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| 1 | Adverse factors increase preeclampsia-like changes in pregnant mice with abnormal lipid metabolism显示文摘 | Ding Xiaoyan Yang Zi Han Yiwei Yu Huan | 2014 | Chinese Medical Journal2014，，15： | 18 |
| 2 | Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline(updated version)显示文摘The novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is the cause of a rapidly spreading illness,coronavirus disease 2019(COVID-19),affecting more than seventeen million people around the world.Diagnosis and treatment guidelines for clinicians caring for patients are needed.In the early stage,we have issued'A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV)infected pneumonia(standard version)';now there are many direct evidences emerged and may change some of previous recommendations and it is ripe for develop an evidence-based guideline.We formed a working group of clinical experts and methodologists.The steering group members proposed 29 questions that are relevant to the management of COVID-19 covering the following areas:chemoprophylaxis,diagnosis,treatments,and discharge management.We searched the literature for direct evidence on the management of COVID-19,and assessed its certainty generated recommendations using the Grading of Recommendations,Assessment,Development and Evaluation(GRADE)approach.Recommendations were either strong or weak,or in the form of ungraded consensus-based statement.Finally,we issued 34 statements.Among them,6 were strong recommendations for,14 were weak recommendations for,3 were weak recommendations against and 11 were ungraded consensus-based statement.They covered topics of chemoprophylaxis(including agents and Traditional Chinese Medicine(TCM)agents),diagnosis(including clinical manifestations,reverse transcription-polymerase chain reaction(RT-PCR),respiratory tract specimens,IgM and IgG antibody tests,chest computed tomography,chest X-ray,and CT features of asymptomatic infections),treatments(including lopinavirritonavir,umifenovir,favipiravir,interferon,remdesivir,combination of antiviral drugs,hydroxychloroquine/chloroquine,interleukin-6 inhibitors,interleukin-1 inhibitors,glucocorticoid,qingfei paidu decoction,lianhua qingwen granules/capsules,convalescent plasma,lung transplantation,invasive or noninvasive ventilation,and extracorporeal membrane oxygenation(ECMO)),and discharge management(including discharge criteria and management plan in patients whose RT-PCR retesting shows SARS-CoV-2 positive after discharge).We also created two figures of these recommendations for the implementation purpose.We hope these recommendations can help support healthcare workers caring for COVID-19 patients. | Ying-Hui Jin Qing-Yuan Zhan Zhi-Yong Peng Xue-Qun Ren Xun-Tao Yin Lin Cai Yu-Feng Yuan Ji-Rong Yue Xiao-Chun Zhang Qi-Wen Yang Jianguang Ji Jian Xia Yi-Rong Li Fu-Xiang Zhou Ya-Dong Gao Zhui Yu Feng Xu Ming-Li Tu Li-Ming Tan Min Yang Fang Chen Xiao-Ju Zhang Mei Zeng Yu Zhu Xin-Can Liu Jian Yang Dong-Chi Zhao Yu-Feng Ding Ning Hou Fu-Bing Wang Hao Chen Yong-Gang Zhang Wei Li Wen Chen Yue-Xian Shi Xiu-Zhi Yang Xue-Jun Wang Yan-Jun Zhong Ming-Juan Zhao Bing-Hui Li Lin-Lu Ma Hao Zi Na Wang Yun-Yun Wang Shao-Fu Yu Lu-Yao Li Qiao Huang Hong Weng Xiang-Ying Ren Li-Sha Luo Man-Ru Fan Di Huang Hong-Yang Xue Lin-Xin Yu Jin-Ping Gao Tong Deng Xian-Tao Zeng Hong-Jun Li Zhen-Shun Cheng Xiao-Mei Yao Xing-Huan Wang | 2020 | Military Medical Research2020，7，3： | 6 |
