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| 1 | Mesenchymal stem cells: a new strategy for immunosuppression and tissue repair显示文摘间充质的干细胞(MSC ) 为治疗各种各样的疾病有大潜力,特别那些与织物有关损坏包含有免疫力的反应。各种各样的研究证明了 MSC 在 vitro 并且在 vivo 是强烈抑制免疫力的。我们的最近的研究证明了那未刺激的 MSC 确实不能免疫力的抑制;他们与 TNF- 伪, IL-1 伪或 IL-1 尾与激活的淋巴细胞的上层清液,或与 IFN- 纬的联合在刺激之上变得 potently 抑制免疫力。这观察表明在某些情形下面,煽动性的 cytokines 能实际上变得抑制免疫力。我们证明在调停 MSC 的免疫力的抑制的机制有一个种类变化:由告知 cytokine 的老鼠 MSC 的免疫力的抑制被氮的氧化物调停(没有) 而由告知 cytokine 的人的 MSC 的免疫力的抑制通过 indoleamine 被执行 2, 3-dioxygenase (伊多语) 。在有煽动性的 cytokines 的刺激之上,另外,老鼠和人的 MSC 分泌几白血球 chemokines 显然服务与 MSC 吸引有免疫力的房间进最近,在哪儿不或伊多语被预言很活跃。因此,由煽动性的刺激 cytokine 的 MSC 的免疫力的抑制经由 chemokines 的一致行动发生并且免疫者禁止没有或伊多语由 MSC 生产了。因此,我们的结果在对待有免疫力的回答导致的织物损害关于调停 MSC 的免疫力的抑制并且为 MSC 的更好的申请的机制提供新奇信息。 | Yufang Shi Gangzheng Hu Juanjuan Su Wenzhao Li Qing Chen Peishun Shou Chunliang Xu Xiaodong Chen Yin Huang Zhexin Zhu Xin Huang Xiaoyan Han Ningxia Xie Guangwen Ren | 2010 | Cell Research2010，20，5： | 72 |
| 2 | Clinical features and treatment status of hemifacial spasm in China显示文摘 | Wang Lin Hu Xingyue Dong Hongjuan Wang Wenzhao Huang Yue Jin Lingjing Luo Yumin Zhang Weixi Lian Yajun Liang Zhanhua Shang Huifang Feng Yabo wu Yiwen Chen Jun Luo Weifeng Wan Xinhua | 2014 | Chinese Medical Journal2014，，5： | 20 |
| 3 | Clinical efficacy of 0.1% pranoprofen in treatment of dry eye patients:a multicenter, randomized, controlled clinical trial显示文摘 | Chen Jingyao Dong Fei Chen Wei Sun Xuguang Deng Yingping Hong Jing Zhang Mingchang Yang Wenzhao Liu Zuguo Xie Lixin | 2014 | Chinese Medical Journal2014，，13： | 18 |
| 4 | Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology显示文摘Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously.Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the China Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation. | Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu Jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan Wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong Wu | 2019 | Cancer Biology & Medicine2019，16，1： | 14 |
| 5 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 6 | High nitrogen application rate and planting density reduce wheat grain yield by reducing filling rate of inferior grain in middle spikelets显示文摘Excessive use of nitrogen fertilizer and high planting density reduce grain weight in wheat.However,the effects of high nitrogen and planting density on the filling of grain located in different positions of the wheat spikelet are unknown.A two-year field experiment was conducted to investigate this question and the underlying mechanisms with respect to hormone and carbohydrate activity.Both high nitrogen application and planting density significantly increased spike density,while reducing kernel number per spike and 1000-kernel weight.However,the effects of high nitrogen and high plant density on kernel number per spike and 1000-kernel weight were different.The inhibitory effect of high nitrogen application and high planting density on kernel number per spike was achieved mainly by a reduction in kernel number per spikelet in the top and bottom spikelets.However,the decrease in 1000-kernel weight was contributed mainly by the reduced weight of grain in the middle spikelets.The grain-filling rate of inferior grain in the middle spikelets was significantly decreased under high nitrogen input and high planting density conditions,particularly during the early and middle grain-filling periods,leading to the suppression of grain filling and consequent decrease in grain weight.This effect resulted mainly from inhibited sucrose transport to and starch accumulation in inferior grain in the middle spikelets via reduction of the abscisic acid/ethylene ratio.This mechanism may explain how high nitrogen application and high planting density inhibit the grain filling of inferior wheat grain. | Yang Liu Yuncheng Liao Wenzhao Liu | 2021 | The Crop Journal2021，9，2： | 9 |
