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| 1 | SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells显示文摘Intercellular adhesion molecule-1 (ICAM-1) plays an important role in the recruitment of leukocytes to the endothelium, which causes inflammation and initiation of atherosclerosis. We have previously shown that endothelium-specific over-expression of class III deacetylase SIRT1 decreases atherosclerosis. We therefore addressed the hypothesis that SIRT1 suppresses ICAM-1 expression in the endothelial cells. Here, we found that expression of SIRT1 and ICAM-1 was significantly induced by PMA and ionomycin (PMA/Io) in human umbilical vein endothelial cells (HUVECs). Adenovirus-mediated over-expression of SIRT1 significantly inhibited PMA/Io-induced ICAM-1 expression in HUVECs. Knockdown of SIRT1 by RNA interference (RNAi) resulted in increased expression of ICAM-1 in HUVECs. Luciferase report assay showed that over-expression of SIRT1 suppressed ICAM-1 promoter activity both in basic and in PMA/Io-induced conditions. We further found that SIRT1 was involved in transcription complex binding on the ICAM-1 promoter by chromatin immunoprecipitation (ChIP) assays. Furthermore, SIRT1 RNAi increased NF-κB p65 binding ability to the ICAM-1 promoter by ChIP assays. Overall, these data suggests that SIRT1 inhibits ICAM-1 expression in endothelial cells, which may contribute to its anti-atherosclerosis effect. | JIA YuYan GAO Peng CHEN HouZao WAN YanZhen ZHANG Ran ZHANG ZhuQin YANG RuiFeng WANG Xu XU Jing LIU DePei | 2013 | Science China(Life Sciences)2013，56，1： | 9 |
| 2 | Activation of STAT3 stimulates AHSP expression in K562 cells显示文摘Studies on the chaperone proteinα-hemoglobin stabilizing protein(AHSP)reveal that abundant AHSP in erythroid cells enhance the cells’tolerance to oxidative stress imposed by excessα-hemoglobin in pathological conditions.However,the potential intracellular modulation of AHSP expression itself in response to oxidative stress is still unknown.The present study examined the effect and molecular mechanism of STAT3,an oxidative regulator,on the expression of AHSP.AHSP expression increased in K562 cells upon cytokine IL-6-induced STAT3 activation and decreased in STAT3 knock-down K562 cells.Regulation of AHSP in oxidative circumstance was then examined inα-globin-overloaded K562 cells,and real-time PCR showed strengthened expression of both AHSP and STAT3.ChIP analysis showed binding of STAT3 to AHSP promoter and binding was significantly augmented with IL6 stimulation and uponα-globin overexpression.Dual luciferase reporter assays of the wildtype and mutated SB3 element,an IL-6RE site,in the AHSP promoter in K562 cells highlighted the direct regulatory effect of STAT3 on AHSP gene.Finally,direct binding of STAT3 to SB3 site of AHSP promoter was confirmed with EMSA assays.Our work reveals an adaptive AHSP regulation mediated by the redox-sensitive STAT3 signaling pathway,and provides clues to the therapeutic strategy for AHSP enhancement. | CAO Cong ZHAO GuoWei YU Wei XIE XueMin WANG WenTian YANG RuiFeng LV Xiang LIU DePei | 2014 | Science China(Life Sciences)2014，57，5： | 5 |
| 3 | A viral protein orchestrates rice ethylene signaling to coordinate viral infection and insect vector-mediated transmission显示文摘Arthropod-borne viruses cause serious threats to human health and global agriculture by rapidly spreading via insect vectors. Southern rice black-streaked dwarf virus (SRBSDV) is the most damaging rice-infecting virus that is frequently transmitted by planthoppers. However, the molecular mechanisms underlying its propagation in the host plants and epidemics in the field are largely unknown. Here, we showed that the SRBSDV-encoded P6 protein is a key effector that regulates rice ethylene signaling to coordinate viral infection and