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| 1 | Ultra Dense Network:Challenges,Enabling Technologies and New Trends显示文摘5G sets an ambitious goal of increasing the capacity per area of current 4G network by 1000 fold. Due to the high splitting gain of dense small cells, ultra dense network(UDN) is widely considered as a key component in achieving this goal. In this paper, we outline the main challenges that come with dense cell deployment, including interference, mobility, power consumption and backhaul. Technologies designed to tackle these challenges in long term evolution system(LTE) and their deficiencies in UDN context are also analyzed. To combat these challenges more efficiently, a series of technologies are introduced along with some of our initial research results. Moreover, the trends of user-centric and peer-to-peer design in UDN are also elaborated. | HAO Peng YAN Xiao Yu-Ngok Ruyue YUAN Yifei | 2016 | China Communications2016，13，2： | 21 |
| 2 | Vision,application scenarios,and key technology trends for 6G mobile communications显示文摘With the global commercialization of the fifth-generation(5G)network,many countries,including China,USA,European countries,Japan,and Korea,have started exploring 6G mobile communication network,following the tradition of“planning the next while commercializing one generation”.Currently,studies on 6G networks are at the infancy stage.Research on the vision and requirements for 6G is still ongoing,and the industry is yet to clarify the key enabling technologies for 6G.However,6G will certainly build on the success of 5G.Therefore,developing high-quality 5G networks and seamlessly integrating 5G with verticals are the priorities before 2030,when 6G is projected to be commercialized.Also,global 5G standards will keep evolving to better support vertical applications.As a milestone,the Third-Generation Partnership Project(3GPP)published Release 16 in July 2020,which continuously enhanced the capabilities of mobile broadband service based on Release 15 and realized the support for low-delay and high-reliability applications,such as Internet of Vehicles and industrial Internet.Currently,3GPP is working on Releases 17 and 18,focusing on meeting the demands of medium-and high-data-rate machine communication with low-cost and high-precision positioning,which will be published in June 2022.Thus,6G networks will further expand the application fields and scope of the Internet of Things to accommodate those services and applications that are beyond the capabilities of 5G networks.Herein,we present our vision,application scenarios,and key technological trends for 6G networks.Furthermore,we propose several future research opportunities in 6G networks with regard to industrialization and standardization. | Zhiqin WANG Ying DU Kejun WEI Kaifeng HAN Xiaoyan XU Guiming WEI Wen TONG Peiying ZHU Jianglei MA Jun WANG Guangjian WANG Xueqiang YAN Jiying XIANG He HUANG Ruyue LI Xinhui WANG Yingmin WANG Shaohui SUN Shiqiang SUO Qiubin GAO Xin SU | 2022 | Science China(Information Sciences)2022，65，5： | 17 |
| 3 | Western medication plus Traditional Chinese Medicine preparations in patients with chronic heart failure:a prospective,single-blind,randomized,controlled,and multicenter clinical trial显示文摘OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, controlled, and multicenter clinical trial began on September 17, 2008, and was completed on June 25, 2011. A total of 340 inpatients, aged 40-79 years, with exacerbating CHF from 10 hospitals were enrolled and randomly allocated within 24 h of admission. The trial included three intervention periods. During hospitalization, the control group received western medication for CHF and the treatment group received Danhong injection with Shenfu injection or Shenmai injection. After discharge,all patients were treated with Qiliqiangxin capsules and Buyiqiangxin tablets or a placebo for 6 months. After the 6-month intervention, both groups received only continuous western medication. The primary endpoint was all-cause mortality.The efficacy assessments were as follows: B-type natriuretic peptide(BNP), Lee's HF score, the 6-minute walking test(6 MWT), left ventricular ejection fraction(LVEF), and the Minnesota Living with Heart Failure Questionnaire(MLHFQ). The safety assessments were as follows: blood and urine routine examination, hepatic and renal function, electrolytes in blood and adverse events.RESULTS: Compared with the control group, the treatment group showed a 30.99% reduction in all-cause mortality and an improved survival rate.The treatment group