| 7 | Soil temperature and moisture sensitivities of soil CO_2 efflux before and after tillage in a wheat field of Loess Plateau,China显示文摘As a conventional farming practice,tillage has lasted for thousands of years in Loess Plateau,China.Although recent studies show that tillage is a prominent culprit to soil carbon loss in croplands,few studies have investigated the influences of tillage on the responses of soil CO2 efflux(SCE) to soil temperature and moisture.Using a multi-channel automated CO2 efflux chamber system,we measured SCE in situ continuously before and after the conventional tillage in a rain fed wheat field of Loess Plateau,China.The changes in soil temperature and moisture sensitivities of SCE,denoted by the Q10 value and linear regression slope respectively,were compared in the same range of soil temperature and moisture before and after the tillage.The results showed that,after the tillage,SCE increased by 1.2-2.2 times;the soil temperature sensitivity increased by 36.1%-37.5%;and the soil moisture sensitivity increased by 140%-166%.Thus,the tillage-induced increase in SCE might partially be attributed to the increases in temperature and moisture sensitivity of SCE. | Hongxing Zhang Xiaoke Wang Zongwei Feng Junzhu Pang Fei Lu Zhiyun Ouyang Hua Zheng Wenzhao Liu Dafeng Hui | 2011 | Journal of Environmental Sciences2011，23，1： | 7 |
| 8 | Neomycin biosynthesis is regulated positively by AfsA-g and NeoR in Streptomyces fradiae CGMCC 4.7387显示文摘Neomycins are a group of aminoglycoside antibiotics with both clinical and agricultural applications.To elucidate the regulatory mechanism of neomycin biosynthesis,we completed draft genome sequencing of a neomycin producer Streptomyces fradiae CGMCC 4.7387 from marine sediments,and the neomycin biosynthesis gene cluster was identified.Inactivation of the afsA-g gene encoding a γ-butyrolactone(GBL) synthase in S.fradiae CGMCC 4.7387 resulted in a significant decrease of neomycin production.Quantitative RT-PCR analysis revealed that the transcriptional level of neoR and the aphA-neoGH operon were reduced in the afsA-g::aac(3)Ⅳ mutant.Interestingly,a conserved binding site of AdpA,a key activator in the GBL regulatory cascade,was discovered upstream of neoR,a putative regulatory gene encoding a protein with an ATPase domain and a tetratricopeptide repeat domain.When neoR was inactivated,the neomycin production was reduced about 40%in comparison with the WT strain.Quantitative RT-PCR analysis revealed that the transcriptional levels of genes in the aphA-neoGH operon were reduced clearly in the neoR::aac(3)Ⅳ mutant.Finally,the titers of neomycin were improved considerably by overexpression of qfsA-gand neoR in S.fradiae CGMCC 4.7387. | Xiangxi Meng Wenzhao Wang Zhoujie Xie Pengwei Li Yue Li Zhengyan Guo Yingjian Lu Jie Yang Kaile Guan Zhaoxin Lu Huarong Tan Yihua Chen | 2017 | Science China(Life Sciences)2017，60，9： | 7 |
| 9 | 狄氏副拟杆菌通过产生琥珀酸和次级胆汁酸减轻肥胖和代谢功能障碍显示文摘文章简介狄氏副拟杆菌是人体核心菌群之一,相关性分析表明其含量与肥胖、非酒精性脂肪肝、糖尿病等疾病状态呈显著负相关,提示其可能在糖脂代谢方面发挥正向调节作用。本研究发现狄氏副拟杆菌可以显著改善高脂饮食诱导肥胖(DIO)小鼠及ob/ob肥胖模型小鼠的肥胖、胰岛素抵抗、脂代谢紊乱及非酒精性脂肪肝症状。 | 汪锴 廖明芳 周楠 Li Bao Ke Ma Zhongyong Zheng Yujing Wang Chang Liu Wenzhao Wang Jun Wang 刘双江 刘宏伟 | 2020 | 科学新闻2020，，2： | 6 |
| 10 | Studies on Factors Influencing Hydrodynamic Characteristics of Plates Used in Artificial Reefs显示文摘As a simplified model of artificial reefs, a series of plate models punched with square or circular openings are designed to investigate the effects of openings on the hydrodynamic characteristics of artificial reefs. The models are grouped by various opening numbers and opening-area ratios. They are physically tested in a water flume or used in the numerical simulation to obtain the drag force in the uniform flow with different speeds. The simulation results are found in good agreement with the experimental measurements. By the non-dimensional analysis, the drag coefficient specified to each model is achieved and the effects