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| 1 | Cloning and functional characterization of Rht8,a“Green Revolution”replacement gene in wheat显示文摘Dear Editor,Wheat(Triticum aestivum)is a major staple crop in the world and provides~20%of the food calories for human consumption(Appels et al.,2018).During the 1960s and 1970s,the introduction of two semi-dwarfing genes Rht-B1b and Rht-D1b in wheat varieties strikingly improved lodging resistance and harvest index,and therefore substantially increased grain yield,resulting in the well-known'Green Revolution'(Peng et al.,1999).However,plants carrying Rht-B1b and Rht-D1b suffer from several drawbacks. | Hongchun Xiong Chunyun Zhou Meiyu Fu Huijun Guo Yongdun Xie Linshu Zhao Jiayu Gu Shirong Zhao Yuping Ding Yuting Li Jiazi Zhang Ke Wang Xuejun Li Luxiang Liu | 2022 | Molecular Plant2022，15，3： | 7 |
| 2 | Rumen microbiome structure and metabolites activity in dairy cows with clinical and subclinical mastitis显示文摘Background:Due to the high prevalence and complex etiology,bovine mastitis(BM)is one of the most important diseases to compromise dairy cow health and milk quality.The shift in milk compositions has been widely investigated during mastitis,but recent studies suggested that gastrointestinal microorganism also has a crucial effect on the inflammation of other peripheral tissues and organs,including the mammary gland.However,research focused on the variation of rumen inner-environment during mastitis is still limited.Therefore,the ruminal microbial profiles,metabolites,and milk compositions in cows with different udder health conditions were compared in the present study.Furthermore,the correlations between udder health status and ruminal conditions were investigated.Based on the somatic cell counts(SCC),California mastitis test(CMT)parameters and clinical symptoms of mastitis,60 lactating Holstein dairy cows with similar body conditions(excepted for the udder health condition)were randomly divided into 3 groups(n=20 per group)including the healthy(H)group,the subclinical mastitis(SM)group and the clinical mastitis(CM)group.Lactation performance and rumen fermentation parameters were recorded.And rumen microbiota and metabolites were also analyzed via 16S rRNA amplicon sequencing and untargeted metabolomics,respectively.Results:As the degree of mastitis increased,rumen lactic acid(LA)(P<0.01),acetate,propionate,butyrate,valerate(P<0.001),and total volatile fatty acids(TVFAs)(P<0.01)concentrations were significantly decreased.In the rumen of CM cows,the significantly increased bacteria related to intestinal and oral inflammation,such as Lachnospiraceae(FDR-adjusted P=0.039),Moraxella(FDR-adjusted P=0.011)and Neisseriaceae(FDR-adjusted P=0.036),etc.,were accompanied by a significant increase in 12-oxo-20-dihydroxy-leukotriene B4(FDR-adjusted P=5.97×10^(−9))and 10beta-hydroxy-6beta-isobutyrylfuranoeremophilane(FDR-adjusted P=3.88×10^(−10)).Meanwhile,in the rumen of SM cows,the Ruminiclostridium_9(FDR-adjusted P=0.042)and Enterorhabdus(FDR-adjusted P=0.043)were increased along with increasing methenamine(FDR-adjusted P=6.95×10^(−6)),5-hydroxymethyl-2-furancarboxaldehyde(5-HMF)(FDR-adjusted P=2.02×10^(−6))and 6-methoxymellein(FDR-adjusted P=2.57×10^(−5)).The short-chain fatty acids(SCFAs)-producing bacteria and probiotics in rumen,including Prevoterotoella_1(FDRadjusted P=0.045)and Bifidobacterium(FDR-adjusted P=0.035),etc.,were significantly reduced,with decreasing 2-phenylbutyric acid(2-PBA)(FDR-adjusted P=4.37×10^(−6)).Conclusion:The results indicated that there was a significant shift in the ruminal microflora and metabolites associated with inflammation and immune responses during CM.Moreover,in the rumen of cows affected by SM,the relative abundance of several opportunistic pathogens and the level of metabolites which could produce antibacterial compounds or had a competitive inhibitory effect were all increased. | Yue Wang Xuemei Nan Yiguang Zhao Linshu Jiang Mengling Wang Hui Wang Fan Zhang Fuguang Xue Dengke Hua Jun Liu Junhu Yao Benhai Xiong | 2021 | Journal of Animal Science and Biotechnology2021，12，3： | 6 |