showed greater improvement in 6 MWT(P = 0.02) than the control group on discharge, after 12-month follow-up, there was a time-group interaction for MLHFQ(P = 0.03). Incidence rate of adverse events and other relevant safety indexes were not statistically significant between the two groups.CONCLUSION: Western medication plus TCM treatment can increase 6-minute walking distance(improve exercise tolerance) and quality of life with heart failure patients. | Wang Xianliang Hou Yazhu Mao Jingyuan Zhao Yingqiang Niu Tianfu Yuan Ruyu Wang Yonggang Cui Jin-rong Shi Le Jia Xiuli Fan Ruihong Lin Qian Zhang Yan Li Zhijun Shang Hongcai Wang Baohe Wang Hongwu Wang Henghe Cui Xiaolei Soh Shanbin Ruan Jishou Zhang Boli | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 15 |
| 4 | Differential Characteristics of the Upper Ordovician-Lower Silurian Wufeng-Longmaxi Shale Reservoir and its Implications for Exploration and Development of Shale Gas in/around the Sichuan Basin显示文摘The Upper Ordovician Wufeng-Lower Silurian Longmaxi shale is widely distributed in the Sichuan Basin and its periphery,which is the key stratum for marine shale gas exploration and development(E&D)in China.Based on sedimentary environment,material basis,storage space,fracability and reservoir evolution data,the reservoir characteristics of the Wufeng-Longmaxi shale and their significance for shale gas E&D are systematically compared and analyzed in this paper.The results show that(1)the depocenter of the Wufeng(WF)-Longmaxi(LM)shale gradually migrates from east to west.The high-quality shale reservoirs in the eastern Sichuan Basin are mainly siliceous shales,which are primarily distributed in the graptolite shale interval of WF2-LM5.The high-quality reservoirs in the southern Sichuan Basin are mainly calcareous-siliceous and organic-rich argillaceous shales,which are distributed in the graptolite shale interval of WF2-LM7.(2)Deep shale gas(the burial depth>3500 m)in the Sichuan Basin has high-ultrahigh pressure and superior physical properties.The organic-rich siliceous,calcareous-siliceous and organic-rich argillaceous shales have suitable reservoir properties.The marginal area of the Sichuan Basin has a higher degree of pressure relief,which leads to the argillaceous and silty shales evolving into direct cap rocks with poor reservoir/good sealing capacity.(3)Combining shale gas exploration practices and impacts of lithofacies,depth,pressure coefficient and brittle-ductile transition on the reservoir properties,it is concluded that the favorable depth interval of the Wufeng-Longmaxi shale gas is 2200~4000 m under current technical conditions.(4)Aiming at the differential reservoir properties of the Wufeng-Longmaxi shale in the Sichuan Basin and its periphery,several suggestions for future research directions and E&D of shale gas are formulated. | WANG Ruyue HU Zongquan LONG Shengxiang LIU Guangxiang ZHAO Jianhua DONG Li DU Wei WANG Pengwei YIN Shuai | 2019 | Acta Geologica Sinica(English Edition)2019，93，3： | 8 |
| 5 | Inositol Pyrophosphate lnsP8 Acts as an Intracellular Phosphate Signal in Arabidopsis显示文摘The maintenance of cellular phosphate(Pi)homeostasis is of great importance in living organisms.The SPX domain-containing protein 1(SPX1)proteins from both Arabidopsis and rice have been proposed to act as sensors of Pi status.The molecular signal indicating the cellular Pi status and regulating Pi homeostasis in plants,however,remains to be identified,as Pi itself does not bind to the SPX domain.Here,we report the identification of the inositol pyrophosphate lnsP8 as a signaling molecule that regulates Pi homeostasis in Arabidopsis.Polyacrylamide gel electrophoresis profiling of InsPs revealed that lnsP8 level positively correlates with cellular Pi concentration.We demonstrated that the homologs of diphosphoinositol pentaki-sphosphate kinase(PPIP5K),VIH1 and VIH2,function redundantly to synthesize lnsP8,and that the vih1 vih2 double mutant overaccumulates Pi.SPX1 directly interacts with PHR1,the central regulator of Pi starvation responses,to inhibit its function under Pi-replete conditions.However,this interaction is compromised in the vih1 vih2 double mutant,resulting in the constitutive induction of Pi starvation-induced genes,indicating that plant cells cannot sense cellular Pi status without lnsP8.Furthermore,we showed that lnsP8 could directly bind to the SPX domain of SPX1 and is essential for the interaction between SPX1 and PHR1.Collectively,our study suggests that lnsP8 is the intracellular Pi signaling molecule serving as the ligand of SPX1 for controlling Pi homeostasis in plants. | Jinsong Dong Guojie Ma Liqian Sui Mengwei Wei Viswanathan Satheesh Ruyue Zhang Shenghong Ge Jinkai Li Tong-En Zhang Christopher Wittwer Henning JJessen Huiming Zhang Guo-Yong An Dai-Yin Chao Dong Liu Mingguang Lei | 2019 | Molecular Plant2019，12，11： | 8 |