of openings are examined. It is found that the key factor affecting the drag coefficient is the open-area ratio. Generally, the drag coefficient is a linear function of the open area ratio with a minus slope. The empirical formulae for the square and circular openings respectively are deduced by means of the multiple regression analysis based on the measured and numerical data. They will be good references for the design of new artificial reefs. As a result of numerical simulation, the vorticity contours and pressure distribution are also presented in this work to better understand the hydrodynamic characteristics of different models. | TANG Yanli YANG Wenzhao SUN Liyuan ZHAO Fenfang LONG Xiangyu WANG Gang | 2019 | Journal of Ocean University of China2019，18，1： | 6 |
| 11 | Polyoxometalates-engineered hydrogen generation rate and durability of Pt/CNT catalysts from ammonia borane显示文摘Heterogeneously catalyzed hydrolytic dehydrogenation of ammonia borane is a remarkable structure sensitive reaction. In this work, a strategy by using polyoxometalates(POMs) as the ligands is proposed to engineer the surface and electronic properties of Pt/CNT catalysts toward the enhanced hydrogen generation rate and durability. Three kinds of POMs, i.e., silicotungstic acid(STA), phosphotungstic acid(PTA)and molybdophosphoric acid(PMA), are comparatively studied, among which the STA shows positive effects on the catalytic activity and durability. A catalyst structure-performance relationship is established by a combination of kinetic and isotopic analyses with multiple characterization techniques, such as HAADF-STEM, EDS, Raman spectroscopy and XPS. It is shown that the STA compared to the other two POMs can increase the Pt binding energy and thus promote the reaction. The insights demonstrated here could open a new avenue for boosting the reaction by employing the POMs as the ligands to engineer the catalyst electronic properties. | Wenzhao Fu Chen Han Dali Li Wenyao Chen Jian Ji Gang Qian Weikang Yuan Xuezhi Duan Xinggui Zhou | 2020 | Journal of Energy Chemistry2020，29，2： | 5 |
| 12 | Relationship of gelatinases-tight junction proteins and blood-brain barrier permeability in the early stage of cerebral ischemia and reperfusion显示文摘Gelatinases matrix metalloproteinase-2 and matrix metalloproteinase-9 have been shown to mediate claudin-5 and occludin degradation, and play an important regulatory role in blood-brain barrier permeability. This study established a rat model of 1.5-hour middle cerebral artery occlusion with reperfusion. Protein expression levels of claudin-5 and occludin gradually decreased in the early stage of reperfusion, which corresponded to the increase of the gelatinolytic activity of matrix metalloproteinase-2 and matrix metalloproteinase-9. In addition, rats that received treatment with matrix metalloproteinase inhibitor N-[(2R)-2-(hydroxamidocarbonylmethyl)-4-methylpenthanoyl]-L- tryptophan methylamide (GM6001) showed a significant reduction in Evans blue leakage and an inhibition of claudin-5 and occludin protein degradation in striatal tissue. These data indicate that matrix metalloproteinase-2 and matrix metalloproteinase-9-mediated claudin-5 and occludin degradation is an important reason for blood-brain barrier leakage in the early stage of reperfusion. The leakage of the blood-brain barrier was present due to gelatinases-mediated degradation of claudin-5 and occludin proteins. We hypothesized that the timely closure of the structural component of the blood-brain barrier (tight junction proteins) is of importance. | Haolin Xin Wenzhao Liang Jing Mang Lina Lin Na Guo Feng Zhang Zhongxin Xu | 2012 | Neural Regeneration Research2012，7，31： | 4 |
