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| 1 | Attractive but Toxic: Emerging Roles of Glycosidically Bound Volatiles and Glycosyltransferases Involved in Their Formation显示文摘 | Chuankui Song Katja Hartl Kate McGraphery Thomas Hoffmann Wilfried Schwab | 2018 | Molecular Plant2018，11，10： | 16 |
| 2 | The Strawberry Fruit Fra a Allergen Functions in Flavonoid Biosynthesis显示文摘1 变应原是的草莓兄弟主要桦树花粉变应原的一个相当或相同的事物赌了 v 1。当变异的遗传型的白水果,被知道被过敏症影响的个人容忍,缺乏它时,它被 Fragaria x ananassa 的红成熟水果综合。Proteomic 分析显示出 1 是的那个兄弟在与 anthocyanin 颜料小径的酶一起的容忍的白水果的遗传型下面调整。在这研究,我们报导三个兄弟的空间、时间的表示一编码不同 isoforms 的基因,和兄弟的短暂调停 RNAi 的 silencing 一在有 ihpRNA 的红水果的栽培变种 Elsanta 的草莓水果的基因构造。作为兄弟的减少的层次的后果 mRNAs,水果被获得那生产了 anthocyanins 和在上游的代谢物的显著地减少的层次。这效果与本氨基丙酸氨 lyase (FaPAL ) 的平行下面规定一致,到 chalcone synthase (FaCHS ) 的更小的程度,抄本层次也在这些水果发现。在 F 的自然地发生的白水果的遗传型。chiloensis 和 F。vesca,一个抄本铺平的兄弟比红水果的变化的那些高,可能在这些变异的遗传型补偿 FaPAL 和 FaCHS 的低表示层次。结果表明那个兄弟表情直接被连接到 flavonoid 生合成和表演变应原有的兄弟在在草莓的颜料形成的必要生物功能水果。 | Cristina Munoz Thomas Hoffmann Nieves Medina Escobar Felix Ludemann Miguel A. Botella Victoriano Valpuesta Wilfried Schwab | 2010 | Molecular Plant2010，3，1： | 6 |
| 3 | 产生埃博霉素的纤维堆囊菌的分子筛选显示文摘为寻找潜在的产生埃博霉素(epothilone)的纤维堆囊菌(Sorangium cellulosum),以埃博霉素生物合成基因簇中的epoA,epoC和epoK基因为探针,分别对60株不同土壤样品来源的纤维堆囊菌的DNA样品进行PCR筛选.筛选结果得到了7株阳性菌株,进一步对其进行发酵和粗提物的HPLC-MS分析,检测结果显示3株菌XMU-Nc-03,XMU-So-64和XMU-So-112能产生埃博霉素B,其中XMU-So-112的产量最高.本实验在筛选产埃博霉素活性菌株的同时,还建立了一个快速可靠的发现埃博霉素产生菌的方法. | 欧一新 Thomas Hoffmann 任闪闪 常宁宁 吴莹莹 苏文金 Rolf Müller 钱晓鸣 | 2012 | 厦门大学学报(自然科学版)2012，51，3： | 3 |
| 4 | A LIM Domain Protein from Tobacco Involved in Actin-Bundling and Histone Gene Transcription显示文摘从植物(秘鲁利玛机场之代号) 的二秘鲁利玛机场之代号包含域的蛋白质典型地展出双 cytoplasmicnuclear 分布,建议除了他们在肌动朊细胞骨架组织的以前描述的角色,他们参予原子过程。用针对识别绑种 histone 基因倡导者的因素的一幅西南的基于污点的屏幕,我们孤立包含烟草秘鲁利玛机场之代号蛋白质 WLIM2 (NtWLIM2 ) 的积极克隆 cDNA。用两块草地荧光灯蛋白质(GFP ) 基于熔化、基于免疫学的策略,我们提供 NtWLIM2 本地化到肌动朊细胞骨架,原子核,和核的清楚的证据。有趣地,由 latrunculin B 的肌动朊细胞骨架的混乱显著地增加 NtWLIM2 原子部分,指出可能的新奇 cytoskeletalnuclear 串音。生物化学并且电子显微镜学实验揭示 NtWLIM2 的能力直接把后者绑在肌动朊细丝并且到交叉连接进厚肌动朊捆。NtWLIM2 明确地绑在 Arabidopsis histone H4A748 基因倡导者的保存 octameric cis 元素(10 月) 并且这绑定大部分依靠两个秘鲁利玛机场之代号领域的 Electrophoretic 活动性移动试金表演。重要地,在 Arabidopsis 和烟草原物进行的基于记者的实验证实 NtWLIM2 的能力绑在并且在实时房间激活 H4A748 基因倡导者。表示研究在烟草 BY-2 房间增长和房间周期前进期间显示 NtWLIM2 mRNA 和 NtWLIM2 蛋白质的组成的存在,建议在基础 histone 基因表示的激活的 NtWLIM2 的一个角色。有趣地,两个都生活房间并且在 vitro 数据支持 NtWLIM2 di/oligomerization。我们建议 NtWLIM2 作为稳定肌动朊的蛋白质工作,它在改变的细胞骨架之上,梭到原子核以便修改基因表示。 | Danièle Moes Sabrina Gatti CEline Hoffmann Monika Dieterle Flora Moreau Katrin Neumann Marc Schumacher Marc Diederich Erwin Grill Wen-Hui Shen André Steinmetz Cldment Thomas | 2013 | Molecular Plant2013，6，2： | 2 |
| 5 | Changes of Coronary Calcification After Kidney Transplantation显示文摘 | Elisabeth Oschatz Thomas Benesch Katharina Kodras Udo Hoffmann Martin Haas | 2006 | American Journal of Kidney Diseases2006，，2： | 2 |