| 6 | Reconstruction of nerve root sheaths for sacral extradural spinal meningeal cysts with spinal nerve root fibers显示文摘This study analyzed the clinical characteristics and outcomes of sacral extradural spinal meningeal cysts with spinal nerve root fibers treated by reconstruction of the nerve root sheaths.The relationships between the cysts and spinal nerve root fibers were examined microscopically,the cysts were partially excised,and the defects were oversewn to reconstruct the nerve root sheaths.The Improved Japanese Orthopedic Association(IJOA)scoring system was used to evaluate preoperative and postoperative neurological function.Thirty-eight patients were included in this study,with a mean age of 41.4±15.57 years.The mean IJOA score was 18.8±1.32 preoperatively and 19.6±0.65 postoperatively,which was a significant difference(t=–3.77,P=0.001).These results indicate a significant improvement in neurological function after surgery.The most significant improvement in neurological function was sensation(z=–2.86,P=0.004),followed by bowel/bladder function(z=–2.31,P=0.02). | SUN JianJun WANG ZhenYu LI ZhenDong WU HaiBo YEN RuYu ZHENG Mei CHANG Qing LIU Isabelle Yisha | 2013 | Science China(Life Sciences)2013，56，11： | 8 |
| 7 | Kallistatin,a new and reliable biomarker for the diagnosis of liver cirrhosis显示文摘Kallistatin,which protects organs and cells against inflammation,fibrosis and oxidative stress,is mainly synthesized and secreted in liver.However,its relationship to human liver disease remains unclear.The purpose of this study was to explore the relationship between serum kallistatin and clinical evidence of both cirrhosis and hepatocellular carcinoma(HCC),and to determine if serum kallistatin levels could be used as a diagnostic indicator of hepatic health status,especially human liver cirrhosis(LC).Our cohort consisted of 115 patients with clinically proven liver fibrosis(LF),LC,or HCC by liver biopsies,and 31 healthy controls(CON).Serum kallistatin levels were quantified by ELISA.Results of the present study demonstrated that irrespective of the underlying etiology,serum kallistatin levels were significantly lower in the LF/LC group when compared with the CON group.A decrease in serum kallistatin levels appeared to reflect the extent of cirrhosis,with the lowest levels associated with higher grades of cirrhosis.Patients with LC had a noticeable correlation between serum kallistatin levels and other serum biochemical indicators.The area under the curve(AUC) for LC,viral liver cirrhosis(VLC)and alcoholic liver cirrhosis(ALC) was 0.845,0.757 and 0.931,respectively.In conclusion,our findingsdemonstrated that kallistatin,a plasma protein produced by the liver,can be a useful and reliable diagnostic indicator of hepatic health status,especially for LC. | Zhiyun Cheng Yinghui Lv Suqiu Pang Ruyu Bai Mingxi Wang Shuyu Lin Tianwen Xu Duncan Spalding Nagy Habib Ruian Xu | 2015 | Acta Pharmaceutica Sinica B2015，5，3： | 7 |
| 8 | NiPS_(3)quantum sheets modified nitrogen-doped mesoporous carbon with boosted bifunctional oxygen electrocatalytic performance显示文摘Electrocatalysts for oxygen reduction reactions(ORR)and oxygen evolution reactions(OER)are highly crucial and challenging toward the energy storage and conversion technologies such as fuel cells,metal-air batteries and water electrolysis.To replace noble-metal based catalysts and boost catalytic performance of carbon-based materials,we initially develop the nickel,phospho rus,sulfur and nitrogen co-modified mesoporous carbon(NiPS_(3)@NMC)as a bifunctional oxygen electrocatalyst.The perfo rmance for ORR(half-wave potential at 0.90 V)and OER(10 mA cm^(-2)at 1.48 V)surpasses those of Pt/C coupled with IrO_(2)catalysts and most of the non-precious metal based bifunctional electrocatalysts reported in related literature.Moreover,the electrochemical durability is also confirmed by accelerated durability tests(ADTs)and long-term chronoamperometry(CA)tests.We demonstrated that the interfacial effect between NiPS_(3)quantum sheets(QS s)and NMC substrates by thermal activation contributed to the enhanced oxygen electrode bifunctionality with more active sites,due to the electrons-donating from nickel,phosphorus and sulfur elements and relatively enriched pyridinic type N.Such excellent overall performance highlights the potential application of NiPS3 QSs and NMC composites as the materials on energy conversion and storage. | Kai Huang Yuyang Xu Yanpeng Song Ruyue Wanga Hehe Wei Yuanzheng Long Ming Lei Haolin Tang Jiangang Guo Hui Wu | 2021 | Journal of Materials Science & Technology2021，，6： | 7 |
