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| 1 | Seasonal variation in surface ozone and its regional characteristics at global atmosphere watch stations in China显示文摘We investigated the seasonal and spatial ozone variations in China by using three-year surface ozone observation data from the six Chinese Global Atmosphere Watch(GAW)stations and tropospheric column ozone data from satellite retrieval over the period2010–2012. It is shown that the seasonal ozone variations at these GAW stations are rather different, particularly between the western and eastern locations. Compared with western China, eastern China has lower background ozone levels. However, the Asian summer monsoon(ASM) can transport photochemical pollutants from the southern to the northern areas in eastern China, leading to a northward gradual enhancement of background ozone levels at the eastern GAW stations. Over China, the tropospheric column ozone densities peak during spring and summer in the areas that are directly and/or indirectly affected by the ASM, and the peak time lags from the south to the north in eastern China. We also investigated the regional representativeness of seasonal variations of ozone at the six Chinese GAW stations using the yearly maximum tropospheric column month as indicator.The results show that the seasonal variation characteristics of ozone revealed by the Chinese GAW stations are typical, with each station having a considerable large surrounding area with the ozone maximum occurring at the same month. Ozone variations at the GAW stations are influenced by many complex factors and their regional representativeness needs to be investigated further in a broader sense. | Ningwei Liu Weili Lin Jianzhong Ma Wanyun Xu Xiaobin Xu | 2019 | Journal of Environmental Sciences2019，31，3： | 23 |
| 2 | Consensus on the application of negative pressure wound therapy of diabetic foot wounds显示文摘Because China is becoming an aging society,the incidence of diabetes and diabetic foot have been increasing.Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates.Negative pressure wound therapy(NPWT)is one of the most effective techniques for the treatment of diabetic foot wounds and great progress,both in terms of research and its clinical application,has been made in the last 20 years of its development.However,due to the complex pathogenesis and management of diabetic foot,irregular application of NPWT often leads to complications,such as infection,bleeding and necrosis,that seriously affect its treatment outcomes.In 2020,under the leadership of Burns,Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association,the writing group for‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’was established with the participation of scholars from the specialized areas of burns,endocrinology,vascular surgery,orthopedics and wound repair.Drawing on evidence-based practice suggested by the latest clinical research,this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic foot.The consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot. | Shizhao Ji Xiaobin Liu Jie Huang Junmin Bao Zhaohong Chen Chunmao Han Daifeng Hao Jingsong Hong Dahai Hu Yufeng Jiang Shang Ju Hongye Li Zongyu Li Guangping Liang Yan Liu Gaoxing Luo Guozhong Lv Xingwu Ran Zhongmin Shi Juyu Tang Aiping Wang Guangyi Wang Jiangning Wang Xin Wang Bing Wen Jun Wu Hailin Xu Maojin Xu Xiaofei Ye Liangxi Yuan Yi Zhang Shichu Xiao Zhaofan Xia | 2021 | Burns & Trauma2021，9，1： | 17 |
| 3 | Characteristics and recent trends of sulfur dioxide at urban,rural,and background sites in North China:Effectiveness of control measures显示文摘SO 2 measurements made in recent years at sites in Beijing and its surrounding areas are performed to study the variations and trends of surface SO 2 at different types of sites in Northern China.The overall average concentrations of SO 2 are (16.8±13.1) ppb,(14.8±9.4) ppb,and (7.5±4.0) ppb at China Meteorological Administration (CMA,Beijing urban area),Gucheng (GCH,relatively polluted rural area,110 km to the southwest of Beijing urban area),and Shangdianzi (SDZ,clean background area,100 km to the northeast of Beijing urban area),respectively.The SO 2 levels in winter (heating season) are 4-6 folds higher than those in summer.There are highly significant