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| 1 | Characterization of disinfection byproduct formation potential in 13 source waters in China显示文摘The formation potential of four trihalomethanes (THMFP) and seven haloacetic acids (HAA 7 FP) in 13 source waters taken from four major water basin areas in China was evaluated using the simulated distribution system (SDS) chlorination method.The specific ultraviolet absorbance (SUVA 254:the ratio of UV 254 to dissolved organic carbon (DOC)),which ranged between 0.9 and 5.0 L/(mg·m),showed that the organic compounds in different source waters exhibited different reactivities with chlorine.The HAA 7 FP of source waters ranged from 20 to 448 μg/L and the THMFP ranged from 29 to 259 μg/L.The HAA 7 FP concentrations were higher than the THMFP concentrations in all but one of the samples.Therefore,the risks of haloacetic acids (HAAs) should be of concern in some source waters.TCM (chloroform) and BDCM (bromodichloromethane) were the major THM constituents,while TCAA (trichloroacetic acid) and DCAA (dichloroacetic acid) were the major HAA species.Br-THM (brominated THM species) were much higher than BrHAA (brominated HAA species),and the formation of Br-DBP (Br-THM and Br-HAA) should be of concern when the bromide concentration is over 100 μg/L. | Junzhi Zhang Jianwei Yu Wei An Juan Liu Yongjing Wang Youjun Chen Jia Tai Min Yang | 2011 | Journal of Environmental Sciences2011，23，2： | 13 |
| 2 | Dietary supplementation with a high dose of daidzein enhances the antioxidant capacity in swine muscle but experts pro-oxidant function in liver and fat tissues显示文摘Background: Although isoflavones are natural dietary antioxidants, they may have toxicological effects. This study aimed to evaluate the redox system in tissues of finishing pigs by supplementation with high dose of daidzein(640 mg/kg).Results: The supplementation of high dose of daidzein for 64 d increased the activity of superoxide dismutase and total antioxidant capacity in longissimus muscle but down-regulated the expression of reactive oxygen species(ROS)-producing enzyme NADPH oxidase-2 and cyclooxygenase-2. In contrast, high-level supplementation with daidzein exerted pro-oxidant changes in back fat, abdominal fat, liver, and plasma, as reflected by increased contents of malondialdehyde, a lipid peroxidation product, in these tissues. Furthermore, daidzein supplementation resulted in higher expression of ROS-producing enzymes, including NADPH oxidase-1 and cyclooxygenase-1in liver, 5-lipoxygenase(5-LOX) in backfat and NADPH oxidase-2 both in abdominal fat and backfat. The supplementation of daidzein did not affect meat quality parameters in longissimus muscle, including marbling score,eye muscle areas, intramuscular fat, shear force, drip loss, p H and meat color.Conclusions: This experiment suggests that dietary supplementation of finishing pigs with daidzein at a high dose level improves redox status in muscle but exerts pro-oxidant effect in liver and fat tissues. | Wei Chen Xianyong Ma Yingcai Lin Yunxia Xiong Chuntian Zheng Youjun Hu Deqian Yu Zongyong Jiang | 2016 | Journal of Animal Science and Biotechnology2016，7，3： | 8 |
| 3 | Evolutionary trace analysis of eukaryotic DNA topoisomerase I superfamily: Identification of novel antitumor drug binding site显示文摘The studies of novel inhibitors of DNA topoisomerase I (Topo I) have already be-come very promising in cancer chemotherapy. Identifying the new drug-binding residues is playing an important role in the design and optimization of Topo I inhibitors. The designed com-pounds may have novel scaffolds, thus will be helpful to overcome the toxicities of current camptothecin (CPT) drugs and may provide a solution to cross resistance with these drugs. Mul-tiple sequence alignments were performed on eukaryotic DNA topoisomerase I superfamily and thus the evolutionary tree was constructed. The Evolutionary Trace method was applied to iden-tify functionally important residues of human Topo I. It has been demonstrated that class-specific hydrophobic residues Ala351, Met428, Pro431 are located around the 7,9-position of CPT, indi-cating suitable substitution of hydrophobic group on CPT will increase antitumor activity. The conservative residue Lys436 in the superfamily is of particular interest and new CPT derivatives designed based on this residue may greatly increase water solubility of such drugs. It has also been demonstrated that the residues Asn352 and Arg364 were conservative in the superfamily, whose mutation will render CPT resistance. As our molecular docking studies demonstrated they did not make any direct interaction with CPT, they are important drug-binding site residues for future design of novel non-camptothecin lead compounds. This work provided a strong basis for the design and synthesis of novel highly potent CPT derivatives and virtual screening for novel lead compounds. | SONG Yunlong QI Yunpeng ZHANG Wannian SHENG Chunquan ZHANG Min YAO Jianzhong YU Jianxin MIAO Zhenyuan ZHOU Youjun ZHU Ju L(U) Jiaguo | 2005 | Science China(Life Sciences)2005，48，4： | 5 |
