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95篇 您的检索式:作者名="George Chang"
    题名 作者 年代 出处 被引量
1肛裂临床诊治指南(第三次修订)显示文摘“美国结直肠外科医师协会(American Societyof ColonandRectal Surgeons.ASCRS)”(协会)致力于推进结直肠和肛门疾病的相关理论以及预防和诊疗水平的提高,给患者提供优质的医疗服务。“标准委员会”由协会中在结直肠外科方面有显著专长的成员组成。该委员会的建立是为了引领国际结直肠和肛门疾病诊治的发展,以建立具有循证医学证据的临床诊疗指南。指南是涵盖性的,非指令性的,目的是为临床决策提供信息,而非具体的治疗方法。指南适用于所有相关的医护人员以及希望得到相应指南中疾病的相关诊治信息的患者。Farshid Araghizadeh ~ Robin Boushey Sridhar Chalasani George Chang Robert Cima Gary Dunn Daniel Feingold Philip Fleshner Daniel Geisler Jill Genua Sharon Gregorcyk Daniel Herzig Andreas Kaiser Ravin Kumar David Larson Steven Mills John Monson P. Terry Phang Feza Remzi David Rivadeneira Howard Ross Peter Senatore Elin Sigurdson Thomas Stahl Scott Steele Scott Strong Charles Tement Judith Trudel Madhulika Varnna Martin Weiser 丁义江(译) 皇甫少华(译) 丁曙晴(译) 2013中华胃肠外科杂志2013,16,7:70
2A community-derived classification for extant lycophytes and ferns显示文摘发展史长通知了蕨类植物分类。当我们推断进化的树的能力改善了,针对认出生来的组的分类变得逐渐地预兆、稳定。这里,我们为 lycophytes 和蕨纲植物提供一个现代、全面分类,在下面,利用一条基于社区的途径类水平。我们 monophyly 用作主要标准让 taxa,而且目的识别保存两个广泛地被接受的存在 taxa 和界限并且与我们蕨类植物发展史的理解一致。总共,这个分类对待一在 337 个类, 51 个家庭, 14 目,和二个班估计了 11  916 种类。这个分类没在 lycophyte 和蕨纲植物上作为最后的词被打算分类,而是当前的假设的概括陈述,源于最好的可得到的数据并且在问题由熟悉植物的那些大多数塑造了。我们希望它将在蕨类植物上为最近的文学的那些想要的参考用作一个资源发展史和分类,为指导未来调查的一个框架,和推进讲话的刺激。Eric Schuettpelz Harald Schneider Alan R. Smith Peter Hovenkamp Jefferson Prado Germinal Rouhan Alexandre Salino Michael Sundue Thafs Elias Almeida Barbara Parris Emily B. Sessa Ashley R. Field Andre Luis de Gasper Carl J. Rothfels Michael D. Windham Marcus Lehnert Benjamin Dauphin Atsushi Ebihara Samuli Lehtonen Pedro Bond Schwartsburd Jordan Metzgar Li-Bing Zhang Li-Yaung Kuo Patrick J. Brownsey Masahiro Kato Marcelo Daniel Arana Francine C. Assis Michael S. Barker David S. Barrington Ho-Ming Chang Yi-Han Chang Yi-Shan Chao Cheng-Wei Chen De-Kui Chen Wen-Liang Chiou Vinicius Antonio de Oliveira Dittrich Yi-Fan Duan Jean-Yves Dubuisson Donald R. Farrar Susan Fawcett Jose Maria Gabriel y Galan Luiz Armando de Araujo Goes-Neto Jason R. Grant Amanda L. Grusz Christopher Haufler Warren Hauk Hai He Sabine Hennequin Regina Yoshie Hirai Layne Huiet Michael Kessler Petra Korall Paulo H. Labiak Anders Larsson Blanca Leen Chun-Xiang Li Fay-Wei Li Melanie Link-Perez Hong-Mei Liu Ngan Thi Lu Esteban I. Meza-Torres Xin-Yuan Miao Robbin Moran Claudine Massi Mynssens Nathalie Nagalingum Benjamin Ollgaard Alison M. Paul Jovani B. de S. Pereira Leon R. Perrie Monica Ponce Tom A. Ranker Christian Schulz Wataru Shinohara Alexander Shmakov Erin M. Sigel Filipe Soares de Souza Lana da Silva Sylvestre Weston Testo Luz Amparo Triana-Moreno Chie Tsutsumi Hanna Tuomisto IvAn A. Valdespino Alejandra Vasco Raquel Stauffer Viveros Alan Weakley Ran Wei Stina Weststrand Paul G. Wolf George Yatskievych Xiao-Gang Xu Yue-Hong Yan Liang Zhang Xian-Chun Zhang Xin-Mao Zhou 2016Journal of Systematics and Evolution2016,54,6:44
