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| 1 | Improving the electrical performance of resistive switching memory using doping technology显示文摘In this paper, improvements of resistive random access memory (RRAM) using doping technology are summarized and analyzed. Based on a Cu/ZrO2/Pt device, three doping technologies with Ti ions, Cu, and Cu nanocrystal, respectively, are adopted in the experiments. Compared to an undoped device, improvements focus on four points: eliminating the electroforming process, reducing operation voltage, improving electrical uniformity, and increasing device yield. In addition, thermal stability of the high resistance state and better retention are also achieved by the doping technology. We demonstrate that doping technology is an effective way of improving the electrical performance of RRAM. | WANG Yan LIU Oi LU HangBing LONG ShiBing WANG Wei LI YingTao ZHANG Sen LIAN WenTai YANG JianHong LIU Ming | 2012 | Chinese Science Bulletin2012，57，11： | 6 |
| 2 | Traditional Chinese Medicine Automated Diagnosis Based on Knowledge Graph Reasoning显示文摘Syndrome differentiation is the core diagnosis method of Traditional Chinese Medicine(TCM).We propose a method that simulates syndrome differentiation through deductive reasoning on a knowledge graph to achieve automated diagnosis in TCM.We analyze the reasoning path patterns from symptom to syndromes on the knowledge graph.There are two kinds of path patterns in the knowledge graph:one-hop and two-hop.The one-hop path pattern maps the symptom to syndromes immediately.The two-hop path pattern maps the symptom to syndromes through the nature of disease,etiology,and pathomechanism to support the diagnostic reasoning.Considering the different support strengths for the knowledge paths in reasoning,we design a dynamic weight mechanism.We utilize Naïve Bayes and TF-IDF to implement the reasoning method and the weighted score calculation.The proposed method reasons the syndrome results by calculating the possibility according to the weighted score of the path in the knowledge graph based on the reasoning path patterns.We evaluate the method with clinical records and clinical practice in hospitals.The preliminary results suggest that the method achieves high performance and can help TCM doctors make better diagnosis decisions in practice.Meanwhile,the method is robust and explainable under the guide of the knowledge graph.It could help TCM physicians,especially primary physicians in rural areas,and provide clinical decision support in clinical practice. | Dezheng Zhang Qi Jia Shibing Yang Xinliang Han Cong Xu Xin Liu Yonghong Xie | 2022 | Computers, Materials & Continua2022，，4： | 4 |
| 3 | Energy Efficiency Optimization for Heterogeneous Cellular Networks Modeled by Matérn Hard-Core Point Process显示文摘The Poisson point process(PPP) has been widely used in wireless network modeling and performance analysis due to the independence between its nodes. Therefore, it may not be a suitable model for many of the exclusive networks between the nodes. This paper analyzes the energy efficiency(EE) and optimizes the two-tier heterogeneous cellular networks(Het Nets). Considering the mutual exclusion between macro base stations(MBSs) distribution, the deployment of MBSs is modeled by the Matérn hard-core point process(MHCPP), and the deployment of pico base stations(PBSs) is modeled by the PPP. We adopt a simple approximation method to study the signal to interference ratio(SIR) distribution in two-tier MHCPP-PPP networks and then derive the coverage probabilities, the average data rates and the energy efficiency of Het Nets. Finally, an optimization algorithm is proposed to improve the EE of Het Nets by controlling the transmit power of PBSs. The simulation results show that the EE of a system can be effectively improved by selecting the appropriate transmit power for the PBSs. In addition, two-tier MHCPP-PPP Het Nets have higher energy efficiency than two-tier PPP-PPP Het Nets. | Yonghong Chen Jie Yang Xuehong Cao Shibing Zhang | 2020 | China Communications2020，17，8： | 4 |
