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| 1 | Investigation into the Vibration of Metro Bogies Induced by Rail Corrugation显示文摘The current research of rail corrugation mainly focuses on the mechanisms of its formation and development. Compared with the root causes and development mechanisms, the wheel–rail impacts, the fatigue failure of vehicle-track parts, and the loss of ride comfort due to rail corrugation should also be taken into account. However, the influences of rail corrugation on vehicle and track vibration, and failure of vehicle and track structural parts are barely discussed in the literature. This paper presents an experimental and numerical investigation of the structural vibration of metro bogies caused by rail corrugation. Extensive experiments are conducted to investigate the effects of short-pitch rail corrugation on the vibration accelerations of metro bogies. A dynamic model of a metro vehicle coupled with a concrete track is established to study the influence of rail corrugation on the structural vibration of metro bogies. The field test results indicate that the short-pitch rail corrugation generates strong vibrations on the axle-boxes and the bogie frames, therefore, accelerates the fatigue failure of the bogie components. The numerical results show that short-pitch rail corrugation may largely reduce the fatigue life of the coil spring, and improving the damping value of the primary vertical dampers is likely to reduce the strong vibration induced by short-pitch rail corrugation. This research systematically studies the effect of rail corrugation on the vibration of metro bogies and proposes some remedies for mitigating strong vibrations of metro bogies and reducing the incidence of failure in primary coil springs, which would be helpful in developing new metro bogies and track maintenance procedures. | LING Liang LI Wei FOO Elbert WU Lei WEN Zefeng JIN Xuesong | 2017 | Chinese Journal of Mechanical Engineering2017，30，1： | 8 |
| 2 | Characteristics of pantograph‐catenary arc under low air pressure and strong airflow显示文摘Pantograph‐catenary arc fault is the primary factor threatening the stability of the power transmission for high‐speed railway.The motion characteristics of the pantograph‐catenary arc under low air pressure and strong airflow is significantly different from the case under atmospheric pressure.In this paper,an experimental platform of panto-graph‐catenary arc was built to investigate arc root position‐time and arc column lon-gitudinal drift height‐time characteristic curves under different air pressures and airflow velocites.Via analysing the corresponding results,it can be found that there are different arc root-arc column traction mechanisms at different stages of arc development.The arcing time and arc root stagnation time under low air pressure are significantly longer than the case under atmospheric pressure,resulting in more serious electrode ablation.The arc column longitudinal drift velocity and height are greater with the increase of airflow velocity.Two typical irregular arc motion phenomena-arc root jumping and arc reignition are observed.To clarify the internal mechanism of the above phenomenon,a magnetohydrodynamics(MHD)model of the pantograph‐catenary arc was lauched,the influence mechanism of the pantograph‐catenary arc temperature and voltage are studied,and the physical process of arc temperature oscillation is analysed.The research results provide theoretical support for arc protection in high‐altitude areas. | Zhilei Xu Guoqiang Gao Wenfu Wei Zefeng Yang Wenhan Xie Keliang Dong Yaguang Ma Yan Yang Guangning Wu | 2022 | High Voltage2022，7，2： | 7 |
