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| 1 | Alcohol dehydrogenase: A potential new marker for diagnosis of intestinal ischemia using rat as a model显示文摘AIM: Intestinal ischemia (Ii) is an abdominal emergency due to blockade of the superior mesenteric artery resulting in 60-100% mortality if diagnosed late. Changes in several biochemical parameters such as D (-)-lactate, Creatinine kinase isoenzymes and lactate dehydrogenase suggested for early diagnosis, lack specificity and sensitivity. Therefore a biochemical parameter with greater sensitivity needs to be identified.METHODS: Wistar male rats were randomly assigned into two groups; control sham operated (n = 24) and ischemic test (n = 24) group. Superior mesenteric arterial occlusion was performed in the ischemic test group for 1 h. Alcohol dehydrogenase (ADH) was estimated in blood from portal vein, right ventricle of heart, dorsal aorta (DA) and inferior vena cava (IVC). The Serum glutamic acid pyruvate transaminase (SGPT) was also estimated in blood from portal vein and right ventricle of heart.RESULTS: A significant increase (P<0.001) in the levels of ADH in both portal blood as well as heart blood of the test group (232.72±99.45 EU and 250.85±95.14 EU, respectively)as compared to the control group (46.39±21.69 EU and 65.38±30.55 EU, respectively) were observed. Similarly,increased levels of ADH were observed in blood samples withdrawn from DA and IVC in test animals (319.52±80.14EU and 363.90±120.68 EU, respectively) as compared to the control group (67.68±63.22 EU and 72.50±58.45 EU,respectively). However, in test animals there was significant increase in SGPT in portal blood (P = 0.054) without much increase in heart blood.CONCLUSION: Significant increase in the levels of ADH in portal and heart blood within 1 h of SMA occlusion without increase in SGPT in heart blood, suggests that the origin of ADH is from ischemic intestine and not from liver. Similarly, raised ADH levels were found in DA and IVC as well. IVC blood does represent peripheral blood sample. A raised level of ADH in test animals confirms it to be a potential marker in the early diagnosis of Ii. | Upendra R Gumaste Mukund M Joshi Devendra T Mourya Pradip V Barde Ghanshyam K Shrivastav Vikram S Ghole | 2005 | World Journal of Gastroenterology2005，11，6： | 9 |
| 2 | RANKL/RANK control Brca1 mutation-driven mammary tumors显示文摘 | Verena Sig Kwadwo Owusu-Boaitey Puma A Joshi Anoop Kavirayani Gerald Wimsberger Maria Novatchkova Ivona Kozieradzki Daniel Schramek Nnamdi Edokobi Jerome Hersl Aishia Sampson Ashley Odai-Afotey Conxi Lazaro Eva Gonzalez-Suarez Miguel A Pujaaa for CIMBA Holger Heyn Enrique Vidal Jennifer Cru. ickshank Hal Berman Renu Sarao Melita Tieevic Iris Uribesalgo Luigi Tortola Shuan Rao Yen Tan Georg Pfeiler Eva YHP Lee Zsuzsanna Bago-Horvath Lukas Kenner Helmuth Popper Christian Singer Rama Khokha LaundeRe P Jones Josef M Penninger | 2016 | Cell Research2016，26，7： | 3 |
| 3 | Influence of experimental soil disturbances on the diversity of plants in agricultural grasslands显示文摘Aims and Methods Disturbance is supposed to play an important role for biodiversity and ecosystem stability as described by the intermediate disturbance hypoth-esis(IDH),which predicts highest species richness at intermediate levels of disturbances.In this study,we tested the effects of artificial soil distur-bances on diversity of annual and perennial vascular plants and bryo-phytes in a field experiment in 86 agricultural grasslands differing in land use in two regions of Germany.On each grassland,we implemented four treatments:three treatments differing in application time of soil dis-turbances and one control.One year after experimental disturbance,we recorded vegetation and measured biomass productivity and bare