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| 1 | Serum IL-10 from systemic lupus erythematosus patients suppresses the differentiation and function of monocyte-derived dendritic cells显示文摘The role played by cytokines,other than interferon(IFN)-α,in the differentiation and function of dendritic cells(DCs) in systemic lupus erythematosus(SLE),remains unclear.Serum interleukin-10(IL-10) levels are generally elevated in SLE patients,which might modulate the differentiation of DCs.In this study,DCs were induced from monocytes either by transendothelial trafficking or by culture with granulocyte-macrophage colony-stimulating factor(GM-CSF) + IL-4 + tumor necrosis factor(TNF)-α.Both systems were used to investigate the effects of elevated serum IL-10 level on DC differentiation in SLE patients.The results showed that monocyte-derived DCs induced by either SLE serum or exogenous IL-10 reduced the expression of human leukocyte antigen(HLA)-DR and CD80,decreased IL-12p40 level,and increased IL-10 level,and exhibited an impaired capacity to stimulate allogenic T-cell proliferation.These results indicate that serum IL-10 may be involved in the pathogenesis of SLE by modulating the differentiation and function of DCs. | Zhida Sun Rong Zhang Huijuan Wang Pengtao Jiang Jiangquan Zhang Mingshun Zhang Lei Gu Xiaofan Yang Miaojia Zhang Xiaohui Ji | 2012 | The Journal of Biomedical Research2012，26，6： | 3 |
| 2 | Anisotropic MOF-on-MOF Growth of Isostructural Multilayer Metal–Organic Framework Heterostructures显示文摘Isostructural MOFs with similar crystallographic parameter are easily available for MOF-on-MOF growth and possible to form core–shell structure by isotropic growth.However,due to well-matched cell lattice,selective growth in isostructural MOF heterostructures remains a great challenge for engineering atypical MOF heterostructures.Herein,an anisotropic MOF-onMOF growth strategy was developed to structure a range of multilayer sandwich-like ZIF-L heterostructures via stacking isostructural ZIF-L-Zn and ZIF-L-Co alternately with three-,five-,seven-,and more layer structures.Moreover,these heterostructures with highly designable feature were fantastic precursors for fabricating derivatives with tunable magnetic and catalytic properties.Such strategy explores a novel way of achieving anisotropic MOF-on-MOF growth between isostructural MOFs and opens up new horizons for regulating the properties by MOF modular assembly in versatile functional nanocomposites. | Zhida Gu Wenlei Zhang Ting Pan Yu Shen Peishan Qin Peng Zhang Xiaohan Li Liwei Liu Linjie Li Yu Fu Weina Zhang Fengwei Huo | 2021 | Research2021，，1： | 1 |
| 3 | Anisotropic MOF-on-MOF Growth of Isostructural Multilayer Metal–Organic Framework Heterostructures显示文摘Isostructural MOFs with similar crystallographic parameter are easily available for MOF-on-MOF growth and possible to form core–shell structure by isotropic growth.However,due to well-matched cell lattice,selective growth in isostructural MOF heterostructures remains a great challenge for engineering atypical MOF heterostructures.Herein,an anisotropic MOF-onMOF growth strategy was developed to structure a range of multilayer sandwich-like ZIF-L heterostructures via stacking isostructural ZIF-L-Zn and ZIF-L-Co alternately with three-,five-,seven-,and more layer structures.Moreover,these heterostructures with highly designable feature were fantastic precursors for fabricating derivatives with tunable magnetic and catalytic properties.Such strategy explores a novel way of achieving anisotropic MOF-on-MOF growth between isostructural MOFs and opens up new horizons for regulating the properties by MOF modular assembly in versatile functional nanocomposites. | Zhida Gu Wenlei Zhang Ting Pan Yu Shen Peishan Qin Peng Zhang Xiaohan Li Liwei Liu Linjie Li Yu Fu Weina Zhang Fengwei Huo | 2022 | Research2022，，1： | 0 |
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