| 3 | SPSBl-mediated HnRNP A1 alternative splicing and cell ubiquitylation regulates migration in EGF signaling显示文摘细胞外的信号被显示了影响拼接的其他的 pre-mRNA;然而,分子的机制和导致信号的拼接的规定的生物意义仍然保持大部分未知。这里,我们报导那个表皮的生长因素(EGF ) 通过一个著名拼接管理者的 ubiquitylation 导致拼接的变化, hnRNP A1。EGF 发信号 upregulates 一个 E3 ubiquitin (Ub ) ligase 适配器,敏捷的包含域的 SOCS 盒子蛋白质 1 (SPSB1 ) ,它结合离氨酸 29 连接 polyUb 链到 hnRNP A1 上的成员 Elongin B/C-Cullin 建筑群。重要地, hnRNP A1 的 SPSB1 和 ubiquitylation 在驾驶 EGF 的房间移植有一个关键角色。机械学地,和 SR 蛋白质 kinases (SRPK ) 的激活的 hnRNP A1 的导致 EGF 的 ubiquitylation 导致拼接的 Rac1 的 upregulation isoform, Rac1b,支持房间活动性。这些调查结果解开在蛋白质 ubiquitylation 并且在 EGF/EGF 受体发信号的其他的拼接之间的新奇串音,并且在 modulating 房间移植识别新 EGF/SPSB1/hnRNP A1/Rac1 轴,它可以为癌症治疗有重要含意。 | Feng Wang Xing Fu Peng Chen Ping Wu Xiaojuan Fan Na Li Hong Zhu Ting-Ting Jia Hongbin Ji Zefeng Wang Catherine C L Wong Ronggui Hu Jingyi Hui | 2017 | Cell Research2017，27，4： | 5 |
| 4 | Force/Moment Isotropy of 8/4-4 Parallel Six-Axis Force Sensor Based on Performance Atlases显示文摘A six-axis force sensor with parallel 8/4-4 structure is introduced and its measurement principle is analyzed.Based on condition numbers of Jacobian matrix spectral norm of the sensor,the relationship between the force and moment isotropy and some structural parameters is deduced.Orthogonal test methods are used to determine the degree of primary and secondary factors that have significant effect on sensor characteristics.Furthermore,the relationship between each performance index and the structural parameters of the sensor is analyzed by the method of the atlas,which lays a foundation for structural optimization design of the force sensor. | Song Weishan Li Chenggang Wang Chunming Song Yong Wu Zefeng Rajnathsing Hemant | 2018 | Transactions of Nanjing University of Aeronautics and Astronautics2018，35，6： | 3 |
| 5 | Numerical Analysis of Rolling-sliding Contact with the Frictional Heat in Rail显示文摘Thermal damage caused by frictional heat of rolling-sliding contact is one of the most important failure forms of wheel and rail.Many studies of wheel-rail frictional heating have been devoted to the temperature field,but few literatures focus on wheel-rail thermal stress caused by frictional heating.However,the wheel-rail creepage is one of important influencing factors of the thermal stress.In this paper,a thermo-mechanical coupling model of wheel-rail rolling-sliding contact is developed using thermo-elasto-plastic finite element method.The effect of the wheel-rail elastic creepage on the distribution of heat flux is investigated using the numerical model in which the temperature-dependent material properties are taken into consideration.The moving wheel-rail contact force and the frictional heating are used to simulate the wheel rolling on the rail.The effect of the creepage on the temperature rise,thermal strain,residual stress and residual strain under wheel-rail sliding-rolling contact are investigated.The investigation results show that the thermally affected zone exists mainly in a very thin layer of material near the rail contact surface during the rolling-sliding contact.Both the temperature and thermal strain of rail increase with increasing creepage.The residual stresses induced by the frictional heat in the surface layer of rail appear to be tensile.When the creepage is large,the frictional heat has a significant influence on the residual stresses and residual strains of rail.This paper develops a thermo-mechanical coupling model of wheel-rail rolling-sliding contact,and the obtained results can help to understand the mechanism of wheel/rail frictional thermal fatigue. | LI Wei WEN Zefeng JIN Xuesong WU Lei | 2014 | Chinese Journal of Mechanical Engineering2014，27，1： | 2 |