3帕博利珠单抗单用或与放疗联用治疗转移性非小细胞肺癌:两个随机试验的汇总分析显示文摘背景放疗可以提高整个机体对免疫治疗的应答。在Ⅱ期PEMBRO-RT研究和Ⅰ/Ⅱ期MDACC研究中,患有转移性非小细胞肺癌(NSCLC)的患者被随机分配入组,接受免疫治疗(帕博利珠单抗)+放疗联合疗法,或免疫治疗单一疗法。当上述2个研究单独分析时,联合疗法组显示出潜在获益。由于每个研究的样本量较小,缓解率和结局并未显示出统计学意义,然而却有显著的临床获益。因此,本研究进行汇总分析,来判断放疗是否会改善转移性NSCLC患者的免疫治疗应答。方法PEMBRO-RT和MDACC研究纳入标准:患者年龄≥18岁,患有转移性NSCLC,且有≥1处未经放疗照射的病灶,以便进行射野外应答监测。PEMBRO-RT研究纳入曾接受过化疗患者,MDACC研究纳入曾接受过治疗或新诊断患者。2个研究中的患者均未接受过免疫治疗。在PEMBRO-RT研究中患者被等比例随机分配入组,并根据吸烟状态进行分层(分为<10年组和≥10年组)。MDACC研究的患者根据放疗计划可行性被等比例随机分配入2个受试组。由于联合治疗组的干预本质,每个研究中的放疗均不适用盲法。在2个研究中,不论是否进行放疗,均静脉滴入帕博利珠单抗(每3周200 mg)。在PEMBRO-RT研究中,在放疗(24 Gy 3次分割照射)结束后1周给予第1剂帕博利珠单抗。在MDACC研究中,在第1次放疗(50 Gy 4次分割照射或45 Gy 15次分割照射)同时给予帕博利珠单抗。仅检测未经照射病灶的应答。本研究的终点为最佳射野外(远隔)应答率(ARR)、最佳射野外疾病控制率(ACR)、12周时ARR、12周时ACR、无进展生存期(PFS)和总生存期(OS)。2个研究的意向治疗(ITT)人群均纳入分析。PEMBRO-RT研究(NCT02492568)和MDACC研究(NCT02444741)均在ClinicalTrials.gov上注册。发现纳入148例患者,76例接受帕博利珠单抗治疗,72例接受帕博利珠单抗+放疗治疗。所有患者随访时间中位数为33个月[四分位距(IQR):32.4~33.6]。148例患者中124例(84%)组织学特征为非鳞癌,111例(75%)患者曾经接受过化疗。组间没有基线特征差异,包括PD-L1表达状态和转移灶体积。最常见的照射部位为肺转移灶(39%,28/72)、胸腔内淋巴结(21%,15/72)和非原发灶(17%,12/72)。帕博利珠单抗组和联合治疗组的最佳ARR分别为19.7%(15/76)和41.7%(30/72),OR=2.96,95%CI:1.42~6.20,P=0.0039;最佳ACR分别为43.4%(33/76)和65.3%(47/72),OR=2.51,95%CI:1.28~4.91,P=0.0071;PFS中位数分别为4.4(IQR:2.9~5.9)和9.0个月(IQR:6.8~11.2),HR=0.67,95%CI:0.45~0.99,P=0.045;OS中位数分别为8.7(IQR:6.4~11.0)和19.2个月(IQR:14.6~23.8),OR=0.67,95%CI:0.54~0.84,P=0.0004。在汇总分析中没有发现新的安全问题。解读帕博利珠单抗免疫疗法+放疗显著提高转移性NSCLC患者的应答和改善治疗结局。这些结果需要在三期临床试验中进行验证。陈大卫(翻译) 于金明(校对) Willemijn S M E Theelen Vivek Verma Brian P Hobbs Heike M U Peulen Joachim G J V Aerts Idris Bahce Anna Larissa N Niemeijer Joe Y Chang Patricia M de Groot Quynh-Nhu Nguyen Nathan I Comeaux George R Simon Ferdinandos Skoulidis Steven H Lin Kewen He Roshal Patel John Heymach Paul Baas James W Welsh 2021中华肿瘤防治杂志2021,28,24:49
4Petawatt and exawatt class lasers worldwide显示文摘In the 2015 review paper‘Petawatt Class Lasers Worldwide’a comprehensive overview of the current status of highpower facilities of>200 TW was presented.This was largely based on facility specifications,with some description of their uses,for instance in fundamental ultra-high-intensity interactions,secondary source generation,and inertial confinement fusion(ICF).With the 2018 Nobel Prize in Physics being awarded to Professors Donna Strickland and Gerard Mourou for the development of the technique of chirped pulse amplification(CPA),which made these lasers possible,we celebrate by providing a comprehensive update of the current status of ultra-high-power lasers and demonstrate how the technology has developed.We are now in the era of multi-petawatt facilities coming online,with 100 PW lasers being proposed and even under construction.In addition to this there is a pull towards development of industrial and multi-disciplinary applications,which demands much higher repetition rates,delivering high-average powers with higher efficiencies and the use of alternative wavelengths:mid-IR facilities.So apart from a comprehensive update of the current global status,we want to look at what technologies are to be deployed to get to these new regimes,and some of the critical issues facing their development.Colin N.Danson Constantin Haefner Jake Bromage Thomas Butcher Jean-Christophe FChanteloup Enam A.Chowdhury Almantas Galvanauskas Leonida A.Gizzi Joachim Hein David I.Hillier Nicholas W.Hopps Yoshiaki Kato Efim A.Khazanov Ryosuke Kodama Georg Korn Ruxin Li Yutong Li Jens Limpert Jingui Ma Chang Hee Nam David Neely Dimitrios Papadopoulos Rory R.Penman Liejia Qian Jorge J.Rocca andrey A.Shaykin Craig W.Siders Christopher Spindloe Sándor Szatmári Raoul M.G.M.Trines Jianqiang Zhu Ping Zhu Jonathan D.Zuegel 2019High Power Laser Science and Engineering2019,7,3:33