transmission. In early SRBSDV infection, P6 interacts with OsRTH2 in the cytoplasm to activate ethylene signaling and enhance SRBSDV proliferation;this also repels the insect vector to reduce infestation. In late infection, P6 enters the nucleus, where it interacts with OsEIL2, a key transcription factor of ethylene signaling. The P6-OsEIL2 interaction suppresses ethylene signaling by preventing the dimerization of OsEIL2, thereby facilitating viral transmission by attracting the insect vector. Collectively, these findings reveal a novel molecular mechanism by which an arbovirus modulates the host defense system to promote viral infection and transmission. | Yaling Zhao Xue Cao Weihua Zhong Shunkang Zhou Zhanbiao Li Hong An Xiahua Liu Ruifeng Wu Surakshya Bohora Yan Wu Zhenyi Liang Jiahao Chen Xin Yang Guohui Zhou Tong Zhang | 2022 | Molecular Plant2022，15，4： | 4 |
| 4 | Fabrication of sharp silicon hollow microneedles by deep-reactive ion etching towards minimally invasive diagnostics显示文摘Microneedle technologies have the potential for expanding the capabilities of wearable health monitoring from physiology to biochemistry.This paper presents the fabrication of silicon hollow microneedles by a deep-reactive ion etching(DRIE)process,with the aim of exploring the feasibility of microneedle-based in-vivo monitoring of biomarkers in skin fluid.Such devices shall have the ability to allow the sensing elements to be integrated either within the needle borehole or on the backside of the device,relying on capillary filling of the borehole with dermal interstitial fluid(ISF)for transporting clinically relevant biomarkers to the sensor sites.The modified DRIE process was utilized for the anisotropic etching of circular holes with diameters as small as 30μm to a depth of>300μm by enhancing ion bombardment to efficiently remove the fluorocarbon passivation polymer.Afterward,isotropic wet and/or dry etching was utilized to sharpen the needle due to faster etching at the pillar top,achieving tip radii as small as 5μm.Such sharp microneedles have been demonstrated to be sufficiently robust to penetrate porcine skin without needing any aids such as an impact-insertion applicator,with the needles remaining mechanically intact after repetitive penetrations.The capillary filling of DRIE-etched through-wafer holes with water has also been demonstrated,showing the feasibility of use to transport the analyte to the target sites. | Yan Li Hang Zhang Ruifeng Yang Yohan Laffitte Ulises Schmill Wenhan Hu Moufeed Kaddoura Eric J.M.Blondeel Bo Cui | 2019 | Microsystems & Nanoengineering2019，5，1： | 4 |
| 5 | The influence of intimacy on the ’iterative reactions’ during OX-ZEO process for aromatic production显示文摘The oxide-zeolite process provides a promising way for one-step production of aromatics from syngas,whereas the reasons for the dramatic effect of intimacy between oxide and zeolite in the composite catalyst on the product selectivity are still unclear. In order to explore the optimal intimacy and the essential influence factors, ZnCrOxcombined with ZSM-5 are employed to prepare the composite catalysts with different distances between the two components by changing the mixing methods. An aromatic selectivity of 74%(with CO conversion to be 16%) is achieved by the composite catalyst when the intimacy is in the range of nanometer. A so-called ‘iterative reactions’ mechanism of intermediates over oxides is then proposed and studied: the intermediate chemical can undergo a hydrogenation reaction on oxide.So the shorter the intermediates stay on oxide, the more of chance for C-C coupling takes place on zeolite to form aromatics. Moreover, the aero-environments of reaction is found to impact on the extent of iterative reaction as well. Therefore, when the intimacy between the two components changes, the extent of iterative reactions vary, resulting in alteration of product distribution. This work provides new insight in understanding the mechanisms during the complex process of OX-ZEO composite catalysis and sheds light to the design of a high-yield catalyst for synthetization of aromatics from syngas. | Xiaoli Yang Ting Sun Junguo Ma Xiong Su Ruifeng Wang Yaru Zhang Hongmin Duan Yanqiang Huang Tao Zhang | 2019 | Journal of Energy Chemistry2019，28，8： | 4 |