| 6 | Multi-physics analysis and optimisation of high-speed train pantograph-catenary systems allowing for velocity skin effect显示文摘A pantograph-catenary system (PCS) - an essential component to supply a high-speed train (HST) - faces a variety of new challenges due to the continuously increasing train speeds. The HST traction system receives power via an electrical contact between the pantograph strip and the high-voltage contact wire. This electrical contact is subject to serious mechanical shocks and significant electrochemical corrosion, making the modelling of the dynamic processes complicated, especially under high-speed and heavy-load conditions. The damage to the PCS - which is particularly noticeable at the edges of the pantograph strip - may become severe as the speed of the train rises. Moreover, as the speed increases, the distribution of the electrical current in the strip becomes uneven due to the velocity skin effect (VSE). To assess the impact of the VSE on the performance of PCSs, a multi-physics model has been created and is reported in this study. The model has been validated through experiments and the main aspects of its functionality - such as the VSE, friction, and air convection - have been identified and analysed at different speeds. The impact of speed on the traction current and the behaviour of thermal sources have been explored. With the increasing speed, the phenomenon of current clustering at the trailing edge of the strip becomes quite dramatic, resulting in a thermal surge in the region of the strip with high current density. To mitigate the negative impact caused by VSE in the PCSs, an improved kriging optimisation methodology has been utilised to optimise the parameters of the PCS. Recommendations regarding the optimal design of the PCS are put forward to improve the current-carrying performance and reduce the local temperature rise in the strip. | Xianrui Liu Zefeng Yang Song Xiao Xuwei Duan Guoqiang Gao Wenfu Wei Guangning Wu Mihai Rotaru Jan K.Sykulski | 2020 | High Voltage2020，5，6： | 2 |
| 7 | Application of fluorescence in situ hybridization in the detection of bladder transitional-cell carcinoma: A multi-center clinical study based on Chinese population显示文摘Objective:To evaluate the diagnostic value of fluorescence in situ hybridization(FISH)in bladder cancer.Methods:We enrolled healthy volunteers and patients who were clinically suspected to have bladder cancer and conducted FISH tests and cytology examinations from August 2007 to December 2008.Receiver operating characteristic(ROC)curve analysis was performed and the area under curve(AUC)values were calculated for both the FISH and urine cytology tests.Results:A cohort of 988 healthy volunteers was enrolled to establish a reference range for the normal population.A total of 4807 patients with hematuria were prospectively,randomly enrolled for the simultaneous analysis of urine cytology,FISH testing,and a final diagnosis as determined by the pathologic findings of a biopsy or a surgically-excised specimen.Overall,the sensitivity of FISH in detecting transitional-cell carcinoma was 82.7%,while that of cytology was 33.4%(p<0.001).The sensitivity values of FISH for non-muscle invasive and muscle invasive bladder transitional-cell carcinoma were 81.7%and 89.6%,respectively(p=0.004).The sensitivity values of FISH for low and high grade bladder cancer were 82.6%and 90.1%,respectively(p=0.002).Conclusion:FISH is significantly more sensitive than voided urine cytology for detecting bladder cancer in patients evaluated for gross hematuria at all cancer grades and stages.Higher sensitivity using FISH was obtained in high grade and muscle invasive tumors. | Liqun Zhou Kaiwei Yang Xuesong Li Yi Ding Dawei Mu Hanzhong Li Yong Yan Jinyi Li Dongwen Wang Wei Li Yulong Cong Jiangping Gao Kewei Ma Yajun Xiao Sheng Zhang Hongyi Jiang Weilie Hu Qiang Wei Xunbo Jin Zhichen Guan Qingyong Liu Danfeng Xu Xin Gao Yongguang Jiang Weimin Gan Guang Sun Qing Wang Yanhui Liu Jianquan Hou Liping Xie Xishuang Song Fengshuo Jin Jiafu Feng Ming Cai Zhaozhao Liang Jie Zhang Dingwei Ye Lin Qi Lulin Ma Jianzhong Shou Yuping Dai Jianyong Shao Ye Tian Shizhe Hong Tao Xu Chuize Kong Zefeng Kang Yuexin Liu Xun Qu Benkang Shi Shaobin Zheng Yi Lin Shujie Xia Dong Wei Jianbo Wu Weiling Fu Zhiping Wang Jianbo Liang | 2019 | Asian Journal of Urology2019，6，1： | 2 |
