|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Particle-size-dependent upconversion luminescence of NaYF4:Yb,Er nanoparticles in organic solvents and water at different excitation power densities显示文摘A systematic study of the luminescence properties of monodisperse β-NaYF4: 20%Yb^3+,2%Er^3+ upconversion nanoparticles (UCNPs)with sizes ranging from 12--43nm is presented utilizing steady-state and time-resolved fluorometry. Special emphasis was dedicated to the absolute quantification of size-and environment-induced quenching of upconversion luminescence (UCL)by highenergy O-H and C-H vibrations from solvent and ligand molecules at different excitation power densities (P).In this context,the still-debated population pathways of the 4F9/2 energy level of Er^3+ were examined.Our results highlight the potential of particle size and P value for color tuning based on the pronounced near-infrared emission of 12nm UCNPs,which outweighs the red Er^3+emission under 'strongly quenched'conditions and accounts for over 50% of total UCL in water.Because current rate equation models do not include such emissions,the suitability of these models for accurately simulating all (de)population pathways of small UCNPs must be critically assessed.Furthermore,we postulate population pathways for the 4F9/2energy level of Er3.,Which correlate with the size-,environment-,and P-dependent quenching states of the higher Er^3+ energy levels. | Marco Kraft Christian Würth Verena Muhr Thomas Hirsch Ute Resch-Genger | 2018 | Nano Research2018，11，12： | 8 |
| 2 | Gynecologic oncologists involvement on ovarian cancer standard of care receipt and survival显示文摘AIM:To examine the influence of gynecologic oncolo-gists(GO) in the United States on surgical/chemotherapeutic standard of care(SOC), and how this translates into improved survival among women with ovarian cancer(OC).METHODS: Surveillance, Epidemiology, and End Result(SEER)-Medicare data were used to identify 11688 OC patients(1992-2006). Only Medicare recipients with an initial surgical procedure code(n = 6714) were included. Physician specialty was identified by linking SEER-Medicare to the American Medical Association Masterfile. SOC was defined by a panel of GOs. Multivariate logistic regression was used to determine predictors of receiving surgical/chemotherapeutic SOCand proportional hazards modeling to estimate the effect of SOC treatment and physician specialty on survival. RESULTS: About 34% received surgery from a GO and 25% received the overall SOC. One-third of women had a GO involved sometime during their care. Women receiving surgery from a GO vs non-GO had 2.35 times the odds of receiving the surgical SOC and 1.25 times the odds of receiving chemotherapeutic SOC(P < 0.01). Risk of mortality was greater among women not receiving surgical SOC compared to those who did [hazard ratio = 1.22(95%CI: 1.12-1.33), P < 0.01], and also was higher among women seen by non-GOs vs GOs(for surgical treatment) after adjusting for covariates. Median survival time was 14 mo longer for women receiving combined SOC. CONCLUSION: A survival advantage associated with receiving surgical SOC and overall treatment by a GO is supported. Persistent survival differences, particularly among those not receiving the SOC, require further investigation. | Sun Hee Rim Shawn Hirsch Cheryll C Thomas Wendy R Brewster Darryl Cooney Trevor D Thompson Sherri L Stewart | 2016 | World Journal of Obstetrics and Gynecology2016，5，2： | 3 |