| 9 | NUMERICAL STUDIES ON RESONANT AND ENHANCEMENT EFFECTS FOR COUPLING OF MICROWAVE PULSES INTO NARROW SLOTS显示文摘In this paper, modifications to the finite-difference time-domain(FD-TD) method for modeling microwave pulse coupling into a slot, which is much narrower than one conventional FD-TD cell, are discussed. The coupling process of microwave pulse into a slot is studied by using the modified FD-TD method, and the dependence of microwave coupling on slot sizes, the carrier frequencies and the polarization directions of the incident waves is analysed. Resonant and enhancement effects which occur in this process are observed. The condition at which the resonant effect takes place is also presented. | Wang Jianguo Yu Hanqing Liu Guozhi Chen Yusheng Fan Ruyu (Northwest Institute of Nuclear Technology, Branch 15, P. O. Box 69, Xi’an 710024)Ge Debiao(Department of Physics, Xidian University, Xi’an 710071) | 1998 | Journal of Electronics(China)1998，15，2： | 6 |
| 10 | Numerical investigation on the assessment and mitigation of coal bump in an island longwall panel显示文摘This study presents a numerical investigation to assess the risk of coal bumps and produces a stress–relief technology using boreholes to mitigate risk during the extraction of an island longwall panel.Based on the geological condition in an island longwall panel in the Tangshan Coal Mine,Tangshan,China,a numerical FLAC3D(Fast Lagrangian Analysis of Continua in 3 Dimensions) model was established to determine and to map the zones in the panel with a high risk for coal bumps.The results of the numerical modeling show that the roof deformation starts to occur at more than 30 m ahead of the longwall face and the deformation starts to accelerate after a distance of 10 m in front of the longwall face.Large and rapid roof deformation is considered to be an important precursor of coal bump occurrence during the extraction of an island longwall panel.Based on the numerical results,a stress–relief technology using boreholes,which was employed to release abutment pressure,was investigated through numerical methods.The modeled results suggest that the peak stress concentration could be released by drilling boreholes in the zones prone to coal bumps.The effectiveness of the stress release increased with the borehole length and decreased with the borehole spacing. | Wang Hongwei Jiang Yaodong Zhu Jie Shan Ruyue Wang Chen | 2013 | International Journal of Mining Science and Technology2013，23，5： | 6 |
| 11 | Conditional QTL mapping of three yield components in common wheat(Triticum aestivum L.)显示文摘Spike number per m^2(SN),kernel number per spike(KNPS) and thousand-kernel weight(TKW)are the three main components determining wheat(Triticum aestivum L.) yield.To evaluate the relationships among them a doubled haploid(DH) population consisting of 168 lines grown at three locations for three years was analyzed by unconditional and conditional QTL mapping.Thirty-three unconditional QTL and fifty-nine conditional QTL were detected.Among them,two QTL(QSN-DH-2B and QSN-DH-3A-1.1) improved SN,with no effect on KNPS.QKNPS-DH-2B-2.1 improved KNPS,with no effect on SN.QKNPS-DH-1A-1.1,QKNPS-DH-2D-1.1and QKNPS-DH-6A improved KNPS,with no effect on SN or TKW.QKNPS-DH-6B was associated with increased SN and TKW.In addition,QTKW-DH-4B,QTKW-DH-5B and QTKW-DH-7B increased TKW without decreasing KNPS.These results provide useful information for marker assisted selection(MAS) and improvement in wheat yield. | Han Zhang Jiansheng Chen Ruyu Li Zhiying Deng Kunpu Zhang Bin Liu Jichun Tian | 2016 | The Crop Journal2016，4，3： | 5 |
| 12 | Reductive Amination of Carbonyl Compounds with Ammonia and Hydrogenation of Nitriles to Primary Amines with Heterogeneous Cobalt Catalysts显示文摘Reductive amination of aldehydes/ketones with aqueous NH3 and hydrogenation of nitriles to primary amines with Co catalysts were reported. Co@NC-700 exhibited remarkable activity and high selectivity for the reductive amination of aldehydes/ketones with aqueous NH3 and the hydrogenation of nitriles to primary amines. Several primary amines can be obtained with good to excellent yields via the reductive amination of aldehydes/ketones and the hydrogenation of nitriles. The nitrogen-doped carbon(C)-supported Co@NC-700 metal catalyst was prepared via the pyrolysis of bioMOF Co/adenine in activated C. Co@NC-700 can be reused five times without evident loss of activity. | LIU Junmei GUO Wanwan SUN Hao LI Ruyue FENG Zhipeng ZHOU Xuyang HUANG Jun | 2019 | Chemical Research in Chinese Universities2019，35，3： | 2 |