| 3 | The Models of Granular System and Algebraic Quotient Space in Granular Computing显示文摘Granular computing(Gr C) is an emerging computing paradigm, and it is an umbrella term exploring multilevel granularity. we present a generic abstract mathematical model of the granular system. Supposing the inter-granule structure as an algebra, we propose the algebraic quotient space model. In this model, the granulation is based on a congruence relation and all the congruence relations on a granular system form a complete semi-order lattice, which is the theoretical basis for transformation,composition and decomposition among different granularities. The different granulation rules between the topological quotient space model and the algebraic quotient space model lead to the dissimilarity while composing granularities. A real-world case study is presented that demonstrates how the algebraic quotient space model works in the network transmission by error-correcting code. These work shows that the granular system model and the algebraic quotient space model are powerful conceptual modeling and functional specification methodologies for Gr C. | CHEN Linshu WANG Jiayang LI Li | 2016 | Chinese Journal of Electronics2016，25，6： | 6 |
| 4 | A New Granular Computing Model Based on Algebraic Structure显示文摘Granular computing is a very hot research field in computer science in recent years.This paper introduces a new granular computing model based on algebraic structure, in which the granule structure is assumed as a binary operator and the granulation is based on a congruence relation. Following the homomorphic consistency principle, the methods of granulation(granularity coarsening) and granularity combination(granularity refinement) are introduced, and the corresponding numerical examples show that these methods are efficient and applicable. These works have enriched the granular computing models from structure and provided theoretical basis for the combination of granular computing theory and algebraic theory. | CHEN Linshu WANG Jiayang WANG Weicheng LI Li | 2019 | Chinese Journal of Electronics2019，28，1： | 6 |
| 5 | Hyper Heuristic Approach for Design and Optimization of Satellite Launch Vehicle显示文摘Satellite launch vehicle lies at the cross-road of multiple challenging technologies and its design and optimization present a typical example of multidisciplinary design and optimization(MDO) process.The complexity of problem demands highly effi-cient and effective algorithm that can optimize the design.Hyper heuristic approach(HHA) based on meta-heuristics is applied to the optimization of air launched satellite launch vehicle(ASLV).A non-learning random function(NLRF) is proposed to con-trol low-level meta-heuristics(LLMHs) that increases certainty of global solution,an essential ingredient required in product conceptual design phase of aerospace systems.Comprehensive empirical study is performed to evaluate the performance advan-tages of proposed approach over popular non-gradient based optimization methods.Design of ASLV encompasses aerodynamics,propulsion,structure,stages layout,mass distribution,and trajectory modules connected by multidisciplinary feasible design approach.This approach formulates explicit system-level goals and then forwards the design optimization process entirely over to optimizer.This distinctive approach for launch vehicle system design relieves engineers from tedious,iterative task and en-ables them to improve their component level models.Mass is an impetus on vehicle performance and cost,and so it is considered as the core of vehicle design process.Therefore,gross launch mass is to be minimized in HHA. | Amer Farhan RAFIQUE HE Linshu Ali KAMRAN Qasim ZEESHAN | 2011 | Chinese Journal of Aeronautics2011，24，2： | 3 |
