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| 1 | Review of the biological and engineering aspects of algae to fuels approach显示文摘Current biofuel production relies on limited arable lands on the earth,and is impossible to meet the biofuel demands.Oil producing algae are alternative biofuel feedstock with potential to meet the world’s ambitious goal to replace fossil fuels.This review provides an overview of the biological and engineering aspects in the production and processing technologies and recent advances in research and development in the algae to fuels approach.The article covers biology,selection and genetic modification of algae species and strains,production systems design,culture media and light management,harvest and dewatering,downstream processing,and environment and economic assessment.Despite the many advances made over several decades,commercialization of algal fuels remains challenging chiefly because of the techno-economic constraints.Technological breakthroughs in all major aspects must take place before commercial production of algal fuels becomes economically viable. | Paul Chen Min Min Yifeng Chen Liang Wang Yecong Li Qin Chen Chenguang Wang Yiqin Wan Xiaoquan Wang Yanling Cheng Shaobo Deng Kevin Hennessy Xiangyang Lin Yuhuan Liu Yingkuan Wang Blanca Martinez Roger Ruan | 2009 | International Journal of Agricultural and Biological Engineering2009，2，4： | 9 |
| 2 | The critical role of inorganic nanofillers in solid polymer composite electrolyte for Li+transportation显示文摘Compared with commercial lithium batteries with liquid electrolytes,all-solidstate lithium batteries(ASSLBs)possess the advantages of higher safety,better electrochemical stability,higher energy density,and longer cycle life;therefore,ASSLBs have been identified as promising candidates for next-generation safe and stable high-energy-storage devices.The design and fabrication of solid-state electrolytes(SSEs)are vital for the future commercialization of ASSLBs.Among various SSEs,solid polymer composite electrolytes(SPCEs)consisting of inorganic nanofillers and polymer matrix have shown great application prospects in the practice of ASSLBs.The incorporation of inorganic nanofillers into the polymer matrix has been considered as a crucial method to achieve high ionic conductivity for SPCE.In this review,the mechanisms of Li+transport variation caused by incorporating inorganic nanofillers into the polymer matrix are discussed in detail.On the basis of the recent progress,the respective contributions of polymer chains,passive ceramic nanofillers,and active ceramic nanofillers in affecting the Li+transport process of SPCE are reviewed systematically.The inherent relationship between the morphological characteristics of inorganic nanofillers and the ionic conductivity of the resultant SPCE is discussed.Finally,the challenges and future perspectives for developing high-performance SPCE are put forward.This review aims to provide possible strategies for the further improvement of ionic conductivity in inorganic nanoscale filler-reinforced SPCE and highlight their inspiration for future research directions. | Zhichuan Shen Yifeng Cheng Shuhui Sun Xi Ke Liying Liu Zhicong Shi | 2021 | Carbon Energy2021，3，3： | 4 |
| 3 | Conversion characteristics and mechanism analysis of gaseous dichloromethane degraded by a VUV light in different reaction media显示文摘The photodegradation of gaseous dichloromethane(DCM) by a vacuum ultraviolet(VUV) light in a spiral reactor was investigated with different reaction media and initial concentrations.Through the combination of direct photolysis,O 3 oxidation and HO· oxidation,DCM was ultimately mineralized into inorganic compounds(such as HCl,CO 2,H 2 O,etc.) in the air with relative humidity(RH) of 75%-85%.During the photodegradation process,some small organic acids(including formic acid,acetic acid) were also detected and the intermediates were more soluble than DCM,providing a possibility for its combination with subsequent biodegradation.Based on the detected intermediates and the confirmed radicals,a photodegradation