| 6 | Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods显示文摘Neutralizing antibodies targeting the receptor-binding domain(RBD)of the SARS-CoV-2 spike(S)block severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)entry into cells via surface-expressed angiotensin-converting enzyme 2(ACE2).We used a surrogate virus neutralization test(sVNT)and SARS-CoV-2 S protein-pseudotyped vesicular stomatitis virus(VSV)vector-based neutralization assay(pVNT)to assess the degree to which serum antibodies from coronavirus disease 2019(COVID-19)convalescent patients interfere with the binding of SARS-CoV-2 S to ACE2.Both tests revealed neutralizing anti-SARS-CoV-2 S antibodies in the sera of ~90% of mildly and 100% of severely affected COVID-19 convalescent patients.Importantly,sVNT and pVNT results correlated strongly with each other and to the levels of anti-SARS-CoV-2 S1 IgG and IgA antibodies.Moreover,levels of neutralizing antibodies correlated with the duration and severity of clinical symptoms but not with patient age.Compared to pVNT,sVNT is less sophisticated and does not require any biosafety labs.Since this assay is also much faster and cheaper,sVNT will not only be important for evaluating the prevalence of neutralizing antibodies in a population but also for identifying promising plasma donors for successful passive antibody therapy. | Berislav Bosnjak Saskia Catherina Stein Stefanie Willenzon Anne Katrin Cordes Wolfram Puppe Gunter Bernhardt Inga Ravens Christiane Ritter Christian R.Schultze-Florey Nina Godecke Jorg Martens Hannah Kleine-Weber Markus Hoffmann Anne Cossmann Mustafa Yilmaz Isabelle Pink Marius M.Hoeper Georg M.N.Behrens Stefan Pohlm ann Rainer Blasczyk Thomas F.Schulz Reinhold Forster | 2021 | Cellular & Molecular Immunology2021，18，4： | 2 |
| 7 | Cardiac Magnetic Resonance With T2-Weighted Imaging Improves Detection of Patients With Acute Coronary Syndrome in the Emergency Department显示文摘 | Ricardo C. Cury Khalid Shash John T. Nagurney Guido Rosito Michael D. Shapiro Cesar H. Nomura Suhny Abbara Fabian Bamberg Maros Ferencik Ehud J. Schmidt David F. Brown Udo Hoffmann Thomas J. Brady | 2008 | Circulation2008，，8： | 1 |
| 8 | Expression of metallothionein Ⅱ in intestinal metaplasia,dysplasia,and gastric cancer显示文摘 | Matthias P A Ebert Thomas Günther Juliane Hoffmann | 2000 | Cancer Research2000，60，： | 1 |
| 9 | Thin films in pho- tovoltaics: Technologies and perspectives 显示文摘 | Winfried Hoffmann Thomas Pellkofer | 2012 | Thin Solid Films2012，520，： | 1 |
| 10 | CRP and CD14 polymorphisms correlate with coronary plaque volume in patients with coronary artery disease – IVUS substudy of the ENCORE trials显示文摘 | Matthias Hermann Dieter Fischer Michael M. Hoffmann Theo Gasser Kurt Quitzau Thomas Meinertz Thomas Münzel Thomas F. Lüscher | 2011 | Atherosclerosis2011，，1： | 1 |
| 11 | Click Che- mistry on Surfaces : 1,3-Dipolar Cycloaddition Reactions of Azide-terminated Monolayers on Silica 显示文摘 | THOMAS Lummerstorfer HELMUTH Hoffmann | 2004 | The Journal of Physical Chemistry B2004，108，13： | 1 |
| 12 | Surgical Management of Pulmonary Metastases from Colorectal Cancer in 153 Patients显示文摘 | Süleyman Yedibela Peter Klein Karsta Feuchter Martin Hoffmann Thomas Meyer Thomas Papadopoulos Jonas G?hl Werner Hohenberger | 2006 | Annals of Surgical Oncology2006，，11： | 1 |
