|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 肛裂临床诊治指南(第三次修订)显示文摘“美国结直肠外科医师协会(American Societyof ColonandRectal Surgeons.ASCRS)”(协会)致力于推进结直肠和肛门疾病的相关理论以及预防和诊疗水平的提高,给患者提供优质的医疗服务。“标准委员会”由协会中在结直肠外科方面有显著专长的成员组成。该委员会的建立是为了引领国际结直肠和肛门疾病诊治的发展,以建立具有循证医学证据的临床诊疗指南。指南是涵盖性的,非指令性的,目的是为临床决策提供信息,而非具体的治疗方法。指南适用于所有相关的医护人员以及希望得到相应指南中疾病的相关诊治信息的患者。 | Farshid Araghizadeh ~ Robin Boushey Sridhar Chalasani George Chang Robert Cima Gary Dunn Daniel Feingold Philip Fleshner Daniel Geisler Jill Genua Sharon Gregorcyk Daniel Herzig Andreas Kaiser Ravin Kumar David Larson Steven Mills John Monson P. Terry Phang Feza Remzi David Rivadeneira Howard Ross Peter Senatore Elin Sigurdson Thomas Stahl Scott Steele Scott Strong Charles Tement Judith Trudel Madhulika Varnna Martin Weiser 丁义江(译) 皇甫少华(译) 丁曙晴(译) | 2013 | 中华胃肠外科杂志2013，16，7： | 70 |
| 2 | Increased expression of tumor necrosis factor-a is associated with advanced colorectal cancer stages显示文摘AIM:To detect the expression of tumor necrosis factor-a(TNF-a)in colorectal cancer(CRC)cells among Saudi patients,and correlate its expression with clinical stages of cancer.METHODS:Archival tissue specimens were collected from 30 patients with CRC who had undergone surgical intervention at King Khalid University Hospital.Patient demographic information,including age and gender,tumor sites,and histological type of CRC,was recorded.To measure TNF-a m RNA expression in CRC,total RNA was extracted from tumor formalin-fixed,paraffinembedded,and adjacent normal tissues.Reverse transcription and reverse transcription polymerase chain reaction were performed.Colorectal tissue microarrays were constructed to investigate the protein expression of TNF-a by immunohistochemistry.RESULTS:The relative expression of TNF-a m RNA in colorectal cancer was significantly higher than that seen in adjacent normal colorectal tissue.High TNF-a gene expression was associated with StageⅢandⅣneoplasms when compared with earlier tumor stages(P=0.004).Eighty-three percent of patients(25/30)showed strong TNF-a positive staining,while only 10%(n=3/30)of patients showed weak staining,and 7%(n=2/30)were negative.We showed the presence of elevated TNF-a gene expression in cancer cells,which strongly correlated with advanced stages of tumor.CONCLUSION:High levels of TNF-a expression could be an independent diagnostic indicator of colorectal cancer,and targeting TNF-a might be a promising prognostic tool by assessment of the clinical stages of CRC. | Omar A Al Obeed Khayal A Alkhayal Abdulmalik Al Sheikh Ahmad M Zubaidi Mansoor-Ali Vaali-Mohammed Robin Boushey James H Mckerrow Maha-Hamadien Abdulla | 2014 | World Journal of Gastroenterology2014，20，48： | 8 |
| 3 | Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors显示文摘 | Fatima Haggar Robin Boushey | 2009 | Clinics in Colon and Rectal Surgery2009，，04： | 6 |
| 4 | Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors显示文摘 | Fatima Haggar Robin Boushey | 2009 | Clinics in Colon and Rectal Surgery2009，，04： | 1 |
| 5 | Laparoscopic repair of parae- sophageal hernias: a Canadian experience 显示文摘 | Robin P Boushey MD Husein M | 2008 | Can J Surg2008，51，5： | 1 |
| 6 | Laparoscopic re-pair of paraesophageal hernias:a Canadian experience显示文摘 | Robin P Boushey MD Husein M | | 0，，05： | 1 |
| 7 | Surgical Stress Promotes the Development of Cancer Metastases by a Coagulation-Dependent Mechanism Involving Natural Killer Cells in a Murine Model显示文摘 | Rashmi Seth Lee-Hwa Tai Theresa Falls Christiano T. de Souza John C. Bell Marc Carrier Harold Atkins Robin Boushey Rebecca A. Auer | 2013 | Annals of Surgery2013，，1： | 1 |