5Tetramethylpyrazine suppresses HIF-1α,TNF-α,and activated caspase-3 expression in middle cerebral artery occlusion-induced brain ischemia in rats显示文摘瞄准:检验详细机制位于禁止的效果 oftetramethylpyrazine (TMPZ ) 下面在煽动性并且 apoptotic 回答在 rats.Methods 由中间的服的 arteryocclusion (MCAO ) 导致了:在老鼠的导致 MCAO 的焦点的服的局部缺血在 thisstudy.The 被使用组织缺氧可诱导的 factor-1alpha (HIF-1alpha ) , caspase-3 的激活,和在 ischemic 区域的 TNF-alpha mRNAtranscription 被 immunoblotting andRT-PCR 检测, respectively.Anti 氧化的活动用 thiobarbituric acid-reactivesubstance (TBARS ) 被调查老鼠大脑 homogenate preparations.Results 的测试:我们显示出溶剂的梗塞区域的 statisticalresults --并且 TMPZ ( 20 mg/kg )在在在有 TMPZ ( 20 mg/kg )的 rats.Treatment 的 导致MCAO 的焦点的服的局部缺血的正面的杆显著地减少了的各种各样的 distancesfrom 对待组在所有区域的梗塞区域,在特别,第三显著地与 ischemic regions.These expressionswere 的 caspase-3 ,以及 TNF-alpha 抄写的 HIF-1alpha 和 theactivation 的增加被联系到 导致fifthsections.MCAO 的焦点的服的局部缺血我 neuroprotective effectof TMPZ 可以至少被 EOF-1alpha 和 TNF-alphaactivations 的抑制的部分调停,由 apoptosis 形成(活跃 caspase-3 )的抑制列在后面,在 ischemia-reperfusion 大脑 injury.Thus 在梗塞体积导致 areduction , TMPZ 处理 mayrepresent 在 ischemia-reperfusionbrain 降低风险或改善功能的一条理想的途径损害相关的混乱。Yi CHANG George HSIAO Seu-hwa CHEN Yi-cheng CHEN Jiing-han LIN Kuang-hung LIN Duen-suey CHOU Joen-rong SHEU 2007Acta Pharmacologica Sinica2007,28,3:30
6智能压实测量值的发展方向显示文摘背景智能压实(Intelligent Compaction,简称IC)是一种基于压实机械、可提高压实质量的控制技术。具有智能压实技术的振动压路机装配有基于加速度传感器的测量系统、平板电脑、高精度全球定位系统(GPS)和红外温度传感器。智能压实可以改进各种道路材料的压实质量控制,包括粗粒土、黏性土、基层材料和沥青材料。基于加速度传感器的测量系统是20世纪80年代早期发明的智能压实技术(连续压实控制)的核心,今天仍在发展之中。徐光辉 George Chang 2018筑路机械与施工机械化2018,35,4:21
7智能压实技术的研究进展显示文摘自从1976年瑞典提出利用振动压路机碾压过程中动态响应信号的畸变程度进行压实质量检测的压实计方法以来,这类以振动压路机为工具的检测与控制方法在欧洲得到了很好的发展,并于20世纪90年提出连续压实控制(CCC)的概念。吴金海 雒泽华 徐光辉 田波 George chang 2017筑路机械与施工机械化2017,34,1:16
82-D eddy resolving simulations of flow past a circular array of cylindrical plant stems显示文摘In the present study, 2-D large eddy simulations(LES) are conducted for flow past a porous circular array with a solid volume fraction(SVF) of 8.8%, 15.4% and 21.5%. Such simulations are relevant to understanding flow in natural streams and channels containing patches of emerged vegetation. In the simulations discussed in the paper, the porous cylinder of diameter D contains a variable number of identical solid circular cylinders(rigid plant stems) of diameter d= 0.048 D. Most of the simulations are conducted at a Reynolds number of 2 100 based on the diameter D and the velocity of the steady uniform incoming flow. Though in all cases wake billows are shed in the regions where the separated shear layers(SSLs) forming on the sides of the porous cylinder interact, the effect of these wake billows on the mean drag is different. While in the high SVF case(21.5%), the total drag force oscillates quasi-regularly in time, similar to the canonical case of a large solid cylinder, in the cases with a lower SVF the shedding of the wake billows takes place sufficiently far from the cylinder such that the