| 4 | A 10×10 deep ultraviolet light-emitting micro-LED array显示文摘In this work,we design and fabricate a deep ultraviolet(DUV)light-emitting array consisting of 10×10 micro-LEDs(μ-LEDs)with each device having 20μm in diameter.Strikingly,the array demonstrates a significant enhancement of total light output power by nearly 52%at the injection current of 100 mA,in comparison to a conventional large LED chip whose emitting area is the same as the array.A much higher(~22%)peak external quantum efficiency,as well as a smaller efficiency droop forμ-LED array,was also achieved.The numerical calculation reveals that the performance boost can be attributed to the higher light extraction efficiency at the edge of eachμ-LED.Additionally,the far-field pattern measurement shows that theμ-LED array possesses a better forward directionality of emission.These findings shed light on the enhancement of the DUV LEDs performance and provide new insights in controlling the light behavior of theμ-LEDs. | Huabin Yu Muhammad Hunain Memon Hongfeng Jia Haochen Zhang Meng Tian Shi Fang Danhao Wang Yang Kang Shudan Xiao Shibing Long Haiding Sun | 2022 | Journal of Semiconductors2022，43，6： | 3 |
| 5 | Analyzing trap generation in silicon-nanocrystal memory devices using capacitance and current measurement显示文摘The combination of capacitance-and current-voltage(CV/IV) measurements is used to analyze trap generation in silicon-nanocrystal memory devices during Fowler-Nordheim(FN) programming/erasing cycling.CV and IV curves are measured after certain P/E cycles.The flatband voltage(Vfb) and the threshold voltage(Vth) are extracted from CV curves by solving one-dimensional Schr?dinger and Poisson equations.Both hole and electron trappings are observed in the tunneling SiO2.They show up in the accumulation and the inversion,respectively.By fitting FN tunneling current,the area densities of cycling-induced electron traps in the blocking oxide and in the tunneling oxide are finally determined. | YANG XiaoNan ZHANG ManHong WANG Yong HUO ZongLiang LONG ShiBing ZHANG Bo LIU Jing LIU Ming | 2012 | Science China(Technological Sciences)2012，55，3： | 3 |
| 6 | miR-20b-5p attenuates hypoxia-induced apoptosis in cardiomyocytes via the HIF-1α/NF-κB pathway显示文摘Chronic hypoxia is a common inducer of end-stage cardiovascular disease.In cells under hypoxia,the hypoxia-inducible factor-1(HIF-1)plays a vital role in regulating downstream target genes.However,the mechanism of hypoxia in card io myocytes is still unclear.In this study,we aimed to identify novel downstream epigenetic targets of HIF-1α in cardiomyocytes under hypoxia.H9c2 cells were exposed to hypoxia condition,and quantitative real-time PCR analysis was performed to evaluate the expression of miR-20b-5p.The results indicated that the expression of miR-20b-5p was down-regulated in H9c2 cells under low oxygen condition.Meanwhile,HIF-1α overexpression further down-regulated the miR-20b-5p expression in H9c2 cells transfected with HIF-1α plasmids.In addition,Annexin-V-FITC/PI flow cytometry analysis suggested that overexpression of miR-20b-5p attenuated cell apoptosis under hypoxia condition in H9c2 cells.Western blot analysis showed that the hypoxia apparently increased Bax and cleaved-caspase-3,but decreased Bcl-2 expression in H9c2 cells,indicating that hypoxia-induced NF-κB signaling pathway activation is mediated by miR-20b-5p.Hypoxia-induced H9c2 cell apoptosis was reduced after HIF-1α knockdown as shown by the flow cytometry analysis.In conclusion,we identified that miR-20b-5p plays an important role in mediating cardiomyocytes apoptosis under hypoxia,which is mediated by the HIF-1/NF-κB signaling pathway. | Zhongquan Zhou Songwen Chen Zhiming Tian Shibing Deng Xuying Yi Shaning Yang Xuexin Yang Lijun Jin Wanqing Shi | 2020 | Acta Biochimica et Biophysica Sinica2020，52，9： | 2 |
| 7 | A Study on the Biocompatibility of MgO Coating Prepared by Anodic Oxidation Method on Magnesium Metal显示文摘Magnesium(Mg),is widely used for the bone repair in oral and orthopedic application due to excellent bioactivity,degradation and biocompatibility.However,the range of application is greatly limited because of the rapid degradation of Mg metal in the body.Surface modification is an effective method to enhance the corrosion resistance and reduce the degradation rate of Mg metal.In the present study,pure Mg metal(P-Mg)was subjected to alkali-heat treatment(AT-Mg)or anodic oxidation-heat treatment(AO-HT-Mg).Both AT-Mg and AO-HT-Mg had a layer of MgO on their surfaces after treatment.Then the effects of MgO coating on corrosion resistance,bioactivity,Mesenchymal Stem Cells’(MSCs)proliferation,adhesion and osteogenic differentiation,and the bone repair capability of Mg metal were investigated.We found both AT-Mg and AO-HT-Mg had stronger corrosion resistance than P-Mg.MSCs on both AT-Mg and AO-HT-Mg had higher expression of proteins and genes of ALP,OCN,Col-I and Runx2 than those on P-Mg.They also showed better bone repair property than P-Mg in vivo.In general,MgO layer formed by anodic oxidation-heat treatment had better resistance and biocompatibility than that produced by alkali-heat treatment.This study indicated the MgO coating not only improved the corrosion resistance of Mg metal,but also promoted the osteogenic differentiation of MSCs and bone regeneration. | Yangmei Chen Xugang Lu Fenghua Zhao Yi Hu Shibing Xiong Yuqiang Guo Ping Huang Bangcheng Yang | 2020 | Journal of Bionic Engineering2020，17，1： | 2 |