| 4 | Grain Growth Behavior of 5Cr21Mn9Ni4N Steel Micro-Alloyed by Rare Earth显示文摘Grain growth behavior of 5Cr21Mn9Ni4NRE steel was experimentally studied at various solid solution treatment temperatures and holding for different times. The experimental results show that the 5Cr21Mn9Ni4NRE steel has the feature of sharp austenite grain coarsening after solid solution treatment at the temperature above 1150 ℃. RE added in the steel has the benefit to restrain grain growth and increase grain growth activation energy. Grain growth mechanism is self-diffusion controlling process. The dispersed carbo-nitride in the steel greatly restrains grain growth. Solid solution treatment at the temperature below 1100 ℃ leads to little increase of grain size and little decrease of Rockwell hardness for mass carbo-nitride undissolved, whereas solid solution treatment at the temperature above 1150 ℃ leads to rapid grain coarsening and Rockwell hardness decrease. Grain growth exponent increases with the increasing solid solution treatment temperature. | Yu Shichang Wu Shenqing Gong Youjun Gong Yuansheng Lian Mingsheng Ye Gang Cheng Yijun | 2006 | Journal of Rare Earths2006，24，1： | 3 |
| 5 | The Gravitational-wave physics Ⅱ: Progress显示文摘It has been a half-decade since the first direct detection of gravitational waves, which signifies the coming of the era of the gravitational-wave astronomy and gravitational-wave cosmology. The increasing number of the detected gravitational-wave events has revealed the promising capability of constraining various aspects of cosmology, astronomy, and gravity. Due to the limited space in this review article, we will briefly summarize the recent progress over the past five years, but with a special focus on some of our own work for the Key Project 'Physics associated with the gravitational waves' supported by the National Natural Science Foundation of China. In particular,(1) we have presented the mechanism of the gravitational-wave production during some physical processes of the early Universe, such as inflation, preheating and phase transition, and the cosmological implications of gravitational-wave measurements;(2) we have put constraints on the neutron star maximum mass according to GW170817 observations;(3) we have developed a numerical relativity algorithm based on the finite element method and a waveform model for the binary black hole coalescence along an eccentric orbit. | Ligong Bian Rong-Gen Cai Shuo Cao Zhoujian Cao He Gao Zong-Kuan Guo Kejia Lee Di Li Jing Liu Youjun Lu Shi Pi Jian-Min Wang Shao-Jiang Wang Yan Wang Tao Yang Xing-Yu Yang Shenghua Yu Xin Zhang | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，12： | 2 |
| 6 | Extremely low penetrance of deafness associated with the mitochondrial 12S rRNA mutation in 16 Chinese families: Implication for early detection and prevention of deafness显示文摘 | Pu Dai Xin Liu Dongyi Han Yaping Qian Deliang Huang Huijun Yuan Weiming Li Fei Yu Ruining Zhang Hongyan Lin Yong He Youjun Yu Quanzhu Sun Huaiyi Qin Ronghua Li Xin Zhang Dongyang Kang Juyang Cao Wie-Yen Young Min-Xin Guan | 2005 | Biochemical and Biophysical Research Communications2005，，1： | 2 |
| 7 | Effect of powders refinement on the tribological behavior of Ni-based composite coatings by laser cladding显示文摘 | Lingqian Wang Jiansong Zhou Youjun Yu Chun Guo Jianmin Chen | 2012 | Applied Surface Science2012，，17： | 2 |
| 8 | Investigation on compounding and application of C80–C100 high-performance concrete显示文摘 | Jian Yin Shiqiong Zhou Youjun Xie Yu Chen Qinlian Yan | 2002 | Cement and Concrete Research2002，，2： | 1 |
| 9 | Effects of WC–Ni content on microstructure and wear resistance of laser cladding Ni-based alloys coating显示文摘 | Chun Guo Jianmin Chen Jiansong Zhou Jierong Zhao Lingqian Wang Youjun Yu Huidi Zhou | 2011 | Surface & Coatings Technology2011，，8： | 1 |
| 10 | Ultra-robust stretchable electrode for e-skin:In situ assembly using a nanofiber scaffold and liquid metal to mimic water-to-net interaction显示文摘The development of stretchable electronics could enhance novel interface structures to solve the stretchability-conductivity dilemma,which remains a major challenge.Herein,we report a nano-liquid metal(LM)-based highly robust stretchable electrode(NHSE)with a self-adaptable interface that mimics water-tonet interaction.Based on the in situ assembly of electrospun elastic nanofiber scaffolds and electrosprayed LM nanoparticles,the NHSE exhibits an extremely low sheet resistance of 52 mΩsq^(-1).It is not only insensitive to a large degree of mechanical stretching(i.e.,350%electrical resistance change upon 570%elongation)but also immune to cyclic