| 6 | Non-Cooperative Differential Game Based Energy Consumption Control for Dynamic Demand Response in Smart Grid显示文摘In this paper, we conduct research on the dynamic demand response problem in smart grid to control the energy consumption. The objective of the energy consumption control is constructed based on differential game, as the dynamic of each users’ energy state in smart gird can be described based on a differential equation. Concept of electricity sharing is introduced to achieve load shift of main users from the high price hours to the low price hours. Nash equilibrium is given based on the Hamilton equation and the effectiveness of the proposed model is verified based on the numerical simulation results. | Manxi Wang Haitao Xu Shengsong Yang Lifeng Yang Ruifeng Duan Xianwei Zhou | 2019 | China Communications2019，16，8： | 4 |
| 7 | Effects of Solvent Molecules on the Interlayer Spacing of Graphene Oxide显示文摘Graphene oxide(GO) contains numerous functional groups that facilitate the intercalation of polar solvents. The properties and applications of GO are closely related to its interlayer spacing. We report on the changes in the interlayer spacing of GO after the adsorption of water molecules and the polar organic solvents C_2H_6O_2(EG), C_3H_7NO(DMF), C_5H_9NO(NMP). Experiments were conducted to investigate the variations in the functional groups and structure of GO after solvent adsorption, and they play a vital role in modeling and verifying the results of molecular dynamics simulation. The most stable GO structures are obtained through molecular dynamics simulation. The expansion of the interlayer spacing of GO after the adsorption of monolayer solvent molecules corresponds to the minimum three-dimensional size of the solvent molecules. The spatial arrangement of solvent molecules also contributes to the changes in interlayer spacing. Most adsorbed molecules are oriented parallel to the carbon plane of GO. However, as additional molecules are adsorbed into the interlaminations of GO, the adsorbed molecules are oriented perpendicular to the carbon plane of GO, and a large space forms between two GO interlayers. In addition, the role of large molecules in increasing interlayer spacing becomes more crucial than that of water molecules in the adsorption of binary solvent systems by GO. | Liyan Liu Ruifeng Zhang Ying Liu Haonan Zhu Wei Tan Guorui Zhu Yang Wang | 2018 | Transactions of Tianjin University2018，24，6： | 3 |
| 8 | Dynamic Load Identification in Time Domain显示文摘- In the time domain method the dynamic load is successfully identified when the accelerations, velocities and displacements or velocities and displacements of the structure are known. But in engineering practice or experiments usually only the acceleration response is recorded. In this paper an improved time domain method is proposed for dynamic load identification. In this method by using of Duhamel integral, only the acceleration response is required for load identification. As an application of the present method, the dynamic ice load on a Bohai offshore platform is identified based on some measured acceleration. The identified values of ice load are in good agreement with the measured ones. | Chu, Liangcheng Qu, Naisi Wu, Ruifeng Lu, Min Yang, Guojin | 1991 | China Ocean Engineering1991，6，3： | 3 |