unsteady component of the total drag force is negligible. The mean amplitude of the oscillations of the drag force on the individual cylinders is the largest in a streamwise band centered around the center of the porous cylinder, where the wake to wake interactions are the strongest. In all cases the maximum drag force on the individual cylinders is the largest for the cylinders directly exposed to the flow, but this force is always smaller than the one induced on a small isolated cylinder and the average magnitude of the force on the cylinders directly exposed to the flow decreases monotonically with the increase in the SVF. Predictions of the global drag coefficients, Strouhal numbers associated with the wake vortex shedding and individual forces on the cylinders in the array from the present LES are in very good agreement with those of 2-D direct numerical simulations conducted on finer meshes, which suggests LES is a better option to numerically investigate flow in channels containing canopy patches, given that LES is computationally much less expensive than DNS at high Reynolds number. To prove this point, the paper also discusses results of 2-D LES conducted at a much higher Reynolds number, where the near-wake flow is strongly turbulent. For the higher Reynolds number cases, where the influence of the turbulence model is important, the effect of the sub-grid scale model and the predictive capabilities of the unsteady Reynolds averaged Navier-Stokes(RANS) approach to predict flow past porous cylinders are discussed.Kyoungsik Chang George Constantinescu Sanghyun Park 2018Journal of Hydrodynamics2018,30,2:8
9It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis显示文摘Background There is concern that blood pressure(BP)lowering in acute stroke may compromise cerebral perfusion and worsen outcome in the presence of carotid stenosis.We assessed the effect of glyceryl trinitrate(GTN)in patients with carotid stenosis using data from the Efficacy of Nitric Oxide in Stroke(ENOS)Trial.Methods ENOS randomised 4011 patients with acute stroke and raised systolic BP(140-220 mm Hg)to transdermal GTN or no GTN within 48 hours of onset.Those on prestroke antihypertensives were also randomised to stop or continue their medication for 7 days.The primary outcome was the modified Rankin Scale(mRS)at day 90.Ipsilateral carotid stenosis was split:<30%;30-<50%;50-<70%;≥70%.Data are ORs with 95%CIs adjusted for baseline prognostic factors.results 2023(60.5%)ischaemic stroke participants had carotid imaging.As compared with<30%,≥70%ipsilateral stenosis was associated with an unfavourable shift in mRS(worse outcome)at 90 days(OR 1.88,95%CI 1.44 to 2.44,p<0.001).Those with≥70%stenosis who received GTN versus no GTN had a favourable shift in mRS(OR 0.56,95%CI 0.34 to 0.93,p=0.024).In those with 50-<70%stenosis,continuing versus stopping prestroke antihypertensives was associated with worse disability,mood,quality of life and cognition at 90 days.Clinical outcomes did not differ across bilateral stenosis groups.Conclusions Following ischaemic stroke,severe ipsilateral carotid stenosis is associated with worse functional outcome at 90 days.GTN