| 3 | Association between socioeconomic status and chronic obstructive pulmonary disease in Jiangsu province, China: a population-based study显示文摘Background:Chronic obstructive pulmonary disease(COPD)is a common public health problem worldwide.Recent studies have reported that socioeconomic status(SES)is related to the incidence of COPD.This study aimed to investigate the association between SES and COPD among adults in Jiangsu province,China,and to determine the possible direct and indirect effects of SES on the morbidity of COPD.Methods:A cross-sectional study was conducted among adults aged 40 years and above between May and December of 2015 in Jiangsu province,China.Participants were selected using a multistage sampling approach.COPD,the outcome variable,was diagnosed by physicians based on spirometry,respiratory symptoms,and risk factors.Education,occupation,and monthly family average income(FAI)were used to separately indicate SES as the explanatory variable.Mixed-effects logistic regression models were introduced to calculate odds ratios(ORs)and 95%confidence intervals(CIs)for examining the SES-COPD relationship.A pathway analysis was conducted to further explore the pulmonary function impairment of patients with different SES.Results:The mean age of the 2421 participants was 56.63±9.62 years.The prevalence of COPD was 11.8%(95%CI:10.5%–13.1%)among the overall sample population.After adjustment for age,gender,residence,outdoor and indoor air pollution,body weight status,cigarette smoking,and potential study area-level clustering effects,educational attainment was negatively associated with COPD prevalence in men;white collars were at lower risk(OR:0.60,95%CI:0.43–0.83)of experiencing COPD than blue collars;compared with those within the lower FAI subgroup,participants in the upper(OR:0.68,95%CI:0.49–0.97)tertiles were less likely to experience COPD.Such negative associations between all these three SES indicators and COPD were significant among men only.Education,FAI,and occupation had direct or indirect effects on pulmonary function including post-bronchodilator forced expiratory volume in 1 s/forced vital capacity(FEV1/FVC),FEV1,FVC,and FEV1 percentage of predicted.Education,FAI,and occupation had indirect effects on pulmonary function indices of all participants mainly through smoking status,indoor air pollution,and outdoor air pollution.We also found that occupation could affect post-bronchodilator FEV1/FVC through body mass index.Conclusions:Education,occupation,and FAI had an adverse relationship with COPD prevalence in Jiangsu province,China.SES has both direct and indirect associations with pulmonary function impairment.SES is of great significance for COPD morbidity.It is important that population-based COPD prevention strategies should be tailored for people with different SES. | Dan-Dan Zhang Jian-Nan Liu Qing Ye Zi Chen Ling Wu Xue-Qing Peng Gan Lu Jin-Yi Zhou Ran Tao Zhen Ding Fei Xu Linfu Zhou | 2021 | Chinese Medical Journal2021，，13： | 5 |
| 4 | A novel approach for designing efficient broadband photodetectors expanding from deep ultraviolet to near infrared显示文摘Broadband photodetection(PD)covering the deep ultraviolet to near-infrared(200–1000 nm)range is significant and desirable for various optoelectronic designs.Herein,we employ ultraviolet(UV)luminescent concentrators(LC),iodinebased perovskite quantum dots(PQDs),and organic bulk heterojunction(BHJ)as the UV,visible,and near-infrared(NIR)photosensitive layers,respectively,to construct a broadband heterojunction PD.Firstly,experimental and theoretical results reveal that optoelectronic properties and stability of CsPbI3 PQDs are significantly improved through Er3+doping,owing to the reduced defect density,improved charge mobility,increased formation energy,tolerance factor,etc.The narrow bandgap of CsPbI3:Er3+PQDs serves as a visible photosensitive layer of PD.Secondly,considering the matchable energy bandgap,the BHJ(BTP-4Cl:PBDB-TF)is selected as to NIR absorption layer to fabricate the hybrid structure with CsPbI3:Er3+PQDs.Thirdly,UV LC converts the UV light(200–400 nm)to visible light(400–700 nm),which is further absorbed by CsPbI3:Er3+PQDs.In contrast with other perovskites PDs and commercial Si PDs,our PD presents a relatively wide response range and high detectivity especially in UV and NIR regions(two orders of magnitude increase that of commercial Si PDs).Furthermore,the PD also demonstrates significantly enhanced air-and UV-stability,and the photocurrent of the device maintains 81.5%of the original one after 5000 cycles.This work highlights a new attempt for designing broadband PDs,which has application potential in optoelectronic devices. | Nan Ding Yanjie Wu Wen Xu Jiekai Lyu Yue Wang Lu Zi Long Shao Rui Sun Nan Wang Sen Liu Donglei Zhou Xue Bai Ji Zhou Hongwei Song | 2022 | Light(Science & Applications)2022，11，5： | 5 |