| 8 | QoS-Aware Power Allocation Scheme for Relay Satellite Networks显示文摘This paper investigated a QoS-aware power allocation for relay satellite networks.For the given QoS requirements,we analyzed the signal model of relay transmission and formulated the power minimization problem which is non-convex and difficult to solve.To find the optimal solution to the considered problem,we first analyzed the optimization problem and equivalently turn it into a convex optimization problem.Then,we provided a Lagrangian dual-based method to obtain the closed-form of the power allocation and provided an iterative algorithm to the optimal solution.Moreover,we also extended the results to the cooperative transmission mode.Finally,simulation results were provided to verify the superiority of the proposed algorithm. | Jin’ao Yu Xiaogang Tang Shibing Zhu Haopeng Sun Lunxin Zhong Guangyu Yang | 2021 | Journal of Beijing Institute of Technology2021，30，1： | 1 |
| 9 | Fabrication of Cu2S on Cu film electrode and its application in lithium ion bat- tery显示文摘 | Shibing Ni Tao Li Xuelin Yang | 2012 | Thin Solid Fihns2012，520，21： | 1 |
| 10 | Therapeutic effect of Jianpi Liqi Fang(健脾理气方)combined with transcatheter arterial chemoembolization in patients with hepatocellular carcinoma and spleen deficiency syndrome显示文摘OBJECTIVE:To investigate the therapeutic effect of the Jianpi Liqi Fang(健脾理气方,JPLQF)combined with transcatheter arterial chemoembolization(TACE)in patients with hepatocellular carcinoma(HCC)and spleen deficiency syndrome(SDS)and identify a potential indicator of efficacy.METHODS:Ninety-nine patients with HCC who were diagnosed with SDS,non-spleen deficiency syndrome(NSDS),or no syndrome(NS)were treated with JPLQF combined with TACE for three periods.Therapeutic efficacy was compared among the groups.Plasma proteins were screened using label-free discovery analysis and verified via enzyme-linked immunosorbent assay(ELISA).Furthermore,receiver operating characteristic(ROC)curves were analyzed to evaluate therapeutic indicators.RESULTS:After treatment,the Karnofsky Performance Status was significantly improved in the SDS group and significantly better than that in the NS group.The Traditional Chinese Medicine(TCM)syndrome scores were lower in the SDS group after treatment and lower than those in the NSDS group.However,alanine aminotransferase,carbohydrate antigen 19-9,alpha-fetoprotein,and carcinoembryonic antigen levels and white blood cell and platelet counts did not differ among the groups.Serum aspartate aminotransferase levels in the SDS group were significantly lower after treatment than before treatment,and total bilirubin levels were significantly lower in the SDS group than in the NSDS group.Label-free analysis identified 24 differentially expressed proteins(DEPs)between the SDS and NS groups,including 17 and 7 upregulated and downregulated proteins,respectively.Fibulin-5(FBLN5)displayed the largest difference in expression between the groups.ELISA confirmed that FBLN5 levels were significantly lower in the NSDS and NS groups than in the SDS group.Following treatment with JPLQF and TACE,FBLN5 expression was upregulated only in the SDS group.Furthermore,ROC curve analysis indicated that FBLN5 may serve as a potential indicator of the efficacy of JPLQF combined with TACE in patients with HCC and SDS.CONCLUSION:JPLQF combined with TACE improved quality of life,clinical TCM symptoms,and liver function in patients with HCC and SDS.FBLN5 expression was significantly altered by treatment with JPLQF and TACE in patients with HCC and SDS. | CHEN Xiaole WANG Peng MENG Zhiqiang YANG Mengdie ZHOU Wenjun SU Shibing CHEN Jian | 2021 | Journal of Traditional Chinese Medicine2021，41，1： | 1 |
| 11 | Investigation of LRS dependence on the retention of HRS in CBRAM显示文摘 | Xiaoxin Xu Hangbing Lv Hongtao Liu Qing Luo Tiancheng Gong Ming Wang Guoming Wang Meiyun Zhang Yang Li Qi Liu Shibing Long Ming Liu | 2015 | Nanoscale Research Letters2015，，： | 1 |
