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| 1 | PEComa of the colon resistant to sirolimus but responsive to doxorubicin/ifosfamide显示文摘A 23-year-old male presented with a three-week-history of crampy abdominal pain and melaena.Colonoscopy revealed a friable mass filling the entire lumen of the cecum;histologically,it was classified as perivascular epithelioid cell tumor(PEComa).An magnetic resonance imaging scan showed,in addition to the primary tumor,two large mesenteric lymph node metastases and four metastatic lesions in the liver.The patient underwent right hemicolectomy and left hemihepatectomy combined with wedge resections of metastases in the right lobe of the liver,the resection status was R0.Subsequently,the patient was treated with sirolimus.After 4 mo of adjuvant mammalian target of rapamycin inhibition he developed two new liver metastases and a local pelvic recurrence.The visible tumor formations were again excised surgically,this time the resection status was R2 with regard to the pelvic recurrence.The patient was treated with 12 cycles of doxorubicin and ifosfamide under which the disease was stable for 9 mo.The clinical course was then determined by rapid tumor growth in the pelvic cavity.Second line chemotherapy with gemcitabine and docetaxel was ineffective,and the patient died 23 mo after the onset of disease.This case report adds evidence that,in malignant PEComa,the mainstay of treatment is curative surgery.If not achievable,the effects of adjuvant or palliative chemotherapy are unpredictable. | Wolfgang Scheppach Nikolaus Reissmann Thomas Sprinz Ekkehard Schippers Bjoern Schoettker Justus G Mueller | 2013 | World Journal of Gastroenterology2013，19，10： | 8 |
| 2 | influence of the normal flora on mu cosal morphology and cellular renewal in the ileum: a comparison of germ-free a nd conventional mice显示文摘 | Abrams GD Bauer H Sprinz H | 1963 | Lab Invest1963，12，： | 1 |
| 3 | Efficiency and mechanism of the antioxidant action of trans-resveratrol and its analogues in the radical liposome oxidation显示文摘 | Stojanovic S Sprinz H Brede O | 2001 | Arch Biochem Biophys2001，391，1： | 1 |
| 4 | Efficiency and mechanism of the antioxidant action of trans -resveratrol and its analogues in the radical li- posome oxidation 显示文摘 | Stojanovie S Sprinz H Brede O | 2001 | Arch Biochem Biophys2001，391，1： | 1 |
| 5 | Sex difference in the CD4^+ CD45^+ R^+ lymphocytes in normal individuals and its selective disease in woman with idiopathic thrombocytopenic purpura显示文摘 | Mylvaganam R Ahn YS Sprinz PG | 1989 | Clin Immunol1989，52，： | 1 |
| 6 | Efficiency and mecha- nism of the antioxidant action of trans-resveratrol and its ana- logues in the radical liposome oxidation 显示文摘 | STOJANVIC S SPRINZ H BREDE O | 2001 | Arch Biochem Bio- phys2001，391，1： | 1 |
| 7 | HIV - asso- ciated lipodystrophy: a review from a Brazilian pers - )ective显示文摘 | Eduardo Sprinz Carlos Bfites Marcelle Alves | 2014 | Therapeutics and Clinical Risk Management2014，17，10： | 1 |
| 8 | Height-age trends from and Arkansas seed source study显示文摘 | Sprinz P T Tabert C B Strub M R | 1989 | For Sci1989，35，： | 1 |
| 9 | Why the United States did not become a party to the Kyoto Protocol:German,Norwegian,and US perspectives显示文摘 | Hovi J Sprinz D F Bang G | | 0，，01： | 1 |
| 10 | Compatible cubic volume and basal area projection equations for thinned old-field loblolly pine plantations 显示文摘 | BURKHART H E SPRINZ P T | 1984 | Forest Science1984，30，1： | 1 |
| 11 | Dietary interven- tion prevents dyslipidemia associated with highly active an- tiretroviral therapy in human immunodeficiency virus type 1- infected individuals: a randomized trial显示文摘 | Lazzaretti RK Kuhmmer R Sprinz E | 2012 | J Am Coil Cardiol2012，59，11： | 1 |
| 12 | Further observations on the effect of surgery on the meniscus of the mandibular joint in rabbits 显示文摘 | Sprinz R | 1961 | Arch Oral Biol1961，5，： | 1 |
| 13 | Zinc protoporphyrin and iron deficiency screening: trends and therapeutic response in an urban pediatric center显示文摘 | Magge H Sprinz P Adams WG | 2013 | JAMA Pediatr2013，167，4： | 1 |
| 14 | Prostaglandin inhibitors in the treatment of single-system Langerhans cell histiocytosis: phar- macologic rationale and report of two cases 显示文摘 | Goldberg SA O'Connor SC Sprinz PG | 2008 | Pediatr Hematol On- col2008，30，10： | 1 |
| 15 | Height-age trendsfrom an Arkansas seed source study显示文摘 | SPRINZ P T TABERT C B STRUB M R | 1989 | For Sci1989，35，3： | 1 |
| 16 | The Interest-Based Explanation of Environmental Policy显示文摘 | Detlef Sprinz Tapani Vaahtoranta | | 0，，01： | 1 |
| 17 | Efficiency and mechanism of the antioxidant action of trans-resveratrol and its analogues in the radical liposome oxidation显示文摘 | Stojanovic S Sprinz H Brede O | 2001 | Arch BioehemBiophys2001，391，1： | 1 |
| 18 | Relationships between tree crown,stem,and stand characteristics in unthinned loblolly pine plantations显示文摘 | Sprinz P T Burkhart H E | 1987 | Can J For Res1987，17，： | 1 |
| 19 | EMciency and mechanism of the antioxidant action ot'trans-resveratrol and its analogues in the radical liposome oxidation显示文摘 | Stojanovic S Sprinz H Brede O | 2001 | Arch Biochem Biophys2001，391，1： | 1 |
| 20 | Efficiency and Mechanism of the Antioxidant Action of trans-Resveratrol and its Analogues in the Radical Liposome Oxidation显示文摘 | Helmut Sprinz | 2001 | Archives of Biochemistry and Biophysics2001，391，1： | 1 |
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