| 13 | Basic characteristics and evaluation of shale oil reservoirs显示文摘Shale oil refers to liquid hydrocarbons existing in free,dissolved or adsorbed states in the effective source rock of mudstones or shales,where some residual oil is retained after hydrocarbon generation and expulsion from the mudstones or shales.Basically shale oil experiences no migration or only undergoes some primary,short-distance migration within the source rocks.So far,there is no consensus on the exact definition of shale oil in China.Researches on the reservoir-controlling factors and evaluation elements are also far from sufficient.In this study,shale oil reservoirs are defined as mudstones or shales excluding the interbedded or adjacent layers of coarser siliciclastic or chemical-biogenic lithofacies(e.g.siltstone,carbonate,salt or chert layers)in the source rocks.According to different reservoiring mechanisms,shale oil reservoirs are classified into“fracture type”and“matrix type”.The general features of shale oil reservoirs include:rich in organic matters,dominated by Type I and II_(1) kerogen(with Ro=0.6%-1.2%and total organic content(TOC)>2.0%),complex mineral compositions and laminated structures,tight storage space,low porosity and ultra-low permeability,and as well as the requirement for reservoir fracturing.This paper emphasizes the critical role of organic matter in the formation and evaluation of shale oil reservoirs,and its critical control on the oil generation potential and storage capacity of shale,which eventually determine the oil content and productivity of shale oil reservoirs.Besides,a set of reservoir evaluation criteria is also put forward with a focus on the TOC content,in which the threshold values of TOC are set to be 2%and 4%,and a variety of indicators are taken into account including the type and maturity of organic matter,the thickness of organic-rich shale,mineral compositions and rock types,porosity and permeability,and fracturing ability.The evaluation criteria divide shale oil reservoirs into three grades,i.e.,target reservoir,favorable reservoir and invalid reservoir. | Zaixing Jiang Wenzhao Zhang Chao Liang Yongshi Wang Huimin Liu Xiang Chen | 2016 | Petroleum Research2016，1，2： | 4 |
| 14 | Soil erosion assessment by RUSLE with improved P factor and its validation:Case study on mountainous and hilly areas of Hubei Province,China显示文摘The Revised Universal Soil Loss Equation(RUSLE)is widely used to estimate regional soil erosion.However,quantitative impacts of soil and water conservation(SWC)measures on conservation practice factor(P)of the RUSLE remain largely unclear,especially for the mountainous and hilly areas.In this study,we improved the RUSLE by considering quantitative impacts of different SWC measures on the P factor value.The improved RUSLE was validated against the long-term(2000-2015)soil erosion monitoring data obtained from 96 runoff plots(15—35°)in mountainous and hilly areas of Hubei Province,China;the result presented a high accuracy with the determination coefficient of 0.89.Based on the erosion monitoring data of 2018 and 2019,the Root Mean Square Error of the result by the improved RUSLE was 28.0%smaller than that by the original RUSLE with decrement of 19.6%—24.0%in the average P factor values,indicating that the soil erosion modelling accuracy was significantly enhanced by the improved RUSLE.Relatively low P factor values appeared for farmlands with tillage measures(P<0.53),grasslands with engineering measures(P<0.23),woodlands with biological measures(P<0.28),and other land use types with biological measures(P<0.51).The soil erosion modulus showed a downward trend with the corresponding values of 1681.21,1673.14,1594.70,1482.40 and 1437.50 t km^(-2)a-1 in 2000,2005,2010,2015 and 2019,respectively.The applicability of the improved RUSLE was verified by the measurements in typical mountainous and hilly areas of Hubei Province,China,and arrangements of SWC measures of this area were proposed. | Pei Tian Zhanliang Zhu Qimeng Yue Yi He Zhaoyi Zhang Fanghua Hao Wenzhao Guo Lin Chen Muxing Liu | 2021 | International Soil and Water Conservation Research2021，9，3： | 4 |