| 9 | Faceted Kurdjumov-Sachs interface-induced slip continuity in the eutectic high-entropy alloy,AlCoCrFeNi_(2.1)显示文摘Recently,the eutectic high-entropy alloy(EHEA),AlCoCrFeNi_(2.1),can reach a good balance of strength and ductility.The dual-phase alloy exhibits a eutectic lamellar microstructure with large numbers of interfaces.However,the role of the interfaces in plastic deformation have not been revealed deeply.In the present work,the orientation relationship(OR)of the interfaces has been clarified as the Kurdjumov-Sachs(KS)interfaces presenting〈111〉_(B2) 〈110〉_(FCC)and {110} _(B2){111}_(FCC) independent of their morphologies.There exist three kinds of interfaces in the EHEA,namely,The dominating interface and the secondary interface are both non-slip planes and atomistic-scale faceted,facilitating the nucleation and slip transmission of the dislocations.The formation mechanism of the preferred interfaces is revealed using the atomistic geometrical analysis according to the criteria of the low interfacial energy based on the coincidence-site lattice(CSL)theory.In particular,the ductility of the dual-phase alloy originates from the KS interface-induced slip continuity across interfaces,which provides a high slip-transfer geometric factor.Moreover,the strengthening effect can be attributed to the interface resistance for the dislocation transmission due to the mismatches of the moduli and lattice parameters at the interfaces. | Ting Xiong Wenfan Yang Shijian Zheng Zhaorui Liu Yiping Lu Ruifeng Zhang Yangtao Zhou Xiaohong Shao Bo Zhang Jun Wang Fuxing Yin Peter K.Liaw Xiuliang Ma | 2021 | Journal of Materials Science & Technology2021，，6： | 2 |
| 10 | Salivary microbiota may predict the presence of esophageal squamous cell carcinoma显示文摘The aim is to explore the predictive value of salivary bacteria for the presence of esophageal squamous cell carcinoma (ESCC). Saliva samples were obtained from 178 patients with ESCC and 101 healthy controls, and allocated to screening and verification cohorts, respectively. In the screening phase, after saliva DNA was extracted, 16S rRNA V4 regions of salivary bacteria were amplified by polymerase chain reaction (PCR) with high-throughput sequencing. Highly expressed target bacteria were screened by Operational Taxonomic Units clustering, species annotation and microbial diversity assessment. In the verification phase, the expression levels of target bacteria identified in the screening phase were verified by absolute quantitative PCR (Q-PCR). Receiver operating characteristic (ROC) curves were plotted to investigate the predictive value of target salivary bacteria. LEfSe analysis revealed higher proportions of Fusobacterium, Streptococcus and Porphyromonas, and Q-PCR assay showed significantly higher numbers of Streptococcus salivarius, Fusobacterium nucleatum and Porphyromonas gingivalis in patients with ESCC, when compared with healthy controls (all P < 0.05). The areas under the ROC curves for Streptococcus salivarius, Fusobacterium nucleatum, Porphyromonas gingivalis and the combination of the three bacteria for predicting patients with ESCC were 69%, 56.5%, 61.8% and 76.4%, respectively. The sensitivities corresponding to cutoff value were 69.3%, 22.7%, 35.2% and 86.4%, respectively, and the matched specificity were 78.4%, 96.1%, 90.2% and 58.8%, respectively. These highly expressed Streptococcus salivarius, Fusobacterium nucleatum and Porphyromonas gingivalis in the saliva, alone or in combination, indicate their predictive value for ESCC. | Junmin Wei Ruifeng Li Yanxian Lu Fan Meng Bohong Xian Xiaorong Lai Xiayi Lin Yu Deng Dongyang Yang Huabin Zhang Liangfang Li Xiaosong Ben Guibin Qiao Wanwei Liu Zijun Li | 2022 | Genes & Diseases2022，9，4： | 2 |
