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| 1 | Genotype-dependent activation or repression of HBV enhancer Ⅱ by transcription factor COUP-TF1显示文摘AIM: To study the expression of HBV enhancer Ⅱ by transcription factor COUP-TF1. METHODS: In order to study the regulation of HBV variants in the vicinity of the NRRE we cloned luciferase constructs containing the HBV enhancer Ⅱ from variants and from HBV genotypes A and D and cotransfected them together with expression vectors for COUP-TF1 into HepG2 cells. RESULTS: Our fi ndings show that enhancer Ⅱ of HBV genotype A is also repressed by COUP-TF1. In contrast, two different enhancer Ⅱ constructs of HBV genotype D were activated by COUP-TF1. The activation was independent of the NRRE because a natural variant with a deletion of nt 1763-1770 was still activated by COUP- TF1. CONCLUSION: Regulation of transcription of the HBV genome seems to differ among HBV genomes derived from different genotypes. These differences in transcriptional control among HBV genotypes may be the molecular basis for differences in the clinical course among HBV genotypes. | Silke F Fischer Katja Schmidt Nicola Fiedler Dieter Glebe Christian Schüttler Jianguang Sun Wolfram H Gerlich Reinald Repp Stephan Schaefer | 2006 | World Journal of Gastroenterology2006，12，37： | 2 |
| 2 | Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease显示文摘 | Besler Christian Heinrich Kathrin Rohrer Lucia Doerries Carola Riwanto Meliana Shih Diana M Chroni Angeliki Yonekawa Keiko Stein Sokrates Schaefer Nicola Mueller Maja Akhmedov Alexander Daniil Georgios Manes Costantina Templin Christian Wys | 2011 | Journal of Clinical Investigation2011，，7： | 1 |
| 3 | Bleeding complications in pediatric ABO-incompatible kidney transplantation显示文摘 | Betti Schaefer Burkhard T?nshoff Jan Schmidt Mohammad Golriz Arianeb Mehrabi Petra Gombos Christian Morath Elke Wühl Franz Schaefer Claus Peter Schmitt | 2013 | Pediatric Nephrology2013，，2： | 1 |
| 4 | Statin-Induced Improvement of Endothelial Progenitor Cell Mobilization, Myocardial Neovascularization, Left Ventricular Function, and Survival After Experimental Myocardial Infarction Requires Endothelial Nitric Oxide Synthase显示文摘 | Ulf Landmesser Niels Engberding Ferdinand H. Bahlmann Arnd Schaefer Antje Wiencke Andre Heineke Stephan Spiekermann Denise Hilfiker-Kleiner Christian Templin Daniel Kotlarz Maja Mueller Martin Fuchs Burkhard Hornig Hermann Haller Helmut Drexler | 2004 | Circulation2004，，14： | 1 |
| 5 | Suppression of hepatitis B virus enhancer 1 and 2 by hepatitis C virus core protein显示文摘 | Christian G Schüttler Nicola Fiedler Katja Schmidt Reinald Repp Wolfram H Gerlich Stephan Schaefer | 2002 | Journal of Hepatology2002，，6： | 1 |
| 6 | Combined treatment of a spinal metastasis with radio frequency heat ablatin and vertebro- plasty显示文摘 | Oliver Schaefer Christian Lohrmann | 2003 | AJR2003，180，： | 1 |
| 7 | Increased tissue endothelin-1-like immunoreactivity in the internal mammary artery of patients with diabetes or hypercholesterolemia modulates the graft flow in the peri-operative period显示文摘 | Heike G?bel Christian Ihling Janine Dentz Hans E. Schaefer Andreas M. Zeiher Gustav Fraedrich | 1998 | European Journal of Cardio-Thoracic Surgery1998，，4： | 1 |