| 13 | Bioactive skin-mimicking hydrogel band-aids for diabetic wound healing and infectious skin incision treatment显示文摘The treatment of diabetic chronic wounds remains a global challenge due to the up-regulated inflammation response,oxidant stress,and persistent infection during healing process.Developing wound dressing materials with ideal biocompatibility,adequate mechanical strength,considerable under-water adhesion,sufficient anti-inflammation,antioxidant,and antibacterial properties is on-demand for clinical applications.In this study,we developed a bioactive skin-mimicking hydrogel band-aid through the combination of tannic acid(TA)and imidazolidinyl urea reinforced polyurethane(PMI)(TAP hydrogel)and explored its potentials in various medical applications,including hemostasis,normal skin incision,full-thickness skin wounds,and bacterial-infection skin incision on diabetic mice.TA was loaded into PMI hydrogel network to enhance the mechanical properties of TAP hydrogels through multiple non-covalent interactions(break strength:0.28-0.64 MPa;elongation at break:650-930%),which could resist the local stress and maintain the structural integrity of wound dressings during applications.Moreover,owing to the promising moisture-resistant adhesiveness and organ hemostasis,outstanding anti-inflammation,antibacterial,and antioxidant properties,TAP hydrogels could efficiently promote the recovery of skin incision and defects on diabetic mice.To further simulate the practical situation and explore the potential in clinical application,we also verified the treatment efficiency of TAP hydrogel in S.aureus-infected skin incision model on diabetic mice. | Yuxuan Yang Xiaodan Zhao Jing Yu Xingxing Chen Ruyue Wang Mengyuan Zhang Qiang Zhang Yanfeng Zhang Shuang Wang Yilong Cheng | 2021 | Bioactive Materials2021，6，11： | 2 |
| 14 | Properties and photodetector applications of two-dimensional black arsenic phosphorus and black phosphorus显示文摘Two-dimensional(2D)black arsenic phosphorus(b-AsP),as an alloy of black phosphorus(bP)with arsenic,has attracted great attention because of its outstanding electronic and optical properties,including high carrier mobility,tunable bandgap and in-plane anisotropy.B-AsP has a smaller bandgap(0.15–0.3 eV)than the b-P bandgap(0.3–2.0 eV),and thus can be used for mid-infrared photodetectors.In addition,both of them can form various van der Waals(vdW)heterojunctions with other 2D materials to realize novel functional optoelectronic devices.Here,we compare the basic characteristics of b-AsP and b-P,including crystal structure,optical properties,band structure,electrical properties and stability,and we summarize the update progress of b-AsP in photo detection,including representatives of phototransistor and photodiode devices.In the last part,the future research directions are discussed. | Ruyue HAN Shun FENG Dong-Ming SUN Hui-Ming CHENG | 2021 | Science China(Information Sciences)2021，64，4： | 2 |
| 15 | A hybrid FDTD-SPICE method for transmission lines excited by a nonuniform incident wave 显示文摘 | Xie Haiyan Wang Jianguo Fan Ruyu | 2009 | IEEE Trans on Electromagn Comlpat2009，51，3： | 1 |
| 16 | MicroRNAs‐372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B显示文摘 | Hongyan Guo Haiying Liu Keith Mitchelson Huiying Rao Mingyong Luo Lan Xie Yimin Sun Liang Zhang Ying Lu Ruyu Liu Aihui Ren Shuai Liu Shaozhen Zhou Jiye Zhu Yuxiang Zhou Ailong Huang Lai Wei Yong Guo Jing Cheng | 2011 | Hepatology2011，，3： | 1 |
| 17 | RSAT^IM Process Development for Post-Combustion C02 Capture:Scale-up from Laboratory and Pilot Test Data to Commercial Process Design显示文摘 | ZHANG Ruyu BONNIN-NARTKER E P FARTHING G A | 2011 | Energy Procedia2011，4，： | 1 |
| 18 | Numerical studies on nonlinear coupling of high-power microwave pulses into a cylindrical cavity显示文摘 | Wang Jianguo Chen Yusheng Fan Ruyu | 1996 | IEEE Trans Plasma Science1996，24，1： | 1 |
| 19 | Optimal stochastic design four-bar mechanism for tolerance and clearance显示文摘 | Je Ha Ruyu Byung Man Kwak | 1988 | Transactions of ASME1988，110，9： | 1 |
| 20 | A hybrid FDTD-SPICE method for transmission lines excited by a nonuniform incident wave显示文摘 | Xie Haiyan Wang Jianguo Fan Ruyu | 2009 | IEEE Trans on Electromag Compat2009，51，3： | 1 |
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