| 11 | Association of single nucleotide polymorphisms of brain-derived neurotrophic factor gene and multidrug resistance 1 gene to refractory epilepsy in Chinese Han children显示文摘BACKGROUND:There are two hypotheses for the underlying cause of refractory epilepsy:'target'and'transport'.Studies have shown that brain-derived neurotrophic factor(BDNF) is over-expressed in refractory epilepsy.Multidrug resistance 1(MDR1) gene encodes for P-glycoprotein,the primary ATP-binding cassette transporter in the human body.Some single nucleotide polymorphisms of the MDR1 gene have been associated with refractory epilepsy. OBJECTIVE:To investigate the association between BDNF gene C270T polymorphism and MDR1 T-129C polymorphism with refractory epilepsy in Chinese Han children through the use of polymerase chain reaction(PCR)-restriction fragment length polymorphism analysis. DESIGN,TIME AND SETTING:A case-control,genetic association study was performed at the Central Laboratory,Third Xiangya Hospital of Central South University from June 2005 to November 2007. PARTICIPANTS:A total of 84 cases of unrelated children with epilepsy,including 41 cases of refractory epilepsy and 43 cases of drug-responsive epilepsy,were enrolled.An additional 30 healthy,Chinese Han children,whose ages and gender matched the refractory epilepsy patients, were selected as normal controls. METHODS:Venous blood was collected and genomic DNA was extracted from the blood specimens.C270T polymorphism in BDNF gene and T-129C polymorphism in MDR1 gene were genotyped using PCR-restriction fragment length polymorphism analysis.Association analysis using the Ftest and Chi-square test was statistically performed between C270T polymorphism in BDNF gene and T-129C polymorphism in MDR1 gene and refractory epilepsy. MAIN OUTCOME MEASURES:The distribution of genotypes and allele frequencies of C270T polymorphism in BDNF gene and T-129C polymorphism in MDR1 gene. RESULTS:The distribution of CC,CT,and TT genotypes,as well as C and T allele frequencies,in the BDNF gene was not significantly different between the refractory epilepsy group, drug-responsive epilepsy group,or the normal control group(P>0.05).The distribution of TT genotype and T allele frequencies of the MDR1 gene was significantly different in the refractory epilepsy group compared with the drug-responsive epilepsy and normal control groups(P<0.05). Comparison of haplotype combinations demonstrated that there were no significant differences in combinations of TT+CC,TT+CT,TC+CC,and TC+CT among the three groups(P>0.05). CONCLUSION:C270T polymorphism of the BDNF gene was not associated with refractory epilepsy in Chinese Han children,but T-129C polymorphism in the MDR1 gene was associated with refractory epilepsy in Chinese Han children.The TT genotype and T allele frequencies could serve as susceptibility loci for refractory epilepsy.Interactions between C270T in BDNF gene and T-129C in MDR1 gene were not observed in refractory epilepsy in Chinese Han children. | Guangxin Wang Zuocheng Yang Ruifeng Jin Ruopeng Sun | 2009 | Neural Regeneration Research2009，4，11： | 2 |
| 12 | 调强适形放疗在乳腺癌保乳术后应用的系统评价(英文)显示文摘Objective:The aim of this study was to assess the long-term effect of breast conservation with breast intensitymodulated radiotherapy (IMRT) for early-stage breast cancers.Methods:Pub Med,EMBASE,Cochrane Library,Chinese Biomedical Literature Database were searched to identify relevant original published trails,and the references of eligible studies were manually screened.Randomized controlled trails reported in any language,comparing breast IMRT with conventional radiotherapy (RT) in patients with early-stage breast cancer were eligible for inclusion.Two investigators independently assessed the quality of included trials and extracted data.The RevMan 5.0 software was used for statistical analysis.Results:Four trials involving 1440 patients were included.The results showed