| 3 | Multiband emission from single β-NaYF_(4)(Yb,Er) nanoparticles at high excitation power densities and comparison to ensemble studies显示文摘Ensemble and single particle studies of the excitation power density (P)-dependent upconversion luminescence (UCL) of core and core-shell β-NaYF_(4):Yb,Er upconversion nanoparticles (UCNPs) doped with 20% Yb^(3+) and 1% or 3% Er^(^(3+)) performed over a P regime of 6 orders of magnitude reveal an increasing contribution of the emission from high energy Er^(3+) levels at P > 1 kW/cm^(2). This changes the overall emission color from initially green over yellow to white. While initially the green and with increasing P the red emission dominate in ensemble measurements at P < 1 kW/cm^(2), the increasing population of higher Er^(^(3+)) energy levels by multiphotonic processes at higher P in single particle studies results in a multitude of emission bands in the ultraviolet/visible/near infrared (UV/vis/NIR) accompanied by a decreased contribution of the red luminescence. Based upon a thorough analysis of the P-dependence of UCL, the emission bands activated at high P were grouped and assigned to 2–3, 3–4, and 4 photonic processes involving energy transfer (ET), excited-state absorption (ESA), cross-relaxation (CR), back energy transfer (BET), and non-radiative relaxation processes (nRP). This underlines the P-tunability of UCNP brightness and color and highlights the potential of P-dependent measurements for mechanistic studies required to manifest the population pathways of the different Er^(3+) levels. | Florian Frenzel Christian Würth Oleksii Dukhno Frédéric Przybilla Lisa MWiesholler Verena Muhr Thomas Hirsch Yves Mély Ute Resch-Genger | 2021 | Nano Research2021，14，11： | 3 |
| 4 | Size and time dependent internalization of label-free nano-graphene oxide in human macrophages显示文摘Graphene 氧化物为生物医学的应用作为材料显示出大诺言,例如,一个多药交货平台。与这在看法,在 nanosized graphene 氧化物薄片和生物房间之间的相互作用上的研究的报告开始正在出现。然而,限制,并且最使用了的研究遗体的数字标记 graphene 为氧化物样品在 endocytosis 之上追踪材料。不幸地,标记的过程改变 graphene 氧化物,和这另外的 functionalization 的表面功能被显示了改变细胞的反应。因此,在这个工作,我们使用了没有标签的 graphene 氧化物。我们小心地用扫描 / 传播电子显微镜学追踪了三不同 nanoscale graphene 氧化物薄片尺寸分布的举起。举起在无差别的人的单核白血球房间(THP-1 ) 被调查并且区分了巨噬细胞房间。数据表演为举起的清楚的尺寸依赖,以便更大的 graphene 氧化物薄片(并且簇) 被房间更容易与更小的薄片相比收起。而且,举起被显示很快发生,在有 THP-1 房间的孵化的二 min 以内。数据与 nanoparticles 为细胞的孵化研究加亮关键需要,到作为某些相关性为短潜伏期被进行(例如,尺寸和集中) 与更长的潜伏期被失去。 | Rafael G. Mendes Angelo Mandarino Britta Koch Anne K. Meyer Alicja Bachmatiuk Cordula Hirsch Thomas Gemming Oliver G. Schmidt Zhongfan Liu Mark H. Rummeli | 2017 | Nano Research2017，10，6： | 1 |
| 5 | Pulse pressure variation does not reflect stroke volume variation in mechanically ventilated rats with lipopolysaccharide‐induced pneumonia显示文摘 | Thomas GV Cherpanath Lonneke Smeding Wim K Lagrand Alexander Hirsch Marcus J Schultz Johan AB Groeneveld | 2014 | Clin Exp Pharmacol Physiol2014，，1： | 1 |
| 6 | Occurrence of antibiotics in the aquatic environment显示文摘 | Roman Hirsch Thomas Temes Klaus Haberer | 1999 | The Science of The Total Environment1999，225，12： | 1 |
| 7 | Effects of altered phosphoenolpyruvate carboxylase activities on transgenic C3 plant Solanum tuberosum显示文摘 | Johanna Gehlen Ralph Panstruga Helga Smets Sabine Merkelbach Michael Kleines Petra Porsch Matthias Fladung Irmgard Becker Thomas Rademacher Rainer E. H?usler Heinz-Josef Hirsch | 1996 | Plant Molecular Biology1996，，5： | 1 |
| 8 | Oc- currence of antibiotics in the aquatic environment显示文摘 | Roman Hirsch Thomas Temes Klaus Haberer | 1999 | The Science of the Total Environment1999，225，13： | 1 |