correlations among the daily means of SO 2 at different sites,indicating regional characteristics of SO 2 pollution.Diurnal patterns of surface SO 2 at all sites have a common feature with a daytime peak,which is probably caused by the downward mixing and/or the advection transport of SO 2 -richer air over the North China Plain.The concentrations of SO 2 at CMA and GCH show highly significant downward trends (-4.4 ppb/yr for CMA and -2.4 ppb/yr for GCH),while a less significant trend (-0.3 ppb/yr) is identified in the data from SDZ,reflecting the character of SDZ as a regional atmospheric background site in North China.The SO 2 concentrations of all three sites show a significant decrease from period before to after the control measures for the 2008 Olympic Games,suggesting that the SO 2 pollution control has long-term effectiveness and benefits.In the post-Olympics period,the mean concentrations of SO 2 at CMA,GCH,and SDZ are (14.3±11.0) ppb,(12.1±7.7) ppb,and (7.5±4.0) ppb,respectively,with reductions of 26%,36%,and 13%,respectively,compared to the levels before.Detailed analysis shows that the differences of temperature,relative humidity,wind speed,and wind direction were not the dominant factors for the significant differences of SO 2 between the pre-Olympics and post-Olympics periods.By extracting the data being more representative of local or regional characteristics,a reduction of up to 40% for SO 2 in polluted areas and a reduction of 20% for regional SO 2 are obtained for the effect of control measures implemented for the Olympic Games. | Weili Lin Xiaobin XU Zhiqiang Ma Huarong Zhao Xiwen Liu Ying Wang | 2012 | Journal of Environmental Sciences2012，24，1： | 15 |
| 4 | Ammonium removal pathways and microbial community in GAC-sand dual media filter in drinking water treatment显示文摘A GAC-sand dual media filter(GSF) was devised as an alternative solution for drinking water treatment plant to tackle the raw water polluted by ammonium in place of expensive ozone-GAC processes or bio-pretreatments.The ammonium removal pathways and microbial community in the GSFs were investigated.The concentrations of ammonium,nitrite and nitrate nitrogen were monitored along the filter.Total inorganic nitrogen(TIN) loss occurred during the filtration.For 1 mg ammonium removal,the TIN loss was as high as 0.35 mg,DO consumption was 3.06 mg,and alkalinity consumption was 5.55 mg.It was assumed that both nitrification and denitrification processes occur in the filters to fit the TIN loss and low DO consumption.During the filtration,nitritation,nitrification and nitritation-anaerobic ammonium oxidation processes probably occur,while traditional nitrification and denitrification and simultaneous nitrification and denitrification processes may occur.In the GSFs,Nitrosomonas and Nitrospira are likely to be involved in nitrification processes,while Novosphingobium,Comamonadaceae and Oxalobacteraceae may be involved in denitrification processes. | Shuo Feng Shuguang Xie Xiaojian Zhang Zhiyu Yang Wei Ding Xiaobin Liao Yuanyuan Liu Chao Chen | 2012 | Journal of Environmental Sciences2012，24，9： | 14 |
| 5 | Non-uniform sediment incipient velocity显示文摘Based on the mechanism of non-uniform sediment incipient motion, the dragging force and uplift force coefficient expressions are put forward for the non-uniform bed material exposure and close alignment state. The incipient velocity formula of the non-uniform sediment is then established. It is shown that the formula structure is reasonable, and fine particles of the non-uniform sediment are more difficult to set into motion than the same sized uniform particles, whereas coarser particles are easier to set into motion than their uniform equivalents. The validity of the formula is verified by field and experiment data. | Haitao XU Jinyou LU Xiaobin LIU | 2008 | International Journal of Sediment Research2008，23，1： | 14 |
