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| 1 | Treatment strategy for gastric non-invasive intraepithelial neoplasia diagnosed by endoscopic biopsy显示文摘Treatment strategies,whether as follow-up or'total incisional biopsy'for gastric noninvasive intraepithelial neoplasia diagnosed by examination of an endoscopic forceps biopsy specimen,are controversial due to problems associated with the diagnostic accuracy of endoscopic forceps biopsy and questions about the safety and efficacy of endoscopic treatment.Based on the histological findings of the biopsy specimen,it is difficult to differentiate between reactive or regenerative changes,inflammation and neoplastic changes,intraepithelial and invasive tumors.Therefore,gastric neoplasia diagnosed as noninvasive intraepithelial often develop into invasive carcinoma during follow-up.Recent advances in endoscopic modalities and treatment devices,such as image-enhanced endoscopy and highfrequency generators,may make endoscopic treatment,such as endoscopic submucosal dissection(ESD),a therapeutic option for gastric intraepithelial neoplasia,including low-grade neoplasms.Future studies are required to evaluate whether ESD is a valid strategy for gastric intraepithelial neoplasm with regard to safety and cost effectiveness. | Tsutomu Nishida Shusaku Tsutsui Motohiko Kato Takuya Inoue Shunsuke Yamamoto Yoshito Hayashi Tomofumi Akasaka Takuya Yamada Shinichiro Shinzaki Hideki Iijima Masahiko Tsujii Tetsuo Takehara | 2011 | World Journal of Gastrointestinal Pathophysiology2011,2,6: | 18 |
| 2 | Molecular, Functional, and Structural Imaging of Major Depressive Disorder显示文摘Major depressive disorder(MDD) is a significant cause of morbidity and mortality worldwide,correlating with genetic susceptibility and environmental risk factors.Molecular,functional,and structural imaging approaches have been increasingly used to detect neurobiological changes,analyze neurochemical correlates,and parse pathophysiological mechanisms underlying MDD.We reviewed recent neuroimaging publications on MDD in terms of molecular,functional,and structural alterations as detected mainly by magnetic resonance imaging(MRI) and positron emission tomography.Altered structure and function of brain regions involved in the cognitive control of affective state have been demonstrated.An abnormal default mode network,as revealed by resting-state functional MRI,is likely associated with aberrant metabolicand serotonergic function revealed by radionuclide imaging.Further multi-modal investigations are essential to clarify the characteristics of the cortical network and serotonergic system associated with behavioral and genetic variations in MDD. | Kai Zhang Yunqi Zhu Yuankai Zhu Shuang Wu Hao Liu Wei Zhang Caiyun Xu Hong Zhang Takuya Hayashi Mei Tian | 2016 | Neuroscience Bulletin2016,32,3: | 9 |
| 3 | Choroidal and cutaneous metastasis from gastric adenocarcinoma显示文摘Choroidal or cutaneous metastasis of gastric cancer is rare. Gastrointestinal cancer was found in only 4% in patients with uveal metastasis. Choroidal metastasis from gastric cancer was reported in two cases in earlier literature. The frequency of gastric cancer as a primary lesion was 6% in cutaneous metastasis of men, and cutaneous metastasis occurs in 0.8% of all gastric cancers. We report a patient with gastric adenocarcinoma who presented with visual disorder