents of increasing polarity.Solvent extracts were screened for anti-mycobacterial activity against fast growing,non-pathogenic mycobacterium strain,Mycobacterium semegmatis,by disk diffusion method.The active extracts were tested against MDR and clinical isolates of M.tuberculosis by absolute concentration and proportion methods.The active extracts were subjected to bio-autoassay on TLC followed by silica column chromatography for isolation of potential drug leads.Results:Hexane extract of U.dioica(HEUD) and methanol extract of C.sophera(MECS) produced inhibition zone of 20 mm in disc diffusion assay and MIC of 250 and 125μg/mL respectively in broth dilution assay against Mycobacterium semegmatis.Semipurified traction F2 from MECS produced 86%inhibition against clinical isolate and 60%inhibition against MDR strain of ilf.tuberculosis.F18 from HEUD produced 81%inhibition against clinical isolate and 60%inhibition against MDR strain of M.tuberculosis.Phytochemical analysis indicated that anti-mycobacterial activity of MECS may be due to presence of alkaloids or flavonoids and that of HEUD due to terpenoids.Condosions:C.sophera and U.dioica plant extracts exhibited promising anti-mycobacterial activity against MDR strain of M.tuberculosis. This is the first report of anti-mycobacterial activity form C.sophera.This study showed possibility of purifying novel anti-mycobacterial compound(s) from C.sophera and U.dioica. | Rambir Singh Shariq Hussain Rajesh Verma Poonam Sharma | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，5： | 4 |
| 7 | Association of periodontal disease with glycemic control in patients with type 2 diabetes in Indian population显示文摘这研究试图与长期的 periodontitis 调查在 glycated 血红素和糖尿病的复杂并发症之间的连接。有类型 2 糖尿病和长期的 periodontitis (CP ) 的 207 个病人的一个总数根据吝啬的比萨(牙齿周围的煽动的表面区域) 的 tertiles 被划分作为低、中间、高的比萨组得分。同时,一组 67 个牙齿周围地健康的个人(PH ) 被招募。包括对探查深度(PPD ) 的完整嘴的评价,在探查,临床的附件水平和匾上流血获得的牙齿周围的考试是坚定的。血分析为 glycated 血红素(HbA1c ) 被执行, fasting 血浆葡萄糖(FPG ) , 2 h 驿站 parandial 葡萄糖(PPG ) 。在 PH 的个人比 CP 组组织有的显著地更好的 glycemic 控制。在变化的单程的分析之上,有增加的比萨的题目有显著地更高的 HbA1c 层次, retinopathy 和 nephropathy (P < 0.05 ) 。在好久控制以后,性,身体团索引( BMI ),社会经济的地位( SES ),糖尿病和 periodontitis 的家庭历史,糖尿病的持续时间,在 mm2 的吝啬的比萨, PPD 4-6 公里(%)和 PPD 7 公里(%)在回归模型为提高的 HbA1c 作为重要预言者出现了( P < 0.05 )。逻辑回归分析表明那比萨与有 retinopathy 和神经病(机会比率) 的更高的风险被联系。在我们的学习,在有 periodontitis 的 glycemic 控制和糖尿病的复杂并发症之间的协会被观察。 | Palka Kaur Khanuja Satish Chander Narula Rajesh Rajputt Rajinder Kumar Sharma Shikha Tewari | 2017 | Frontiers of Medicine2017，11，1： | 4 |
| 8 | Heavy metal contamination of soil and vegetables in suburban areas of Varanasi, India显示文摘 | Rajesh Kumar Sharma Madhoolika Agrawal Fiona Marshall | 2006 | Ecotoxicology and Environmental Safety2006，，2： | 3 |
| 9 | Magnesium deficiency induced oxidative stress and antioxidant responses in mulberry plants显示文摘 | Rajesh Kumar Tewari Praveen Kumar Parma Nand Sharma | 2005 | Scientia Horticulturae2005，，1： | 2 |
| 10 | Closed reduction and percutaneous pinning of displaced supracondylar fractures of humerus in children with delayed presentation显示文摘肱骨的客观 Supracondylar 破裂在小儿科的肘附近说明 60% 所有破裂,甚至在发达国家, 18% 病人在医院里经历外科 48 小时或更长的列在后面表示。管理指南还不为谁的这些病人是清楚的在场迟了。这未来的研究的目的是评估跟随关上的减小并且在损害以后介绍 12 个小时或更多的肱骨的广泛地代替的 supracondylar 破裂的经皮的卡住的临床、放射学、功能的结果。我们考察了关上的减小并且与代替的扩展的在 40 个病人的用穿过的 K 电线的经皮的卡住的功能、放射学的结果的方法在表示与超过 12 个小时的延期打肱骨(Gartland 类型 III ) 的 supracondylar 骨折。病人的平均年龄是 4.5 年,在表示的吝啬的延期是 17.55 个小时。结果关上了减小,经皮的卡住在 90% 病人是成功的。平均数在时期上面列在后面是 15 个月。Baumann 的角度在所有病人在未受影响的方面的 4 度以内被恢复。在有严重胀大的病人的一个小中间的切口的使用帮助了我们避免尺骨的神经损害。用弗林的标准, 38 个病人(95%) 有优秀结果。二个病人有温和肌炎,两个有差的结果。任何一个都没病人开发肘脉内翻足。结论关上了减小并且交叉在孩子肱骨的代替的 supracondylar 破裂卡住甚至与推迟的表示是一个安全、有效的方法。 | Aman Dua Krishna Kiran Eachempati Rajesh Malhotra Lalit Sharma Mallinath Gidaganti | 2011 | Chinese Journal of Traumatology2011，14，1： | 2 |
| 11 | Single Pediatric Kidney Transplantation in Adult Recipients: Comparable Outcomes With Standard-Criteria Deceased-Donor Kidney Transplantation显示文摘 | Amit Sharma Rajesh Ramanathan Martha Behnke Robert Fisher Marc Posner | 2013 | Transplantation Journal2013，，11： | 2 |
