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| 1 | 厌氧真菌体外发酵筛选技术的研究显示文摘分离自不同地区、不同动物的 30株厌氧真菌菌株分两次进行发酵降解试验。发酵底物为麦秸 ,其干物质含量为 5g·L-1,利用气压转换技术测定菌株发酵的产气量。试验Ⅰ 10个菌株降解麦秸所得的表观干物质消失率为 46 6~ 5 79mg·g-1,总产气量为 110~ 15 0mL。试验Ⅱ 2 0个菌株的表观干物质消失率为 386~ 5 94mg·g-1,总产气量为 99~ 144mL。两次试验中共有 2 4个菌株的总产气量与表观干物质消失率成正相关 ,相关系数 (R2 )分别为 0 917和 0 90 3。除菌株W 6外 ,2 9个菌株在 1/ 2气体总量时的生长速率相似 ,为 0 0 32~ 0 0 42h-1。菌株W 6的生长速率为 0 0 2 5h-1。 30个菌株的延滞期为 15 4~ 30 2h。结果说明 ,利用气压转化技术测定发酵产气量能方便有效地用于厌氧真菌生长动力学的比较和菌株的筛选 。 | 朱伟云 毛胜勇 王全军 姚文 M K Theodorou | 2001 | 南京农业大学学报2001，24，3： | 25 |
| 2 | Protective effects of ischemic preconditioning and application of lipoic acid prior to 90 min of hepatic ischemia in a rat model显示文摘AIM: To compare different preconditioning strategies to protect the liver from ischemia/reperfusion injury focusing on the expression of pro- and anti-apoptotic proteins. Interventions comprised different modes of ischemic preconditioning (IP) as well as pharmacologic pretreatment by α-lipoic acid (LA). METHODS: Several groups of rats were compared: sham operated animals, non-pretreated animals (nt), animals receiving IP (10 min of ischemia by clamping of the portal triad and 10 min of reperfusion) prior to sustained ischemia, animals receiving selective ischemic preconditioning (IPsel, 10 min of ischemia by selective clamping of the ischemic lobe and 10 min of reperfusion) prior to sustained ichemia, and animals receiving 500 μmol α-LA injected i.v. 15 min prior to the induction of 90 min of selective ischemia. RESULTS: Cellular damage was decreased only in the LA group. TUNEL-positive hepatocytes as well as necrotic hepatocyte injury were also decreased only by LA (19 ± 2 vs 10 ± 1, P < 0.05 and 29 ± 5 vs 12 ± 1, P < 0.05). Whereas caspase 3- activities in liver tissue were unchanged, caspase 9- activity in liver tissue was decreased only by LA pretreatment (3.1 ± 0.3 vs 1.8 ± 0.2, P < 0.05). Survival rate as the endpoint of liver function was increased after IP and LA pretreatment but not after IPsel. Levels of lipid peroxidation (LPO) in liver tissue were decreased in the IP as well as in the LA group compared to the nt group. Determination of pro- and anti-apoptotic proteins showed a shift towardsanti-apoptotic proteins by LA. In contrast, both our IP strategies failed to influence apototic cell death. CONCLUSION: IP, consisting of 10 min of ischemia and 10 min of reperfusion, protects only partly against ischemia/reperfusion injury of the liver prior to 90 min of selective ischemia. IPsel did not influence ischemic tolerance of the liver. LA improved tolerance to ischemia, possibly by downregulation of pro-apoptotic Bax. | Friedrich Duenschede Kirsten Erbes Nina Riegler Patrick Ewald Achim Kircher Stefanie Westermann Arno Schad Imke Miesmer Simon Albrecht-Schck Ines Gockel Alexandra K Kiemer Theodor Junginger | 2007 | World Journal of Gastroenterology2007，13，27： | 8 |
| 3 | Patterns of in-hospital mortality and bleeding complications following PCI for very elderly patients: insights from the Dartmouth Dynamic Registry显示文摘BackgroundVery 老病人(年龄 85 年) 是人口的一个很快增加的片断。作为一个组,他们经历跟随经皮的冠的干预(一种总线标准) 的在里面医院死亡和流血复杂并发症的高率。然而,在流血和死亡在之间的关系老 unknown.MethodsRetrospective 评论在 Dartmouth-Hitchcock 从 2000 ~ 2015 在 17,378 连续一种总线标准过程上被执行医学中心。在索引一种总线标准承认期间流血的发生(流血要求的输送,存取地点 hematoma > 5 厘米, pseudoaneurysm,和 retroperitoneal 流血)? 并且在里面医院死亡为四个年龄组被报导(< 65 年, 65-74 年, 75-84 年,和 85 年) 。承受了谁的流血复杂并发症和那些的病人的死亡被计算, multivariate 分析为在里面医院被执行死亡。最后,知道流血的预言者在病人年龄之间被比较 < 85 年和年龄 17,378 个病人学习了的 85 years.ResultsOf,(5.9%) 1019 经历了流血,(2.1%) 369 死了在里面医院追随者一种总线标准。