ground.We analysed the disturbance response taking effects of region and land-use-accompanied disturbance regimes into account.Important Findings Region and land-use type strongly determined plant species rich-ness.Experimental disturbances had small positive effects on the species richness of annuals,but none on perennials or bryophytes.Bare ground was positively related to species richness of bryophytes.However,exceeding the creation of 12%bare ground further distur-bance had a detrimental effect on bryophyte species richness,which corresponds to the IDH.As biomass productivity was unaffected by disturbance our results indicate that the disturbance effect on spe-cies richness of annuals was not due to decreased overall produc-tivity,but rather due to short-term lowered inter-and intraspecific competition at the newly created microsites.Generally,our results highlight the importance of soil disturbances for species richness of annual plants and bryophytes in agricultural grasslands.However,most grasslands were disturbed naturally or by land-use practices and our additional experimental soil dis-turbances only had a small short-term effect.Overall,total plant diversity in grasslands seemed to be more limited by the availabil-ity of propagules rather than by suitable microsites for germination.Thus,nature conservation efforts to increase grassland diversity should focus on overcoming propagule limitation,for instance by additional sowing of seeds,while the creation of additional open patches by disturbance might only be appropriate where natural disturbances are scarce. | Jörg Müller Johannes Heinze Jasmin Joshi Steffen Boch Valentin H.Klaus Markus Fischer Daniel Prati | 2014 | Journal of Plant Ecology2014，7，6： | 3 |
| 4 | Acinetobacter baumannii:An emerging pathogenic threat to public health显示文摘Over the last three decades, Acinetobacter has gained importance as a leading nosocomial pathogen, partly due to its impressive genetic capabilities to acquire resistance and partly due to high selective pressure, especially in critical care units. This low-virulence organism has turned into a multidrug resistant pathogen and now alarming healthcare providers worldwide. Acinetobacter baumanni(A. baumannii) is a major species, contributing about 80% of all Acinetobacter hospital-acquired infections. It disseminates antibiotic resistance by virtue of its extraordinary ability to accept or donate resistance plasmids. The procedures for breaking the route of transmission are still proper hand washing and personal hygiene(both the patient and the healthcare professional), reducing patient's biofilm burden from skin, and judicious use of antimicrobial agents. The increasing incidence of extended-spectrum beta-lactamases and carbapenemases in A. baumannii leaves almost no cure for these 'bad bugs'.To control hospital outbreaks of multidrug resistantAcinetobacter infection, we need to contain their dissemination or require new drugs or a rational combination therapy. The optimal treatment for multidrug-resistant A. baumannii infection has not been clearly established, and empirical therapy continues to require knowledge of susceptibility patterns of isolates from one's own institution. This review mainly focused on general features and introduction to A. baumannii and its epidemiological status, potential sources of infection, risk factors, and strategies to control infection to minimize spread. | Suresh G Joshi Geetanjali M Litake | 2013 | World Journal of Clinical Infectious Diseases2013，3，3： | 3 |