| 5 | Correlation between the different chain lengths of free fatty acid oxidation and abili .ty of trophoblastic invasion显示文摘 | Yu Huan Yang Zi Ding Xiaoyan Wang Yanling Han Yiwei | 2014 | Chinese Medical Journal2014，，19： | 5 |
| 6 | Differences in Liver Injury and Trophoblastic Mitochondrial Damage in Different Preeclampsia-like Mouse Models显示文摘 | Yi-Wei Han Zi Yang Xiao-Yan Ding Huan Yu | 2015 | Chinese Medical Journal2015，，12： | 3 |
| 7 | Mechanisms of Rhenium on Wettability and Interactions Between Nickel-Base Superalloy Melt and Al2O3-Based Ceramic Material显示文摘A systematic study on the wettability and interactions between superalloy melts with various Re contents and Al2 O3-based ceramic moulds was presented in this paper.It was found that the increase of Re content inhibited the interfacial reactions to some extent.With regard to the 0,1.5 and 3 Re alloys,a double reaction layer containing Al2 O3 and HfO2 was formed at the interface,but the thickness of reaction layer decreased with the increase of Re content.However,only Al2 O3 phase was detected at the interface when the content of Re was 6 wt%,and the interface reaction was the weakest and the thickness of reaction layer was the thinnest.The wetting angle of the alloy/ceramic system increased as the level of Re increased.Moreover,the formation of viscous sand at the interface mainly depended on the change of wetting angle of the system. | Yun Zi Jie Meng Chaowei Zhang Yizhou Zhou Yutian Ding | 2020 | Acta Metallurgica Sinica(English Letters)2020，33，7： | 3 |
| 8 | Object registration for remote sensing images using robust kernel pattern vectors显示文摘The registration of multitemperal remote sensing images before and after a disaster is a challenging problem.The main reason is that there is a dearth of homologous features that can be used as tie points for registration of variform objects.This paper proposes a new registration method based on robust kernel pattern vector(KPV) for water objects in the remote sensing images,which have complex deformation before and after a disaster.We show how the variform objects can be precisely registered using their robust kernel pattern vectors(RKPVs).The contribution can be divided into three parts.First,a novel shape descriptor,named as kernel pattern vector(KPV),is defined.Second,a robust kernel principal component analysis(RKPCA) method is proposed,which can not only capture the common pattern of the variform objects but can also act as the Criterion for outlier detection.Finally,a registration approach is derived based on the implicit RKPVs.We demonstrate the power of the proposed approach by comparing it with other existing methods using two real cases:one for lake monitoring in the Jiayu region,and the other for damage mapping of earthquake-induced barrier lake at Tangjiashan(2008 Wenchuan Earthquake).The results show that the method is effective in capturing the common structural pattern of the variform objects before and after a disaster. | DING MingTao JIN Zi TIAN Zheng DUAN XiFa ZHAO Wei YANG LiJuan | 2012 | Science China(Information Sciences)2012，55，11： | 3 |
