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| 1 | Isolation of the mucilages from Hibiscus rosasinensis linn.and Okra(Abelmoschus esculentus linn.) and studies of the binding effects of the mucilages显示文摘Objective:To isolate and evaluate comparatively the binding efficacy of the mucilages obtained from the plants of Hibiscus rosasinensis and Okra(Abelmoschus esculentus).Methods:Extraction of mucilages from the leaves of Hibiscus and pods of Okra(Ladies finger) was carried out by a cold maceration process.The extracted mucilages were subjected to various physicochemical properties for its suitability as an excipient in the formulation of tablet dosage form.Different concentrations(10,8,5,2 and 1%w/v) of binder solutions of Hibiscus and Okra were used for the formulation of tablets and the formulated tablets were evaluated by studying the standard parameters like diameter,thickness,weight variation,hardness,friability,disintegration and in vitro dissolution.Stability studies of the formulated tablets were conducted for four weeks. Results:The formulated tablets prepared using the mucilages of both Hibiscus and Okra had good appearance.The in vitro drug release profile of the tablets prepared using Okra mucilage had an optimum of 90%at a mucilage concentration of 1%w/v concentration mucilage itself within 4 h.Conclusions:According to the observations,the lower concentration levels of Okra can be used as an alternative binder to starch.The higher concentration levels of Okra mucilage show a slow and sustained release,and can be considered as an alternative natural excipient in the modified drug delivery systems.At the same time,the above natural excipient of Hibiscus mucilage could be used as a platform for prolonged release if its binder concentrations are increased. | Ameena K Dilip C Saraswathi R Krishnan PN Sankar C Simi SP | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 8 |
| 2 | Anti-inflammatory activity of the leaf extacts of Gendarussa vulgaris Nees显示文摘Objective:To evaluate the anti-inflammatory property of the leaf exacts of Gendarussa vulgaris(G.vulgarix) Nees.Methods:G.vulgarix Nees of the family Apocynaceae is a medium sized tree grown in semishade or no shade and is common in the Ernad and Nilambur taluks of Kerala. Various parts of this plant have been used in the treatment of ulcers,sores,inflammation, dyspepsia,healing of wounds,etc.The present study aimed at the evaluation of anti-inflammatory property of the aqueous and alcoholic extracts of the leaves by both in vitro and in vivo methods. In vitro method was estimated by human red blood cell membrane stabilisation(HRBC) method and in vivo method was estimated on the carrageenan induced paw oedima.Results:Both the methods showed significant anti-inflammatory property of the different extracts tested. Conclusions:The alcoholic extract at a concentration of 300 mg/mL showed potent activity on comparing with the standard drug diclofenac sodium. | TK Mohamed Saleem AK Azeem C Dilip C Sankar NV Prasanth R Duraisami | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，2： | 3 |
| 3 | Anti-inflammatory activity of the glandular extracts of Thunnus alalunga显示文摘Objective:To evaluate the anti-inflamattory activity of Thunnus alalunga by both in vitro and in vivo methods.Methods:Anti-inflammatory activity of the chloroform water extract of Thunnus alalunga was done by both in vitro and in vivo methods.In vitro method was done by human red blood cells membrane stabilization method(HRBC).In vivo evaluation was estimated on Wister albino rats.Acute toxicity studies were done on the extract and no toxicity was reported.Results: The percentage protection exhibited by 300 mg/mL concentration was more when compared to the other ones.The 400 mg/mL concentration showed potent activity on comparison with the standard during in vivo evaluation.Conclusions:In both means of estimation the extract of Thunnus alalunga was found to possess significant anti-inflammatory activity. | A.K.Azeem C Dilip S S Prasanth V Junise Hanan Shahima Kumsr Sajeev C.Naseera | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，10： | 3 |
| 4 | Antimicrobial activity of cotton and silk fabric with herbal extract by micro encapsulation显示文摘Objective:To explore the antimicrobial activity of microcapsules encapsulated with mixture of herbs like neem,tulsi and turmeric,and its application on cellulosic fabric in the form of microcapsules.Methods:The microcapsules were prepared from the mixture of herbs by plain diffusion method,a natural encapsulation technique with yeast and applied on cotton and silk fabric by pad-dry-cure method.The microcapsules were fixed on cotton and silk fabric using the binder UF Silpure FBR-5(PA)B at 120℃.The antimicrobial activities of the finished fabric were assessed by using three types of bacteria including Staphylococcus aureus,Escherichia coli and Pseudomonas.Results:The results of antimicrobial activity from the tests including parallel streak method and disc diffusion method showed that activity of the mixture of herbs was very effective among the three types of bacteria selected,and the antimicrobial activity of prepared microcapsule against Pseudomonas was very good.Conclusions:The herbal microcapsule treated fabric could be applied in the field of medicine.The scanning electron microscope photographs ensure the fixing of the microcapsules firmly in the yarn structure of plain woven cotton and silk fabric. | Saraswathi R Krishnan PN Dilip C | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，2： | 3 |
