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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020,28,3: | 516 |
| 2 | Hoare logic-based genetic programming显示文摘Almost all existing genetic programming systems deal with fitness evaluation solely by testing. In this paper, by contrast, we present an original approach that combines genetic programming with Hoare logic with the aid of model checking and finite state automata, henceby proposing a brand new verification-focused formal genetic programming system that makes it possible to evolve reliable programs with mathematically-verified properties. | HE Pei KANG LiShan JOHNSON Colin G YING Shi | 2011 | Science China(Information Sciences)2011,54,3: | 5 |
| 3 | Functional optoacoustic neuro-tomography for scalable whole-brain monitoring of calcium indicators显示文摘Non-invasive observation of spatiotemporal activity of large neural populations distributed over entire brains is a longstanding goal of neuroscience.We developed a volumetric multispectral optoacoustic tomography platform for imaging neural activation deep in scattering brains.It can record 100 volumetric frames per second across scalable fields of view ranging between 50 and 1000 mm^(3) with respective spatial resolution of 35–200μm.Experiments performed in immobilized and freely swimming larvae and in adult zebrafish brains expressing the genetically encoded calcium indicator GCaMP5G demonstrate,for the first time,the fundamental ability to directly track neural dynamics using optoacoustics while overcoming the longstanding penetration barrier of optical imaging in scattering brains.The newly developed platform thus offers unprecedented capabilities for functional whole-brain observations of fast calcium dynamics;in combination with optoacoustics'well-established capacity for resolving vascular hemodynamics,it could open new vistas in the study of neural activity and neurovascular coupling in health and disease. | X Luís Deán-Ben Gali Sela Antonella Lauri Moritz Kneipp Vasilis Ntziachristos Gil G Westmeyer Shy Shoham Daniel Razansky | 2016 | Light(Science & Applications)2016,5,1: | 5 |
| 4 | Rongfriction and wear of low nanometer Si sub 3N sub 4 filled epoxy composites显示文摘 | Shi G Zhang M Q Zhi M | 2003 | Wear2003,254,78: | 3 |
| 5 | Modeling of chemical mechanical polishing with soft pads显示文摘 | Shi F G Zhao B | 1998 | Applied Physics A1998,67,: | 2 |
| 6 | Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis显示文摘 | Kurt Degenhardt Robin Mathew Brian Beaudoin Kevin Bray Diana Anderson Guanghua Chen Chandreyee Mukherjee Yufang Shi Céline Gélinas Yongjun Fan Deirdre A. Nelson Shengkan Jin Eileen White | 2006 | Cancer Cell2006,,1: | 2 |
| 7 | Pathways of N 2 O emission from rice paddy soil显示文摘 | X Yan S Shi L Du G Xing | 2000 | Soil Biology and Biochemistry2000,,3: | 2 |
| 8 | Adhesive joint design for high yield and low cost assembly of fiberoptic devices 显示文摘 | Lin Yaomin Liu Wenning Shi F G | 1992 | IEEE Circuits and Devices Magazine1992,8,6: | 2 |
| 9 | Enthalpy of fusion and equilibrium melting point of the β-form of polypropylene显示文摘 | G Shi B Hung J Zhang | 1984 | Makromol Chem Ripid Commun1984,5,9: | 2 |
| 10 | A DNA vector-based RNAi technology to suppress gene expression in mammalian cells显示文摘 | Sui G Soohoo C Affar el B Gay F Shi Y Forrester W C Shi Y | | 0,,: | 2 |
| 11 | Comparative transcriptome analysis during early fruit development between three seedy citrus genotypes and their seedless mutants显示文摘Identification of genes with differential transcript abundance(GDTA)in seedless mutants may enhance understanding of seedless citrus development.Transcriptome analysis was conducted at three time points during early fruit development(Phase 1)of three seedy citrus genotypes:Fallglo(Bower citrus hybrid(Citrus reticulata×C.reticulata×C.paradisi)×Temple(C.reticulata×C.sinensis)),grapefruit(C.paradisi),Pineapple sweet orange(C.sinensis),and their seedless mutants.Seed abortion in seedless mutants was observed at 26 days post anthesis(Time point 2).Affymetrix transcriptomic analysis revealed 359 to 1077 probe sets with differential transcript abundance in the comparison of seedless versus seedy fruits for each citrus genotypes and time points.The GDTA identified by 18 microarray probe sets were validated by qPCR.Hierarchical clustering analysis revealed a range of GDTA associated with development,hormone and protein metabolism,all of which may reflect genes associated with seedless fruit development.There were 14,9 and 12 genes found exhibiting similar abundance ratios in all three seedless versus seedy genotype comparisons at time point 1,2 and 3,respectively.Among those genes were genes coding for an aspartic protease and a cysteine protease,which may play important roles in seedless fruit development.New insights into seedless citrus fruit development may contribute to biotech approaches to create seedless cultivars. | Shujian Zhang Qingchun Shi Ute Albrecht Robert G Shatters Jr Ric Stange Greg McCollum Shuo Zhang Chengming Fan Ed Stover | 2017 | Horticulture Research2017,4,1: | 2 |
| 12 | Effect of alpha-hederin and sapindoside B on hepatic microsomal cytochrome P-450 in mice 显示文摘 | Shi J Z Liu G T | 1996 | Acta Pharmacol Sin1996,17,3: | 1 |
| 13 | Speciation of heavy metals in marine sediments from the East China Sea by ICP-MS with sequential extraction显示文摘 | Yuan C G Shi J B He B | 2004 | Environment International2004,30,: | 1 |
| 14 | Molecular cloning and tissue expression of porcine heta-defensin-l显示文摘 | Wu H Shi J | 1998 | FEBS Lett1998,424,: | 1 |
| 15 | Acaricidal activities of extracts of Kochia scopatqa against Tetranychus urticae, Tetranychus cinnabarinus, and Tetranychus viennensis (Acari: Tetranychus) 显示文摘 | Shi G L Zhao L L Liu S Q | 2006 | JOURNAL OF ECONOMIC ENTOMOLOGY2006,99,3: | 1 |
| 16 | New synthesis method for nickel phosphide nanoparticles: solid phase reaction of nickel cations with hypophosphites 显示文摘 | Shi G Shen J | 2009 | Journal of Materials Chemistry2009,19,: | 1 |
| 17 | Synthesis of α-Bromo-4-Substituted-Phenone显示文摘 | HU A X HE L M SHI W G | 2004 | Fine Chemicals2004,21,: | 1 |
| 18 | Origin of high bandwidth performance of graded-index plastic optical fibers 显示文摘 | Shi R F Koeppen C Jiang G | 1997 | Appl Phys Left1997,71,: | 1 |
| 19 | Tumor vaccine based on cell surface expression of DcR 3/TR6显示文摘 | Shi G Mao J Zhang J | 2005 | J Immunol2005,174,8: | 1 |
| 20 | A deformation field for Euler-Bernoulli beams with applications to flexible multibody dynamics显示文摘 | Shi P McPhee J Heppler G R | 2001 | Multibody System Dynamics2001,5,: | 1 |