appears safe in ipsilateral or bilateral carotid stenosis,and might improve outcome in severe ipsilateral carotid stenosis.Jason P Appleton Lisa J Woodhouse Andrew Belcher Daniel Bereczki Eivind Berge Valeria Caso Hui Meng Chang Hanne K Christensen Ronan Collins John Gommans Ann C Laska George Ntaios Serefnur Ozturk Gillian M Sare Szabolcs Szatmari Yongjun Wang Joanna M Wardlaw Nikola Sprigg Philip M Bath for the ENOS investigators 2019Stroke & Vascular Neurology2019,4,1:6
10Clinical applications, limitations and future role of transient elastography in the management of liver disease显示文摘Transient elastography(TE) is a reliable tool for the non-invasive assessment of liver fibrosis in routine clinical practice. TE is currently approved for use in Europe, Asia and the United States. The widespread adoption of this technology is certain to increase the use of TE worldwide. Although TE has been well validated in chronic viral hepatitis, its clinical role in other liver diseases remains less clear. The advent of new treatment for chronic hepatitis C and emerging prevalence of non-alcoholic steatohepatitis raises new questions on the role of TE in current clinical practice. This review aims to examine the clinical applications, limitations and future role of TE in current clinical practice in light of the changing epidemiology of liver diseases and new clinical management paradigms. In current clinical practice, TE is the most accurate noninvasive method for diagnosis of liver cirrhosis. TE is useful to rule out fibrosis and cirrhosis but does not have sufficient accuracy to discern between various stages of fibrosis. The clinical role of TE has evolved from cross-sectional point-in-time assessment of fibrosis and cirrhosis to the more relevant role of prediction of vital clinical end-points. This provides clinicians with the ability to modify treatment strategies based on the information provided by TE. TE has evolved over the past decade to become an essential tool to assist the clinician in the management of chronic liver disease.Pik Eu Chang George Boon-Bee Goh Jing Hieng Ngu Hiang Keat Tan Chee Kiat Tan 2016World Journal of Gastrointestinal Pharmacology and Therapeutics2016,7,1:5
11Barcelona Clinic Liver Cancer outperforms Hong Kong Liver Cancer staging of hepatocellular carcinoma in multiethnic Asians: Real-world perspective显示文摘AIM To compare the Barcelona Clinic Liver Cancer(BCLC) and Hong Kong Liver Cancer(HKLC) classification systems when applied to HCC patients from the largest tertiary-level centre in Singapore.METHODS One thousand two hundred and seventy hepatocellular carcinoma(HCC) patients prospectively enrolled in a tertiary-level centre registry in Singapore since 1988 were studied. Patients were grouped into their respective BCLC and HKLC stages. Data such as demography, aetiology of HCC and type of treatment were collected. Survival data was based on census with the National Registry of Births and Deaths on 31 st October 2015. Statistical analyses were done using SPSS version 21(Chicago, IL, United States). Survival analyses were done by the Kaplan-Meier method. Differences in survival rates were compared using the log-rank test.RESULTS The median age at presentation was 63 years(range 13-94); male 82.4%; Chinese 89.4%, Malay 7.1%, Indian, 2.8%. Hepatitis B was the predominant aetiology(75.0%; Hepatitis C 7.2%, Hepatitis B and C co-infection 3.8%, non-viral 14.0%). Both BCLC and HKLC staging systems showed good separation with overall log rank test confirming significant survival differences between stages in our cohort(P < 0.001). 