deformation(i.e.,5%electrical resistance increases after 330000 stretching cycles with 100%elongation).These key properties are far superior to those of the state-of-the-art reports.Its robustness and stability are verified under diverse circumstances,including long-term exposure to air(420 days),cyclic submersion(30000 times),and resilience against mechanical damages.The combination of conductivity,stretchability,and durability makes the NHSE a promising conductor/electrode solution for flexible/stretchable electronics for applications such as wearable on-body physiological signal detection,human-machine interaction,and heating e-skin. | Jinwei Cao Fei Liang Huayang Li Xin Li Youjun Fan Chao Hu Jing Yu Jin Xu Yiming Yin Fali Li Dan Xu Hanfang Feng Huali Yang Yiwei Liu Xiaodong Chen Guang Zhu Run-Wei Li | 2022 | InfoMat2022，4，4： | 1 |
| 11 | Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallma 显示文摘 | Kegong Tian Xiuling Yu Tiezhu Zhao Youjun Feng | 2007 | PLOS ONE2007，，6： | 1 |
| 12 | Preparation, microstructure and tribological behavior of laser cladding NiAl intermetallic compound coatings显示文摘 | Youjun Yu Jiansong Zhou Jianmin Chen Huidi Zhou Chun Guo Lingqian Wang Lianbin Yang | 2011 | Wear2011，，： | 1 |
| 13 | Effect of powders refinement on the tribological behavior of Ni-based composite coatings by laser cladding显示文摘 | Lingqian Wang Jiansong Zhou Youjun Yu Chun Guo Jianmin Chen | 2012 | Applied Surface Science2012，，17： | 1 |
| 14 | Effects of WC–Ni content on microstructure and wear resistance of laser cladding Ni-based alloys coating显示文摘 | Chun Guo Jianmin Chen Jiansong Zhou Jierong Zhao Lingqian Wang Youjun Yu Huidi Zhou | 2011 | Surface & Coatings Technology2011，，8： | 1 |
| 15 | Microstructure and tribological properties of Ti-Cu intermetallic compound coating 显示文摘 | Guo Chun Zhou Jiansong Yu Youjun | 2012 | MaterialsandDesign2012，36，： | 1 |
| 16 | Effect of powders refinement on the tribological behavior of Ni based composite coatings by laser cladding显示文摘 | Lingqian Wang Jiansong Zhou Youjun Yu | 2012 | Applied Surface Science2012，258，66： | 1 |
| 17 | Geochemical characteristics of Ordovician crude oils in the northwest of the Tahe oil field, Tarim Basin显示文摘Forty-six crude oil samples were selected from the Ordovician in the northwestern part of the Tahe oilfield for detailed molecular geochemical and isotopic analysis, including group compositions, carbonhydrogen isotopes and gas chroma-tograms of saturated hydrocarbons, as well as the characteristics of terpane, sterane and other biomarkers, indicating that crude oils are of the same origin from different districts in the Tahe oilfield and were derived from the same source kitchen (or oil source formation), i.e., mainly stemming from marine hydrocarbons. Detailed studies of oil physical properties of 25-honpane revealed that such oils have heavy or thick oil qualities due to biodegradation. Comprehensive assessment in terms of five maturity parameters shows that the oils from the Ordovician with Ro values varying from 0.80% to 1.59% are widely distributed in the northwest of the Tahe oilfield. | YU Qiuhua WEN Zhigang TANG Youjun | 2011 | Chinese Journal Of Geochemistry2011，30，1： | 1 |
| 18 | High-Temperature Oxidation Behavior of 5Cr21Mn9Ni4N Steel Micro-Alloyed by Rare Earth显示文摘The oxidation resistance of 5Cr21Mn9Ni4N steel micro-alloying by RE at 700~900 ℃ was investigated. The results indicate that oxidation exponent n and oxidation activation energy are increased, and oxidation velocity constant k_p is decreased when 0.2% RE is added in 5Cr21Mn9Ni4N steel. The addition of RE elements does not alter phase constitution of oxidation scale, however it improves the configuration of oxidation scale, and increases thermal stability and adhesivity of oxidation scale, which results in the raise of oxidation resistance of 5Cr21Mn9Ni4N steel at high temperature. The oxidation scale constitutes of refractory steel transfer from manganic oxide mostly to ferric oxide mostly with the increase of temperature, which leads to descend of compactness and desquamation resistance of oxidation scale. The mass increase of ferric oxide in the oxidation scale and the looseness of oxidation scale are the main reason to descend the oxidation resistance of refractory steel. | Yu Shichang Wu Shenqing Gong Youjun Gong Yuansheng Lian Mingsheng Ye Gang Cheng Yijun | 2006 | Journal of Rare Earths2006，24，3： | 1 |
| 19 | High temperature wear resistance of laser cladding NiCrBSi and NiCrBSi/WC-Ni composite coatings显示文摘 | Chun Guo Jiansong Zhou Jianmin Chen Jierong Zhao Youjun Yu Huidi Zhou | 2011 | Wear2011，，7： | 1 |
| 20 | High temperature wear resistance of laser cladding NiCrBSi and NiCrBSi/WC-Ni composite coatings显示文摘 | Chun Guo Jiansong Zhou Jianmin Chen Jierong Zhao Youjun Yu Huidi Zhou | 2011 | Wear2011，，7： | 1 |
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