| 15 | Relationships Between Community Structure and Environmental Factors in Xixiakou Artificial Reef Area显示文摘The construction of artificial reefs has unparallelly developed for a few decades in China.Artificial reefs can be used to manage and conserve commercially exploited fish and crustacea.However,their suitability as ecological niche is poorly characterized.Therefore,in this study,we detected the seasonal variation of community biodiversity and the corresponding driving environmental factors.We also explored the relationships between dominant species and environmental factors to identify appropriate ecological niche areas.Different statistical analysis methods were used to assess species distribution within an artificial reef area in Xixiakou during nine sampling events in four seasons between 2017 and 2018.Non-metric multidimensional scaling(NMDS)and cluster analysis results indicated that the components of community can be divided into two clusters.Complexity of community,which is exhibited by species number,biodiversity,and catch per unit effort(CPUE),was significantly higher in summer than in other seasons.Generalized additive model(GAMs)results revealed the significant effects of temperature and chlorophyll a on the community structure.Sebastes schlegelii,Hexagrammos otakii,Conger myriaster and Charybdis japonica were the dominant species in four seasons.GAMs results indicated that temperature,dissolved oxygen(DO),pH and chlorophyll a affect the CPUE of dominant species significantly.The distinct suitable ecological niche for each dominant species was found in this study.For example,Charybdis japonica preferred to live in the area with 20.7–22.1℃,dissolved oxygen 7.07–7.15 mg L−1 and salinity 31.8–31.9.The results of this study are beneficial to resource conservation and fishery management. | YU Haolin YANG Wenzhao LIU Changdong TANG Yanli SONG Xiefa FANG Guangjie | 2020 | Journal of Ocean University of China2020，19，4： | 4 |
| 16 | Inverse Optimal Control for Speed-varying Path Following of Marine Vessels with Actuator Dynamics显示文摘A controller which is locally optimal near the origin and globally inverse optimal for the nonlinear system is proposed for path following of over actuated marine crafts with actuator dynamics. The motivation is the existence of undesired signals sent to the actuators, which can result in bad behavior in path following. To attenuate the oscillation of the control signal and obtain smooth thrust outputs, the actuator dynamics are added into the ship maneuvering model. Instead of modifying the Line-of-Sight (LOS) guidance law, this proposed controller can easily adjust the vessel speed to minimize the large cross-track error caused by the high vessel speed when it is turning. Numerical simulations demonstrate the validity of this proposed controller. | Yang Qu Haixiang Xu Wenzhao Yu Hui Feng Xin Han | 2017 | Journal of Marine Science and Application2017，16，2： | 3 |
| 17 | Classification of Hydrocarbon-Bearing Fine-Grained Sedimentary Rocks显示文摘Fine-grained sedimentary rocks are defined as rocks which mainly compose of fine grains(<62.5 μm). The detailed studies on these rocks have revealed the need of a more unified, comprehensive and inclusive classification. The study focuses on fine-grained rocks has turned from the differences of inorganic mineral components to the significance of organic matter and microorganisms. The proposed classification is based on mineral composition, and it is noted that organic matters have been taken as a very important parameter in this classification scheme. Thus, four parameters, the TOC content, silica(quartz plus feldspars), clay minerals and carbonate minerals, are considered to divide the fine-grained sedimentary rocks into eight categories, and the further classification within every category is refined depending on subordinate mineral composition. The nomenclature consists of a root name preceded by a primary adjective. The root