流血和在里面医院死亡的发生与增加年龄 monotonically 增加了(死亡:0.94% , 2.27% , 4.24% 和 4.58% ;流血:3.96% , 6.62% , 10.68% 和 13.99% 好久 < 65, 65-74, 75-84 和 85 年,分别地) 。除了病人年龄 85 年,在 multivariate 分析上,流血为所有年龄组与增加的死亡被联系[机会比率(95% CI ) :变老 < 65 年, 3.65 (1.99-6.74 ) ;年龄 65-74 年, 2.83 (1.62-4.94 ) ;年龄 75-84 年, 3.86 (2.56-5.82 ) ,年龄 85 年:1.39 (0.49-3.95 )] 有增加的 .ConclusionsBleeding 和死亡追随者一种总线标准增加变老。为老尽管有流血的高率,流血在里面医院死亡追随者一种总线标准不再是预兆的。 | Shawn X Li Hannah I Chaudry Jiyong Lee Theodore B Curran Vishesh Kumar Kendrew K Wong Bruce W Andrus James T DeVries | 2018 | Journal of Geriatric Cardiology2018，15，2： | 6 |
| 4 | Reduction of ischemia reperfusion injury after liver resection and hepatic inflow occlusion by α-lipoic acid in humans显示文摘AIM: To evaluate the protective effects of precondition- ing by α-lipoic acid (LA) in patients undergoing hepatic resection under inflow occlusion of the liver. METHODS: Twenty-four patients undergoing liver re- section for various reasons either received 600 mg LA or NaCl 15 min before transection performed under inflow occlusion of the liver. Blood samples and liver wedge bi- opsy samples were obtained after opening of the abdo- men immediately after inflow occlusion of the liver, and 30 min after the end of inflow occlusion of the liver. RESULTS: Serum levels of aspartate transferase and alanine transferase were reduced at all time points in patients who received LA in comparison to those who received NaCL. This was accompanied by reduced histo- morphological features of oncosis. We observed TUNEL- positive hepatocytes in the livers of the untreated patients, especially after 30 min of ischemia. LA attenu- ated this increase of TUNEL-positive hepatocytes. Under preconditioning with LA, ATP content was significantly enhanced after 30 min of ischemia and after 30 min of reperfusion. CONCLUSION: This is the first report on the poten- tial for LA reducing ischemia/reperfusion injury (IRI) of the liver in humans who were undergoing liver surgery. Beside its simple and rapid application, side effects did not occur. LA might therefore represent a new strategy against hepatic IRI in humans. | Fritz Dünschede Kirsten Erbes Achim Kircher Stefanie Westermann Joachim Seifert Arno Schad Kempski Oliver Alexandra K Kiemer Junginger Theodor | 2006 | World Journal of Gastroenterology2006，12，42： | 6 |
| 5 | Quality in the technical performance of colonoscopy and the continuous quality improvement process for colonoscopy: recommendations of the U.S. Multi-Society Task Force on Colorectal Cancer显示文摘 | Douglas K Rex John H Bond Sidney Winawer Theodore R Levin Randall W Burt David A Johnson Lynne M Kirk Scott Litlin David A Lieberman Jerome D Waye James Church John B Marshall Robert H Riddell | 2002 | The American Journal of Gastroenterology2002，，6： | 3 |
| 6 | A semi-automated in vitro gas production technique for ruminant feedstuff evaluation显示文摘 | Rogerio M Mauricio Fergus L Mould Mewa S Dhanoa Emyr Owen Kulwant S Channa Michael K Theodorou | 1999 | Animal Feed Science and Technology1999，，4： | 2 |
| 7 | Diagnosis and endoscopic treatment of esophago-bronchial fistula due to gastric heterotopy显示文摘Heterotopic gastric mucosa patches are congenital gastrointestinal abnormalities and have been reported to occur anywhere along the gastrointestinal tract from mouth to anus.Complications of heterotopic gastric mucosa include dysphagia,upper gastrointestinal bleeding,upper esophageal ring stricture,adenocarcinoma and fistula formation.In this case report we describe the diagnosis and treatment of the first case of esophago-bronchial fistula due to heterotopic gastric mucosa in mid esophagus.A 