that in the IMRT group,the occurrence of acute moist dermatitis,the edema of the mammary gland and the occurrence of hyperpigmentation were lower than those of RT group,the pooled risk ratio value and 95% confidence interval were 0.28 (0.17-0.48),0.03 (0.00-0.21) and 0.06 (0.02-0.15) respectively.The use of IMRT did not correlate with pain and quality of life,but the presence of moist desquamation did significantly correlate with pain and reduced quality of life.Conclusion:The currently available evidence showed that IMRT significantly reduces the occurrence of moist acute dermatitis anywhere in the breast and alleviates the suffering of patients and improves the quality of life of patients.Future large-scale,high-quality,double-blind trials are needed. | Xiupeng Ye Ling Su Xiaohu Wang Kehu Yang inhui Tian Qiuning Zhang Qiang Wang Xiaojun Li Yuqing Kang Liyun Guo Ruifeng Liu Shifang Feng | 2010 | The Chinese-German Journal of Clinical Oncology2010，9，12： | 2 |
| 13 | Two novel cis-elements involved in hepatocyte nuclear factor 4α regulation of acyl-coenzyme A:cholesterol acyltransferase 2 expression显示文摘酰辅酶 A:cholesterol acyltransferase (ACAT2 ) 2 为胆固醇酉旨合成和分泌物是重要的。以前的研究表明那项 ACAT2 基因倡导者活动是由 hepatocyte 的 upregulated 原子因素 4 (HNF4 ) 通过在 247 ACAT2 和 311 基因倡导者附近的二个地点。这里,我们识别了二新奇 cis 元素,地点我(1006 ~ 898 ) 并且地点 II (38 ~ 29 ) ,它为 HNF4 是重要的效果。在 HepG2 房间,地点的变化我减少了 ACAT2 基因倡导者活动到野类型的中的五分之一个个,当地点 II 的变化把倡导者活动归结为野类型的不到十分之一时。在 293T 房间,这二 cis 元素的变化深刻地损害了 HNF4 正式就职效果。当这二个元素的任何一个被插入到 pGL3 倡导者时, HNF4 通过插入的元素导致了倡导者活动,当元素的变化损害了 HNF4 正式就职效果时。在 electrophoretic 活动性移动试金和染色质 immunoprecipitation 实验, HNF4 跳了到这二个元素。因此,二 cis 元素为 ACAT2 基因抄写上的 HNF4 效果是重要的。我们也证明 HNF4 断然在 mRNA 水平调整 ACAT2 基因表示。HNF4 的 Overexpression 增加了 ACAT2 表示,而 HNF4 击倒减少的 ACAT2 表示。Peroxisome 激活 proliferator 的受体 gamma 激活剂 1 (PCG1 ) , HNF4 的激活剂,,增加了 ACAT2 表示小 heterodimer 搭挡(SHP ) , HNF4 的 corepressor,减少的 ACAT2 表示。这些结果提供更多的卓见进 ACAT2 表示的 transcriptional 规定。 | Zhuqin Zhang Jinjing Liu Yang Xi Ruifeng Yang Houzao Chen Zhenya Li Depei Liu Chihchuan Liang | 2012 | Acta Biochimica et Biophysica Sinica2012，44，2： | 1 |
| 14 | Anti-viral memory T cell responses in the absence of IgG production in a COVID-19 convalescent individual显示文摘Cellular and humoral immunity are both important in host defense against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Although defects in SARS-CoV-2-specific T cell immunity have been found in patients with severe lung pathology,it is still largely unclear whether virus-specific T cells are sufficient for host protection.Here,we found that in a previously characterized cohort of convalescent subjects,one individual,though lacking detectable anti-viral neutralizing IgG antibodies,showed virus-specific T cell responses,both in CD4^(+)and CD8^(+)T cells.SARS-CoV-2-specific T cells in this and other individuals are maintained for up to 10 months.This study thus further supports a critical role of T cells in host defense against SARS-CoV-2,offering new insights into the design and evaluation of COVID-19 vaccines. | Ling Ni Fang Ye Qin Qiao Yu Feng Yazheng Yang Hui Zhao Li-Nan Zhang Meng-Li Cheng Gengzhen Zhu Xiaoli Li Xuan Zhong Ruifeng Li Cheng-Feng Qin Fang Chen Chen Dong | 2022 | National Science Open2022，1，1： | 1 |
| 15 | Hot-corrosion behavior associated with the evolution of corrosion scales of a Ni-based superalloy in molten salts显示文摘The degradation of Ni-based superalloys in molten salts is closely related with the evolution of corrosion scales.In this work,the evolution of corrosion scales,the characteristics of the scale/alloy matrix interface associated with the corrosion mechanisms and the corrosion kinetics of a Ni-based superalloy Ni–20 Cr–18 W in molten salts were investigated.The outer surface of the corrosion scales was composed of numerous flakes.From the cross-sectional view,the scales gradually