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| 1 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013，19，46： | 6 |
| 2 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 3 | Analysis of wax hydrocarbons in petroleum source rocks from the Damintun depression, eastern China,using high temperature gas chromatography 显示文摘 | Huang H P Steve R L Gordon D L | 2003 | Organic Geochemistry2003，34，： | 1 |
| 4 | Deciphering the biology of My cobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole S T Brosch R Parkhill J Gamier T Churcher C Harris D Gordon S V Eiglmeier K Gas S Barry C E Tekaia F Badcock K Basham D Brown D Chillingworth T Cormor R Davies R Devlin K FeltweU T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Kroghs A McLean J Moule S Murphy L Oliver K Osborne J Quail M A Rafandream M A Rogers J Rutter S Seeger K Skelton J Squaraes R Squares S Sulston J E Taylo K Whitehead S Barrell B G | 1998 | Nature1998，393，： | 1 |
| 5 | Literature-based discovery by lexical statistics 显示文摘 | LINDSAY R K GORDON M D | 1999 | Journal of American Society for Informa- tion Science1999，49，8： | 1 |
| 6 | Values of Mills' ratio of area to bounding ordinate and of the normal probability integral for large values of the argument显示文摘 | GORDON R D | 1941 | The Annals of Mathematical Statistics1941，，12： | 1 |
| 7 | Discretion and reputation in a model of monetary policy显示文摘 | Barro R J Gordon D R | 1983 | Journal of Monetary Economics1983，，12： | 1 |
| 8 | Resistance to cytotoxic drugs in DNA mismatch repair-detcient cells clin显示文摘 | Aebi S Fink D Gordon R | 1997 | Cancer Res1997，3，： | 1 |
| 9 | Rules discretion and reputation in a model of monetary policy显示文摘 | Barro R J Gordon D B | 1983 | Journal of Monetary Economics1983，，12： | 1 |
| 10 | A Theory of Labor Market Segmentation显示文摘 | Gordon D Edwards R Reich M | | 0，，02： | 1 |
| 11 | A positive theory of monetary policy in a national rate model显示文摘 | Barro R J Gordon D | 1983 | Journal of Monetary Economics1983，，19： | 1 |
| 12 | Relative impact of oxidative stress on the functional competence and genomic integrity of human spermatozoa显示文摘 | Aitken R J Gordon E Harkiss D | 1998 | Biol Reprod1998，59，5： | 1 |
| 13 | Primary aldosteronism-careful investigation is essential and rewarding显示文摘 | Stowasser M Gordon R D | 2004 | Molecular and Cellular Endocrinology2004，217，12： | 1 |
| 14 | Expenditure Competition显示文摘 | GORDON R H WILSON J D | 2003 | Journal of Public Economic Theory2003，，3： | 1 |
| 15 | Ecological and evolutionary forces shaping microbial diversity in the human intestine显示文摘 | Peterson D A Gordon J I | 2006 | Cell2006，124，： | 1 |
| 16 | Eukaryotic initiation factor 4D, the hypusine-containing protein, is conserved among eukaryotes 显示文摘 | Gordon E D Mora R Meredith S C | 1987 | J Biol Chem1987，262，16： | 1 |
| 17 | Performance of commercial laying hens fed various phosphorus levels, with and without supplemental phytase显示文摘 | GORDON R ROLAND S D | 1997 | Poultry Science1997，76，8： | 1 |
| 18 | Effect of recent revision to the geomagnetic reversal time scale on estimates of current plate motion显示文摘 | DeMETS C GORDON R G ARGUS D F | 1994 | Geophys Res Lett1994，21，： | 1 |
| 19 | Persistent anomalies of the extratropieal northern hemisphere wintertime eireulation: Geographieal distribution and regional persistenee eharaeteristies 显示文摘 | Dole R M N D Gordon | 1983 | Mon Wea Rev1983，111，： | 1 |
| 20 | Drying and rewetting effects on soil microbial community composition and nutrient leaching显示文摘 | Gordon H Philip M H Bardgett R D | 2008 | Soil Biology & Biochemistry2008，40，： | 1 |
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