| 6 | High-speed colour-converting photodetector with all-inorganic CsPbBr_(3) perovskite nanocrystals for ultraviolet light communication显示文摘Optical wireless communication(OWC)using the ultra-broad spectrum of the visible-to-ultraviolet(UV)wavelength region remains a vital field of research for mitigating the saturated bandwidth of radio-frequency(RF)communication.However,the lack of an efficient UV photodetection methodology hinders the development of UV-based communication.The key technological impediment is related to the low UV-photon absorption in existing silicon photodetectors,which offer low-cost and mature platforms.To address this technology gap,we report a hybrid Sibased photodetection scheme by incorporating CsPbBr_(3) perovskite nanocrystals(NCs)with a high photoluminescence quantum yield(PLQY)and a fast photoluminescence(PL)decay time as a UV-to-visible colourconverting layer for high-speed solar-blind UV communication.The facile formation of drop-cast CsPbBr_(3) perovskite NCs leads to a high PLQY of up to ~73% and strong absorption in the UV region.With the addition of the NC layer,a nearly threefold improvement in the responsivity and an increase of ~25% in the external quantum efficiency(EQE)of the solar-blind region compared to a commercial silicon-based photodetector were observed.Moreover,timeresolved photoluminescence measurements demonstrated a decay time of 4.5 ns under a 372-nm UV excitation source,thus elucidating the potential of this layer as a fast colour-converting layer.A high data rate of up to 34 Mbps in solar-blind communication was achieved using the hybrid CsPbBr_(3)-silicon photodetection scheme in conjunction with a 278-nm UVC light-emitting diode(LED).These findings demonstrate the feasibility of an integrated high-speed photoreceiver design of a composition-tuneable perovskite-based phosphor and a low-cost silicon-based photodetector for UV communication. | Chun Hong Kang Ibrahim Dursun Guangyu Liu Lutfan Sinatra Xiaobin Sun Meiwei Kong Jun Pan Partha Maity Ee-Ning Ooi Tien Khee Ng Omar F.Mohammed Osman M.Bakr Boon S.Ooi | 2019 | Light(Science & Applications)2019，8，1： | 14 |
| 7 | BMP2 and VEGF promote angiogenesis but retard terminal differentiation of osteoblasts in bone regeneration by up-regulating Idl显示文摘不适当的 vascularization 限制骨头缺点的修理。以便改进 angiogenesis 并且加速成骨,有在骨头新生的基因修正的 co 有教养的房间的协同在这研究被调查。Endothelial 祖先房间(EPC ) 和骨头髓干细胞(BMSC ) 是有脉管的 endothelial 生长因素(VEGF ) 和骨头的基因的 transfected 形态基因的蛋白质 2 (BMP2 ) 由侵入人体气管粘膜的病菌分别地。co 有教养的房间,包括 BMSC + EPC, Ad-BMP2BMSC + EPC, BMSC + Ad-VEGFEPC,和 Ad-BMP2BMSC + 指定 Ad-VEGFEPC 组织为四个组,在 alginate 胶化上被播种然后肌内地植入进老鼠在 angiogenesis 和成骨上评估效果。VEGF 和 BMP2 能导致禁止者的 overexpression DNA 有约束力 1 (Id1 ) 显著地在 vitro 和增加支持了试管形成的基因在在培植以后的 Ad-BMP2BMSC + Ad-VEGFEPC 组的血容器的数量。不过, Id1 的 overexpression 延迟了造骨细胞和骨头形成的终端区别。后来,在 transcriptional 水平,钙小瘤,和碱的磷酸酶(高山) 活动的 osteogenic 基因表示证明渐渐的减少和最新形成的成骨区域的数量在 Ad-BMP2BMSC + Ad-VEGFEPC 组展出了小增加。这发现建议在 VEGFEPC 和 BMP2BMSCs 的 Id1 表示的一条平衡规定可能对为骨头新生的基于房间、基于基因的途径批评。 | Xiaobin Song Shaohua Liu Xun Qu Yingwei Hu Xiaoying Zhang Tao Wang Fengcai Wei | 2011 | Acta Biochimica et Biophysica Sinica2011，43，10： | 13 |
| 8 | Elevated expression of mature miR-21 and miR-155 in cancerous gastric tissues from Chinese patients with gastric cancer显示文摘Objective:MicroRNA (miRNA) expression is deregulated in many types of human cancers.We sought to investigate the expression patterns of the miRNAs,miR-21,miR-145 and miR-155 in sporadic gastric cancer in a Chinese population.Methods:Total RNA was extracted from archived gastric cancer tissues and adjacent non-cancerous tissues from 20 pairs of paraffin-embedded specimens.Expression levels of miR-21,miR- 145 and miR-155 were detected by quantitative reverse transcriptase PCR using a specific stem-loop primer,with U6 as the internal reference gene.Results:The expression of miR-21 and miR-155 in gastric cancer samples was significantly higher than in paired non-cancerous samples(P<0.05).There was no statistically significant difference in expression levels of miR-145 between cancerous and non-cancerous tissues(P>0.05).Conclusion:In Chinese sporadic gastric cancer tissues,the expressions of the oncogenic miR-21 and miR-155 were significantly up-regulated,while the expression of the tumor suppressor miR-145 was decreased,although this decrease was not statistically significant.Thus there is specificity in the miRNA expression pattern in gastric cancers in the Chinese population. | Li Liu Qi Chen Rensheng Lai Xiaobin Wu Xiaoyu Wu Fukun Liu Guohua Xu Yong Ji | 2010 | The Journal of Biomedical Research2010，24，3： | 11 |