presented a layered structure and its formation can be ascribed to the morphology evolution of the inclusions inserted within the scales.It was found that the corrosion progress was a cooperative process involving in both oxidation and sulfuration,and the element of sulfur(S)took the precedence to penetrate into the matrix and resulted in an obvious sulfuration zone nearby the scales/alloy matrix interface.The corrosion activation energy of the investigated alloy was calculated to be 125.27 k J/mol.This work is expected to work out the structural evolution of the corrosion scales and the characteristics of the scale/matrix interface associated with the corrosion mechanisms for Ni-based superalloys. | Ruifeng Dong Dong Liu Tiebang Zhang Ling Yang Li Wu Yuhong Zhao Hua Hou | 2021 | Progress in Natural Science:Materials International2021，31，3： | 1 |
| 16 | Long noncoding RNA PVT1 promotes tumor growth and predicts poor prognosis in patients with diffuse large B-cell lymphoma显示文摘Dear Editor,Diffuse large B-cell lymphoma(DLBCL)is the most common and aggressive subtype of non-Hodgkin lymphoma(NHL),accounting for about 40%of all NHL cases[1].Lacking symptoms at early time and efficient therapeutic methods made DLBCL one of the most life-threatening types of hematopoietic malignancy[2,3].Therefore,identifying novel therapeutic biomarker for early detection and prognosis prediction is urgently needed. | Ruifeng Yang Tingting Shao Manmei Long Yongheng Shi Qiang Liu Linhua Yang Ming Zhan | 2020 | Cancer Communications2020，40，10： | 1 |
| 17 | Effect of GR24 Stereoisomers on Plant Development in Arabidopsis显示文摘 | Suhua Li Linhai Chen Yuwen Li Ruifeng Yao Fei Wang Mai Yang Min Gu Fajun Nan Daoxin Xie Jianbin Yan | 2016 | Molecular Plant2016，9，10： | 1 |
| 18 | Rock Types and Reservoir Characteristics of Shahejie Formation Marl in Shulu Sag, Jizhong Depression, Bohai Bay Basin显示文摘Due to the complicated lithology in the ES3 Member of the Shahejie Formation in the Shulu sag,Jizhong depression,it is difficult to classify the rock types and characterize the reservoirs at the marl intervals.In this paper,a four-element classification method has been proposed,and seven rock types have been identified by analyzing the mineral composition.The primary rock types are medium-high organic carbonate rocks and medium-high organic shaly-siliceous carbonate rocks.With the methods of field emission scanning electron microscopy,high-pressure mercury intrusion,nitrogen adsorption,and nano-CT,four types of reservoir spaces have been identified,including intra-granular pores,intergranular pores(inter-crystalline pores),organic pores,and micro-fractures.By combining the method of high-pressure mercury intrusion with the method of the nitrogen adsorption,the porosity of the marl has been measured,ranging from 0.73%to 5.39%.The distribution of the pore sizes is bimodal,and the pore types are dominated by micron pores.Through this study,it has been concluded that the sag area to the east of Well ST1H is the favorable area for the development of self-sourced and self-reservoired shale oil.According to the results of geochemical and reservoir analysis,the III Oil Group may have sweet spot layers. | Jingwei Cui Xuanjun Yuan Songtao Wu Ruifeng Zhang Song Jin Yang Li | 2021 | Journal of Earth Science2021，32，4： | 1 |
| 19 | High-resolution genetic mapping at the Bph15 locus for brown planthopper resistance in rice (Oryza sativa L.)显示文摘 | Haiyuan Yang Aiqing You Zhifan Yang Futie Zhang Ruifeng He Lili Zhu Guangcun He | 2004 | Theoretical and Applied Genetics2004，，1： | 1 |
| 20 | Gradient-based iterative parameter estimation for Box–Jenkins systems显示文摘 | Dongqing Wang Guowei Yang Ruifeng Ding | 2010 | Computers and Mathematics with Applications2010，，5： | 1 |
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