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| 1 | The Importance of Heparan Sulfate in Herpesvirus Infection显示文摘Herpes simplex virus type-1 (HSV-1) is one of many pathogens that use the cell surface glycosaminoglycan heparan sulfate as a receptor. Heparan sulfate is highly expressed on the surface and extracellular matrix of virtually all cell types making it an ideal receptor. Heparan sulfate interacts with HSV-1 envelope glycoproteins gB and gC during the initial attachment step during HSV-1 entry. In addition,a modified form of heparan sulfate,known as 3-O-sulfated heparan sulfate,interacts with HSV-1 gD to induce fusion between the viral envelope and host cell membrane. The 3-O-sulfation of heparan sulfate is a rare modification which occurs during the biosynthesis of heparan sulfate that is carried out by a family of enzymes known as 3-O-sulfotransferases. Due to its involvement in multiple steps of the infection process,heparan sulfate has been a prime target for the development of agents to inhibit HSV entry. Understanding how heparan sulfate functions during HSV-1 infection may not only be critical for inhibiting infection by this virus,but it may also be crucial in the fight against many other pathogens as well. | Christopher D. O'Donnell Deepak Shukla | 2008 | Virologica Sinica2008，23，6： | 3 |
| 2 | Metafrontier frameworks for the study of firm-level efficiencies and technology ratios显示文摘 | Christopher J. O’Donnell D. S. Prasada Rao George E. Battese | 2008 | Empirical Economics2008，，2： | 2 |
| 3 | A Metafrontier Production Function for Estimation of Technical Efficiencies and Technology Gaps for Firms Operating Under Different Technologies显示文摘 | George E. Battese D. S. Prasada Rao Christopher J. O’Donnell | 2004 | Journal of Productivity Analysis2004，，1： | 2 |
| 4 | Metafrontier frameworks for the study of firm-level efficiencies and technology ratios显示文摘 | Christopher J. O'Donnell D. S. Prasada Rao George E. Battese | 2008 | Empirical Economics2008，，2： | 2 |
| 5 | 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction显示文摘 | Patrick T. O’Gara Frederick G. Kushner Deborah D. Ascheim Donald E. Casey Mina K. Chung James A. de Lemos Steven M. Ettinger James C. Fang Francis M. Fesmire Barry A. Franklin Christopher B. Granger Harlan M. Krumholz Jane A. Linderbaum David A. Morrow L. | 2013 | Journal of the American College of Cardiology2013，，： | 1 |
| 6 | 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction显示文摘 | Patrick T. O’Gara Frederick G. Kushner Deborah D. Ascheim Donald E. Casey Mina K. Chung James A. de Lemos Steven M. Ettinger James C. Fang Francis M. Fesmire Barry A. Franklin Christopher B. Granger Harlan M. Krumholz Jane A. Linderbaum David A. Morrow L. | 2013 | Journal of the American College of Cardiology2013，，： | 1 |
| 7 | Endovascular management of iliac artery occlusions: extending treatment to TransAtlantic Inter-Society Consensus class C and D patients显示文摘 | Christopher D. Leville Vikram S. Kashyap Daniel G. Clair James F. Bena Sean P. Lyden Roy K. Greenberg Patrick J. O’Hara Timur P. Sarac Kenneth Ouriel | 2006 | Journal of Vascular Surgery2006，，1： | 1 |
| 8 | The pesticide adjuvant, Toximul?, alters hepatic metabolism through effects on downstream targets of PPARα显示文摘 | Jacqueline Upham Philip D. Acott Patrick O’Regan Christopher J. Sinal John F.S. Crocker Laurette Geldenhuys Mary G. Murphy | 2007 | BBA - Molecular Basis of Disease2007，，9： | 1 |
| 9 | Evaluation of viscoelastic poly(ethylene glycol) sols as vitreous substitutes in an experimental vitrectomy model in rabbits显示文摘 | Christopher D. Pritchard Sven Crafoord Sten Andréasson Karin M. Arnér Timothy M. O’Shea Robert Langer Fredrik K. Ghosh | 2010 | Acta Biomaterialia2010，，3： | 1 |
| 10 | Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma显示文摘 | Surasak Phuphanich Christopher J. Wheeler Jeremy D. Rudnick Mia Mazer HongQian Wang Miriam A. Nu?o Jaime E. Richardson Xuemo Fan Jianfei Ji Ray M. Chu James G. Bender Elma S. Hawkins Chirag G. Patil Keith L. Black John S. Yu | 2013 | Cancer Immunology, Immunotherapy2013，，： | 1 |
| 11 | A randomized, prospective, double-blinded evaluation of selective bowel decontamination in liver transplantation显示文摘 | Walter C. Hellinger Joseph D. Yao Salvador Alvarez Janis E. Blair John J. Cawley Carlos V. Paya Peter C. O’Brien James R. Spivey Rolland C. Dickson Denise M. Harnois David D. Douglas Christopher B. Hughes Justin H. Nguyen David C. Mulligan Jeffrey L. Stee | 2002 | Transplantation2002，，12： | 1 |
| 12 | The imaging spectrum of bronchopulmonary sequestration显示文摘 | Christopher M. Walker Carol C. Wu Matthew D. Gilman J. David Godwin Jo-Anne O Shepard Gerald F. Abbott | 2014 | Current Problems in Diagnostic Radiology2014，，： | 1 |
| 13 | Risk stratification after hospitalization for decompensated heart failure显示文摘 | G.Michael Felker Jeffrey D. Leimberger Robert M. Califf Michael S. Cuffe Barry M. Massie Kirkwood F. Adams Mihai Gheorghiade Christopher M. O’Connor | 2004 | Journal of Cardiac Failure2004，，： | 1 |
| 14 | ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 Appropriate Use Criteria for Cardiac Computed Tomography显示文摘 | Allen J. Taylor Manuel Cerqueira John McB. Hodgson Daniel Mark James Min Patrick O’Gara Geoffrey D. Rubin Christopher M. Kramer Allen J. Taylor Daniel Berman Alan Brown Farooq A. Chaudhry Ricardo C. Cury Milind Y. Desai Andrew J. Einstein Antoinette S. Go | 2010 | Journal of Cardiovascular Computed Tomography2010，，6： | 1 |
| 15 | A Metafrontier Production Function for Estimation of Technical Efficiencies and Technology Gaps for Firms Operating Under Different Technologies显示文摘 | George E. Battese D. S. Prasada Rao Christopher J. O’Donnell | 2004 | Journal of Productivity Analysis2004，，1： | 1 |
| 16 | Significance of Folate Receptor Alpha and Thymidylate Synthase Protein Expression in Patients with Non–Small-Cell Lung Cancer Treated with Pemetrexed显示文摘 | Daniel C. Christoph Bernadette Reyna Asuncion Biftu Hassan Cindy Tran Julia D. Maltzman Daniel J. O’Shannessy Murry W. Wynes Thomas C. Gauler Jeremias Wohlschlaeger Mathias Hoiczyk Martin Schuler Wilfried E. Eberhardt Fred R. Hirsch | 2013 | Journal of Thoracic Oncology2013，，1： | 1 |
| 17 | Risk stratification after hospitalization for decompensated heart failure显示文摘 | G.Michael Felker Jeffrey D. Leimberger Robert M. Califf Michael S. Cuffe Barry M. Massie Kirkwood F. Adams Mihai Gheorghiade Christopher M. O'Connor | 2004 | Journal of Cardiac Failure2004，，6： | 1 |
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