| 9 | New progress and future prospects of CBM exploration and development in China显示文摘Efforts to speed up China's coal bed methane (CBM) exploration developments related to production safety, optimization of energy structures, prevention of energy waste and reduction of greenhouse gas emissions are all of great significance. In order to strengthen CBM exploration and development in China and to encourage increased growth in the CBM industry, we firstly give a general overview of the recent technological innovations and other developments in CBM exploration in the U.S., Canada and other countries. Using this background information as the starting point, we further present observations and analyses of CBM exploration and development, preferential policies, technical support and implications of R&D for CBM development in China. The results show that the problems related to CBM exploration technology development and lack of a complete set of management policies are still the major issues slowing down the growth of domestic CBM industry. Development of resource exploration and technology, R&D and establishment of favorable government policy to support the industry and the creation of a relevant information platform, etc. are finally recommended. | Vun Jian Xu Fengyin Liu Lin Zhong Ningning Wu Xiaobin | 2012 | International Journal of Mining Science and Technology2012，22，3： | 11 |
| 10 | Optimization design and analysis of Si-^(63)Ni betavoltaic battery显示文摘Among the various micro-powers being investigated, betavoltaic batteries are very attractive for numerous applications because of their advantages of high energy density, long life, strong anti-interference, and so on. Based on the basic principle of the betavoltaic effect, the current paper adopted the Monte Carlo N-Particle code to simulate the transport processes of β particles in semiconductor materials and to establish the calculation formulas for nuclear radiation-generated current, open circuit voltage, and so on. By discussing the effect of minority carrier diffusion length, doping concentration, and junction depth on the property of batteries, the present work concluded that the best parameters for batteries are the use of silicon and the radioisotope Ni-63, i.e., Ni-63 with a mass thickness of 1 mg/cm2, Na=1×1019 cm-3, Nd=3.16×1016 cm-3, junction area of 1 cm2, junction depth of 0.3 μm, and so on. Under these parameters the short-circuit current, open circuit voltage, output power, and conversion efficiency are 573.3 nA, 0.253 V, 99.85 nW, and 4.94%, respectively. Such parameters are valuable for micro-power fields, such as micro-electromechanical systems and pacemakers, among others. | TANG XiaoBin DING Ding LIU YunPeng CHEN Da | 2012 | Science China(Technological Sciences)2012，55，4： | 11 |
| 11 | Pressure balance and imbalance in the optic nerve chamber: The Beijing Intracranial and Intraocular Pressure (iCOP) Study显示文摘To determine the interdependence of intracranial pressure(ICP) and intraocular pressure(IOP) and how it affects optic nerve pressures, eight normal dogs were examined using pressure-sensing probes implanted into the left ventricle, lumbar cistern, optic nerve subarachnoid space in the left eye, and anterior chamber in the left eye. This allowed ICP, lumbar cistern pressure(LCP), optic nerve subarachnoid space pressure(ONSP) and IOP to be simultaneously recorded. After establishing baseline pressure levels, pressure changes that resulted from lowering ICP(via shunting cerebrospinal fluid(CSF) from the ventricle) were recorded. At baseline, all examined pressures were different(ICP>LCP>ONSP), but correlated(P<0.001). As ICP was lowered during CSF shunting, IOP also dropped in a parallel time course so that the trans-lamina cribrosa gradient(TLPG) remained stable(ICP-IOP dependent zone). However, once ICP fell below a critical breakpoint, ICP and IOP became uncoupled and TLPG changed as ICP declined(ICP-IOP independent zone). The optic nerve pressure gradient(ONPG) and trans-optic nerve pressure gradient(TOPG) increased linearly as ICP decreased through both the ICP-IOP dependent and independent zones. We conclude that ICP and IOP are coupled in a specific pressure range, but when ICP drops below a critical point, IOP and ICP become uncoupled and TLPG increases. When ICP drops, a rise in the ONPG and TOPG creates more pressure and reduces CSF flow around the optic nerve. This change may play a role in the development and progression of various ophthalmic and neurological diseases, including glaucoma. | Ruowu Hou Zheng Zhang Diya Yang Huaizhou Wang Weiwei Chen Zhen Li Jinghong Sang Sumeng Liu Yiwen Cao Xiaobin Xie Ruojing Ren Yazhuo Zhang Bernhard A. Sabel Ningli Wang | 2016 | Science China(Life Sciences)2016，59，5： | 11 |
