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154篇 您的检索式:作者名="Hochedlinger"
    题名 作者 年代 出处 被引量
1Cross-regulation of the Nanog and Cdx2 promoters显示文摘在哺乳动物的胚胎,内部房间团(ICM ) 的分离和 trophectoderm (TE ) 的第一种房间命运选择,,被抄写因素, Oct4 和 Cdx2 的互相对抗的效果调整 pluripotency 因素, Nanog,是必要的指定 epiblast。我们分析了 Nanog 和 Cdx2 的倡导者,并且发现了这二个抄写因素同样相互地被调整。用有有条件的 TE 区别的一根胚胎的干细胞线,我们证明 Nanog overexpression 压制 TE 标记的 upregulation,当时 Nanog 击倒的 upregulates TE 标记的表示。我们推进 Nanog 和 Cdx2 绑在并且镇压的表演对方的倡导者。而 Nanog 大美人在 ICM 导致可检测的 Cdx2 表示,我们不管多么不观察胚囊开发的公开混乱,显示 Nanog 起到在 ICM 和 TE 的分离的 Oct4 的一个谄媚的作用。Lingyi Chen Akiko Yabuuchi Sarah Eminli Ayumu Takeuchi Chi-Wei Lu Konrad Hochedlinger George Q Daley 2009Cell Research2009,19,9:3
2Ectopic expression of Oct4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues显示文摘Hochedlinger K Yamada Y Beard C 2005Cell2005,121,3:1
3Ectopic expression of Oct-4 blocks progenitor-cel differentiation and causes dysplasia in epithelial tissues显示文摘Hochedlinger K Yamada Y Beard C 0,,03:1
4Epigenetic instability in ES cells and cloned mice显示文摘Humpherys D Eggan K Akutsu H Hochedlinger K Rideout WM 3rd Biniszkiewicz D 2001Science2001,293,5527:1
5Monoclonal mice generated by nuclear transfer frommature B and T donor cells显示文摘Hochedlinger K Jaenisch R 2002Nature2002,415,6875:1
6X-Chromosome inactivation in cloned mouse embryos 显示文摘Eggan K Akutsu H Hochedlinger K 2000Science2000,290,5496:1
7Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution显示文摘Nimet Maherali Rupa Sridharan Wei Xie Jochen Utikal Sarah Eminli Katrin Arnold Matthias Stadtfeld Robin Yachechko Jason Tchieu Rudolf Jaenisch Kathrin Plath Konrad Hochedlinger 2007Cell Stem Cell2007,,1:1
8Nuclear reprogramming and pluripotency显示文摘Hochedlinger K Jaenisch R 2006Nature2006,441,7097:1
9X-Chromosome inactivation in cloned mouse embryos显示文摘 Akutsu H Hochedlinger K 2000Science2000,290,5496:1
10When fibroblasts MET iPSCs显示文摘Polo J M Hochedlinger K 2010Cell Stem Cell2010,7,1:1
11Reprogramming of a melanoma genome by nuclear transplantation显示文摘Hochedlinger K Blelloch R Brennan C 2004Genes Dev2004,18,15:1
12ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable显示文摘Brambrink T Hochedlinger K Bell G 2006Proc Natl Acad Sci USA2006,103,:1
13Nuclear reprogramming and pluripotency 显示文摘Hochedlinger K Jaenisch R 2006Nature2006,441,7097:1
14Nuclear transplantation: Lessons from frogs and mice显示文摘Hochedlinger K Jaenisch R 2002Curr Opin Cell Biol2002,14,6:1
15Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues显示文摘Hochedlinger K Yamada Y Beard C 2005Cell2005,121,3:1
16Reprogramming of pancreatic β cells into induced pluripotent stem cells显示文摘Stadtfeld M Brennand K Hochedlinger K 2008Curr Biol2008,18,12:1
17The sox family of transcription factors:versatile regulators of stem and progenitor cell fate 显示文摘Sarkar A Hochedlinger K 2013Cell Stem Cell2013,12,1:1
18Monoclonal mice generated by nuclear transfer from mature B and T donor cells 显示文摘Hochedlinger K Jaenisch R 2002Nature2002,415,6875:1
19Guidelines and techniques for the generation of induced pluripotent stem cells显示文摘Maherali N Hochedlinger K 2008Cell Stem Cell2008,3,6:1
20Chromatin Connections to Pluripotency and Cellular Reprogramming显示文摘Stuart H. Orkin Konrad Hochedlinger 2011Cell2011,,6:1
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