| 5 | Transfusion-transmitted virus in association with hepatitis A-E viral infections in various forms of liver diseases in India显示文摘瞄准:描述播送输送的病毒(TTV ) 的流行与在在诺思 India.METHODS 的肝疾病的不同形式的肝炎 A-E 病毒的感染联合的感染:从一个总数的血清 137 个病人数,包括 37 有尖锐病毒的肝炎( AVH )的病人,有长期的病毒的肝炎( CVH )的 37 个病人,有肝硬变的 31 个病人和有暴发性的肝的失败( FHF )的 32 个病人,为 TTV-DNA 和肝炎 A-E 病毒的标记两个都被分析。肝炎 B (HBV ) 的存在,丙肝病毒(HCV ) 和肝炎 E 病毒(HEV ) 感染在不同的组在不同比例被检测。而且, TTV-DNA 同时在 100 健康供血者 also.RESULTS 被测试:任何一个都没病人有肝炎 A 病毒(HAV ) 和肝炎 D 病毒(HDV ) 感染。TTV-DNA 的全面流行与 FHF 与 AVH,有 CVH 的 18.9% 盒子,有肝硬化的 48.4% 盒子和 9.4% 盒子在 27.1% 情况中被检测。同时在 100 健康供血者测试的 TTV-DNA 显示出 27% 确实。在与另外的肝炎建立在 TTV 感染之间的一种关系上病毒的感染, TTV 在这些疾病组与 HBV, HCV 和 HEV 表明了合作感染。有中高音的 TTV 的关联在重量的单位铺平一没在感染 TTV 的病人表明高中高音水平,建议那 TTV 不引起严重的肝 damage.CONCLUSION:TTV 感染在印度在病人和健康个人两个都是流行的。然而,它没与另外的肝炎有任何重要关联病毒的感染,它也不与肝疾病在病人生产严重的肝损坏的一条证据。 | M Irshad Y Sharma I Dhar J Singh YK Joshi | 2006 | World Journal of Gastroenterology2006，12，15： | 3 |
| 6 | Transfusion transmitted virus: A review on its molecular characteristics and role in medicine显示文摘现在的评论给输送的更新的概述播送病毒(TTV ) ,一个新奇代理人在与它的分子的特征的关系,流行病学的特征,传播的模式,组织向性,致病,在各种各样的疾病的角色和它从身体的根除。TTV,一个 DNA 病毒,一个单身者被搁浅,非包,有包括 3852 的一个小、 covalently 关上的圆形的染色体的长 DNA 病毒基于的 3.8 kb。它是尝试性地指明的 Circinoviridae 病毒。TTV 染色体顺序是异构的并且揭示六不同遗传型和几种子类型的存在。TTV 被报导了不仅经由非肠道的线路,而且经由交替的线路播送。这个病毒也在不同非人类的首领被检测了。目前, TTV 被聚合酶链反应(PCR ) 没有另外的可得到的诊断试金检测。它全球性显示出它的存在并且在健康的人的高百分比人口以及在各种各样的疾病组被检测。开始,它应当与肝疾病有强壮的协会;然而,几乎没有小证据在引起肝疾病显示出它的肝向性和贡献。它在牙齿过敏细胞溶解病人显示出高流行,向它在肾的疾病的意义指。另外, TTV 与几传染、非传染的疾病被联系。不过,它的准确致病是还没清楚的, TTV 病毒可能住并且在骨髓房间和外部血乘单音的原子房间(PBMC ) 。最近,被尝试了根除有干扰素治疗的这个病毒。更多的信息仍然被需要解脱与 TTV 有关的各种各样的谜。 | M Irshad YK Joshi Y Sharma I Dhar | 2006 | World Journal of Gastroenterology2006，12，32： | 3 |
| 7 | An Overview of the JPEG 2000 Still Image Compression Standard 显示文摘 | M Rabbani R Joshi | 2000 | Signal Processing: Image Communication2000，17，1： | 2 |
| 8 | Supplementation with flax oil and vitamin C improves the outcome of attention deficit hyperactivity disorder (ADHD) 显示文摘 | Joshi K Lad S Kale M | 2006 | Prostaglandins Leukot Essent Fatty Acids2006，74，1： | 1 |
| 9 | Noise Reduction for NMR FID Signal via Gabor Transform显示文摘 | S Joshi J M Morris | 1997 | IEEE Trans Biomedical Engineering1997，44，6： | 1 |
| 10 | A new species of Rhizoucor显示文摘 | Joshi M C | 1982 | Sydowia1982，35，： | 1 |
| 11 | Yield and quality of soymilk and tofu made from soybean genotypes grown at four locations显示文摘 | BHARDWAJ H L BHAGSARI A S JOSHI J M | 1999 | Crop Sci1999，39，： | 1 |
| 12 | Male breast carcinoma:an evaluation of prognostic factors contributing to a poorer out come显示文摘 | Joshi MG Lee AK Loda M | 1996 | Cancer1996，77，3： | 1 |
| 13 | Chitinase and chitobiase production during fermentation of genetically improved Serratia liquefaciens显示文摘 | JOSHI S KOZLOWSKI M RICHENS S | 1989 | Enzyme Microb Technol1989，11，： | 1 |
| 14 | Facile synthesis noval fluorine containning pyrazole based thiazole derivatives and evaluation of antimicrobial activity 显示文摘 | Desai N C Joshi K M Rajpara H V | 2012 | Journal of Fluorine Chemistry2012，142，： | 1 |
| 15 | UHF wind profiler observations of monsoon low level jet over Pune显示文摘 | JOSHI R R NARENDRA S DESHPANDE S M | 2006 | Indian Journal of Radio & Space physics2006，35，： | 1 |
| 16 | Admission hyper- glycemia is predictive of outcome in critically Ⅲ trauma patients 显示文摘 | Sung J Bochicchio G V Joshi M | 2005 | J Trauma2005，59，1： | 1 |
| 17 | Intravenous β-artemether formulation (ARM NLC) as a superior alternative to commercial artesunate formulation显示文摘 | Patil S Joshi M Pathak S | 2012 | J Antimicrob Che- mother2012，67，11： | 1 |
| 18 | Non-parametric mixture model based evolution of level sets and application to medical images显示文摘 | Joshi N Brady M | | 0，，01： | 1 |
| 19 | Harmonic coordinates for character articulation 显示文摘 | JOSHI P MEYER M DEROSE T et nl | 2007 | AGM Trans on Graphic2007，26，3： | 1 |
| 20 | Adaptive statefeedback and tracking control of systems withactuator failures显示文摘 | TAO G JOSHI S M Ma X | 2001 | IEEE Transactions on AutomaticControl2001，46，1： | 1 |
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