in his left eye and skin pain on his head as his initial symptoms. These symptoms were diagnosed to be caused by choroidal and cutaneous metastasis of gastric adenocarcinoma. Two cycles of chemotherapy consisted of oral S-1 and intravenous cisplatin (SPIRITS regimen); this was markedly effective to reduce the primary gastric lesion and almost all the metastatic lesions. | Shoichiro Kawai Tsutomu Nishida Yoshito Hayashi Hisao Ezaki Takuya Yamada Shinichiro Shinzaki Masanori Miyazaki Kei Nakai Takayuki Yakushijin Kenji Watabe Hideki Iijima Masahiko Tsujii Kohji Nishida Tetsuo Takehara | 2013 | World Journal of Gastroenterology2013,19,9: | 6 |
| 4 | Important roles of graphene edges in carbon-based energy storage devices显示文摘Nanostructured carbon materials, including carbon nanotubes, graphene and nanoporous carbon, show promise for expanding renewable energy. In particular, the configuration and electronic properties of graphene edges in relation with their electrochemical activity have become a major issue in carbon-based energy storage devices. Here, we review recent results concerning the important roles of graphene edges as the gateway for lithium ion intercalation in the anode of lithium-ion batteries, as promoters of high capacitance in carbon-based supercapacitors, and as anchoring sites for Pt nanoparticles in fuel cells. We envisage that the controlled synthesis of a specific, clean, and stable edge configuration could be achieved to maximize the electrochemical performance of nanostructured carbon-based energy storage devices. | Yoong Ahm Kim Takuya Hayashi Jin Hee Kim Morinobu Endo | 2013 | Journal of Energy Chemistry2013,22,2: | 2 |
| 5 | Molecular genetic analysis of deep-seated glioblastomas显示文摘 | Yutaka Hayashi Junkoh Yamashita Takuya Watanabe | 2004 | Cancer Genetics and Cytogenetics2004,153,1: | 1 |
| 6 | Local Resection by Combined Laparoendoscopic Surgery for Duodenal Gastrointestinal Stromal Tumor显示文摘 | Motohiko Kato Kiyokazu Nakajima Toshirou Nishida Makoto Yamasaki Tsutomu Nishida Shusaku Tsutsui Hideharu Ogiyama Shunsuke Yamamoto Takuya Yamada Masaki Mori Yuichiro Doki Norio Hayashi Isidoro Di Carlo | 2011 | Diagnostic and Therapeutic Endoscopy2011,,: | 1 |
| 7 | Comparative study of herringbone and stacked-cup carbon nanofibers显示文摘 | Yoong Ahm Kim Takuya Hayashi | 2005 | Carbon2005,43,: | 1 |
| 8 | Thrombocytopenia Exacerbates Cholestasis-Induced Liver Fibrosis in Mice显示文摘 | Takahiro Kodama Tetsuo Takehara Hayato Hikita Satoshi Shimizu Wei Li Takuya Miyagi Atsushi Hosui Tomohide Tatsumi Hisashi Ishida Seiji Tadokoro Akio Ido Hirohito Tsubouchi Norio Hayashi | 2010 | Gastroenterology2010,,7: | 1 |
| 9 | Usefulness of clip traction in the early phase of esophageal endoscopic submucosal dissection显示文摘 | Masaho Ota Tsutomu Nakamura Kazuhiko Hayashi Takeshi Ohki Kousuke Narumiya Takuya Sato Yuji Shirai Kenji Kudo Masakazu Yamamoto | 2012 | Digestive Endoscopy2012,,5: | 1 |
| 10 | Impact of reduced left atrial functions on diagnosis of paroxysmal atrial fibrillation: Results from analysis of time-left atrial volume curve determined by two-dimensional speckle tracking显示文摘 | Mika Mori Hideaki Kanzaki Makoto Amaki Takahiro Ohara Takuya Hasegawa Hiroyuki Takahama Kazuhiko Hashimura Tetsuo Konno Kenshi Hayashi Masakazu Yamagishi Masafumi Kitakaze | 2011 | Journal of Cardiology2011,,1: | 1 |