names reflect mineral constituent of the rock, including low organic(TOC<2%), middle organic(2%4%) claystone, siliceous mudstone, limestone, and mixed mudstone. Primary adjectives convey structure and organic content information, including massive or limanited. The lithofacies are closely related to the reservoir storage space, porosity, permeability, hydrocarbon potential and shale oil/gas sweet spot, and are the key factor for the shale oil and gas exploration. The classification helps to systematically and practicably describe variability within fine-grained sedimentary rocks, what's more, it helps to guide the hydrocarbon exploration. | Zaixing Jiang Hongjie Duan Chao Liang Jing Wu Wenzhao Zhang Jianguo Zhang | 2017 | Journal of Earth Science2017，28，6： | 3 |
| 18 | Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma显示文摘 | Jin Hou Li Lin Weiping Zhou Zhengxin Wang Guoshan Ding Qiongzhu Dong Lunxiu Qin Xiaobing Wu Yuanyuan Zheng Yun Yang Wei Tian Qian Zhang Chunmei Wang Qinghua Zhang Shi-Mei Zhuang Limin Zheng Anmin Liang Wenzhao Tao Xuetao Cao | 2011 | Cancer Cell2011，，2： | 3 |
| 19 | Application of machine learning in predicting the rate-dependent compressive strength of rocks显示文摘Accurate prediction of compressive strength of rocks relies on the rate-dependent behaviors of rocks, and correlation among the geometrical, physical, and mechanical properties of rocks. However, these properties may not be easy to control in laboratory experiments, particularly in dynamic compression experiments. By training three machine learning models based on the support vector machine(SVM), backpropagation neural network(BPNN), and random forest(RF) algorithms, we isolated different input parameters, such as static compressive strength, P-wave velocity, specimen dimension, grain size, bulk density, and strain rate, to identify their importance in the strength prediction. Our results demonstrated that the RF algorithm shows a better performance than the other two algorithms. The strain rate is a key input parameter influencing the performance of these models, while the others(e.g. static compressive strength and P-wave velocity) are less important as their roles can be compensated by alternative parameters. The results also revealed that the effect of specimen dimension on the rock strength can be overshadowed at high strain rates, while the effect on the dynamic increase factor(i.e. the ratio of dynamic to static compressive strength) becomes significant. The dynamic increase factors for different specimen dimensions bifurcate when the strain rate reaches a relatively high value, a clue to improve our understanding of the transitional behaviors of rocks from low to high strain rates. | Mingdong Wei Wenzhao Meng Feng Dai Wei Wu | 2022 | Journal of Rock Mechanics and Geotechnical Engineering2022，14，5： | 2 |
| 20 | Role of surface defects of carbon nanotubes on catalytic performance of barium promoted ruthenium catalyst for ammonia synthesis显示文摘Carbon nanotubes(CNTs) with abundant surface defects are prepared by a liquid oxidation and thermal annealing method. The defective CNTs-D supported Ba–Ru/CNTs-D catalysts exhibit superior catalytic performance in ammonia synthesis with a TOF be increased up to 0.30 s-1, which is 2.5 times of oxidized CNTs-O supported Ba–Ru/CNTs-O catalysts and 5 times of the Ba–Ru/CNTs. The characterizations by CO chemisorption, transmission electron microscope, Raman, and X-ray photoelectron spectroscopy revealed that the uniformly well dispersed Ru NPs can be stabilized on the defective sites of CNTs-D. The great improvement of the catalytic performance and stability of the Ba–Ru/CNTs-D is contributed to the strong interaction between Ru NPs and surface defect of the CNTs. | Yongcheng Ma Guojun Lan Wenzhao Fu Ying Lai Wenfeng Han Haodong Tang Huazhang Liu Ying Li | 2020 | Journal of Energy Chemistry2020，29，2： | 2 |
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