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1Hepatic flow is an intraoperative predictor of early allograft dysfunction in whole-graft deceased donor liver transplantation: An observational cohort study显示文摘BACKGROUND Early allograft dysfunction(EAD)after liver transplantation(LT)is an important cause of morbidity and mortality.To ensure adequate graft function,a critical hepatocellular mass is required in addition to an appropriate blood supply.We hypothesized that intraoperative measurement of portal venous and hepatic arterial flow may serve as a predictor in the diagnosis of EAD.AIM To study whether hepatic flow is an independent predictor of EAD following LT.METHODS This is an observational cohort study in a single institution.Hepatic arterial blood flow and portal venous blood flow were measured intraoperatively by transit flow.EAD was defined using the Olthoff criteria.Univariate and multivariate analyses were used to determine the intraoperative predictors of EAD.Survival analysis and prognostic factor analysis were performed using the Kaplan-Meier and Cox regression models.RESULTS A total of 195 liver transplant procedures were performed between January 2008 and December 2014 in 188 patients.A total of 54(27.7%)patients developed EAD.The median follow-up was 39 mo.Portal venous flow,hepatic arterial flow(HAF)and total hepatic arterial flow were associated with EAD in both the univariate and multivariate analyses.HAF is an independent prognostic factor for 30-d patient mortality.CONCLUSION Intraoperative measurement of blood flow after reperfusion appears to be a predictor of EAD;Moreover,HAF should be considered a predictor of 30-d patient mortality.Pablo Lozano Lominchar Maitane Igone Orue-Echebarria Lorena Martín Cristina Julia Lisbona María Magdalena Salcedo Luis Olmedilla Hemant Sharma Jose Manuel Asencio JoséAngel López-Baena 2019World Journal of Hepatology2019,11,9:4
2Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study显示文摘AIM: To determine the presence of Helicobacter species DNA in the liver of chronic hepatitis C (CHC) patients with and without cirrhosis as compared to controls, and to identify the bacterial species involved. METHODS: Seventy-nine consecutive patients (HBV and HIV negative) with a liver sample obtained after liver biopsy or hepatic resection were studied: 41 with CHC without cirrhosis, 12 with CHC and cirrhosis, and 26 controls (HCV negative). Polymerase chain reactions (PCRs) targeting Helicobacter 16S rDNA and species- specific were performed on DNA extracted from the liver. A gastric infection with H pylori was determined by serology and confirmed by 13C-urea breath test. RESULTS: Overall, Helicobacter 16S rDNA was found in 16 patients (20.2%). Although positive cases tended to be higher in CHC patients with cirrhosis (41.6%) than in those without cirrhosis (17.0%) or in controls (15.4%), the difference was not statistically significant (P =0.08). H pylori-like DNA was identified in 12 cases and H. pullorum DNA in 2, while 2 cases remained unidenti- fied. Gastric infection with H pylori was found in only 2 of these patients. CONCLUSION: Our results do not confirm the associ- ation of Helicobacter species DNA in the liver of CHC patients with advanced liver disease. The lack of correlation between positive H pylori serology and the presence of H pylori-like DNA in the liver may indicate the presence of a variant of this species.Laurent Castéra Anne Pedeboscq Marcia Rocha Brigitte Le Bail Corinne Asencio Victor de Lédinghen Pierre-Henri Bernard Christophe Laurent Marie-Edith Lafon Maylis Capdepont Patrice Couzigou Paulette Bioulac-Sage Charles Balabaud FrancisMégraud Armelle Ménard 2006World Journal of Gastroenterology2006,12,45:3
3“Small-for-flow” syndrome: Shifting the “size” paradigm显示文摘J.M. Asencio J. Vaquero L. Olmedilla J.L. García Sabrido 2013Medical Hypotheses2013,,5:2
4Construction of replicative and integrative plasmids for setting up the in vivo expression technology in Helicobacter pylori显示文摘ANGELINI F MENARD A ASENCIO C 2004Plasmid2004,51,2:1
5Anti-HIV activity of natural triterpenoids and hemisynthetic derivatives 2004 -2009 显示文摘Cassels B K Asencio M 2011Phytochem Rev2011,10,4:1
6Lactic acidosis associated with propofol during general anaesthesia for neurosurgery显示文摘Bordes J Meaudre E Asencio Y 2008Ann Fr Anesth Reanim2008,27,3:1
7The role of ubiquinone in Caenorhabditis elegans longevity显示文摘Rodriguez Aguilera J C Gavilan A Asencio C 2005Ageing Res Rev2005,4,:1
8Bedside percutaneous trache- ostomy: a prospective randomised comparison of PercuTwist versus Griggs' forceps dilational tracheostomy 显示文摘Montcriol A Bordes J Asencio Y 2011Anacsth Intensive Care2011,39,2:1
9Hepatic Lesions Observed in Hepatitis C Virus Transgenic Mice Infected by H elicobacter hepaticus显示文摘Emilie Roux‐Goglin Pierre Dubus Corinne Asencio Marthe‐Aline Jutand Jean Rosenbaum Francis Mégraud 2012Helicobacter2012,,1:1
10Hardness Enhancement and Corrosion Current of Multilayer Coatings Based on Titanium Nitride显示文摘Arturo Talledo Junior Asencios Karin Paucar Alcides Lopez Carsten Benndorf Rolando Nufiez Jan Petersen 2015材料科学与工程(中英文A版)2015,5,7:1
11Transanal endo- scopic surgery with conventional laparoscopy materials: is it fea- sible?显示文摘Asencio A F Uribe Q N Balciscueta C Z 2011Cir Esp2011,89,2:1
12Clinical and manometric results of endorectal advancement flaps for complex anal fistula显示文摘Natalia Uribe Monica Millán Miguel Minguez Cristina Ballester Francisco Asencio Vicente Sanchiz Pedro Esclapez Juan Ruiz Castillo 2007International Journal of Colorectal Disease2007,,3:1
13Maintenance of normothermia during burn surgery with an intravascular temperature control system:a non-randomised controlled trial显示文摘Prunet B Asencio Y Lacroix G et a1 2012Injury2012,43,5:1
14Lessons learned on long-term operation of MBBR for refinery wastewater treatment 显示文摘Cabral C Syron E Asencio R C 2009Proceedings of the Water Environment Federation2009,,15:1
15Total ankle ar- throplasty in France显示文摘Besse J L Colombier JA Asencio J 2010Orthop Traumatol Surg Res2010,96,3:1
16Evaluation of a clinical pathway of the inguinal hernia re- pair in a general surgery service显示文摘Carvajal - Balaguera J Gonz61ez -Solana I Mluez - Asencio M 2010Rev Calid Asist2010,25,5:1
17Iatrogenic post intubation tracheal rupture treated conservatively without intubation:a case report显示文摘Prunet B Lacroix G Asencio Y 2008Cases Journal2008,1,:1
18Noninvasive detection of elevated intracranial pressure using a portable uhrasound systmn 显示文摘Prunet B Asencio Y Lacroix G 2012Am J Emerg Med2012,30,6:1
19Is Helicobacter pylori a true microaerophile显示文摘Bury-Moné S Kaakoush NO Asencio C 2006Helicobacter2006,11,4:1
20Total ankle arthroplasty and coronal plane deformities显示文摘Trincat S Kouyoumdjian P Asencio G 0,,01:1
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