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| 1 | Phenolic ripeness assessment of grape skin by texture analysis 显示文摘 | Susana R S Luca R Vincenzo G | 2008 | Journal of Food Composition and Analysis2008，21，8： | 1 |
| 2 | Modeling respiration rate of fresh fruits and vegetable for modified atmosphere packages: a review显示文摘 | Susana C F Fernanda A R Jeffrey K B | 2002 | Journal of Food Engineering2002，52，6： | 1 |
| 3 | Industrial and biotechnological applications of laccases:a review显示文摘 | SUSANA R C JOSé LUIS T H | 2006 | Biotechnology Advances2006，24，： | 1 |
| 4 | Pediatric primary diffuse large cell lymphoma of bone with t (3;22)(q27; q11)显示文摘 | Federico A Frederick B Susana R | 1998 | J Pedia Hemotol1998，20，： | 1 |
| 5 | Phenolic ripeness assessment of grape skin by texture analysis 显示文摘 | SUSANA R S LUCA R VINCENZO G | 2008 | Journal of Food Composition and Analysis2008，21，8： | 1 |
| 6 | Modeling res- piration rate of shredded Galena kale for development of modi- fied atmosphere packaging 显示文摘 | Susana C F Fernanda A R O Jesus M F | 2002 | Journal of Food Engineering2002，54，4： | 1 |
| 7 | Multiplexed Biosensing Diagnostic Platforms Detecting Autoantibodies to Tumor-Associated Antigens from Exosomes Released by CRC Cells and Tissue Samples Showed High Diagnostic Ability for Colorectal Cancer显示文摘Colorectal cancer(CRC)is the second leading cause of cancer-related death worldwide.The five-year survival rate of CRC patients depends on the stage at diagnosis,being higher than 80%when CRC is diagnosed in the early stages but lower than 10%when CRC is diagnosed in advanced stages.Autoantibodies against specific CRC autoantigens(tumor-associated antigens(TAAs))in the sera of patients have been widely demonstrated to aid in early diagnosis.Thus,we herein aim to identify autoantigens target of autoantibodies specific to CRC that possess a significant ability to discriminate between CRC patients and healthy individuals by means of liquid biopsy.To that end,we examined the protein content of the exosomes released by five CRC cell lines and tissue samples from CRC patients by means of immunoprecipitation coupled with mass spectrometry analysis.A total of 103 proteins were identified as potential autoantigens specific to CRC.After bioinformatics and meta-analysis,we selected 15 proteins that are more likely to be actual CRC autoantigens in order to evaluate their role in CRC prognosis by Western blot(WB)and immunohistochemistry(IHC).We found dysregulation at the protein level for 11 of these proteins in both tissue and plasma exosome samples from patients,along with an association of nine of these proteins with CRC prognosis.After validation,all but one showed a statistically significant high diagnostic ability to distinguish CRC patients and individuals with premalignant lesions from healthy individuals,either by luminescence Halotag-based beads,or by a multiplexed biosensing platform involving the use of magnetic microcarriers as solid support modified with covalently immobilized Halotag fusion proteins constructed for CRC detection.Taken together,our results highlight the usefulness of the approach defined here to identify the TAAs specific to chronic diseases;they also demonstrate that the measurement of autoantibody levels in plasma against the TAAs identified here could be integrated into a point-of-care(POC)device for CRC detection with high diagnostic ability. | Ana Montero-Calle Itziar Aranguren-Abeigon María Garranzo-Asensio Carmen Poves María Jesús Fernández-Aceñero Javier Martínez-Useros Rodrigo Sanz Jana Dziaková Javier Rodriguez-Cobos Guillermo Solís-Fernández Eloy Povedano Maria Gamella Rebeca Magnolia Torrente-Rodríguez Miren Alonso-Navarro Vivian de los Ríos J.Ignacio Casal Gemma Domínguez Ana Guzman-Aranguez Alberto Peláez-García JoséManuel Pingarrón Susana Campuzano Rodrigo Barderas | 2021 | Engineering2021，7，10： | 1 |
| 8 | Mitochondrial localization of a NADR - dependent isocitratedehydrogenase isoenzyme by using the green fluorescent protein as a marker显示文摘 | Susana G Odile R Evelyne B | 1998 | Plant biology1998，，95： | 1 |
| 9 | Effects of virtual reality upper limb based training (rehabilitation gaming system) on spasticity, shoulder pain, and depression after stroke 显示文摘 | Susana R Sergi BB Ampar CF | 2011 | PM&R2011，3，101： | 1 |
| 10 | RAPD-PCR analysis of Staphylococcus aureus strains isolated from bovine and human hosts显示文摘 | Elina R Susana B Cecilia F | 2004 | Microbiological Research2004，159，： | 1 |
| 11 | A comparative study of revese osmosis and freeze concentration for the removal of valerie acid from wastewaters显示文摘 | MARINO RODRIGUEZ SUSANA LUQUE JOSE R ALVAREZ JOSE COCA | 2000 | Desalination2000，，127： | 1 |
| 12 | Composition and Antimicrobial Activity of the Essential Oils from Invasive Species of the Azores,Hedychium gardnerianum and Pittosporum undulatum显示文摘 | Jorge R M Lurdes B C Susana C M | 2003 | Phytochemistry2003，64，： | 1 |
| 13 | Influence of partial replacement of NaC1 with KCI, CaCI2 and MgCI2 on lipolysis and lipid oxidation in dry-cured ham显示文摘 | SUSANA R PAULO C B C MONICA A | 2011 | Meat Science2011，89，1： | 1 |
| 14 | Cardiomyocyte epoptic cell death in arterial hypertension mechanisms and potential management显示文摘 | Maria AF Susana R | 2001 | Hypertension2001，38，： | 1 |
| 15 | Berry skin thickness as main texture parameter to predict anthocyanin extractability in winegrapes显示文摘 | Susana Río Segade Simone Giacosa Vincenzo Gerbi Luca Rolle | 2010 | LWT - Food Science and Technology2010，，2： | 1 |
| 16 | Micropropagation of photinia employing rhizobacteria to promote mot development 显示文摘 | EZEQUIEI E L SUSANA M C ENRIQUE A R C | 2007 | Plant Cell Rep2007，26，： | 1 |
| 17 | Stimulating the use of biofuels in the European Union:Implications for climate change policy显示文摘 | Lisa R Frank C Susana F | 2006 | Energy Policy2006，34，17： | 1 |
| 18 | Spatiotemporal patterning of reactive oxygen production and Ca^2+ wave propagation in Fucus Rhizoid cells 显示文摘 | Susana M C Alison R T Keith P R | 2002 | Plant Cell2002，14，： | 1 |
| 19 | Annexin A5 downregulates surface expression of tissue factor显示文摘 | Susana R Abdelkader B Heidi K | 2005 | J Biol Chem2005，280，7： | 1 |
| 20 | CITRX thiore- doxin interacts with the tomato Cf- 9 resistance protein and negatively regulates defence 显示文摘 | Susana R Alejandra R C Matthew S | 2004 | The EMBO Journal2004，23，10： | 1 |
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