| 12 | Arterial pH,bicarbonate levels and base deficit at presentation as markers of predicting mortality in acute pancreatitis:a single-centre prospective study显示文摘Background.Arterial blood gas(ABG)parameters such as pH form part of multi-parameter scoring systems for predicting severe acute pancreatitis;however,literature on detailed evaluation of ABG alone in this context is scarce.Methods.Patients with acute pancreatitis presenting to our unit between January 2012 and November 2013 were prospectively studied.ABG analysis was done at admission and development of organ failure,any need for intervention,and mortality were noted.The association between various parameters of ABG analysis and the development of organ failure or local complications,need for interventions(endoscopic/radiological/surgical)and mortality were analysed.Results.Two hundred and five patients(mean age:39.33-13.85 years;61.0%males)were prospectively studied.The aetiology of acute pancreatitis was alcohol in 93 patients(45.4%)and gall stone disease in 73(35.6%).Organ failure developed in 71.2%patients and 83.9%had local complications.In 18%of patients,endoscopic/radiological/surgical interventions were needed and 14.6%died.The patients(n=35)with metabolic acidosis(pH<7.35)suffered higher frequency of organ failure,need for interventions and mortality.Patients with low arterial bicarbonate levels,as well as higher base deficit,also displayed higher frequency of organ failure,need for interventions and mortality.The receiver operating characteristic(ROC)curves for pH<7.35,bicarbonate<22 meq/L and base deficit of>4 meq/L for prediction of mortality were 0.771(95%CI:0.664–0.878),0.707(95%CI:0.622–0.791)and 0.780(95%CI:0.693–0.867),respectively.Conclusion.Arterial pH,bicarbonate levels,and base deficit at presentation are useful early markers for predicting adverse outcome in acute pancreatitis. | Vishal Sharma Thingbaijam Shanti Devi Ravi Sharma Puneet Chhabra Rajesh Gupta Surinder S.Rana Deepak K.Bhasin | 2014 | Gastroenterology Report2014，2，3： | 1 |
| 13 | Heavy metal contamination of soil and vegetables in suburban areas of Varanasi,India 显示文摘 | Rajesh Kumar Sharma Madhoolika Agrawal Fiona Marshall | 2007 | Ecotoxicology and Environmental Safety2007，66，： | 1 |
| 14 | Adenylate cyclase activator forskolin alleviates intracerebroventricular propionic acid-induced mitochondrial dysfunction of autistic rats显示文摘Neuronal mitochondrial dysfunction increases inflammatory mediators and leads to free radical generation and anti-oxidant enzymatic alterations,which are major neuropathological hallmarks responsible for autism.Mitochondrial dysfunction in autism is associated with decreased ATP levels due to reduced levels of cyclic adenosine monophosphate.Rat models of autism were established by intracerebroventricular injection of propionic acid.These rat models had memory dysfunction,decreased muscle coordination and gait imbalance.Biochemical estimation of propionic acid-treated rats showed changes in enzyme activity in neuronal mitochondrial electron transport chain complexes and increases in pro-inflammatory cytokines,oxidative stress and lipid biomarkers.Oral administration of 10,20 and 30 mg/kg adenylate cyclase activator forskolin for 15 days reversed these changes in a dose-dependent manner.These findings suggest that forskolin can alleviate neuronal mitochondrial dysfunction and improve neurological symptoms of rats with autism.This study was approved by the RITS/IAEC,SIRSA,HARYANA on March 3,2014(approval No.RITS/IAEC/2014/03/03). | Sidharth Mehan Saloni Rahi Aarti Tiwari Tarun Kapoor Kajal Rajdev Ramit Sharma Himanshi Khera Sourabh Kosey Umesh Kukkar Rajesh Dudi | 2020 | Neural Regeneration Research2020，15，6： | 1 |
| 15 | A Hybrid Multi-Agent Based Particle Swarm Optimizstion Algorithm for Economic Power Dispatch 显示文摘 | Rajesh Kumar Debendra Sharma Abhinav Sadu | 2011 | Electrical Power and Energy Systems2011，33，1： | 1 |
| 16 | Multiple molecular targets in cancer chemoprevention by curcumin显示文摘 | Rajesh L. Thangapazham Anuj Sharma Radha K. Maheshwari | 2006 | The AAPS Journal2006，，3： | 1 |
| 17 | Magnesium deficiency induced oxidative stress and antioxidant responses in mulberry plants显示文摘 | Rajesh Kumar Tewari Praveen Kumar Parma Nand Sharma | 2005 | Scientia Horticulturae2005，，1： | 1 |
| 18 | Heavy metal contamination of soil and vegetables in suburban areas of Varanasi, India显示文摘 | Sharma Rajesh Kumar Agrawal Madhoolika Marshall Fiona | 2007 | Ecotoxicology and Environmental Safety2007，66，： | 1 |
| 19 | Solutionizing temperature and abrasive wear behaviour of cast A1-Si-Mg alloys显示文摘 | Rajesh Sharma Anesh | 2006 | Materials and Design2006，26，11： | 1 |
| 20 | Midodrine in patients with cirrhosis and refractory or recurrent ascites: A randomized pilot study显示文摘 | Virendra Singh Sahdeb P. Dhungana Baljinder Singh Rajesh Vijayverghia Chander K. Nain Navneet Sharma Ashish Bhalla Pramod K. Gupta | 2011 | Journal of Hepatology2011，，2： | 1 |
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