| 6 | Diurnal Variation of Soil CO2 Efflux and Its Optimal Measuring Time-window of Temperate Meadow Steppes in Western Songnen Plain, China显示文摘In order to study the diurnal variation of soil CO_2 efflux from temperate meadow steppes in Northeast China, and determine the best time for observation, a field experiment was conducted with a LI-6400 soil CO_2 flux system under five typical plant communities(Suaeda glauca(Sg), Chloris virgata(Cv), Puccinellia distans(Pd), Leymus chinensis(Lc) and Phragmites australis(Pa)) and an alkali-spot land(As) at the meadow steppe of western Songnen Plain. The results showed that the diurnal variation of soil CO_2 efflux exhibited a single peak curve in the growing season. Diurnal maximum soil respiration(Rs) often appeared between 11:00 and 13:00, while the minimum occurred at 21:00–23:00 or before dawn. Air temperature near the soil surface(Ta) and soil temperature at 10 cm depth(T10) exerted dominant control on the diurnal variations of soil respiration. The time-windows 7:00–9:00 could be used as the optimal measuring time to represent the daily mean soil CO_2 efflux at the Cv, Pd, Lc and Pa sites. The daily mean soil CO_2 efflux was close to the soil CO_2 efflux from 15:00 to 17:00 and the mean of 2 individual soil CO_2 efflux from 15:00 to 19:00 at the As and Sg sites, respectively. During nocturnal hours, negative soil CO_2 fluxes(CO_2 downwards into the soil) were frequently observed at the As and Sg sites, the magnitude of the negative CO_2 fluxes were 0.10–1.55 μmol/(m^2·s) and 0.10–0.69 μmol/(m^2·s)at the two sites. The results implied that alkaline soils could absorb CO_2 under natural condition, which might have significant implications to the global carbon budget accounting. | YU Xiuli LI Xiujun XU Linshu WANG Ming ZHANG Jitao JIANG Ming WANG Guodong | 2016 | Chinese Geographical Science2016，26，4： | 2 |
| 7 | Solid-state NMR study of metastable immiscibility in alkali borosilicate glasses显示文摘 | DU Linshu STEBBINS J F | 2003 | J Non-Cryst Solids2003，315，： | 1 |
| 8 | Modified pectin-based carrier for gene delivery:Cellular barriers in gene delivery course显示文摘 | Tali Katav LinShu Liu Tamar Traitel | 2008 | Journal of Controlled Release2008，130，： | 1 |
| 9 | 19F/23Na double reso- nance MAS NMR study of oxygen/fluorine ordering in the oxyfluoride NasW309F5 显示文摘 | Linshu D Ago S Tilt T | 2000 | Chem Mater2000，12，12： | 1 |
| 10 | Pectin-based systems for colon-specific drug delivery via oral route显示文摘 | Linshu Liu Marshall L Fishman | 2003 | Biomaterials2003，24，： | 1 |
| 11 | Neutron diffraction study of the nitride YTi Fe11 Nx显示文摘 | XIAODONG ZHANG LINSHU KONG et a1 | 1991 | Solid State Communications1991，78，： | 1 |
| 12 | Searching algorithm based on node ability automatically fitting in P2P network 显示文摘 | CHEN Linshu LIU Yuanhui | 2009 | Journal of Hunan University of Science&Technology:Nat- ural Science Edition2009，24，2： | 1 |
| 13 | Gelatin-pectin composite films from polyion-complex hydrogels 显示文摘 | Stefano Farris Karen M Schaich Liu Linshu | 2011 | Food Hydrocolloids2011，25，1： | 1 |
| 14 | Pectin-based systems for colon-specific drug delivery via oral route显示文摘 | Liu Linshu Marshall L Fishman Joseph Kost | 2003 | Biomaterials2003，24，19： | 1 |
| 15 | Reinforcing and toughening effects of bamboo pulp fiber on poly (3-hydroxybutyrate-co-3-hydroxyvaIerate) fiber composites 显示文摘 | Jiang Long Chen Feng Qian Jun Huang Jijun Wolcott M Liu Linshu Zhang Jinwen | 2009 | Industrial & Engineering Chemistry Research2009，49，2： | 1 |
| 16 | The effect of hepatitis B virus infected embryos on pregnancy outcome显示文摘 | Feng Ye Yi Liu Yan Jin Juanzi Shi Xueliang Yang Xiaojing Liu Xi Zhang Shumei Lin Ying Kong Linshu Zhang | 2014 | European Journal of Obstetrics and Gynecology2014，，： | 1 |
| 17 | Development of polyion-complex hydrogels as an alternative approach for the production of bio-based polymers for food packaging applications: a review显示文摘 | Stefano Farris Karen M. Schaich LinShu Liu Luciano Piergiovanni Kit L. Yam | 2009 | Trends in Food Science & Technology2009，，8： | 1 |
| 18 | An osteoconductive collagen/hyaluronate matrix for bone regeneration 显示文摘 | Liu Linshu Thompson AY Heidaran MA | 1999 | Biomaterials1999，20，12： | 1 |
| 19 | Effects of bar length on switching field of nanoscale nickel and cobalt bars fabricated using lithography显示文摘 | LINSHU KONG STEPHEN Y CHOU | 1996 | Journal of Applied Physics1996，80，： | 1 |
| 20 | Composite films from pectin and fish skin gelatin or soybean flour protein显示文摘 | Liu Linshu Liu Chengkung Marshall L Fishman | 2007 | J Agric Food Chem2007，55，： | 1 |
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