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| 1 | Indocyanine Green-Conjugated Magnetic Prussian Blue Nanoparticles for Synchronous Photothermal/Photodynamic Tumor Therapy显示文摘Indocyanine green(ICG) is capable of inducing a photothermal effect and the production of cytotoxic reactive oxygen species for cancer therapy. However, the major challenge in applying ICG molecules for antitumor therapy is associated with their instability in aqueous conditions and rapid clearance from blood circulation,which causes insufficient bioavailability at the tumor site.Herein, we conjugated ICG molecules with Prussian blue nanoparticles enclosing a Fe_3O_4 nanocore, which was facilitated by cationic polyethyleneimine via electrostatic adsorption. The nanocarrier-loaded ICG formed stable aggregates that enhanced cellular uptake and prevented fluorescence quenching. Moreover, the strong superparamagnetism of the Fe_3O_4 core in the obtained nanocomposites further improved cellular internalization of the drugs guided by a localized magnetic field. The therapeutic efficacy of this nanoplatform was evaluated using tumor models established in nude mice, which demonstrated remarkable tumor ablation in vivo due to strong photothermal/photodynamic effects. This study provides promising evidence that this multifunctional nanoagent might function as an efficient mediator for combining photothermal and photodynamic cancer therapy. | Peng Xue Ruihao Yang Lihong Sun Qian Li Lei Zhang Zhigang Xu Yuejun Kang | 2018 | Nano-Micro Letters2018，10，4： | 3 |
| 2 | Validation of the ABCD3-I Score to Predict Stroke Risk After Transient Ischemic Attack显示文摘 | Bo Song Hui Fang Lu Zhao Yuan Gao Song Tan Jiameng Lu Shilei Sun Avinash Chandra Ruihao Wang Yuming Xu | 2013 | Stroke2013，，5： | 1 |
| 3 | Influence of The Belt and Road Initiative on Oil and Gas Infrastructure显示文摘China has proposed the 'Belt and Road Initiative(B&R)' in 2013. One of its core strategies is international oil/gas cooperation. This paper addresses the status quo of cooperation on oil/gas infrastructure with countries along the line of 'B&R', anticipates the cooperation prospect. On this basis, the author analyzes China's advantages and cooperation basis in this domain, conceives the practical way of cooperation on oil/gas infrastructure with countries along the line of 'B&R'. This paper also elaborates on the potential risks, risk evaluation criteria and risk control in oil/gas infrastructure cooperation with countries along the line of 'B&R'. | Jiang Xinmin Li Mingguang Sun Ruihao | 2016 | China Oil & Gas2016，23，2： | 1 |
| 4 | Interpretation of the “Coal to Gas” Policy显示文摘In order to promote the supply-side structural reform of energy and to improve the quality of the atmospheric environment,the domestic energy industry is vigorously promoting 'coal to gas' projects.While the state government is introducing a series of policies,including environmental protection policies,local governments are also play an active role in introducing relevant policies to promote 'coal to gas.' Currently,there are two main problems confronting the implementation of the 'coal to gas' policy:The first is determining how to ensure a gas supply,and the second is that the price of natural gas is much higher than that of coal and has held back the progress of 'coal to gas.' In terms of future policies and market trends,it is believed that the state will tighten tax laws as well as emission standards,and the use of coal in power generation,the fuel industry,the chemical industry,and other areas will decrease while the demand for natural gas will continue to increase. | Jiang Xinmin Sun Ruihao Shen Huanhuan | 2017 | China Oil & Gas2017，24，1： | 0 |
| 5 | Automatic depression recognition by intelligent speech signal processing:A systematic survey显示文摘Depression has become one of the most common mental illnesses in the world.For better prediction and diagnosis,methods of automatic depression recognition based on speech signal are constantly proposed and updated,with a transition from the early traditional methods based on hand‐crafted features to the application of architectures of deep learning.This paper systematically and precisely outlines the most prominent and up‐to‐date research of automatic depression recognition by intelligent speech signal processing so far.Furthermore,methods for acoustic feature extraction,algorithms for classification and regression,as well as end to end deep models are investigated and analysed.Finally,general trends are summarised and key unresolved issues are identified to be considered in future studies of automatic speech depression recognition. | Pingping Wu Ruihao Wang Han Lin Fanlong Zhang Juan Tu Miao Sun | 2023 | CAAI Transactions on Intelligence Technology2023，8，3： | 0 |
| 6 | Combined molecular docking, homology modeling and DFTmethod for the modification of bovine serum albumin (BSA) toimprove fluorescence spectroscopy for phthalate acid esterschelated with BSA显示文摘While phthalate acid esters(PAEs)cannot fluoresce alone,they can be detected by fluorescence spectroscopy after chelation with bovine serum albumin(BSA).In this study,the types of amino acid residues at the active site of PAEs chelated with BSA were determined using molecular docking technology.A modification scheme of BSA with higher detection sensitivity fluorescence spectroscopy for PAEs was proposed based on the docking results and constructed for a novel BSA structure with a higher detection sensitivity of fluorescence spectroscopy using a homologous modeling method.Density functional theory(DFT)was employed to explore the influence before and after BSA modification on PAEs’detection through fluorescence spectroscopy.The results showed that the docking scores between BSAs and dimethyl phthalate(DMP),dibutyl phthalate(DBP)and di-n-octyl phthalate(DNOP)were increased up to 26.45%,16.82%and 16.30%,respectively,indicating that the active site modification of BSA could enhance the binding affinity between BSA and PAEs.The fluorescence intensity of PAEs chelated with modified BSAs were calculated.The fluorescence intensity of fluorescence spectroscopy for DMP,DBP and DNOP chelated with BSAs after modification was increased up to 2.8-,104.51-and 62.43-fold,respectively,which achieved the purpose of theoretically modifying BSA to improve the detection sensitivity of fluorescence spectroscopy for PAEs. | MINGHAO LI YOULI QIU WENHUI ZHANG RUIHAO SUN MEIJIN DU LUZE YANG YU LI | 2020 | BIOCELL2020，44，2： | 0 |
| 7 | Temperature-field history dependence of the elastocaloric effect for a strain glass alloy显示文摘The singular change of the order parameter at the first order martensitic transformation(MT)temperature restricts the caloric response to a narrow temperature range.Here the MT is tuned into a sluggish strain glass transition by defect doping and a large elastocaloric effect appears in a wide temperature range.Moreover,an inverse elastocaloric effect is observed in the strain glass alloy with history of zerofield cooling and is attributed to the slow dynamics of the nanodomains in response to the external stress.This study offers a design recipe to expand the temperature range for good elastocaloric effect. | Deqing Xue Ruihao Yuan Yuanchao Yang Jianbo Pang Yumei Zhou Xiangdong Ding Turab Lookman Xiaobing Ren Jun Sun Dezhen Xue | 2022 | Journal of Materials Science & Technology2022，，8： | 0 |
| 8 | Promoting Systematic Transformation of China’s Economy and Society under the Goal of Carbon Neutrality and Peaking Carbon Dioxide Emissions显示文摘Since September 2020,President Xi Jinping has reiterated to the world that China will achieve the goal to peak carbon dioxide emissions by 2030 and achieve carbon neutrality by 2060,which reflects China’s role as a great power in coping with global climate change and highlights China’s determination to accelerate green and low-carbon development. | Jiang Xinmin Sun Ruihao | 2021 | China Oil & Gas2021，28，1： | 0 |
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