pathway of DCM by VUV was proposed.With RH 75%-80% air as the reaction medium,the DCM removal followed the second-order kinetic model at inlet concentration of 100-1000 mg/m 3.Kinetic analysis showed that the reaction media affected the kinetic constants of DCM conversion by a large extent,and RH 80% air could cause a much lower half-life for its conversion.Such results supported the possibility that VUV photodegradation could be used not only for the mineralization of DCM but also as a pretreatment before biodegradation. | Jianming Yu Wenji Cai Jianmeng Chen Li Feng Yifeng Jiang Zhuowei Cheng | 2012 | Journal of Environmental Sciences2012，24，10： | 4 |
| 4 | Adoptively transferred donor IL-17-producing CD4^(+) T cells augment, but IL-17 alleviates, acute graft-versus-host disease显示文摘The role of IL-17 and IL-17-producing CD4^(+) T cells in acute graft-versus-host disease(GVHD)has been controversial in recent mouse and human studies.We carried out studies in a murine acute GVHD model of fully major histocompatibility complex-mismatched myeloablative bone marrow transplantation.We showed that donor wild-type CD4^(+) T cells exacerbated acute GVHD compared with IL-17−/−CD4^(+) T cells,while IL-17 reduced the severity of acute GVHD.The augmentation of acute GVHD by transferred donor IL-17-producing CD4^(+) T cells was associated with increased Th1 responses,while IL-17 decreased the percentages of Th1 cells in the GVHD target organs.Furthermore,IL-17 reduced the infiltration of macrophages into the GVHD tissues.In vitro study showed that IL-17 could downregulate Th1 responses,possibly through inhibiting IL-12 production by donor macrophages.Depletion of macrophages in vivo diminished the protective effect of IL-17.Our results demonstrated the differential roles of adoptively transferred donor IL-17-producing CD4^(+) T cells and IL-17 in the same acute GVHD model. | Yifeng Cai Shoubao Ma Yuejun Liu Huanle Gong Qiao Cheng Bo Hu Yan Wu Xiao Yu Chen Dong Kai Sun Depei Wu Haiyan Liu | 2018 | Cellular & Molecular Immunology2018，15，3： | 3 |
| 5 | Kinetic analysis and bacterium metabolization of α-pinene by a novel identified Pseudomonas sp.strain显示文摘Biodegradation has become a popular alternative remediation technology for its economic and ecological advantages.An aerobic bacterium(strain ZW) capable of degrading α-pinene was isolated from a biofilter by a selective enrichment.Based on the 16S rRNA gene analysis and physiochemical properties,this strain was identified as Pseudomonas veronii.Under the optimized condition achieved by the response surface methodology(RSM),as well as pH 6.82,temperature 26.3℃ and NaCl concentration 1.36%,almost 100% α-pinene could be removed within 45 hr.Enzymatic biodegradation by the crude intracellular enzyme could be described well by the Michaelis-Menten model in which the maximum degradation rate V max and the half-saturation constant K m were calculated to be 0.431 mmol/(L·min) and 0.169 mmol/L,respectively.Activity assay of catechol suggested that the strain ZW possessed a catechol1,2-dioxygenase and could decompose benzene-ring through ortho ring cleavage.Based on the identified intermediates by GC/MS,a new metabolic pathway was proposed,in which the final metabolites were some simpler organic and inorganic compounds.The present work demonstrated that the strain ZW would have a great application prospect for the remediation of α-pinene-contaminated environment. | Zhuowei Cheng Pengfei Sun Yifeng Jiang Lili Zhang Jianmeng Chen | 2012 | Journal of Environmental Sciences2012，24，10： | 3 |