| 9 | Occurrence of antibiotics in the aquatic environment显示文摘 | Roman Hirsch Thomas Ternes Klaus Haberer Karl-Ludwig Kratz | 1999 | Science of the Total Environment1999，，1： | 1 |
| 10 | Inhibition of calcification of glutaraldehyde pretreated porcine aortic valve cusps with sodium dodecyl sulfate:preincubation and controlled release studies显示文摘 | Hirsch D Drader J Thomas TJ | 1993 | J Biomed Mater Res1993，27，12： | 1 |
| 11 | Occurrence of antibiotics in the aquatic environment显示文摘 | Roman Hirsch Thomas Ternes Klaus Haberer Karl-Ludwig Kratz | 1999 | Science of the Total Environment1999，，1： | 1 |
| 12 | Occurrence of antibiotics in the aquatic environment显示文摘 | Roman Hirsch Thomas Ternes Klaus Haberer Karl-Ludwig Kratz | 1999 | Science of the Total Environment1999，，1： | 1 |
| 13 | Inhibition of calcification ofglutaraldehyde pretreated porcine aortic valve cusps with sodiumdodecylsulfate preincubation and controlled release studies显示文摘 | Hirsch D Drader J Thomas TJ | 1993 | JBiomed Mater Res1993，27，12： | 1 |
| 14 | Significance of Folate Receptor Alpha and Thymidylate Synthase Protein Expression in Patients with Non–Small-Cell Lung Cancer Treated with Pemetrexed显示文摘 | Daniel C. Christoph Bernadette Reyna Asuncion Biftu Hassan Cindy Tran Julia D. Maltzman Daniel J. O’Shannessy Murry W. Wynes Thomas C. Gauler Jeremias Wohlschlaeger Mathias Hoiczyk Martin Schuler Wilfried E. Eberhardt Fred R. Hirsch | 2013 | Journal of Thoracic Oncology2013，，1： | 1 |
| 15 | Large-scale generation of mature monocyte-derived dendritic cells for clinical application in cell factories?显示文摘 | Thomas G Berger Bernadette Feuerstein Erwin Strasser Ute Hirsch Doris Schreiner Gerold Schuler Beatrice Schuler-Thurner | 2002 | Journal of Immunological Methods2002，，2： | 1 |
| 16 | Insulin adsorption to polylefin infusion bottles and polyvinylchlorid administration sets显示文摘 | Hirsch J I Wood J H Thomas R B | 1981 | Am J Hosp Pharm1981，38，7： | 1 |
| 17 | Composite particles with magnetic properties,near-infrared excitation,and far-red emission for luminescence-based oxygen sensing显示文摘Oxygen sensing,magnetic,and upconversion luminescence properties are combined in multi-functional composite particles prepared herein by a simple mixing,baking,and grinding procedure.Upconverting nanocrystals are used as an excitation source and an oxygen indicator with far-red emission.The composite particles are excited with near infrared(NIR)laser light(980 nm).The visible upconversion emission is converted into an oxygen concentration-dependent far-red emission(<750 nm)using an inert mediator dye and a platinated benzoporphyrin dye.This concept combines the advantages of NIR excitation and far-red emissive indicator dyes,offering minimized auto-fluorescence and enhanced membrane permeability.Additional functionality is obtained by incorporating magnetic nanoparticles into the composite particles,which enables easy manipulation and separation of the particles by the application of an external magnetic field. | Elisabeth Scheucher Stefan Wilhelm Otto SWolfbeis Thomas Hirsch Torsten Mayr | 2015 | Microsystems & Nanoengineering2015，1，1： | 0 |