206 out of the 240 patients(85.8%) assigned for curative treatment by the BCLC treatment algorithm received curative therapy for HCC [Stage 0 93.2%(68/73); Stage A 82.6%(138/167)]. In contrast, only 341/558(61.1%) patients received curative treatment despite being assigned for curative treatment by the HKLC treatment algorithm [Stage Ⅰ 72.7%(264/363); Stage Ⅱ 40.2%(66/164); Stage Va 35.5%(11/31)]. Patients who were assigned to curative treatment by HKLC but did not receive curative treatment had significantly poorer ECOG(P < 0.001), higher ChildPugh status(P < 0.001) and were older(median age 66 vs 61, P < 0.001) than those who received curative therapy. Median overall survival in patients assigned to curative treatment groups by BCLC and HKLC were 6.1 and 2.6 years respectively(P < 0.001). When only patients receiving curative treatment were analyzed, BCLC still predicted overall median survival better than HKLC(7.1 years vs 5.5 years, P = 0.037). CONCLUSION BCLC performs better than HKLC in our multiethnic Asian population in allocating patients to curative treatment in a real-life situation as well as in predicting survival.James Weiquan Li Boon-Bee George Goh Pik-Eu Chang Chee-Kiat Tan 2017World Journal of Gastroenterology2017,23,22:4
12Low serum albumin predicts early mortality in patients with severe hypoxic hepatitis显示文摘AIM To evaluate the incidence, etiology, and predictors of mortality of severe hypoxic hepatitis. METHODS We used computerized patient records to identify consecutive cases of severe hypoxic hepatitis admitted to a tertiary hospital in Singapore over a one-year period. We defined severe hypoxic hepatitis as elevation of serum transaminases more than 100 times upper limit of normal in the clinical setting of cardiac, circulatory or respiratory failure after exclusion of other causes of hepatitis. We used multivariable regression analysis to determine predictors for mortality. RESULTS We identified 75 cases of severe hypoxic hepatitis out of 71380 hospital admissions over one year, providing an incidence of 1.05 cases per 1000 admissions. Median age was 65 years(range 19-88); 57.3% males. The most common etiologies of severe hypoxic hepatitis were acute myocardial infarction and sepsis. Fifty-three patients(71%) died during the hospitalization. The sole independent predictive factor for mortality was serum albumin measured at the onset of severe hypoxic hepatitis. Patients with low serum albumin of less than 28 g/L have more than five-fold increase risk of death(OR = 5.39, 95%CI: 1.85-15.71).CONCLUSION Severe hypoxic hepatitis is uncommon but has a high mortality rate. Patients with low serum albumin are at highest risk of death.Pik-Eu Chang Boon-Bee George Goh Victoria Ekstrom Ming-Liang Ong Chee-Kiat Tan 2017World Journal of Hepatology2017,9,22:3
