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4篇 您的检索式:作者名="A.Mills"
    题名 作者 年代 出处 被引量
1Generation of Transgene‐Free Lung Disease‐Specific Human Induced Pluripotent Stem Cells Using a Single Excisable Lentiviral Stem Cell Cassette显示文摘AbaSomers Jyh‐ChangJean Cesar A.Sommer AmelOmari Christopher C.Ford Jason A.Mills LeiYing Andreia GianottiSommer Jenny M.Jean Brenden W.Smith RobertLafyatis Marie‐FranceDemierre Daniel J.Weiss Deborah L.French PaulGadue George J.Murphy GustavoMostoslavsky 2010STEM CELLS2010,,10:1
2A solid-phase extraction approach for the identification of pharmaceutical–sludge adsorption mechanisms显示文摘It is important to understand the adsorption mechanism of chemicals and active pharmaceutical ingredients(API) on sewage sludge since wastewater treatment plants are the last barrier before the release of these compounds to the environment. Adsorption models were developed considering mostly hydrophobic API–sludge interaction. They have poor predictive ability, especially with ionisable compounds. This work proposes a solid-phase extraction(SPE) approach to estimate rapidly the API–sludge interaction. Sludge-filled SPE cartridges could not be percolated with API spiked mobile phases so different powders were tested as SPE sludge supports. Polytetrafluoroethylene(PTFE) was selected and tested at different PTFE/sludge ratios under eight different adsorption conditions with three API ionisable compounds. The PTFE/sludge mixtures with 50% or less sludge could be used in SPE mode for API sorption studies with methanol/water liquid phases. The results gave insights into API–sludge interactions.It was found that π–π, hydrogen-bonding and charge–charge interactions were as important as hydrophobicity in the adsorption mechanism of charged APIs on sludge.Laurence Berthod Gary Roberts Graham A.Mills 2014Journal of Pharmaceutical Analysis2014,4,2:0
3Paving the way toward retinal regeneration with mesencephalic astrocyte-derived neurotrophic factor显示文摘Neurodegenerative diseases are a leading cause of disability worldwide,and despite significant resources put toward the discovery of potential therapeutic targets,there are currently no effective treatments.The rise of methods to derive and propagate stem cells in vitro offeredElizabeth A.Mills Daniel Goldman 2017Eye Science2017,32,1:0
4TREMble Before TREM2:The Mighty Microglial Receptor Conferring Neuroprotective Properties in TDP-43 Mediated Neurodegeneration显示文摘Microglia were long hailed as solely infammatory cells,and though they are responsible for the brain's immuneresponse,they perform a variety of neuroprotective func-tions including the clearance of cellular and toxic debris^([1]).One toxic molecule known to be cleared by microglia isthe protein aggregate found in Alzheimer's Disease(AD),amyloid-B.William A.Mills III Ukpong B.Eyo 2023Neuroscience Bulletin2023,39,1:0
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