| 13 | Click chemistry on surfaces:1,3-dipolar cycloaddition reactions of azide-terminated monolayers on silica显示文摘 | Thomas Lummerstorfer Helmuth Hoffmann | 2004 | Journal of Physical Chemistry B2004，108，13： | 1 |
| 14 | Mass flow during unloading of agricultural bulk materials from silos depending on particle form, flow properties and geometry of the discharge opening显示文摘 | Jochen Mellmann Thomas Hoffmann Christian Fürll | 2014 | Powder Technology2014，，： | 1 |
| 15 | Nodal Involvement at the Time of Pulmonary Metastasectomy: Experiences in 245 Patients显示文摘 | Joachim Pfannschmidt Joachim Klode Thomas Muley Hendrik Dienemann Hans Hoffmann | 2006 | The Annals of Thoracic Surgery2006，，2： | 1 |
| 16 | Live cell imaging reveals actin-cytoskeleton-induced self-association of the actin-bundling protein WLIM1显示文摘 | Hoffmann C Moes D Dieterle M Neumann K Moreau F Tavares F A Dumas D Stein- metz A Thomas C | 2014 | Journal of Cell Science2014，127，3： | 1 |
| 17 | Prognostic factors and survival after complete resection of pulmonary metastases from colorectal carcinoma: Experiences in 167 patients显示文摘 | Joachim Pfannschmidt Thomas Muley Hans Hoffmann Hendrik Dienemann | 2003 | The Journal of Thoracic and Cardiovascular Surgery2003，，3： | 1 |
| 18 | Sleeve Pneumonectomy for Central Non-Small Cell Lung Cancer: Indications, Complications, and Survival显示文摘 | Florian Eichhorn Konstantina Storz Hans Hoffmann Thomas Muley Hendrik Dienemann | 2013 | The Annals of Thoracic Surgery2013，，1： | 1 |
| 19 | Dual and opposing roles of EIN3 reveal a generation conflict during seed growth显示文摘Seed size critically affects grain yield of crops and hence represents a key breeding target.The develop-ment of embryo-nourishing endosperm is a key driver of seed expansion.We here report unexpected dual roles of the transcription factor EIN3 in regulating seed size.These EIN3 functions have remained largely undiscovered because they oppose each other.Capitalizing on the analysis of multiple ethylene biosynthesis mutants,we demonstrate that EIN3 represses endosperm and seed development in a pathway regulated by ethylene.We,in addition,provide evidence that EIN3-mediated synergid nucleus disintegration promotes endosperm expansion.Interestingly,synergid nucleus disintegration is not affected in various ethylene biosynthesis mutants,suggesting that this promoting function of EIN3 is inde-pendent of ethylene.Whereas the growth-inhibitory ethylene-dependent EIN3 action appears to be encoded by sporophytic tissue,the growth-promoting role of EIN3 is induced by fertilization,revealing a generation conflict that converges toward the key signaling component EIN3. | Juliane Heydlauff Isil Erbasol Serbes Dieu Vo Yanbo Mao Sonja Gieseking Thomas Nakel Theresa Harten Ronny Völz Anja Hoffmann Rita GroΒ-Hardt | 2022 | Molecular Plant2022，15，2： | 1 |
| 20 | Virtual world experimentation: An exploratory study 显示文摘 | Thomas Chesney Swee-Hoon Chuah Robert Hoffmann | 2009 | Journal of Economic Behavior & Organization2009，，10： | 1 |
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