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105篇 您的检索式:作者名="Watkins PA"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2A very long-chain acyl- coa synthetase--deficient mouse and its relevane to X-linked adrenolenkodystrophy显示文摘Heinzer Ak Watkins PA Jyh-Feng L et ai 2003Hum Mol Genet2003,12,10:1
3Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance显示文摘Lau WC Gurbel PA Watkins PB 2004Circulation2004,109,:1
4Laparoscopic hepatic resection using saline-enhanced electrocautery permits short hospital stays显示文摘Learn PA Bowers SP Watkins KT 2006J Gastrointest Surg2006,10,3:1
5Contribution of he- patic cytochrome P450 3A4 metabolic activity to the phe- nomenon of clopidogrel resistance显示文摘Lau WC Gurbel PA Watkins PB 2004Circulation2004,109,2:1
6Contribution of hepatic cytochrome p450 3A4 metabolic activity to the phenomenon of clopidogrel resistance显示文摘Lau WC Gurbel PA Watkins PB 2004Circulation2004,109,2:1
7Contribution of he- patic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance 显示文摘Lau WC Gurbel PA Watkins PB 2004Circulation2004,109,2:1
8Contribution of hepatic cy- tochrome P450 3A4 metabolic activity to the phenomenon of clopi- dog relresistance 显示文摘Lau WC Gurbel PA Watkins PB 2004Circulation2004,109,2:1
9Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance 显示文摘Lau WC Gurbel PA Watkins PB 2004Circulation2004,109,:1
10Contribution of hepatic cytochrome P 450 3A4 metabolic activity to the phenomenon of clopidogrel resistance显示文摘Lau WC Gurbel PA Watkins PB 2004Circulation2004,109,2:1
11Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance 显示文摘Lau WC Gurbel PA Watkins PB 2004Circulation2004,109,2:1
12The future for treatment by bone marrow transplantation for adrenoleukodystrophy,metachromatic leukodystrophy,globoid cell leukodystrophy and Hurler syndrome显示文摘Krivit W Lockman LA Watkins PA 0,,04:1
13Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance 显示文摘Lau WC Gurbel PA Watkins PB 2004Circulation2004,109,2:1
14Research experience in an undergraduate physical therapy program显示文摘Cerasoli PA Watkins MP 1977Phys Ther1977,57,1:1
15Proliferating cell nuclear antigen immulocalization in paraffin in section : an index of cell proliferation with evidence deregulated expression in some neoplasms显示文摘Hall PA Levison DA Woods AL Yucc Kellock DB Watkins JA 1990J Pathol1990,162,4:1
16The evolution of end masa dacry Yst orhinostomy Survey of oph thanomology 显示文摘Watkins Lm Jan Faza P Rubin PA 200348 ( 1 ) :73 -842003,48,1:1
17Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance 显示文摘Lau WC Gurbel PA Watkins PB 2004Circulation2004,109,2:1
18Platelet reactivity in coronary ostial blood:a reflection of the thrombotic state accompanying plaque rupture and of the adequacy of anti-thrombotic therapy显示文摘Kabbani SS Watkins MW Holoch PA 2001J Thromb Thrombolysis2001,12,:1
19Contribution of hepatic cytochrome p450 3A4 metabolic activity to the phenomenon of clopidogrel resistance显示文摘Lau WC Gurbel PA Watkins PB 2004Circulation2004,109,:1
20Contribution of hepatic cytochrome P4503A4metabolic activity to the phenomenon of clopidogrel resistance显示文摘LauW C Gurbel PA Watkins PB 2004Circulation2004,109,2:1
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