| 8 | Effects of Structure Elastic Deformations of Wheelset and Track on Creep Forces of Wheel/Rail in Rolling Contact显示文摘 | JIN Xuesong WU Pingbo WEN Zefeng | 2002 | Wear2002，253，： | 1 |
| 9 | Study on the erosion characteristics of copper-carbon electrode pairs by DC air arc显示文摘As common electric contact materials,copper-carbon electrode pairs are widely used in the field of electric contact such as in high-speed railways,motor collector rings and grounding brushes.They play a key role in energy transmission in the above-mentioned systems.Arc erosion has become a key issue threatening system safety.In this work,a dedicated arc erosion platform was built to study the polarity effect of copper-carbon electrode pairs.It was found that arc dynamics and electrodes erosion behaviours were significantly different under different polarities,which could be understood from the mechanism of heat transfer,cooling and electron emission of the electrode.Then,when the carbon material was used as an anode,the arc caused carbon transfer:the carbon material sublimated quickly due to electron condensation and thermal conduction and quickly condensed on the low-temperature metal electrode,while the carbon material transfer could partly inhibit the oxidation of the cathode metal electrode.In addition,the rapid sublimation of the carbon material produced high-temperature airflow,which would make the arc impedance fluctuate and cause the arc voltage to jump.Finally,the anode heat transfer and cathode cooling mechanism directly affected the material state,and the erosion of the anode material was more serious。 | Wenhan Xie Guangning Wu Zefeng Yang Pengpeng She Hong Wang Haozi Zuo Wenfu Wei Guoqiang Gao Chuanjun Tu | 2021 | High Voltage2021，6，4： | 1 |
| 10 | Three-dimensional elastic-plastic stress analysis of wheel-rail rolling contact显示文摘 | Wen Zefeng Wu Lei Li Wei | 2011 | Wear2011，271，12： | 1 |
| 11 | Effects ofstructure elastic deformations of wheelset and track oncreep forces of wheel/rail in rolling contact显示文摘 | JIN Xuesong WU Pingbo WEN Zefeng | 2002 | Wear2002，253，： | 1 |
| 12 | Three-dimensional elastic-plastic stress analysis of wheel-rail rolling contact 显示文摘 | Wen Zefeng Wu Lei Li Wei Jin Xuesong Zhu Minhao | 2011 | Wear2011，271，12： | 1 |
| 13 | Effects of structure elastic deformations of wheelset and track on creep forces of wheel/rail in rolling contact显示文摘 | JIN Xuesong WU Pingbo WEN Zefeng | 2002 | Wear2002，253，1： | 1 |
| 14 | Stretchable and Superhydrophilic Polyaniline/Halloysite Decorated Nanofiber Composite Evaporator for High Efficiency Seawater Desalination显示文摘Here,authors report on composition of a stretchable,mechanically durable and superhydrophilic polyaniline(PANI)/hal-loysite nanotubes(HNTs)decorated PU nanofiber(PANI/HNTs@PU).The polymer nanofibers are placed as the core and PANI/HNTs makes the shell section.The PANI/HNTs creates a membrane with outstanding light absorption and photo-thermal conversion performance.The strong solar absorption capability and superhydrophilicity of the PANI/HNTs@PU remain almost unchanged during stretching,abrasion,and ultrasonic washing tests,exhibiting superior surface stability and durability.When the PANI/HNTs@PU is used for the interfacial evaporation,the evaporation rate and efficiency reach as high as 1.61 kg m^(-2) h^(-1) and 94.7%,respectively.No salt precipitation is observed on the solar absorber surface even under a high salinity or during the long term or cyclic evaporation test.Furthermore,the excellent interfacial evaporation function is maintained when the nanofiber composite is mechanically stretched.The PANI/HNTs@PU based evaporation device shows promising applications in high performance solar desalination. | Jiang Han Wenqian Xing Jun Yan Jing Wen Yuntao Liu Yuqing Wang Zefeng Wu Longcheng Tang Jiefeng Gao | 2022 | Advanced Fiber Materials2022，4，5： | 1 |