| 12 | Laser Ablation ICP-MS U-Pb Zircon Geochronology of Granitoids and Quartz Veins in the Shihu Gold Mine, Taihang Orogen, North China: Timing of Gold-mineralization and Tectonic Implications显示文摘The Shihu gold deposit, situated in the Taihang Mesozoic orogen of the North China Craton (NCC), is hosted by ductile-brittle faults within Archean metamorphic core complex. The deposit is characterized by gold-bearing quartz-polymetallic sulfides veins. The Mapeng granitoids stock and intermediate-basic dikes intruded the metamorphic basement rocks, and are spatially related to gold mineralization. Detailed laser ablation inductively coupled plasma mass spectrometry (LA ICP-MS) U- Pb zircon ages of the granitic rocks, dykes and mineralized quartz veins in the studied area reveal its magmatic and mineralized history. The mineralized quartz veins contain inherited zircons with ages of about 2.55 Ga and 1.84 Ga, probably coming from the basement. These two Precambrian events are coeval with those in other parts of the NCC. The Mapeng granitoid stock, the largest intrusion in the area, was emplaced at ca. 130 Ma, and is coeval with magmatic zircon populations from diorites and quartz diorite pophyrites in the same region. The ca. 130 Ma magmatism and gold mineralization were most likely related to an underplating event that took place in the Taihang orogen at Late Mesozoic. The timing of gold mineralization with respect to felsic magmatism in the area is similar to those observed in other major gold-producing provinces in the NCC. This episode is simultaneous with those in the eastern margin of NCC, indicative of a widespread late Yanshanian metallogenic event that was a response to the Early Cretaceous lithosphere in the eastern NCC, in which the mesothermal gold deposits were formed from similar tectono-magmatic environments. | CAO Ye LI Shengrong XIONG Xianxiao LI Zhenzhen LIU Xiaobin YAO Meijuan ZHANG Huafeng | 2012 | Acta Geologica Sinica(English Edition)2012，86，5： | 8 |
| 13 | Fault Diagnosis Based on the Updating Strategy of Interval-Valued Belief Structures显示文摘This paper presents the dynamic method for fault diagnosis based on the updating of Interval-valued belief structures(IBSs). The classical Jeffrey's updating rule and the linear updating rule are extended to the framework of IBSs. Both of them are recursively used to generate global diagnosis evidence with the form of Interval basic belief assignment(IBBA) by updating the previous evidence with the incoming evidence. The diagnosis decision can be made by global diagnosis evidence. In the process of evidence updating, the similarity factors of evidence are used to determine switching between the extended Jeffrey's and linear updating rules, and to calculate the linear combination weights. The diagnosis examples of machine rotor show that the proposed method can provide more reliable and accurate results than the diagnosis methods based on Dempster-Shafer evidence theory. | XU Xiaobin LIU Ping SUN Yanbo WEN Chenglin | 2014 | Chinese Journal of Electronics2014，23，4： | 7 |
| 14 | Wide-steering-angle high-resolution optical phased array显示文摘Optical phased array(OPA)technology is considered a promising solution for solid-state beam steering to supersede the traditional mechanical beam steering.As a key component of the LIDAR system for long-range detection,OPAs featuring a wide steering angle and high resolution without beam aliasing are highly desired.However,a wide steering range requires a waveguide pitch less than half of the wavelength,which is easily subjected to cross talk.Besides,high resolution requires a large aperture,and it is normally achieved by a high count number of waveguides,which complicates the control system.To solve the mentioned issues,we design two high-performance 128-channel OPAs fabricated on a multilayered SiN-on-SOI platform.Attributed to the nonuniform antenna pitch,only 128 waveguides are used