| 9 | Rapid Internal Control Reference Recombinase-Aided Amplification Assays for EBV and CMV Detection显示文摘Epstein-Barr virus(EBV)and cytomegalovirus(CMV),two of the most prevalent human herpesviruses,cause a wide spectrum of diseases and symptoms and are associated with serious health problem.In this study,we developed an internal control reference recombinase-aided amplification(ICR-RAA)assay for the rapid detection of EBV and CMV within 30 min.The assay had a sensitivity of 5 and 1 copies/test for EBV and CMV,respectively,with no cross reaction with other pathogens.In comparison with those of the commercial quantitative polymerase chain reaction(qPCR),the sensitivity of the EBV and CMV ICR-RAAs using extracted DNA was 93.33%and 84.84%,respectively;the specificity was 98.75%and 100.00%,respectively;and the Kappa values were 0.930 and 0.892(P<0.05),respectively.In comparison with those of qPCR,the sensitivity of the EBV and CMV ICR-RAAs using the DNA by thermal lysis was 72.22%and 80.00%,respectively;the specificity was 100.00%。 | GAO Yuan TIE Yan Qing ZHAO Lin Qing TAN He DING Nan DING Ya Xin GUO Qi ZHANG Rui Qing WANG Jin Rong CHEN Zi Wei FAN Guo Hao SHEN Xin Xin FENG Zhi Shan MA Xue Jun | 2021 | Biomedical and Environmental Sciences2021，34，8： | 3 |
| 10 | Gait Analysis of Quadruped Robot Using the Equivalent Mechanism Concept Based on Metamorphosis显示文摘The previous research regarding the gait planning of quadruped robot focuses on the sequence for lifting o and placing the feet, but neglects the influence of body height. However, body height a ects gait performance significantly, such as in terms of the stride length and stability margin. We herein study the performance of a quadruped robot using the equivalent mechanism concept based on metamorphosis. Assuming the constraints between standing feet and the ground with hinges, the ground, standing legs and robot body are considered as a parallel mechanism, and each swing leg is regarded as a typical serial manipulator. The equivalent mechanism varies while the robot moves on the ground. One gait cycle is divided into several periods, including step forward stages and switching stages. There exists a specific equivalent mechanism corresponding to each gait period. The robot's locomotion can be regarded as the motion of these series of equivalent mechanisms. The kinematics model and simplified model of the equivalent mechanism is established. A new definition of the multilegged robot stability margin, based on friction coe cient, is presented to evaluate the robot stability. The stable workspaces of the equivalent mechanism in the step forward stage of trotting gait under di erent friction coe cients are analyzed. The stride length of the robots is presented by analyzing the relationship between the stable workspaces of the equivalent mechanisms of two adjacent step forward stages in one gait cycle. The simulation results show that the stride length is larger with increasing friction coe cient. We herein propose a new method based on metamorphosis, and an equivalent mechanism to analyze the stability margin and stable workspace of the multilegged robot. | Kun Xu Peijin Zi Xilun Ding | 2019 | Chinese Journal of Mechanical Engineering2019，32，1： | 3 |
| 11 | Circulating Neutrophil Counts Decrease in Response to Mitigated Air Quality in Stable COPD Patients显示文摘这三年的研究基于呼吸疾病(格子) 的广州研究所,长期的妨碍的肺的疾病(COPD ) Biobank,在 36 个 COPD 病人被进行估计在白血球,红血球,血红素,和血小板的层次的变化是否与在空气污染物质集中的变化有关。每天,没有 2 层次展出了基线年和 2010 亚洲比赛时期之间的重要差别。我们在白血球和 neutrophils 计数层次观察了重要减小,在 15.51% 和 23.01% ,从亚洲人前比赛到在期间 -- 亚洲运动会分别地。在亚洲人以后的比赛时期,大多数污染物质接近了亚洲人前比赛时期层次,和类似的效果在白血球和嗜中性的计数被表明。为两项条款,我们识别了重要增加源于没提高 2 在落后天 0-2/5-6。我们断定在污染物质的减小在 COPD 与 hematological 事件的 inactivation 在干预时期期间被联系。 | ZHANG Zi Li WANG Jian LIU Fen DING Ming Jing LIU Fei CHEN Si Fan LU Wen Ju | 2018 | Biomedical and Environmental Sciences2018，31，1： | 3 |