| 12 | An overview of the switching parameter variation of RRAM显示文摘Resistive random access memory(RRAM) has been considered as one of the most promising candidates for next-generation nonvolatile memory, due to its advantages of simple device structure, excellent scalability, fast operation speed and low power consumption. Deeply understanding the physical mechanism and effectively controlling the statistical variation of switching parameters are the basis of fostering RRAM into commercial application. In this paper, based on the deep understanding on the mechanism of the formation and rupture of conductive filament, we summarize the methods of analyzing and modeling the statistics of switching parameters such as SET/RESET voltage, current, speed or time. Then, we analyze the distributions of switching parameters and the influencing factors. Additionally, we also sum up the analytical model of resistive switching statistics composed of the cell-based percolation model and SET/RESET switching dynamics. The results of the model can successfully explain the experimental distributions of switching parameters of the Ni O- and Hf O2-based RRAM devices. The model also provides theoretical guide on how to improve the uniformity and reliability such as disturb immunity. Finally, some experimental approaches to improve the uniformity of switching parameters are discussed. | Meiyun Zhang Shibing Long Guoming Wang Yang Li Xiaoxin Xu Hongtao Liu Ruoyu Liu Ming Wang Congfei Li Pengxiao Sun Haitao Sun Qi Liu Hangbing L Ming Liu | 2014 | Chinese Science Bulletin2014，59，36： | 1 |
| 13 | Tunnel-Fitted Matching between the Wireless Sensor and Actor Networks and the IPv6 Based on Packet Control显示文摘 | Sheng Yang Shibing Zhu Hui Zhou Yueping Tang Hongjun Li Zhiping Wen | 2010 | 通讯和计算机(中英文版)2010，7，1： | 0 |
| 14 | Energy Efficiency Analysis of Multi-Antenna Cellular Networks with Strategic Sleep Relay显示文摘Energy efficiency(EE) of cellular networks has attracted considerable attention recently. However, EE of relay-assisted cellular networks where the macro base stations(MBSs) are equipped with the multi-antenna has not been thoroughly addressed. This paper considered the downlink transmission of multi-antenna relay-assisted cellular networks, meanwhile, a strategic sleep scheme was used in relay stations(RSs), which dynamically adjusted the RS working mode according to whether the number of users serviced by the relay exceeds a given threshold. A geometric model was built to derive the coverage probability and mean achievable rate from the MBSs to user(UE), the MBS to RS, the RS to UE links and analyze the system EE. It is shown that the energy efficiency of cellular network with strategic sleep RS is slightly higher than that of cellular network with non-sleeping strategy. Furthermore, the MBS equipped with multi-antenna has better impact on energy efficiency and spectral efficiency than the MBS with single antenna. | Yonghong Chen Jie Yang Xuehong Cao Shibing Zhang | 2018 | China Communications2018，15，9： | 0 |
| 15 | Vertical β-Ga_(2)O_(3) power electronics显示文摘β-Ga_(2)O_(3) possesses a highly promising critical electric field of 8 MV/cm,allowing devices with improved perfor-mance compared with other wide bandgap materials[1,2].The 4-inch wafers grown from a melt and over 10μm of the epitax-ial layers grown by Halide vapor phase epitaxy(HVPE)with highly controllable doping concentration,are commercially available,paving the way of vertical power devices.Theβ-Ga_(2)O_(3) community has consistently elevated the average criti-cal electric field superior to SiC or GaN,which is suitable for medium/high voltage infrastructures demanding over 900 V[1].Verticalβ-Ga_(2)O_(3) power electronics have made a tremendous progress in recent years,such as various surface/interface engineering,diverse edge termination,quasi-inversion vertical transistor,etc. | Guangwei Xu Feihong Wu Qi Liu Zhao Han Weibing Hao Jinbo Zhou Xuanze Zhou Shu Yang Shibing Long | 2023 | Journal of Semiconductors2023，44，7： | 0 |
| 16 | A study on the biocompatibility of ramie fibre for medical dressing application显示文摘In order to explore the potential application of Ramie fibre(RF)in medical dressing,the absorbency ratio of ramie fibre cloth,medical gauze and natural cotton fibre cloth was tested,and the factors affecting the absorbency ratio of materials were analysed.Meanwhile,the hemocompatibility of the three fibre materials were also studied.The results showed that the RF cloth had good moisture absorption and hemocompatibility.Therefore,RF is a potential material for medical dressing. | Changsheng Wei Shibing Xiong Siqi Zhang Yifan Cui Simeng Wang Xugang Lu Jun Chen Mei Zhang Bangcheng Yang | 2023 | Biosurface and Biotribology2023，9，4： | 0 |