| 15 | Dynamic stress analysis of rail joint with height difference defect using finite element method 显示文摘 | Wu Cai Zefeng Wen Xuesong Jin | 2007 | Engineering Failure Analysis2007，14，8： | 1 |
| 16 | Genome Sequence o显示文摘 | Zefeng Li Sanling Wu Xuefei Bai | 2011 | J Bacteriol2011，139，21： | 1 |
| 17 | Pijx confers broad-spectrum seedling and panicle blast resistance by promoting the degradation of ATP β subunit and OsRbohC-mediated ROS burst in rice显示文摘Rice blast,caused by the fungal pathogen Magnaporthe oryzae,is one of the most important diseases of rice.Utilization of blast-resistance genes is the most economical,effective,and environmentally friendly way to control the disease.However,genetic resources with broad-spectrum resistance(BSR)that is effective throughout the rice growth period are rare.In this work,using a genome-wide association study,we identify a new blast-resistance gene,Pijx,which encodes a typical CC-NBS-LRR protein.Pijx is derived from a wild rice species and confers BSR to M.oryzae at both the seedling and panicle stages.The functions of the resistant haplotypes of Pijx are confirmed by gene knockout and overexpression experiments.Mechanistically,the LRR domain in Pijx interacts with and promotes the degradation of the ATP synthase β subunit(ATPb)via the 26S proteasome pathway.ATPb acts as a negative regulator of Pijx-mediated panicle blast resistance,and interacts with OsRbohC to promote its degradation.Consistently,loss of ATPb function causes an increase in NAPDH content and ROS burst.Remarkably,when Pijx is introgressed into two japonica rice varieties,the introgression lines show BSR and increased yields that are approximately 51.59%and 79.31%higher compared with those of their parents in a natural blast disease nursery.In addition,we generate PPL^(Pijx Pigm) and PPL^(Pijx Piz-t) pyramided lines and these lines also have higher BSR to panicle blast compared with Pigm-or Piz-t-containing rice plants.Collectively,this study demonstrates that Pijx not only confers BSR to M.oryzae but also maintains high and stable rice yield,providing new genetic resources and molecular targets for breeding rice varieties with broad-spectrum blast resistance. | Ning Xiao Yunyu Wu Xiaoxiang Zhang Zeyun Hao Zichun Chen Zefeng Yang Yue Cai Ruyi Wang Ling Yu Zhiping Wang Yue Lu Wei Shi Cunhong Pan Yuhong Li Changhai Zhou Jianju Liu Niansheng Huang Guangqing Liu Hongjuan Ji Shuhao Zhu Shuai Fang Yuese Ning Aihong Li | 2023 | Molecular Plant2023，16，11： | 0 |
| 18 | Establishment of correlation between reaction kinetics and carbon structures in the char gasification process显示文摘For a gasification process,the char-CO_(2)gasification is the controlling step worthwhile to be deeply investigated.The article chosen corn stalk(CS),poplar sawdust(PS)and bagasse residue(BR)as the typical waste species derived from agricultural,forestal and industrial sources.The char-CO_(2)gasification behavior,reaction kinetics and carbon structure were studied to reveal the intrinsic factors determining the reaction kinetics.Generally,the carbon conversion and maximum conversion rate were influenced by the feedstocks species and char preparation temperatures,as influenced by ash proportion,potassium content in ash and carbon structure of char.The char-CO_(2)reaction for CS was subject more to the catalytic effect of alkali compositions,while pore structure affected more the gasification reaction for PS char.The isoconversional kinetic analysis indicated that the gasification reaction became stable at carbon conversion of 0.5.Subsequently,sectionalized kinetic parameters were calculated for the initial gasification