40-year old former professional soccer player was referred to our department for treatment of an esophago-bronchial fistula.Microscopic examination of the biopsies taken from the esophageal fistula revealed the presence of gastric heterotopic mucosa.We decided to do a non-surgical therapeutic endoscopic procedure.A sclerotherapy catheter was inserted through which 1 mL of ready to use synthetic surgical glue was applied in the fistula and it closed the fistula opening with excellent results. | Konstantinos H Katsanos Dimitrios K Christodoulou Sevasti Kamina Kosmidou Maria Evangelia Lambri Stavroula Theodorou Konstantinos Tsampoulas Mitsi Vasiliki Epameinondas V Tsianos | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，4： | 2 |
| 8 | Growth of anaerobic rumen fungi on defined and semi-defined media lacking rumen fluid显示文摘 | LOWE S E THEODOROU M K TRINCI A P J | 1985 | Journal of General Microbiology1985，131，： | 1 |
| 9 | The Gradient of the Finite Element Variational Indicator with Respect to NodalPoint co-ordinates: an Explicit Calculation and Applications in Fracture Mechanics and Mesh Optimization显示文摘 | Theodore Sussman Bathe K J | 1985 | International Journal for Numerical Methods in Engineering1985，21，6： | 1 |
| 10 | Tigecyeline for the Treatment of Mul- tidrug Resisdant (Including Carbapeneu Resistant) Acineto- baeter Infections: A Review of Scientific Evidence显示文摘 | Drosos E Theodore K | 2008 | J Amti- mierob Chemother2008，62，： | 1 |
| 11 | Isolation, characterization and properties of the oversulphated chondroitin sulphate proteoglycan from squid skin with peculiar glycosaminoglycan sulphation pattern显示文摘 | Karamanos Nikos K Aletras Alexis J Tsegenidis Theodore | 1992 | Eur J Biochem1992，204，： | 1 |
| 12 | Enu- meration of anaerobicchytridiomycetes as thallus forming units:novel method for quantification of fi- brolytic fungal populations from the digestive tract ecosystem显示文摘 | Theodorou M K Gill M King Spooner | 1990 | Applied and Environmental Microbi- ology1990，，56： | 1 |
| 13 | Social stigmatization and hepatitis C virus infection显示文摘 | Zacks S Beavers K Theodore D | 2006 | Journal of Clinical Gastroenterology2006，40，3： | 1 |
| 14 | Risk analysis based LNG facility siting standard in NFPA 59A显示文摘 | RAJ P K LEMOFF THEODORE | 2009 | Journal of Loss Prevention in the Process Industries2009，，22： | 1 |
| 15 | Adverse effects associated with physical restraint 显示文摘 | Wanda K Mohr Theodore A Petti Brian D Mohr | 2003 | Can J Psychiatry2003，48，5： | 1 |
| 16 | Finite Element Analysis of Steel Beam to Column Connections Subjected to Blast Loads 显示文摘 | TAPAN S DANIEL L THEODOR K | 2005 | International Journal of Impact Engineering2005，31，2005： | 1 |
| 17 | Excitation-emission-matrix fluorescence spectroscopy applied to humic acid bands in coral reefs显示文摘 | Matthews B J H Jones A C Theodorou N K | 1996 | Mar Chem1996，55，34： | 1 |
| 18 | Small cell carcinoma arising in Barrett' s esophagus: a case report and review of the literature显示文摘 | MARKOGIANNAKIS H THEODOROU D TOUTOUZAS K G | 2008 | J Med Case Reports2008，2，1： | 1 |
| 19 | Non-starch polysaccharide composition and in vitro fermentability of tropical forage legumes varying in phenolic content显示文摘 | Longland A Theodorou M K Sanderson R | 1994 | Animal Feed Science and Technology1994，55，3： | 1 |
| 20 | A simple gas production method using a pressure transducer to determin the fermentation kinetics of ruminant feeds 显示文摘 | Theodorou M K Williams B A Dhanoa M S | 1994 | Animal Feed Science and Technology1994，48，： | 1 |
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