| 8 | Practice Parameters for the Management of Rectal Cancer (Revised)显示文摘 | J. R. T. Monson M. R. Weiser W. D. Buie G. J. Chang J. F. Rafferty W. Donald Buie Janice Rafferty Jose Guillem Robin Boushey George Chang Daniel Feingold Philip Fleshner Jill Genua Kerry Hammond William Harb Samantha Hendren Daniel Herzig Andreas Kaiser D | 2013 | Diseases of the Colon & Rectum2013，，5： | 1 |
| 9 | Glucagon-like p eptide 2 decreases mortality and reduces the severity of indomethacin-induced murine enteritis显示文摘 | Boushey Robin P Bemardo Y | 1999 | Physiol1999，277，40： | 1 |
| 10 | Laparoscopic Total Colectomy: An Evolutionary Experience显示文摘 | Robin P. Boushey Ph.D. M.D. Peter W. Marcello M.D. Guillaume Martel M.D. Lawrence C. Rusin M.D. Patricia L. Roberts M.D. David J. Schoetz M.D | 2007 | Diseases of the Colon & Rectum2007，，10： | 1 |
| 11 | Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors显示文摘 | Fatima Haggar Robin Boushey | 2009 | Clinics in Colon and Rectal Surgery2009，，04： | 1 |
| 12 | Impact of colorectal cancer screening participation in remote northern Canada:A retrospective cohort study显示文摘BACKGROUND Screening provides earlier colorectal cancer(CRC)detection and improves outcomes.It remains poorly understood if these benefits are realized with screening guidelines in remote northern populations of Canada where CRC rates are nearly twice the national average and access to colonoscopy is limited.AIM To evaluate the participation and impact of CRC screening guidelines in a remote northern population.METHODS This retrospective cohort study included residents of the Northwest Territories,a northern region of Canada,age 50-74 who underwent CRC screening by a fecal immunohistochemical test(FIT)between January 1,2014 to March 30,2019.To assess impact,individuals with a screen-detected CRC were compared to clinically-detected CRC cases for stage and location of CRC between 2014-2016.To assess participation,we conducted subgroup analyses of FIT positive individuals exploring the relationships between signs and symptoms of CRC at the time of screening,wait-times for colonoscopy,and screening outcomes.Two sample Welch t-test was used for normally distributed continuous variables,Mann-Whitney-Wilcoxon Tests for data without normal distribution,and Chi-square goodness of fit test for categorical variables.A P value of<0.05 was considered to be statistically significant.RESULTS 6817 fecal tests were completed,meaning an annual average screening rate of 25.04%,843(12.37%)were positive,629 individuals underwent a follow-up colonoscopy,of which,24.48%had advanced neoplasia(AN),5.41%had CRC.There were no significant differences in stage,pathology,or location between screen-detected cancers and clinically-detected cancers.In assessing participation and screening outcomes,we observed 49.51%of individuals referred for colonoscopy after FIT were ineligible for CRC screening,most often due to signs and symptoms of CRC.Individuals were more likely to have AN if they had signs and symptoms of cancer at the time of screening,waited over 180 d for colonoscopy,or were indigenous[respectively,estimated RR 1.1895%CI of RR(0.89-1.59)];RR 1.523(CI:1.035,2.240);RR 1.722(CI:1.165,2.547)].CONCLUSION Screening did not facilitate early cancer detection but facilitated higher than anticipated AN detection.Signs and symptoms of CRC at screening,and long colonoscopy wait-times appear contributory. | Heather A Smith Andrew D Scarffe Nicole Brunet Cait Champion Kami Kandola Alisha Tessier Robin Boushey Craig Kuziemsky | 2020 | World Journal of Gastroenterology2020，26，48： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员