| 6 | Polymersome-mediated cytosolic delivery of cyclic dinucleotide STING agonist enhances tumor immunotherapy显示文摘Cyclic dinucleotides(CDNs)as stimulator of interferon genes(STING)agonists capable of inducing strong antitumor innate immune response are highly promising for tumor immunotherapy.The efficacy of these CDNs is,however,reduced greatly by their fast clearance,poor cell uptake and inefficient cytosolic transportation.Here,we report that reduction-responsive biodegradable chimaeric polymersomes(CPs)markedly enhance tumor retention and cytosolic delivery of a synthetic CDN,ADU-S100,and bolster STING pathway activation in the tumor microenvironment and tumor draining lymph nodes,giving significantly better tumor repression and survival of B16F10 melanoma-bearing mice compared with free CDN control.The superiority of CPs-mediated CDN delivery is further verified in combination therapy with low-dose fractionated radiation,which brings about clearly stronger and longer-term immunotherapeutic effects and protection against tumor re-challenge.The development of nano-STING agonists that are able to overcome the delivery barriers of CDNs represents an effective strategy to potentiate cancer immunotherapy. | Huan Zheng Beibei Guo Xinyun Qiu Yifeng Xia Yan Qu Liang Cheng Fenghua Meng Zhiyuan Zhong | 2022 | Bioactive Materials2022，7，10： | 2 |
| 7 | Exploring the heavy air pollution in Beijing in the fourth quarter of 2015: assessment of environmental benefits for red alerts显示文摘 | Teng NIE Lei NIE Zhen ZHOU Zhanshan WANG Yifeng XUE Jiajia GAO Xiaoqing WU Shoubin FAN Linglong CHENG | 2018 | Frontiers of Earth Science2018，12，2： | 2 |
| 8 | Removal characteristics and kinetic analysis of an aerobic vapor-phase bioreactor for hydrophobic alpha-pinene显示文摘Biofiltration is considered an effective method to control volatile organic compounds(VOCs) pollution.This study was conducted to evaluate the potential use of a bacterial biofilter packed with wood chips and peat for the removal of hydrophobic α-pinene.When inoculated with two pure degraders and adapted activated sludge,a removal efficiency(RE) of more than 95% was achieved after a startup period of 11 days.The maximum elimination capacity(EC) of 50 g/(m 3 ·hr) with RE of 94% was obtained at empty bed retention time(EBRT) of 102 sec.When higher α-pinene concentrations and shorter EBRTs were applied,the REs and ECs decreased significantly due to mass-transfer and biological reaction limitations.As deduced from the experimental results,approximately 74% of α-pinene were completely mineralized by the consortiums and the biomass yield was 0.60 g biomass/g α-pinene.Sequence analysis of the selected bands excised from denaturing gradient gel electrophoresis revealed that the inoculated pure cultures could be present during the whole operation,and others were closely related to bacteria being able to degrade hydrocarbons.The kinetic results demonstrated that the whole biofiltration for α-pinene was diffusion-limit controlled owing to its hydrophobic characteristics.These findings indicated that this bacterial biofiltration is a promising technology for the remediation of hydrophobic industrial waste gases containing α-pinene. | Yifeng Jiang Shanshan Li Zhuowei Cheng Runye Zhu Jianmeng Chen | 2012 | Journal of Environmental Sciences2012，24，8： | 2 |
| 9 | Isolation of new thermophilicaerobiobacteria which produce thermostable α-amylase显示文摘 | Fengxie Jin Xiaomei Cheng Yifeng Shi | 1990 | J G en Appl Microbial1990，36，： | 1 |
| 10 | Feasibility of sentinel lymph node biopsy omission after integration of ^(18)F-FDG dedicated lymph node PET in early breast cancer: a prospective phase II trial显示文摘Objective:Sentinel lymph node biopsy(SLNB)is currently the standard of care in clinically node negative(cN0)breast cancer.The present study aimed to evaluate the negative predictive value(NPV)of 18F-FDG dedicated lymph node positron emission tomography(LymphPET)in cN0 patients.Methods:This was a prospective phase II trial divided into 2 stages(NCT04072653).In the first stage,cN0 patients underwent axillary LymphPET followed by SLNB.In the second stage,SLNB was omitted in patients with a negative preoperative axillary assessment after integration of LymphPET.Here,we report the results of the first stage.The primary outcome was the NPV of LymphPET to detect macrometastasis of lymph nodes(LN-macro).Results:A total of 189 patients with invasive breast cancer underwent LymphPET followed by surgery with definitive pathological reports.Forty patients had LN-macro,and 16 patients had only lymph node micrometastasis.Of the 131 patients with a