to achieve a 4 mm wide aperture.Besides,by virtue of innovative dual-level silicon nitride(Si_(3)N_(4))waveguide grating antennas,the fishbone antenna OPA achieves a 100°×19.4°field of view(FOV)with divergence of 0.021°×0.029°,and the chain antenna OPA realizes a 140°×19.23°FOV with divergence of 0.021°×0.1°.To our best knowledge,140°is the widest lateral steering range in two-dimensional OPA,and 0.029°is the smallest longitudinal divergence.Finally,we embed the OPA into a frequency-modulated continuous-wave system to achieve 100 m distance measurement.The reflected signal from 100 m distance is well detected with 26 dBm input transmitter power,which proves that OPA serves as a promising candidate for transceiving optical signal in a LIDAR system. | YINGZHI LI BAISONG CHEN QUANXIN NA QIJIE XIE MIN TAO LANXUAN ZHANG ZIHAO ZHI YUXUAN LI XIAOBIN LIU XIANSHU LUO GUOQIANG LO FENGLI GAO XUEYAN LI JUNFENG SONG | 2021 | Photonics Research2021，9，12： | 7 |
| 15 | Optimization design of GaN betavoltaic microbattery显示文摘Betavoltaic radioisotope microbatteries have gradually become the research direction of micro-power sources because of their several advantages,including small scale,stable output performance,long service life,high energy density,strong anti-jamming capability,and so on.Based on the theory of semiconductor physics,the current paper presented a design scheme of isotope microbattery with wide-gap semiconductor material GaN and isotope 147Pm.In consideration of the isotope's self-absorption effect,the current paper studied and analyzed the optimization thickness of semiconductor and isotope source,junction depth,depletion region thickness,doping concentration,and the generation and collection of electron hole pairs with simulation of transport process of beta particles in semiconductor material using Monte Carlo simulation program MCNP.In the proposed design scheme,for a single decay,an average energy of 28.2 keV was deposited in the GaN,and the short circuit current density,open circuit voltage,and efficiency of a single device were 1.636 μA/cm2,3.16 V,and 13.4%,respectively. | TANG XiaoBin LIU YunPeng DING Ding CHEN Da | 2012 | Science China(Technological Sciences)2012，55，3： | 5 |
| 16 | Catalytic Co9S8 decorated carbon nanoboxes as efficient cathode host for long-life lithium-sulfur batteries显示文摘Lithium sulfur(Li-S)batteries with high specific capacity and energy density can bring enormous opportunities for the nextgeneration energy storage systems.However,the severe dissolution and shuttle effect of lithium polysulfides(LiPSs)is still the key issue that seriously impedes the development of practical Li-S batteries.Here,polar Co9S8 inlaid carbon nanoboxes(Co9S8@C NBs)have been investigated as cathode host for high-performance Li-S batteries.In this integrated structure,Co9S8 nanocrystals not only provide strong chemisorptive capability for polar LiPSs,but also act as a catalyst to accelerate polysulfide redox reactions;while carbon nanobox with large inner space can offer enough space to relieve the volume expansion and physically confine LiPSs’dissolution.As a result,the S/Co9S8@C NBs cathode exhibits high specific capacity at 1C and the capacity retention was^83%after 400 cycles,corresponding to an average decay rate of only^0.043%per cycle. | Weiwei Sun Yujie Li Shuangke Liu Qingpeng Guo Yuhao Zhu Xiaobin Hong Chunman Zheng Kai Xie | 2020 | Nano Research2020，13，8： | 5 |
| 17 | Endothelial cells modified by adenovirus vector containing nine copies hypoxia response elements and human vascular endothelial growth factor as the novel seed cells for bone tissue engineering显示文摘Vascularization 在为骨头织物工程的新治疗学的策略的发展期间是热点之一,它能减轻 hypoxic 情形并且阻止移植失败。脉管的 endothelial 生长因素(VEGF ) 基因 transfection 使用 recombinant 侵入人体气管粘膜的病菌(广告) 向量能有效地支持 angiogenesis,但是 VEGF 的不受管束的长期的连续表示带安全担心。这里,我们构造了包含 HRE 倡导者和 hVEGF165 基因的九个拷贝的 recombinant 广告向量,它保存了组织缺氧可诱导的 factor-1/hypoxia 反应元素(HIF-1/HRE ) 的氧敏感。在进人的脐的静脉 endothelial 房间(HUVEC ) 的 transfection 以后, hVEGF165 mRNA 和蛋白质层次响应组织缺氧是高得多的,作为分别地由 RT-PCR 和 ELISA 揭示了。而且, Ad-9HRE-hVEGF165 向量有效地在 hypoxic 条件下面支持了增长,移植和 HUVEC 的试管形成。因此,我们相信 Ad-9HRE-hVEGF165 向量能贡献 vascularization 的规定,哪个可以在骨头织物工程期间为 hVEGF165 的表达式的更好的控制提供一条新途径(吗?作者 2017。代表生物化学和房间生物学的研究所由牛津大学出版社出版了,为生物科学的上海研究所,中国科学院。版权所有。为权限,请发邮件:journals.permissions@oup.com。) | Xiaobin Song Liang Shi Lamei Chen Xinyu Liu Xun Qu Ketao Wang Fengcai Wei | 2017 | Acta Biochimica et Biophysica Sinica2017，49，11： | 5 |
