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| 1 | Aminoglycoside-induced and non-syndromic hearing loss is associated with the G7444A mutation in the mitochondrial COI/tRNA (Ser(UCN)) genes in two Chinese families显示文摘 | Zhu Y Qian YP Tang XW Wang JD Yang L Liao ZS Li RH Ji JZ Li ZY Chen JF Choo DI Lu JX Guan MX | 2006 | 中国生物学文摘2006，20，4： | 16 |
| 2 | Effect of Selenium Supplementation on Activity and mRNA Expression of Type 1 Deiodinase in Mice With Excessive Iodine Intake显示文摘Objective To investigate the effect of selenium supplementation on the selenium status and selenoenzyme, especially the activity and mRNA expression of type 1 deiodinase (D1) in mice with excessive iodine (EI) intake and to explore the mechanism of selenium intervention on iodine-induced abnormities. Methods Weanling female BALB/c mice were given tap water or 3 mg/L of iodine or supplemented with 0.5 mg/L or 1.0 mg/L of selenium in the presence of excessive iodine for 5 months. Selenium status, thyroid hormone level, hepatic and renal D1 activity and mRNA expression were examined. Results Excessive iodine intake significantly decreased the selenium concentration in urine and liver, and the activity of glutathione peroxidase (GSH-Px) in liver. Meanwhile, serum total T4 (TT4) increased while serum total T3 (TT3) decreased. Hepatic D1 enzyme activity and mRNA expression were reduced by 33% and 86%, respectively. Renal D1 enzyme activity and mRNA were reduced by 30% and 55%, respectively. Selenium supplementation obviously increased selenium concentration, activity of GSH-Px and D1 as well as mRNA expression of D1. However, increasing the supplementation of Se from 0.5 to 1.0 mg/L did not further increase selenoenzyme activity and expression. Conclusion Relative selenium deficiency caused by excessive iodine plays an essential role in the mechanism of iodine-induced abnormalities. An appropriate dose of selenium supplementation exercises a beneficial intervention. | XUE-FENG YANG XIAO-HUI HOU JIAN XW HUAI-LAN GUO CHEN-JIANG YING XIAO-YI CHEN XIU-FA SUN | 2006 | Biomedical and Environmental Sciences2006，19，4： | 5 |
| 3 | A new three-phase culture method for Manila clam, Ruditapes philippinarum, farming in northern China显示文摘 | Zhang GF Yan XW Yang F | 2006 | Aquaculture2006，258，： | 1 |
| 4 | Two new lanostane triterpenoids from Poria cocos显示文摘 | Zheng Y Yang XW | | 0，，3： | 1 |
| 5 | Identification of Nonlinear Characteristics in Cushioning Packaging Using Neural Networks with Fuzzy Adaptive Control显示文摘 | Liang YC Wang Z Yang XW | 1997 | Mechanics Research Communications1997，24，4： | 1 |
| 6 | Hydrotherrnally grown oriented ZnO nanorod arrays for gas sensing applications显示文摘 | JX Wang XW Sun Y Yang | 2006 | Nanotechnology2006，17，： | 1 |
| 7 | Grateloupia longifolia polysaecharide inhibits angiogenesis by downregulating tissue factor expression in HMEC-1 endothelial cells 显示文摘 | Zhang C Yang F Zhang XW | 2006 | Br J Pharmacol2006，148，6： | 1 |
| 8 | Implantation of a self-expandable metallic inverted Y-stent to treat tracheobronchial stenosis in the carinal region:initial clinical experience显示文摘 | YANG RM HAN XW WU G | 2007 | Clin Radiol2007，62，12： | 1 |
| 9 | Influence of variable domain glycosylation on anti-neutrophil cytoplasmic autoantibodies and anti-glomerular basement membrane autoantibodies 显示文摘 | Xu PC Gou S J Yang XW | 2012 | BMC Immunol2012，13，： | 1 |
| 10 | The mismatch DNA repair heterodimer,hMSH2/6,regulates BLM helicase显示文摘 | Yang Q Zhang R Wang XW | 2004 | Oncogene2004，23，： | 1 |
| 11 | Studies of intestinal permeability of 36 flavonoids using Caco-2 cell monolayer model显示文摘 | Tiara X J Yang XW Yang XD | 2009 | Int J Pharm2009，367，12： | 1 |
| 12 | Association between single-nucleotide polymorphisms in pre-miRNAs and the risk of asthma in a Chinese population显示文摘 | Su XW Yang Y Lv ML | 2011 | DNA Cell Biology2011，30，11： | 1 |
| 13 | In vivo tumor co-transfection with superantigen and CD80 induces Systemic immunity without tolerance and prolongs survival in mice with hepatocellular carcinoma显示文摘 | Li ZS Yang XW Chen Z | 2004 | Cancer Biol Ther2004，3，7： | 1 |
| 14 | A new indole derivative isolated from the root of tuber fleeceflower(Polygonum multiflorum)显示文摘 | Gu ZM Ma CM eIal | 1998 | 中草药1998，29，： | 1 |
| 15 | Grateloupia longifolia polysaceharide inhibits angiogenesis by downregulating tissue factor expression in HMEC-1 endothelial cells显示文摘 | Zhang C Yang F Zhang XW | 2006 | Br J Pharmacol2006，148，： | 1 |
| 16 | Bio - assay guided isolation and identifi- cation of ct - glucosidase inhibitors from the leaves of Aquilaria sinen- sis 显示文摘 | Feng J Yang XW Wang RF | 2011 | Phytochem2011，72，23： | 1 |
| 17 | Chitosan nanoparticle as gene therapy vector via gastrointestinal mucosa administration:results of an in vitro and in vivo study显示文摘 | Zheng F Shi XW Yang GF | | 0，，04： | 1 |
| 18 | Efficient derivation of Chinese human embryonic stem cell lines from frozen embryos显示文摘 | Li CL Yang YY Lu XW | | 0，，3： | 1 |
| 19 | Mixed linan-neolignans from Tarenna attenuata 显示文摘 | YANG XW ZHAO PJ MA YL | 2007 | J Nat Prod2007，70，4： | 1 |
| 20 | Implantation of a self- expandable metallic inverted Y-stent to treat tracheobronchial stenosis in the carinal region: initial clinical experience 显示文摘 | Yang RM Han XW Wu G | 2007 | Clin Radiol2007，62，12： | 1 |
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