| 8 | Adherence and mental side effects during hepatitis C treatment with interferon alfa and ribavirin in psychiatric risk groups显示文摘 | Martin Schaefer Folkhard Schmidt Christian Folwaczny Reinhard Lorenz Gaby Martin Norbert Schindlbeck Walter Heldwein Michael Soyka Heinz Grunze August Koenig Klaus Loeschke | 2003 | Hepatology2003，，2： | 1 |
| 9 | Progress in large-area glass coating by hign-rate sputtering显示文摘 | Gunther Beister Eckhard Dietrich Christian Schaefer Michael Schere Joachim Szcyrbowki | 1995 | Surface and Coatings Technology1995，7677，： | 1 |
| 10 | Progress in Large-area Glass Coating by High-rate Sputtering 显示文摘 | Beister Gunther Eckhard Dietrich Christian Schaefer | 1995 | Surface and Coatings Technology1995，，7677： | 1 |
| 11 | 急性卒中影像学研究路径图Ⅱ显示文摘卒中影像学研究组(StrokeImagingResearchGroup,STIR)、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议,最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议(Stroke Treatment Academy Industry Roundtable,STAIR)期间举行。 | Max Wintermark Gregory W. Albers Joseph P. Broderick Andrew M. Demchuk Jochen B. Fiebach Jens Fiehler James C. Grotta Gary Houser Tudor G. Jovin Kennedy R. Lees Michael H. Lev David S. Liebeskind Marie Luby Keith W. Muir Mark W. Parsons Rudiger von Kummer Joanna M. Wardlaw Ona Wu Albert J. Yoo Andrei V. Alexandrov Jeffry R. Alger Richard I. Aviv Roland Bammer Jean-Claude Baron Fernando Calamante Bruce C.V. Campbell Trevor C. Carpenter Sφren Christensen William A. Copen Colin P. Derdeyn E. Clarke Haley Jr Pooja Khatri Kohsuke Kudo Maarten G. Lansberg Lawrence L. Latour Ting-Yim Lee Richard Leigh Weili Lin Patrick Lyden Grant Mair Bijoy IC Menon Patrik Michel Robert Mikulik Raul G. Nogueira Left φstergaard Salvador Pedraza Christian H. Riedel Howard A. Rowley Pina C. Sanelli Makoto Sasaki Jeffrey L. Saver Pamela W. Schaefer Peter D. Schellinger Georgios Tsivgoulis Lawrence R. Wechsler Philip M. White Greg Zaharchuk Osama O. Zaidat Stephen M. Davis Geoffrey A. Donnan Anthony J. Furlan Werner Hacke Dong-Wha Kang Chelsea Kidw ell Vincent N. Thijs Gotz Thomalla Steven J. Warach 严晓铭 刘牧 张晶晶 柯开富 | 2014 | 国际脑血管病杂志2014，22，2： | 0 |
| 12 | 新西兰全新世冰川高频变动不同于北半球气候变化模式显示文摘理解全新世南、北半球之间气候变化的时间及原因至今仍是气候科学的一大主要问题。本文讨论的是过去7000年里新西兰南阿尔卑斯山冰川进退的高分辨率”Be年代学,其中最近1000年里至少发生了5个冰川变动事件。全新世中期至晚期的冰进活动范围在缩小,该冰川活动模式和对应时期北半球冰川活动模式很不相同。这一发现表明区域驱动和(或)区域放大机制的重要性。我们认为西南太平洋大气环流的变化是导致新西兰全新世冰川高频进退活动的一个重要因素。 | Joerg M. Schaefer George H. Denton Michael Kaplan Aaron Putnam Robert C. Finkel David J. A. Barrell Bjom G. Andersen Roseanne Schwartz Andrew Mackintosh Trevor Chinn Christian Schlǔchter 张江勇(译) | 2009 | 海洋地质2009，，3： | 0 |
| 13 | 微电子机械系统的新制造工艺技术(英文)显示文摘随着微电子机械系统新应用的不断推出,使得特殊制造工艺技术得到空前的发展。在过去的10年里,汽车是微电子机械系统产品商业化的推动力。如今,我们进入了以消费品和信息技术的产品占很高份额的微电子机械系统生产制造的新时代,如微射流器件,微光电子机械系统,射频微电子机械系统,非汽车应用加速度器和陀螺等。阐述用于商业化的如上所述器件的新制造工艺技术,即用全自动轨道传送光刻系统来实现低成本的紫外线光刻工艺,以及用于加速度器和陀螺等消费品的高真空键合制造工艺技术。 | Paul Lindner Christian Schaefer Shari Farrens Viore Dragoi | 2004 | 电子工业专用设备2004，33，1： | 0 |
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