| 18 | Dynamic changes in cerebral microcirculation and hypoxia in the early stages of diffuse axonal injury显示文摘This study demonstrated that damage to the cerebral microvasculature,the formation of microthrombi and swelling of vascular endothelial cells occur early and peak 12 hours after injury in a rat model of diffuse axonal injury.Moreover,these pathological changes were most evident in the cerebral cortex.Cerebral microcirculatory dysfunction peaked later and had a shorter duration than axonal injury.In addition,the radioactive imaging agent,99Tcm-4,9-diaza-2,3,10,10-tetramethyldodecan-2,11-dione dioxime,was used to visualize the dynamic changes that occur in tissue with cerebral hypoxia.The results demonstrated that cerebral hypoxia occurs at an early stage in diffuse axonal injury.Cerebral hypoxia was evident 12 hours after injury and declined slightly 24 hours after injury,but was significantly higher than in the control group.The pathological changes that underpin microcirculatory dysfunction did not occur at the same time as axonal injury,but did occur simultaneously with neuronal injury.Cerebral hypoxia plays a key role in promoting the secondary brain injury that occurs after diffuse axonal injury. | Jinning Song Xiaobin Liu Jingyu Chen Fenru Zhang Lei Xi | 2011 | Neural Regeneration Research2011，6，20： | 5 |
| 19 | Experimental study of photooxidation products of ethylbenzene显示文摘Smog chamber experiments were performed to investigate the composition of products formed from photooxidation of aromatic hydrocarbon ethylbenzene.Vacuum ultraviolet photoionization mass spectrometer and aerosol time-of-flight mass spectrometer were used to measure the products in the gas and particle phases in real-time.Experimental results demonstrated that ethylphenol,methylglyoxal,phenol,benzaldehyde,and 2-ethylfurane were the predominant photooxidation products in both the gas and particle phases.However,there were some dierences between detected gas phase products and those of particle phase,for example,2-ethylfurane,ethylglyoxylic acid,nitroethylbenzene,3,4-dioxopentanal and ethyl-nitrophenol were only existing in the particle-phase. The possible reaction mechanisms leading to these products were also discussed and proposed. | Mingqiang Huang Weijun Zhang Liqing Hao Zhenya Wang Li Fang Ruihong Kong Xiaobin Shan Fuyi Liu Liusi Sheng | 2010 | Journal of Environmental Sciences2010，22，10： | 5 |
| 20 | Laser probe ^(40)Ar/^(39)Ar dating for quartz from auriferous quartz veins in the Shihu gold deposit,western Hebei Province,North China显示文摘The Shihu gold deposit is situated in the central shear zone of the Meso-Cenozoic Fuping metamorphic core complex in the middle-northern part of the Taihang Mountains.This kind of gold deposits named after 'Shihu type' widely occurs in this region.Gold-bearing quartz veins are their most important industrial orebodies.Detailed laser 40Ar/39Ar geochronology of the mineralized quartz veins in the study area reveals details of its tectono-magmatic history.The 40Ar/39Ar ages for the quartz are between 134.4 Ma and 155.9 Ma with a mean age of 141±4 Ma on the isochron line and 139±7 Ma on the inverse isochron line,respectively,which is interpreted to be the best estimate of the crystalline age of the quartz veins.The gold mineralization was most likely related to an underplating event that took place in the northern part of the Taihang Mountain at ca.140 Ma.The timing of gold mineralization in the area is similar to those observed in other major gold-producing provinces in the NCC.This episode is simultaneous with those in the eastern NCC,indicative of a widespread late Yanshanian metallogenic event that was a response either to the subduction of the Izanagi-Pacific plate beneath eastern China or to the removal of the Early Cretaceous lithosphere in the eastern NCC.The ore-forming material sources may be the Early Precambrian metamorphic basement,instead of intermediate-acid rock bodies and dykes. | CAO Ye LI Shengrong ZHANG Huafeng AO Chong LI Zhenzhen LIU Xiaobin | 2010 | Chinese Journal Of Geochemistry2010，29，4： | 5 |
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