| 5 | Parallel Acquisition of PN Sequences in DS/SS System显示文摘 | Kapil K C Dilip V S | 1994 | IEEE TRANSACTIONS ON COMMUNICATIONS1994，42，5： | 1 |
| 6 | Quality design and environmental implications of green consumerism in remanufacturing显示文摘 | Wenjun Gu Dilip Chhajed Nicholas C Petruzzi | 2015 | Int J of Production Economics2015，162，4： | 1 |
| 7 | Major outer membrance proteins of Vibrio cholerae and the role in induction of pro- tective immunity through inhibition of intestinal colonization 显示文摘 | Dilip K S Tapas K S Asoke C G | 1992 | Infect Immun1992，60，11： | 1 |
| 8 | Optimal investment in derivative securities显示文摘 | Peter C Xing J Dilip B M | 2001 | Finance and Stochastics2001，5，： | 1 |
| 9 | Direct marketing,indirect profits:a strategic analysis of dual-channel supply-chain design显示文摘 | Wei-yu K C Dilip C James D H | 2003 | Management Science2003，49，1： | 1 |
| 10 | Technical Details of Sentinel Lymph Node Mapping in Colorectal Cancer and Its Impact on Staging显示文摘 | Sukamal Saha MD FRCS (C) David Wiese MD Julio Badin MD Thomas Beutler MD Dean Nora MD B. K. Ganatra MD Dilip Desai MD S. Kaushal MD M. Nagaraju MD Madan Arora MD Trevor Singh MD | 2000 | Annals of Surgical Oncology2000，，2： | 1 |
| 11 | Major outer membranee proteins of Vibrio eholerae and the role in induction of protective immunity through inhibition of intestinal colonization显示文摘 | DILIP K S TAPAS K S ASOKE C G | 1992 | Infect Immun1992，60，11： | 1 |
| 12 | Boron-doped Hydrogenated Amorphous Carbon Films Grown By Surface-wave Mode Microwave Plasma Chemical Vapor Deposition显示文摘 | Sudip Adhikari Dilip C Ghimire | 2006 | Diamond and Related Materials2006，，15： | 1 |
| 13 | The structure and conformation of a water-insoluble (1→3)-(1→6)-β-D-glucan from the fruiting bodies of Pleurotus florida显示文摘 | DILIP R SOUMITRA M INDRANIL C | 2008 | Carbohydrate Research2008，343，5： | 1 |
| 14 | Surgical management of biliary gallstone disease during pregnancy显示文摘 | Carlos A Cosenza Bahman Saffari Nicolas Jabbour Steven C Stain David Garry Dilip Parekh Robert R Selby | 1999 | The American Journal of Surgery1999，，6： | 1 |
| 15 | Isolation and structural elucidation of water-soluble polysac- charide of a wild edible mushroom, Termitomyces striatus显示文摘 | SOUMITRA M INDRANIL C DILIP R | 2006 | Carbohydrate Research2006，341，7： | 1 |
| 16 | Irrational drug use-a pilot prescription study from Calicut,Kerala显示文摘Objective:To describe the prescribing behavior of the physician in Kerala,and to describe types and number of medicine prescribed by doctors so as to rationalize the prescription writing habits of physician.Methods: A six month study was done to define the pattern of drug use in Medical college hospital,Calicut. The data and the other important aspects of study were collected by personal interview,questionnaires meant for doctors and prescription monitoring Performa for the patients issued by WHO. The findings of survey were critically analyzed.Results: The results indicated that majority of doctors prescribed on the basis of patient's history,patient's feed back report,drug availability,brand cost,quality of drug and ADRs. All the interviewed doctors looked upon the side effects. It was found that individual drugs were prescribed more than fixed dose combinations (85.6%). Out of these 71.5% were prescribed as branded and 28.5% as generic. The demographic data,like name,age,sex,disease diagnosis were available on all the patient health care cards and these constituted an essential part of the prescription particularly age and sex being an important in deciding the dose preference for patients. Socio economically most patients were found to be in the grade ⅡI (Population below poverty line). During the study of drug related parameters,doses were mentioned only in 80% of the prescription. But duration of the drug therapy was found to be only 30%.These indicated the irrational use of prescription. Branded drugs prescribed were found to be 71.5%,which showed a trend towards a good prescription habit. The results indicated the rational use of drug.Conclusion: The survey reveales that most of the doctors in Medical college hospital,Calicut are maintaining rational use of drugs and their prescription writing habits was found to be good. | Dilip C Saraswathi R Krishnan PN Vinod thomas Sanal dev Prasanth NV Subashpillai | 2009 | 海南医学院学报2009，15，12： | 1 |
| 17 | The variancegamma process and option pricing 显示文摘 | Madan Dilip B Peter P Carr Eric C Chang | 1998 | European Finance Review1998，，2： | 1 |
| 18 | Quantifying the effect of air quality control measures during the 2010 CommonwealthGames at Delhi, India 显示文摘 | Beig G Dilip M C Ghude S D | 2013 | Atmospheric Environment2013，80，： | 1 |
| 19 | The blue active queue management algorithms显示文摘 | FENG W C SHIN K G DILIP K D | 2002 | IEEE/ACM Transactions on Networking2002，10，4： | 1 |
| 20 | Isolation and structural elucidation of water-soluble polysaccharide of a wild edible mushroom,Termitomyces striatus显示文摘 | Soumitra M Indranil C Dilip R | | 0，，341： | 1 |
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