| 12 | An alternative surgical technique for varicoceles:a preliminary experience of the microsurgical spermatic(distal end)-inferior or superficial epigastric vein anastomosis in symptomatic varicoceles associated with perineal pain显示文摘Many therapies are effective in treating varicoceles,including dilation of the pampiniform plexus in males.The most common method of treatment is varicocelectomy.We aimed to assess an alternative technique(microsurgical spermatic[distal end]-superficial or inferior epigastric vein anastomosis)that preserves the normal blood flow pattern for varicocele treatment.We retrospectively analyzed 27 men with varicocele between October 2019 and July 2020.All patients underwent microsurgical spermatic(distal end)-superficial or inferior epigastric vein anastomosis.The prognosis was reviewed retrospectively with an additional survey conducted 3 months after surgery.The mean±standard deviation of the age was 26.1±7.3 years in patients with microsurgical spermatic(distal end)-superficial or inferior epigastric vein anastomosis.The maximum diameter of the varicocele vein,perineal pain score,sperm density,and forward movement of sperm improved over 3 months after surgery.Microsurgical spermatic(distal end)-superficial or inferior epigastric vein anastomosis is a safe and efficient surgical treatment for varicoceles. | Zi Wan Hai-Ming Cao Bi-Cheng Yang Yong Gao Li Ding Peng Luo Guang-Wen Yang Lin Ma Chun-Hua Deng | 2022 | Asian Journal of Andrology2022，24，6： | 2 |
| 13 | A novel interface for interractive exploration of DTI fibers显示文摘 | CHEN Wei DING Zi' ang ZHANG Song | 2012 | IEEE Transations on Visual- ization and Computer Graphics2012，15，6： | 1 |
| 14 | The whole family of kinematic structures for planar 2-and 3-DOF fractionated kinematic chains 显示文摘 | Ding Huafeng Zi Bin Huang Peng | 2013 | Mechanism and Machine Theory2013，70，： | 1 |
| 15 | Design and analysis of cooperative cable parallel manipulators for multiple mobile cranes显示文摘 | ZI Bin QIAN Sen DING Huafeng | 2012 | International journal of advanced robotic systems2012，9，： | 1 |
| 16 | Investigation of isothermal curing behaviour dur- ing the synthesis of polybenzoxazine-layered silicate nanocomposites via cyclic monomer 显示文摘 | SHI ZI XING YU DING SHENG WANG YI ZHONG | 2002 | Eur Polym J2002，38，： | 1 |
| 17 | Cancer-associated histone mutation H2BG53D disrupts DNA–histone octamer interaction and promotes oncogenic phenotypes显示文摘Dear Editor,Recent studies from us and others have deciphered the clinical relevance of a variety of oncohistones1 in different diseases.The H3K27M and H3K36M mutant histones exert dominant-negative effects on methylation levels of histone H3K27 and H3K36 on wildtype histone protein in pediatric brain cancers2–4 and chondroblastoma,5,6 respectively.In contrast to H3K27M and H3K36M that act in trans to cause global reduction of methylation at the respective residues,the H3G34 mutations,including H3G34V/R and H3G34W/L found in pediatric high-grade glioma and giant cell tumor of the bone,affect the H3K36 methylation in cis and alter the H3K36 methylation on the nucleosome containing the H3G34 mutation(s). | Yi Ching Esther Wan Tsz Chui Sophia Leung Dongbo Ding Xulun Sun Jiaxian Liu Lina Zhu Tze Zhen Evangeline Kang Du Yang Yuchen Zhang Jitian Zhang Chengmin Qian Michael Shing Yan Huen Qing Li Maggie Zi Ying Chow Zongli Zheng Junhong Han Ajay Goel Xin Wang Toyotaka Ishibashi Kui Ming Chan | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 1 |
| 18 | Design and analysis of cooperative cable parallel manipulators for multiple mobile cranes显示文摘 | Zi B Qian S Ding H | 2012 | International Journal of Advanced Robotic System2012，9，207： | 1 |
| 19 | Design and analysis of cooperative cable parallel manipulators for multiple mobile cranes 显示文摘 | ZI Bin SEN Qian DING Hua feng | 2012 | International Journal of Advanced Robotic Systems2012，9，207： | 1 |
| 20 | Porous Ni@Pt Core‐Shell Nanotube Array Electrocatalyst with High Activity and Stability for Methanol Oxidation显示文摘 | Liang‐Xin Ding Gao‐Ren Li Zi‐Long Wang Zhao‐Qing Liu Hong Liu Ye‐Xiang Tong | 2012 | Chem. Eur. J2012，，27： | 1 |
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