negative LymphPET result,16 patients had LN-macro,and the NPV was 87.8%.After combined axillary imaging evaluation with ultrasound and LymphPET,100 patients were found to be both LymphPET and ultrasound negative,9 patients had LN-macro,and the NPV was 91%.Conclusions:LymphPET can be used to screen patients to potentially avoid SLNB,with an NPV>90%.The second stage of the SOAPET trial is ongoing to confirm the safety of omission of SLNB according to preoperational axillary evaluation integrating LymphPET. | Junjie Li Jingyi Cheng Guangyu Liu Yifeng Hou Genghong Di Benglong Yang Yizhou Jiang Liang Huang Feilin Qu Sheng Chen Yan Wang Keda Yu Zhimin Shao | 2022 | Cancer Biology & Medicine2022，19，7： | 1 |
| 11 | Heterointerface Engineering of β‑Chitin/Carbon Nano‑Onions/Ni-P Composites with Boosted Maxwell‑Wagner‑Sillars Effect for Highly Efficient Electromagnetic Wave Response and Thermal Management显示文摘The rational construction of microstructure and composition with enhanced Maxwell-Wagner-Sillars effect(MWSE)is still a challenging direction for reinforcing electromagnetic wave(EMW)absorption performance,and the related EMW attenuation mechanism has rarely been elucidated.Herein,MWSE boostedβ-chitin/carbon nano-onions/Ni–P composites is prepared according to the heterointerface engineering strategy via facile layer-by-layer electrostatic assembly and electroless plating techniques.The heterogeneous interface is reinforced from the aspect of porous skeleton,nanomaterials and multilayer construction.The composites exhibit competitive EMW response mechanism between the conductive loss and the polarization/magnetic loss,as describing like the story of“The Hare and the Tortoise”.As a result,the composites not only achieve a minimum reflection loss(RL_(min))of−50.83 dB and an effective bandwidth of 6.8 GHz,but also present remarkable EMW interference shielding effectiveness of 66.66 dB.In addition,diverse functions such as good thermal insulation,infrared shielding and photothermal performance were also achieved in the hybrid composites as a result of intrinsic morphology and chemicophysics properties.Therefore,we believe that the boosted MWSE open up a novel orientation toward developing multifunctional composites with high-efficient EMW response and thermal management. | Fei Pan Lei Cai Yuyang Shi Yanyan Dong Xiaojie Zhu Jie Cheng Haojie Jiang Xiao Wang Yifeng Jiang Wei Lu | 2022 | Nano-Micro Letters2022，14，5： | 1 |
| 12 | A microRNA-135a/b binding polymorphism in CD133 confers decreased risk and favorable prognosis of lung cancer in Chinese by reducing CD133 expression显示文摘 | Mei Cheng Lei Yang Rongrong Yang Xiaorong Yang Jieqiong Deng Bolan Yu Dongsheng Huang Shuxu Zhang Hui Wang Fuman Qiu Yifeng Zhou Jiachun Lu | 2013 | Carcinogenesis2013，，10： | 1 |
| 13 | Development of a rapid and sensitive LC–MS/MS assay for the determination of combretastatin A4 phosphate, combretastatin A4 and combretastatin A4 glucuronide in beagle dog plasma and its application to a pharmacokinetic study显示文摘 | Xiaojing Wang Zhihang Chen Jinjing Che Qingfang Meng Chengqi Shan Yunan Hou Xiaolei Liu Yifeng Chai Yuanguo Cheng | 2009 | Journal of Chromatography B2009，，30： | 1 |
| 14 | Liver-specific microRNA-185 knockout promotes cholesterol dysregulation in mice显示文摘Background:The liver plays a key role in regulating whole body cholesterol homeostasis.Hepatic cholesterol accumulation causes liver injury in fatty liver disease and hypercholesterolemia increases the risk of cardiovascular disease.MicroRNAs(miRNAs,miRs)have been shown to regulate various pathways in cholesterol metabolism.Recently,miR-185 has been shown to regulate sterol regulatory element-binding protein 2(SREBP2)and low-density lipoprotein receptor(LDLR)to modulate cholesterol syn-thesis and uptake.Materials and methods:The role of miR-185 in regulating diet-induced metabolic disorders were studied in liver-specific miRNA-185 knockout(L-miR-185 KO)mice.Results:L-miR-185 KO mice developed worsened hepatic steatosis upon high-fat high-cholesterol Western diet feeding with accumulation of triglyceride and