| 11 | Interferon-α suppresses hepatitis B virus enhancer II activity via the protein kinase C pathway显示文摘 | Takatoshi Nawa Hisashi Ishida Tomohide Tatsumi Wei Li Satoshi Shimizu Takahiro Kodama Hayato Hikita Atsushi Hosui Takuya Miyagi Tatsuya Kanto Naoki Hiramatsu Norio Hayashi Tetsuo Takehara | 2012 | Virology2012,,2: | 1 |
| 12 | Isolation and tyrosin ase inhibitory effects of polyphenols from the leaves of persimmon Diospyros kaki显示文摘 | XUE Y L TAKUYA M HAYASHI Y | 2011 | Journal of Agricultural and Food Chemistry2011,59,: | 1 |
| 13 | Altered interferon-α-signaling in natural killer cells from patients with chronic hepatitis C virus infection显示文摘 | Takuya Miyagi Tetsuo Takehara Kumiko Nishio Satoshi Shimizu Keisuke Kohga Wei Li Tomohide Tatsumi Naoki Hiramatsu Tatsuya Kanto Norio Hayashi | 2010 | Journal of Hepatology2010,,3: | 1 |
| 14 | Usefulness of clip traction in the early phase of esophageal endoscopic submucosal dissection显示文摘 | Masaho Ota Tsutomu Nakamura Kazuhiko Hayashi Takeshi Ohki Kousuke Narumiya Takuya Sato Yuji Shirai Kenji Kudo Masakazu Yamamoto | 2012 | Digestive Endoscopy2012,,5: | 1 |
| 15 | Usefulness of EUS combined with contrast-enhancement in the differential diagnosis of malignant versus benign and preoperative localization of pancreatic endocrine tumors显示文摘 | Takuya Ishikawa Akihiro Itoh Hiroki Kawashima Eizaburo Ohno Hiroshi Matsubara Yuya Itoh Yosuke Nakamura Masanao Nakamura Ryoji Miyahara Kazuhiko Hayashi Masatoshi Ishigami Yoshiaki Katano Naoki Ohmiya Hidemi Goto Yoshiki Hirooka | 2010 | Gastrointestinal Endoscopy2010,,6: | 1 |
| 16 | Evaluation of Endoscopic Ultrasound Image Quality Is Necessary in Endosonographic Assessment of Early Gastric Cancer Invasion Depth显示文摘 | Shunsuke Yamamoto Tsutomu Nishida Motohiko Kato Takuya Inoue Yoshito Hayashi Jumpei Kondo Tomofumi Akasaka Takuya Yamada Shinichiro Shinzaki Hideki Iijima Masahiko Tsujii Tetsuo Takehara Salem Omar | 2012 | <journal-title>Gastroenterology Research and Practice2012,,: | 1 |
| 17 | Effects of rosuvastatin on serum lipids and arteriosclerosis in dyslipidemic patients with cerebral infarction显示文摘 | Ichiro Deguchi Yohsuke Horiuchi Takeshi Hayashi Yoshihide Sehara Yuji Kato Yasuko Ohe Takuya Fukuoka Hajime Maruyama Hiroyasu Sano Yuito Nagamine Norio Tanahashi | 2014 | Journal of Stroke and Cerebrovascular Diseases2014,,: | 1 |
| 18 | Guidance for peptide vaccines for the treatment of cancer显示文摘 | Yoshiyuki Yamaguchi Hiroki Yamaue Takuji Okusaka Kiyotaka Okuno Hiroyuki Suzuki Tomoaki Fujioka Atsushi Otsu Yasuo Ohashi Rumiko Shimazawa Kazuto Nishio Junji Furuse Hironobu Minami Takuya Tsunoda Yuzo Hayashi Yusuke Nakamura | 2014 | Cancer Sci2014,,: | 1 |
| 19 | Effects of nitric oxide on mucosal barrier dysfunction during early phase of intestinal ischemia/reperfusion显示文摘 | Yusuke Takizawa Hisanao Kishimoto Takuya Kitazato Mikio Tomita Masahiro Hayashi | | European Journal of Pharmaceutical Sciences0,,: | 1 |
| 20 | Clinicopathological Features of Recurrence in Patients After 10-year Disease-free Survival Following Curative Hepatic Resection of Hepatocellular Carcinoma显示文摘 | Masaki Kaibori Shoji Kubo Hiroaki Nagano Michihiro Hayashi Seiji Haji Takuya Nakai Morihiko Ishizaki Kosuke Matsui Takahiro Uenishi Shigekazu Takemura Hiroshi Wada Shigeru Marubashi Koji Komeda Fumitoshi Hirokawa Yasuyuki Nakata Kazuhisa Uchiyama A-Hon Kw | 2013 | World Journal of Surgery2013,,4: | 1 |