| 17 | Observation of polarity-switchable photoconductivity in lInitride/MoS_(x)core-shell nanowires显示文摘Ⅱ-Ⅴsemiconductor nanowires are indispensable building blocks for nanoscale electronic and optoelectronic devices.However,solely relying on their intrinsic physical and material properties sometimes limits device functionalities to meet the increasing demands in versatile and complex electronic world.By leveraging the distinctive nature of the one-dimensional geometry and large surface-to-volume ratio of the nanowires,new properties can be attained through monolithic integration of conventional nanowires with other easy-synthesized functional materials.Herein,we combine high-crystal-quality lInitridle nanowires with amorphous molybdenum sulfides(a-MoS)to construct II.nitride/a-MoS_(x) core-shell nanostructures.Upon light ilumination,such nanostructures exhibit striking spectrally distinctive photodetection characteristic in photoelectrochemical environment,demonstrating a negative photoresponsivity of-100.42 mA W^(-1)under 254 nm ilumination,and a positive photoresponsivity of 29.5 mA W^(-1)under 365 nm ilumination.Density functional theory calculations reveal that the successful surface modifcation of the nanowires via a-MoS_(x)decoration accelerates the reaction process at the electrolyte/nanowire interface,leading to the generation of opposite photocurrent signals under different photon ilumination.Most importantly,such polarity-switchable photoconductivity can be further tuned for multiple wavelength bands photodetection by simply adjusting the surrounding environment and/or tailoring the nanowire composition,showing great promise to build light-wavelength controllable sensing devices in the future. | Danhao Wang Wentiao Wu Shi Fang Yang Kang Xiaoning Wang Wei Hu Huabin Yu Haochen Zhang Xin Lu Yuanmin Luo Jr-Hau He Lan Fu Shibing Long Sheng Liu Haiding Sun | 2022 | Light(Science & Applications)2022，11，11： | 0 |
| 18 | Regulation of the Macrophage Phenotype on Titanium Metal by Surface Modification显示文摘The regulation of macrophage phenotype(M1/M2)is very important for tissue repair.The macrophage phenotypes could be affected by the physical and chemical parameters of implant surface.The aim of this study was to investigate the effects of surface modifications of titanium metals on macrophage phenotype.The medical pure titanium metals(PT-Ti)subjected to Anodic Oxidation(AO-Ti),Sand Blasting/acid etching(SLA-Ti)and Plasma-sprayed HA coating(HA coating-Ti)were used for regulating the phenotype of macrophage.The results showed that the Raw264.7 cells of AO-Ti groups had no obvious pseudopodia and could spread evenly in all directions.The levels of IL-1βand TNF-α,which belong to pro-inflammatory genes,expressed by the cells on AO-Ti groups were the lowest among all of the modified titanium groups.But,the levels of IL-10 and TGF-β,which belong to anti-inflammatory genes,expressed on AO-Ti groups were much higher than those on the other groups.Furthermore,the AO-Ti could regulate the expression of SOCS-1 and SOCS-3 to affect the active of NF-κB signaling.The gene expression results of macrophages showed that the AO-Ti was more conductive to inhibit the expression of M1-related genes and promote the expression of M2-related genes in an inflammatory environment.The AO-Ti was more beneficial to tissue repair than other modified titanium metals.The results showed that the anodic oxidation is an effective method to regulate the phenotype of macrophages. | Shibing Xiong Xugang Lu Rui Zuo Ping Huang Bangcheng Yang | 2022 | Journal of Bionic Engineering2022，19，6： | 0 |
| 19 | Affine & Scale-Invariant Heterogeneous Pyramid Features for Automatic Matching of High Resolution Pushbroom Imagery from Chang'e 2 Satellite显示文摘The automatic feature extracting and matching for large amount of linear pushbroom imagery with higher and higher resolution is urgent and challenging in three dimensional reconstructions, remote sensing and mapping. Affine & scale-invariant heterogeneous pyramid feature is proposed in this paper, along with the new scale-invariant analysis method, the detecting of the key points, the affine & scale-invariant descriptor, the steering method of the matching, and the quasi-dense matching algorithm based on the extensive epipolar geometry. The automatic matching is devised for the linear pushbroom imagery. The whole process is executed on lunar images of the highest resolution of ~7 m/pixel(or ~1 m/pixel in the lower orbits) from the Chinese Chang’e 2 satellite, it runs robustly at present, and resulting in large amounts of well-distributed-correspondences with accuracy of 0.3 pixels and excellent reliability, which gives great support for the further exploration both on the Moon and the Earth. | Sheng Yang Shibing Zhu Zhenju Li Xuejun Li Tao Liu Jue Wang Jianwei Xie | 2016 | Journal of Earth Science2016，27，4： | 0 |
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