13The Cost-Effectiveness of Neoadjuvant Chemoradiation is Superior to a Surgery-First Approach in the Treatment of Pancreatic Head Adenocarcinoma显示文摘Daniel E. Abbott Ching-Wei David Tzeng Ryan P. Merkow Scott B. Cantor George J. Chang Matthew Harold Katz David J. Bentrem Karl Y. Bilimoria Christopher H. Crane Gauri R. Varadhachary James L. Abbruzzese Robert A. Wolff Jeffrey E. Lee Douglas B. Evans Jas 2013Annals of Surgical Oncology2013,,3:3
14Long-term Therapy With Adefovir Dipivoxil for HBeAg-Negative Chronic Hepatitis B for up to 5 Years显示文摘Stephanos J. Hadziyannis Nicolaos C. Tassopoulos E. Jenny Heathcote Ting–Tsung Chang George Kitis Mario Rizzetto Patrick Marcellin Seng Gee Lim Zachary Goodman Jia Ma Carol L. Brosgart Katyna Borroto–Esoda Sarah Arterburn Steven L. Chuck 2006Gastroenterology2006,,6:3
15Spatial Analysis of People Living with HIV/AIDS Transmitted Through Commercial Heterosexual Contact or Non-Marital Non-Commercial Heterosexual Contact—China,2018显示文摘Summary What is already known about this topic?Significant changes in human immunodeficiency virus(HIV)transmission modes have occurred in China,and the proportion of heterosexual transmission increased in recent years.What is added by this report?The proportions of diverse transmission routes and subgroups of heterosexual transmission were analyzed by provincial-level administrative divisions(PLADs).Zhilong Dong Xiaohong Pan Chang Cai Qianqian Qin George F.Gao Fan Lyu 2021China CDC weekly2021,3,15:3
16Long-term Therapy With Adefovir Dipivoxil for HBeAg-Negative Chronic Hepatitis B for up to 5 Years显示文摘Stephanos J. Hadziyannis Nicolaos C. Tassopoulos E. Jenny Heathcote Ting–Tsung Chang George Kitis Mario Rizzetto Patrick Marcellin Seng Gee Lim Zachary Goodman Jia Ma Carol L. Brosgart Katyna Borroto–Esoda Sarah Arterburn Steven L. Chuck 2006Gastroenterology2006,,6:2
17Clinical Significance of Acellular Mucin in Rectal Adenocarcinoma Patients With a Pathologic Complete Response to Preoperative Chemoradiation显示文摘Kerrington D. Smith Dongfeng Tan Prajnan Das George J. Chang Kiran Kattepogu Barry W. Feig John M. Skibber Miguel A. Rodriguez-Bigas 2010Annals of Surgery2010,,2:2
18Transactivation of miR-34a by p53 Broadly Influences Gene Expression and Promotes Apoptosis显示文摘Tsung-Cheng Chang Erik A. Wentzel Oliver A. Kent Kalyani Ramachandran Michael Mullendore Kwang Hyuck Lee Georg Feldmann Munekazu Yamakuchi Marcella Ferlito Charles J. Lowenstein Dan E. Arking Michael A. Beer Anirban Maitra Joshua T. Mendell 2007Molecular Cell2007,,:2
19Is the 1-cm Rule of Distal Bowel Resection Margin in Rectal Cancer Based on Clinical Evidence? A Systematic Review显示文摘Krzysztof Bujko MD PhD Andrzej Rutkowski MD PhD George J. Chang MD MS Wojciech Michalski MSc Ewa Chmielik MD PhD Jerzy Kusnierz MD PhD 2012Annals of Surgical Oncology2012,,3:2
20Proteomics Analysis Identifies Molecular Targets Related to Diabetes Mellitus- associated Bladder Dysfunction显示文摘Elizabeth Yohannes Jinsook Chang George J Christ 2008Molecular & Cellular Proteomics2008,7,:1
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