cholesterol in the liver.In addition,L-miR-185 KO mice developed hypercholesterolemia upon Western diet feeding.Gene expression analysis showed that L-miR-185 KO mice did not show increased hepatic mRNA expression of SREBP2 or its targets LDLR and HMG-CoA reductase(HMGCR).Although expression of miR-185 mimic inhibited the mRNA of SREBP2,HMGCR and LDLR in HepG2 cells,miR-185 inhibitor did not increase the mRNA of SREBP2,HMGCR or LDLR in HepG2 cells.Conclusions:In conclusion,we reported that L-miR-185 KO mice were more sensitive to Western diet induced hepatic steatosis and hypercholesterolemia.The molecular mechanisms underlying these metabolic changes remain to be investigated in future studies. | Cheng Chen David Matye Yifeng Wang Tiangang Li | 2021 | Liver Research2021，5，4： | 1 |
| 15 | Isolation of new thermophilic aerobic bacteria which produce thermostable α-amylase显示文摘 | Jin Fengxie Cheng Xiaomei Shi Yifeng | 1990 | J of General and Applied Microbiology1990，36，： | 1 |
| 16 | Con- version characteristics and kinetic analysis of gaseous α-pinene degraded by a VUV light in various reaction media 显示文摘 | CHENG Zhuowei JIANG Yifeng ZHANG L L | 2011 | Sepa- ration and Purification Technology2011，77，1： | 1 |
| 17 | Advantages of Si, Sbz Te phase-change material and its applications in phase?change random access memory显示文摘 | Gu Yifeng Cheng Yan | 2011 | Sci pta Materilia2011，65，： | 1 |
| 18 | Chemical components and properties of core - shell acrylate latex containing fluorine in the shell and their films 显示文摘 | Yanjun Chen Shiyuan Cheng Yifeng Wang | 2006 | Journal of Applied Polymer Science2006，99，： | 1 |
| 19 | Improving Li Plating Behaviors Through Cu-Sn Alloy-Coated Current Collector for Dendrite-Free Lithium Metal Anodes显示文摘Alloy anode with good reversibility of lithium plating/stripping and long cycling stability is considered as promising anode materials.Here,Cu-Sn alloy is used as the substrate for Li deposition to induce the most densely packed arrangement of Li atoms,thus presenting high lithiophilicity and improving Li plating behaviors.The LiFePO4-based full cell with the asprepared dendrite-free Li metal anode retained at 85 mAh g-1 with a high coulombic efficiency of 99.5% after 300 cycles,presenting a capacity retention of 79.4%.This strategy provides a new perspective to structure dendrite-free Li anode for the next-generation high-energy density batteries. | Yifeng Cheng Xi Ke Zhicong Shi | 2021 | Acta Metallurgica Sinica(English Letters)2021，34，3： | 0 |
| 20 | Deep Learning Trackers Review and Challenge显示文摘Recently,deep learning has achieved great success in visual tracking.The goal of this paper is to review the state-of-the-art tracking methods based on deep learning.First,we categorize the existing deep learning based trackers into three classes according to network structure,network function and network training.For each categorize,we analyze papers in different categories.Then,we conduct extensive experiments to compare the representative methods on the popular OTB-100,TC-128 and VOT2015 benchmarks.Based on our observations.We conclude that:(1)The usage of the convolutional neural network(CNN)model could significantly improve the tracking performance.(2)The trackers with deep features perform much better than those with low-level hand-crafted features.(3)Deep features from different convolutional layers have different characteristics and the effective combination of them usually results in a more robust tracker.(4)The deep visual trackers using end-to-end networks usually perform better than the trackers merely using feature extraction networks.(5)For visual tracking,the most suitable network training method is to per-train networks with video information and online fine-tune them with subsequent observations.Finally,we summarize our manuscript and highlight our insights,and point out the further trends for deep visual tracking. | Yongxiang Gu Beijing Chen Xu Cheng Yifeng Zhang Jingang Shi | 2019 | Journal of Information Hiding and Privacy Protection2019，1，1： | 0 |
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