temperature to the temperature reaching 50%conversion.The result showed that high initial gasification temperature increased the char-CO_(2)gasification barrier to hardly start the reaction but accelerate the reaction rate.The carbon structure analyses further clarified that the reaction activation energy was highly related to the microcrystalline structure of carbon,while the reaction rate was more determined by carbon pore structure. | Zefeng Ge Xi Cao Zhenting Zha Yuna Ma Mingxun Zeng Yuqing Wu Zenghui Hou Huiyan Zhang | 2023 | Carbon Resources Conversion2023，6，2： | 0 |
| 19 | COVID-19 induces new-onset insulin resistance and lipid metabolic dysregulation via regulation of secreted metabolic factors显示文摘Abnormal glucose and lipid metabolism in COVID-19 patients were recently reported with unclear mechanism.In this study,we retrospectively investigated a cohort of COVID-19 patients without pre-existing metabolic-related diseases,and found new-onset in suli n resista nee,hyperglycemia,and decreased HDL-C in these patie nts.Mecha nistically,SARS-CoV-2 infecti on in creased the expression of RE1-silencing transcription factor(REST),which modulated the expression of secreted metabolic factors including myeloperoxidase,apelin,and myostatin at the transcriptional level,resulting in the perturbation of glucose and lipid metabolism.Furthermore,several lipids,including(±)5-HETE,(±)12-HETE,propionic acid,and isobutyric acid were identified as the potential biomarkers of COVID-19-induced metabolic dysregulation,especially in insulin resistance.Taken together,our study revealed insulin resistance as the direct cause of hyperglycemia upon COVID-19,and further illustrated the underlying mechanisms,providing potential therapeutic targets for COVID-19-induced metabolic complications. | Xi He Chenshu Liu Jiangyun Peng Zilun Li Fang Li Jian Wang Ao Hu Meixiu Peng Kan Huang Dongxiao Fan Na Li Fuchun Zhang Weiping Cai Xinghua Tan Zhongwei Hu Xilong Deng Yueping Li Xiaoneng Mo Linghua Li Yaling Shi Li Yang Yuanyuan Zhu Yanrong Wu Huichao Liang Baolin Liao Wenxin Hong Ruiying He Jiaojiao Li Pengle Guo Youguang Zhuo Lingzhai Zhao Fengyu Hu Wenxue Li Wei Zhu Zefeng Zhang Zeling Guo Wei Zhang Xiqiang Hong Wei kang Cai Lei Gu Ziming Du Yang Zhang Jin Xu Tao Zuo Kai Deng Li Yan Xinwen Chen Sifan Chen Chunliang Lei | 2022 | Signal Transduction and Targeted Therapy2022，7，1： | 0 |
| 20 | Gaps,challenges and possible solution for prediction of wheel-rail rolling contact fatigue crack initiation显示文摘The prediction of wheel/rail rolling contact fatigue(RCF)crack initiation during railway operations is an important task.Since RCF crack evolution is influenced by many factors,its prediction process is complex.This paper reviews the existing approaches to predict RCF crack initiation.The crack initiation region is predicted by the shakedown map.By combining the shakedown map with various initiation criteria and the critical plane method,the crack initiation life is calculated.The classification,methodologies,theories and applications of these approaches are included in this paper.The advantages and limitations of these methods are analyzed to provide recommendation for RCF crack initiation prediction.This review highlights that wheel/rail dynamic characteristic,complex working conditions,surface defects and wear all affect the RCF crack initiation.The optimal selection of criteria is essential in the crack initiation prediction.Based on the research gap regarding the challenging process of crack initiation prediction detailed in this review,a proposed prediction process of RCF crack initiation is proposed to achieve a more accurate result. | Shuyue Zhang Qiyue Liu Maksym Spiryagin Qing Wu Haohao Ding Zefeng Wen Wenjian Wang | 2023 | Railway Engineering Science2023，31，3： | 0 |
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