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| 1 | Epidemiology of perforated peptic ulcer:Age-and gender-adjusted analysis of incidence and mortality显示文摘AIM:To investigate the epidemiological trends in inci-dence and mortality of perforated peptic ulcer(PPU)in a well-defined Norwegian population. METHODS:A retrospective,population-based,single-center,consecutive cohort study of all patients diag-nosed with benign perforated peptic ulcer.Included were both gastric and duodenal ulcer patients admitted to Stavanger University Hospital between January 2001 and December 2010.Ulcers with a malignant neoplasia diagnosis,verified by histology after biopsy or resection,were excluded.Patients were identified from the hospitals administrative electronic database using pertinent ICD-9 and ICD-10 codes(K25.1,K25.2,K25.5, K25.6,K26.1,K26.2,K26.5,K26.6).Additional searches using appropriate codes for relevant laparoscopic and open surgical procedures(e.g.,JDA 60,JDA 61,JDH 70 and JDH 71)were performed to enable a complete identification of all patients.Patient demographics,presentation patterns and clinical data were retrieved from hospital records and surgical notes.Crude and adjusted incidence and mortality rates were estimated by using national population demographics data. RESULTS:In the study period,a total of 172 patients with PPU were identified.The adjusted incidence rate for the overall 10-year period was 6.5 per 100 000 per year(95%CI:5.6-7.6)and the adjusted mortality rate for the overall 10-year period was 1.1 per 100 000 per year(95%CI:0.7-1.6).A non-significant decline in ad-justed incidence rate from 9.7 to 5.6 occurred during the decade.The standardized mortality ratio for the whole study period was 5.7(95%CI:3.9-8.2),while the total 30-d mortality was 16.3%.No difference in in-cidence or mortality was found between genders.However,for patients≥60 years,the incidence increased over 10-fold,and mortality more than 50-fold,compared to younger ages.The admission rates outside office hours were high with almost two out of three(63%) admissions seen at evening/night time shifts and/or during weekends.The observed seasonal variations in admissions were not statistically significant. CONCLUSION:The adjusted incidence rate,seasonal distribution and mortality rate was stable.PPU fre-quently presents outside regular work-hours.Increase in incidence and mortality occurs with older age. | Kenneth Thorsen Jon Arne Sreide Jan Terje Kvaly Tom Glomsaker Kjetil Sreide | 2013 | World Journal of Gastroenterology2013，19，3： | 14 |
| 2 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 3 | The removal of heavy metals from aqueous solutions by sawdust adsorption — removal of lead and comparison of its adsorption with copper显示文摘 | Bin Yu Y Zhang Alka Shukla Shyam S Shukla Kenneth L Dorris | 2001 | Journal of Hazardous Materials2001，，1： | 2 |
| 4 | The Effects of Attitudinal and Demographic Factors on Intention to Buy Pirated CDs:The Case of Chinese Consumers显示文摘 | KENNETH K KWONG OLIVER H M YAU JENNY S Y LEE etc | 2003 | Journal of Business Ethics2003，47，： | 1 |
| 5 | Stress: metaplastic effects in the hippocampus 显示文摘 | Jeansok J K Kenneth S Y | 1998 | Trends in Neuroseienees1998，21，12： | 1 |
| 6 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 1 |
| 7 | Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial显示文摘 | Nancy Y Lee Qiang Zhang David G Pfister John Kim Adam S Garden James Mechalakos Kenneth Hu Quynh T Le A Dimitrios Colevas Bonnie S Glisson Anthony TC Chan K Kian Ang | 2012 | Lancet Oncology2012，，2： | 1 |
| 8 | extraction of sulfur from marine sediment and its determination by gas chromatography 显示文摘 | KENNETH Y C MOHSEN S | 1973 | Environ Science and Techlnology1973，7，10： | 1 |
| 9 | High-performance Human Resource Practices, Citizenship Behavior, and Organizational Performance : A Relational Perspective 显示文摘 | SUN L Y ARYEE S KENNETH S L | 2007 | Academy of Management Journal2007，50，3： | 1 |
| 10 | Platinum-based anticancer agents:innovarive design strategies and biological perspectives显示文摘 | HO Y P AU-YEUNG S C F KENNETH K W T | 2003 | Med Res Rev2003，23，5： | 1 |
| 11 | Modelling algal blooms using vector autoregressive model with exogenous variables and long memory filter 显示文摘 | Lui Gibert C S Li W K Leung Kenneth M Y | 2007 | Ecological Modelling2007，200，22： | 1 |
| 12 | Modeling algal blooms using vector autoregressive model with exogenous variables and long memory filter显示文摘 | GILBERT C S LUIA W K KENNETH M Y L | 2007 | Ecological Modeling2007，200，12： | 1 |
| 13 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 1 |
| 14 | The removal of heavy metal from aqueous solutions by sawdust adsorption — removal of copper显示文摘 | Bin Yu Y Zhang Alka Shukla Shyam S Shukla Kenneth L Dorris | 2000 | Journal of Hazardous Materials2000，，1： | 1 |
| 15 | Laparoscopic versus open liver resection for elderly patients with malignant liver tumors: A single‐center experience显示文摘 | Albert C Y Chan Ronnie T P Poon Tan To Cheung Kenneth S H Chok Wing Chiu Dai See Ching Chan Chung Mau Lo | 2014 | J Gastroenterol Hepatol2014，，6： | 1 |
| 16 | A neural -network approach to fault detection and diagnosis in industrial process 显示文摘 | MAKI Y KENNETH S LOPARO | 1997 | IEEE Transactions on Control Systems Technology1997，5，6： | 1 |
| 17 | Stress:metaplastic effects on the hippocampus显示文摘 | Jeansok J K Kenneth S Y | 1998 | Trends in Neunosciene1998，21，12： | 1 |
| 18 | Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial显示文摘 | Nancy Y Lee Qiang Zhang David G Pfister John Kim Adam S Garden James Mechalakos Kenneth Hu Quynh T Le A Dimitrios Colevas Bonnie S Glisson Anthony TC Chan K Kian Ang | 2012 | Lancet Oncology2012，，2： | 1 |
| 19 | Extranodal follicular dendritic cellSarcoma显示文摘 | Kenneth E Y Michael S W | 2008 | Arch PatholLab Med2008，132，10： | 1 |
| 20 | Catalase activity as apotential vital biomarker of fish intoxication by the herbicide aminotriazole显示文摘 | Olena Y V Olga I K Kenneth B S | 2011 | Pesticide Biochemistry and Physiology2011，101，： | 1 |
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