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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | Rice monitoring and production estimation using multitemporal RADARSAT显示文摘 | Yun Shao Xiangtao Fan Hao Liu Jianhua Xiao S Ross B Brisco R Brown G Staples | 2001 | Remote Sensing of Environment2001，，3： | 3 |
| 3 | Associations between particle physicochemical characteristics and oxidative capacity: An indoor PM 10 study in Beijing, China显示文摘 | Longyi Shao Jinjuan Li Houyin Zhao Shushen Yang Hui Li Weijun Li Tim Jones Keith Sexton Kelly BéruBé | 2007 | Atmospheric Environment2007，，26： | 2 |
| 4 | Growth of Large-size Crystal of PbWO4 by Vertical Bridgman Method with Multi-crucibles显示文摘 | Yang P Liao J Shen B Shao P Hi H Yin Z | 2002 | Journal of Crystal Growth2002，236，： | 2 |
| 5 | Hemolysis of PM_(10) on RBCs in vitro:An indoor air study in a coal-burning lung cancer epidemic area显示文摘Epidemiological studies have suggested that inhalation exposure to indoor ambient air from coal-burning environments is causally associated with respiratory health risks.In order to explore the toxicological mechanisms behind the adverse health effects,the hemolytic activity of PM_(10)(particulate matter with an aerodynamic diameter of 10 um or less)samples collected from homes burning coal in the recognized China'cancer village'Xuanwei were evaluated and matched against their trace elemental contents.The results demonstrated that the hemolytic activity of indoor PM_(10) in coal-burning environments ranged from 4.28%to 5.24%,with a clear positive dose-response relationship.Although low dose samples exhibited a reduced hemolytic activity,PM_(10) could have a toxic effect upon people in a coal-burning indoor environment for extended time periods.The concentrations of analyzed trace elements in PM_(10) samples ranged from 6966 to 12,958 ppm.Among the analyzed elements,Zn,Ti,Ni,Cu,Pb,Ba,Mn,Cr and V were found at higher concentrations and accounted for over 95%of the total elements.The concentrations of total analyzed elements in the PM_(10) samples revealed a significant positive correlation with PM_(10) hemolytic activity.Of the analyzed elements,Zn,Pb and Cs positively correlated with hemolysis,while Li,U and V negatively correlated with the hemolysis of human red blood cells(RBCs).Therefore,the heavy metal elements could be one of the main factors responsible for the hemolytic capacity of indoor PM_(10) in coal-burning environments. | Mengyuan Zhang Longyi Shao Tim Jones Ying Hu Rachel Adams Kelly BéruBé | 2022 | Geoscience Frontiers2022，13，1： | 2 |
| 6 | 冠状动脉内皮功能障碍患者胆固醇流出异常,高密度脂蛋白颗粒物浓度降低显示文摘冠状动脉内皮功能障碍(endothelial dysfunction,ED)是动脉粥样硬化早期标志,增加心血管事件发生风险。该研究假设胆固醇流出容量和高密度脂蛋白颗粒浓度(high-density lipoprotein particle concentration,HDL-PIMA)较高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)更能预测ED。 | 刘莉 叶鹏 Monette JS Hutchins PM Ronsein GE Wimberger J Irwin AD Tang C Sara JD Shao B Vaisar T Lerman A Heinecke JW | 2016 | 中华高血压杂志2016，24，6： | 2 |
| 7 | A study of the copper electrode behavior in borax buffer solutions containing chloride ions and benzotriazole-type inhibitors by voltammetry and the photocurrent response method显示文摘 | ZHOU Guo-ding SHAO Hua Loo B H | 1997 | J Eleetroanal Chem1997，421，12： | 1 |
| 8 | Nonylphenol Ethoxylates and their biodegradation intermediates in water and sludge of a sewage treatment plant显示文摘 | Shao B Hu J Yang M | 2003 | Bull Environ Contam Toxicol2003，70，3： | 1 |
| 9 | Bioreactivity of particulate matter in Beijing air: Results from plasmid DNA assay 显示文摘 | Shao L Y Shi Z B Jones T P | 2006 | Scienceof the Total Environment2006，367，： | 1 |
| 10 | Explosive Consolidation of Amorphous Cobalt-Based Alloys 显示文摘 | Liu Z Y Zhang X T | 1999 | J Mater Process Tech1999，85，： | 1 |
| 11 | Phenolic and triterpenoid glycosides from Aster batangensis 显示文摘 | SHAO Y LI Y L ZHOU B N | 1996 | Phytochemistry1996，41，6： | 1 |
| 12 | Factors influencing the choice of hysterectomy显示文摘 | Shao J B Wong F | 2001 | Aust N I J Obstet Gynecol2001，41，3： | 1 |
| 13 | Occurrence of trace organic contaminants in Bohai Bay and its adjacent Nanpaiwu River,North China显示文摘 | Hu J Y Wan Y Shao B | 2005 | Marine Chemistry2005，95，12： | 1 |
| 14 | Coimmunization of Agaricus blazei Murill extract with hepatitis B virus core protein through DNA vaccine enhances cellular and humoral immune responses 显示文摘 | CHEN L SHAO H J SU Y B | 2004 | International Immunopharmacology2004，4，3： | 1 |
| 15 | Enzymic colorimetry- based DNA chip: a rapid and accurate assay for detecting mu- tations for clarithromycin resistance in the 23S rRNA gene o5 Helicobacter pylori显示文摘 | Xuan SH Zhou YG Shao B | 2009 | J Med Microbiol2009，58，11： | 1 |
| 16 | Quantitative evaluation of precipitates in an A1-Zn-Mg-Cu alloy after isothermal aging 显示文摘 | DU Z W SUN Z M SHAO B L ZHOU T T CHEN C Q | 2006 | Materials Characterization2006，56，： | 1 |
| 17 | Source profiles of volatile organic compounds associated with solvent use in Beijing, China 显示文摘 | Yuan B Shao M Lu S H | 2012 | Atmospheric Environment2012，44，15： | 1 |
| 18 | Optimal redundancy allocation for information technology disaster recovery in the network economy 显示文摘 | Shao B BM | 2005 | IEEE Trans on Dependable and Secure Computing2005，2，3： | 1 |
| 19 | Determination of nonylphenol ethoxylates in the aquatic environment by normal phase liquid chromatography-electrospray mass spectrometry显示文摘 | Shao B Hu J Yang M 2002 | 2002 | J Chromatog A2002，950，： | 1 |
| 20 | E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin al- phaLbeta2-mediated slow leukocyte rolling显示文摘 | Yago T Shao B Miner JJ | 2010 | Blood2010，116，3： | 1 |
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