| 18 | Effect of gynecologic oncologist availability on ovarian cancer mortality显示文摘AIM: To determine the association between the distribution of gynecologic oncologist(GO) and populationbased ovarian cancer death rates. METHODS: Data on ovarian cancer incidence and mortality in the United States was supplemented with United States census data, and analyzed in relation to practicing GOs. GO locations were geocoded to link association between county variables and GO availability. Logistic regression was used to measure areas of high and low ovarian cancer mortality, adjusting for contextual variables. RESULTS: Practicing GOs were unevenly distributed in the United States, with the greatest numbers in metropolitan areas. Ovarian cancer incidence and death rates increased as distance to a practicing GO increased. A relatively small number(153) of counties within 24 miles of a GO had high ovarian cancer death rates compared to 577 counties located 50 or more miles away with high ovarian cancer death rates. Counties located 50 or more miles away from a GO practice had an almost 60% greater odds of high ovarian cancer mortality compared to those with closer practicing GOs(OR = 1.59, 95%CI: 1.18-2.15). CONCLUSION: The distribution of GOs across the United States appears to be significantly associated with ovarian cancer mortality. Efforts that facilitate outreach of GOs to certain populations may increase geographic access. | Sherri L Stewart Darryl Cooney Shawn Hirsch Lauren Westervelt Thomas B Richards Sun Hee Rim Cheryll C Thomas | 2014 | World Journal of Obstetrics and Gynecology2014，3，2： | 0 |
| 19 | Biliary drainage in inoperable malignant biliary distal obstruction: A systematic review and meta-analysis显示文摘BACKGROUND Endoscopic drainage remains the treatment of choice for unresectable or inoperable malignant distal biliary obstruction(MDBO).AIM To compare the safety and efficacy of plastic stent(PS)vs self-expanding metal stent(SEMS)placement for treatment of MDBO.METHODS This meta-analysis was developed according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines.A comprehensive search was performed in MEDLINE,Cochrane,Embase,Latin American and Caribbean Health Sciences Literature,and grey literature to identify randomized clinical trials(RCTs)comparing clinical success,adverse events,stent dysfunction rate,reintervention rate,duration of stent patency,and mean survival.Risk difference(RD)and mean difference(MD)were calculated and heterogeneity was assessed with I2 statistic.Subgroup analyses were performed by SEMS type.RESULTS Twelve RCTs were included in this study,totaling 1005 patients.There was no difference in clinical success(RD=-0.03,95%confidence interval[CI]:-0.01,0.07;I 2=0%),rate of adverse events(RD=-0.03,95%CI:-0.10,0.03;I2=57%),and mean patient survival(MD=-0.63,95%CI:-18.07,19.33;I2=54%)between SEMS vs PS placement.However,SEMS placement was associated with a lower rate of reintervention(RD=-0.34,95%CI:-0.46,-0.22;I2=57%)and longer duration of stent patency(MD=125.77 d,95%CI:77.5,174.01).Subgroup analyses revealed both covered and uncovered SEMS improved stent patency compared to PS(RD=152.25,95%CI:37.42,267.07;I2=98%and RD=101.5,95%CI:38.91,164.09;I2=98%;respectively).Stent dysfunction was higher in the covered SEMS group(RD=-0.21,95%CI:-0.32,-0.1;I²=205%),with no difference in the uncovered SEMS group(RD=-0.08,95%CI:-0.56,0.39;I²=87%).CONCLUSION While both stent types possessed a similar clinical success rate,complication rate,and patient-associated mean survival for treatment of MDBO,SEMS were associated with a longer duration of stent patency compared to PS. | Maria Vitória Cury Vieira Scatimburgo Igor Braga Ribeiro Diogo Turiani Hourneaux de Moura Vitor Massaro Takamatsu Sagae Bruno Salomão Hirsch Mateus Bond Boghossian Thomas R McCarty Marcos EduardoLera dos Santos Tomazo Antonio Prince Franzini Wanderley Marques Bernardo Eduardo GuimarãesHourneaux de Moura | 2021 | World Journal of Gastrointestinal Surgery2021，13，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员